Abstract:
:This article reviews the recent dermatopathology literature involving nonmelanocytic neoplasia, with a focus on important work done over the last 5 years. The discussion includes advances in the understanding of Merkel cell carcinoma pathogenesis and prognosis; changes in the seventh edition of the American Joint Committee of Cancer staging manual in reference to staging of squamous cell carcinoma and Merkel cell carcinoma; newly described or rare histopathologic patterns and entities including squamoid eccrine ductal carcinoma, rippled-pattern adnexal neoplasms, onychomatricoma, spindle cell predominant trichodiscoma/neurofollicular hamartoma, and myoepithelioma; and microsatellite instability in sebaceous neoplasms of Muir-Torre syndrome and other tumors.
journal_name
Dermatol Clinjournal_title
Dermatologic clinicsauthors
Sidhu HK,Patel RV,Goldenberg Gdoi
10.1016/j.det.2012.06.009subject
Has Abstractpub_date
2012-10-01 00:00:00pages
623-41, viissue
4eissn
0733-8635issn
1558-0520pii
S0733-8635(12)00079-4journal_volume
30pub_type
杂志文章,评审abstract::Photodynamic therapy (PDT) has had a rapid insurgence into the dermatologic armamentarium of clinicians from all over the world. Its use in actinic keratoses and in non-melanoma skin cancers is well described. Additional uses, including its use in the treatment of photorejuvenation and acne vulgaris and related disord...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/j.det.2006.09.013
更新日期:2007-01-01 00:00:00
abstract::Many substances have historically been used to address facial soft tissue defects. Currently in the United States autologous fat and injectable bovine collagen are the most commonly utilized injectable fillers. Additionally, the judicious application of BOTOX in the upper face as well as neck has all but revolutionize...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70469-1
更新日期:1997-10-01 00:00:00
abstract::Though history will mark June 1981 as the birthday of the AIDS pandemic, the first true case of the syndrome and its cause originated years before in West-Central Africa. History also highlights the irony that the discovery of AIDS, the detection of its cause, and the development of drugs for its treatment, all occurr...
journal_title:Dermatologic clinics
pub_type: 历史文章,杂志文章
doi:10.1016/j.det.2006.05.001
更新日期:2006-10-01 00:00:00
abstract::To remain experts in skin care and treatment, every dermatologist must be aware of the evolving role of soft tissue fillers in dermatology. Patients with facial scarring, lipodystrophy, contour abnormalities, and age- and sun-induced rhytids can be successfully treated. A literature review, industry recommendations, a...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2004.09.009
更新日期:2005-04-01 00:00:00
abstract::The large-scale deployment of low-cost, noninvasive mechanisms of early detection are needed to reduce the melanoma burden. A serial 2-step system could power mass screening efforts serving the uninsured and underinsured as well as the rural and remote US counties where melanoma mortality is doubled for lack of access...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2017.06.005
更新日期:2017-10-01 00:00:00
abstract::The only spiders of real medical importance to humans in the United States are the Loxosceles and Latrodectus species, primarily the brown recluse and the black window, respectively. These spiders bite humans only when trapped or crushed against the skin. Severe brown recluse spider bites produce dermonecrosis within ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1990-04-01 00:00:00
abstract::The basis of in-office evaluation of leg vascular disease involves Doppler ultrasound to estimate flow in arteries and veins. Arterial evaluation localizes sites of obstruction by segmental pressures obtained by Doppler signal assessment using pressure cuffs. Ankle compared with brachial arterial pressure is the most ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
abstract::Light therapy is widely used in dermatology. An enhancement to his therapy is the use of a photosensitizing medication along with light therapy, known as photodynamic therapy (PDT). PDT is primarily used for the treatment of precancerous lesions, acne vulgaris, and nonmelonoma skin cancer, and has also been shown to i...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/j.det.2006.09.010
更新日期:2007-01-01 00:00:00
abstract::This article provides a protocol for the systematic approach to the technique of Mohs micrographic surgery. Each step, from tumor excision and tissue mapping, to specimen processing and histologic interpretation, through wound closure and postoperative management, is covered. The advantages of Mohs surgery over other ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2011.02.002
更新日期:2011-04-01 00:00:00
abstract::The eyebrows, eyelashes, and eyelids are important protective structures for the eye and are also of considerable cosmetic value. The dermatologist should understand the available cosmetic and surgical techniques for helping patients with eyebrow loss, eyelash loss, and dermatochalasis. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1992-10-01 00:00:00
abstract::Diaper dermatitis is a term used to encompass a wide range of inflammatory processes that occur in the area covered by the diaper. The term "diaper dermatitis" is thus simply a description of the location of a rash. Numerous factors can be involved in the pathogenesis of dermatitis in the diaper area. These factors, i...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::This article contains a potpurri of surgically related stratagems, alternative techniques, and philosophies. These surgical pearls have been selected for their simplicity, usefulness, and applicability. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1989-01-01 00:00:00
abstract::Skin cancer is reaching epidemic levels in the United States. Recent advances in the understanding of the pathophysiology of melanoma have allowed improved risk stratification in the revised American Joint Committee on Cancer (AJCC) criteria, new tests to capture patients at higher risk than their stage may indicate, ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2018.08.003
更新日期:2019-01-01 00:00:00
abstract::This article describes that the diagnosis of melanoma has improved with such tools as epiluminescence microscopy. There remain, however, a number of unusual types of melanoma that are difficult to diagnose by virtue of their atypical or subtle morphology. The prognosis of these melanomas is often worse than for their ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(02)00036-0
更新日期:2002-10-01 00:00:00
abstract::Although the Mohs technique is most often applied to moderate and large lesions, with appropriate modifications it can also be applied to massive lesions. Reconstructive procedures after resection of large defects are also discussed. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1989-10-01 00:00:00
abstract::In order to be considered an ectodermal dysplasia, a disorder should meet the following criteria: it must be congenital; it must be diffuse (not localized) and must involve the epidermis as well as at least one of its appendages; and it must not be progressive. Included is a discussion of some well-documented, as well...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::This article has shown that all the necessary components for successful control of gonorrhea are available. In developed countries, general improvements in economic conditions and advances in treatment and diagnosis have resulted in the lowest incidence rates of gonorrhea ever. Within these countries, however, control...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/s0733-8635(05)70036-x
更新日期:1998-10-01 00:00:00
abstract::Patients who present with concerns that they suffer from sexually transmitted infection frequently suffer from other problems. Occasionally it is simply not enough just to demonstrate that the patient has no evidence of sexually transmitted disease, but it is important to diagnose the cause of their symptoms and to re...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/s0733-8635(05)70046-2
更新日期:1998-10-01 00:00:00
abstract::The terms "palisaded neutrophilic and granulomatous dermatitis," "interstitial granulomatous dermatitis," and the subset "interstitial granulomatous drug reaction" are a source of confusion. There exists substantial overlap among the entities with few strict distinguishing features. We review the literature and highli...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2015.03.005
更新日期:2015-07-01 00:00:00
abstract::The unique properties of lasers create an enormous potential for specific therapy of skin diseases. As with any new device, the most efficacious and appropriate use requires an understanding of the mechanisms of light interaction with tissue as well as the properties of the laser itself. Modification of current lasers...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1993-01-01 00:00:00
abstract::Antimalarial compounds have been demonstrated to be both safe and efficacious in the treatment of lupus erythematosus as well as several other dermatologic conditions. It is imperative, however, that physicians familiarize themselves with the potential complications associated with the use of these agents. Furthermore...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1992-07-01 00:00:00
abstract::Epidermolysis bullosa (EB) in Mexico continues to be a rare genodermatosis that is still unknown for most of the health care professionals in the country. The spirit of DebRA MEXICO was born in 1994 when the Mexican health care team started to see patients with the main purpose to provide medical care, genetic counsel...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2010.02.014
更新日期:2010-04-01 00:00:00
abstract::Although clinical trials for new drugs are often limited in children because of safety concerns or restrictions, new therapies or novel strategies with old drugs have recently expanded dermatologic armamentarium for pediatric patients. Oral propranolol is currently the first choice in the treatment of alarming infanti...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/j.det.2010.03.005
更新日期:2010-07-01 00:00:00
abstract::As with other chemical-based industries, the pharmaceutical industry has the potential for innumerable irritants and allergens. Prompt reporting and recognition of employees' skin diseases, with clarification of the triggering factors, can lead to appropriate control and prevention in many situations. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1994-07-01 00:00:00
abstract::There has been a resurgence over the past decade of microlipoinjection. Adipose tissue has proved to be a safe and effective filler substance for subcutaneous defects. More recently, lipocytic dermal augmentation, or autologous collagen, has been used to correct dermal defects. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1995-04-01 00:00:00
abstract::Calciphylaxis is defined by the presence of calcium deposits within the wall of small and medium-sized vessels. It is classically considered a life-threatening disease in patients with end-stage renal disease under dialysis. Clinically, it is characterized by the presence of painful plaques surrounded by a reticulate ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2008.05.006
更新日期:2008-10-01 00:00:00
abstract::Based on the disagreements about the role of atopy in the condition known as atopic dermatitis, it is not surprising that there have been divergent views concerning the appropriate treatment of the disease. A large population of physicians, including most dermatologists and some allergists, believe that the fundamenta...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1986-01-01 00:00:00
abstract::Pediatric dermatologic disease that have specific therapies and/or specific prophylactic measures are reviewed. Herpes simplex virus and varicella-zoster virus infections, human papillomavirus infections, and molluscum contagiosum infections are discussed with special emphasis on recent advances of therapy and prophyl...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70251-5
更新日期:1998-07-01 00:00:00
abstract::Sensitive skin is a complex problem with genetic, individual, environmental, occupational, and ethnic implications. Further work is needed to rank irritants and irritant reactions to classify sensitive skin on the basis of standard models. The development of topical products designed for sensitive and ethnic skin may ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1991-01-01 00:00:00
abstract::With simple, inexpensive therapy, virtually all venous ulcers heal without the need for hospitalization, skin grafting, growth factors, hyperbaric oxygen, or debilitating bed rest. Although the future promises to yield a greater understanding about the nature of these wounds and ways to treat them, one can benefit the...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1993-10-01 00:00:00