Abstract:
:Tetracyclines are known to exhibit multiple significant anti-inflammatory actions. This article describes the mechanisms of this anti-inflammatory activity, such as inhibition of chemotaxis, granuloma formation, and protease. The article also discusses the effectiveness of tetracyclines in treating such diseases as acne vulgaris, rosacea, bullous dermatoses, granulomatous disease, and livedo vasculitis.
journal_name
Dermatol Clinjournal_title
Dermatologic clinicsauthors
Webster G,Del Rosso JQdoi
10.1016/j.det.2007.01.012subject
Has Abstractpub_date
2007-04-01 00:00:00pages
133-5, vissue
2eissn
0733-8635issn
1558-0520pii
S0733-8635(07)00013-7journal_volume
25pub_type
杂志文章,评审abstract::The progress in research on OLP and other autoimmune diseases has been significant. Coupled with a growing recognition of the clinical features and treatment options by dentists and physicians and fueled by the advances in immunosuppressive therapies, research will undoubtedly provide new insights into this complex di...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(02)00067-0
更新日期:2003-01-01 00:00:00
abstract::With simple, inexpensive therapy, virtually all venous ulcers heal without the need for hospitalization, skin grafting, growth factors, hyperbaric oxygen, or debilitating bed rest. Although the future promises to yield a greater understanding about the nature of these wounds and ways to treat them, one can benefit the...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1993-10-01 00:00:00
abstract::Advances in laser technology now permit the physician to provide an effective form of treatment for a large variety of cutaneous disorders for which no previous therapy or only poor forms of therapy previously existed. Additional refinements in both laser instruments and treatment techniques are certain to have a prof...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1987-04-01 00:00:00
abstract::Cyanoacrylates (CAs) were not widely adopted for medical use until recently because of lingering concerns regarding the initial tissue toxicities of the short-chain CAs. The medium-chain CAs, primarily butyl-cyanoacrylate, have been widely used in Europe and Canada for several decades and have gone a long way in dispe...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2004.09.003
更新日期:2005-04-01 00:00:00
abstract::Contact dermatitis is the most common occupational skin disorder, responsible for up to 30% of all cases of occupational disease in industrialized nations. Epidemiologic data suggest that contact dermatitis accounts for 90% to 95% of all cases of occupational skin disease, imposing considerable social and economic imp...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2009.05.002
更新日期:2009-07-01 00:00:00
abstract::Cutaneous manifestations of thyroid disease are protean in nature and can be divided into specific lesions such as the thyroglossal duct cyst and cutaneous metastases from thyroid malignancy, nonspecific signs secondary to thyroid hormone imbalance, and associated dermatologic and systemic disorders. This review repre...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(02)00009-8
更新日期:2002-07-01 00:00:00
abstract::The only spiders of real medical importance to humans in the United States are the Loxosceles and Latrodectus species, primarily the brown recluse and the black window, respectively. These spiders bite humans only when trapped or crushed against the skin. Severe brown recluse spider bites produce dermonecrosis within ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1990-04-01 00:00:00
abstract::Many lesions that appear in the oral cavity manifest as a nodule or swelling. A particular lesion may have the clinical characteristics of several entities, and a differential diagnosis should be generated, with a final diagnosis reached by microscopic examination. This article discusses and shows the clinical feature...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70362-4
更新日期:1996-04-01 00:00:00
abstract::A hypothesis is proposed for the etiopathogenesis of some cases of Hodgkin's disease, Sezary's syndrome, and related disorders that compose the cutaneous T-cell lymphoma group. This new model, termed the thymus bypass model, is discussed in detail in this article. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1994-04-01 00:00:00
abstract::Although new technologies are becoming available to aid in diagnosis, the skin biopsy continues to be the fundamental tool of the dermatologist to evaluate the nature of a pigmented lesion. There are 3 major techniques for the biopsy of a pigmented lesion: shave biopsy, punch/incisional biopsy, and excisional biopsy. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2012.04.013
更新日期:2012-07-01 00:00:00
abstract::In this article, the authors summarize the published literature on the reliability and accuracy of teledermatology. The first section reports on the diagnostic reliability of teledermatology compared with face-to-face clinic consultation. In the second section, the authors report on the "intragroup" diagnostic agreeme...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2008.11.012
更新日期:2009-04-01 00:00:00
abstract::Dermatologists helped to develop the specialty of liposuction surgery and contributed to many of the innovations and instrumentation in this field. Dermatologists were trained side by side with other cosmetic surgeons as the procedure was introduced into the United States. Dermatologists have been important in teachin...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract::Objectively evaluating disease activity in autoimmune bullous disease (AIBD) is important in terms of the clinical assessment of patients and as an outcome measure for clinical trials. Measures need to be general enough to capture the issues specific to each of the bullous dermatoses but specific enough to capture any...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2011.03.015
更新日期:2011-07-01 00:00:00
abstract::Ocular melanomas are the most common intraocular malignancy in adults. The majority of ocular melanomas are choroidal melanomas. These tumors can be difficult to diagnose, especially when they are small. Documented growth of a lesion on serial examinations is the most important clinical feature favoring the diagnosis ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1992-10-01 00:00:00
abstract::If one looks at the development of most drugs, it becomes evident that an extended period of time is necessary before the proper use and full range of activities of the drug in treating human disease become apparent. In many cases, initial treatment failures are due to faulty expectations as well as inadequate dosing ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1993-10-01 00:00:00
abstract::Rickettsialpox is a member of the spotted-fever group of the rickettsioses and results from an infection with Rickettsia akari. This microbe is transmitted by the bite of the house-mouse mite Liponyssoides sanguineus. Patents experience fevers, sweats, headaches, and a vesicular eruption over the trunk and extremities...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70439-3
更新日期:1997-04-01 00:00:00
abstract::I would like to stress that there seem to be three subpopulations of neural crest-derived melanocytes in the body that can be functionally and morphologically distinguished: the cutaneous melanocytes, which continuously synthesize small melanosomes to be transferred to keratinocytes; the uveal melanocytes, which synth...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1988-04-01 00:00:00
abstract::Pemphigus is an autoimmune intraepithelial blistering disease of the skin and mucous membranes that is characterized in part by the presence of circulating IgG autoantibodies. These autoantibodies, which have been shown to be pathogenic, bind to complexes on the keratinocyte cell surface and have been utilized to esta...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1990-10-01 00:00:00
abstract::Normal and malignant pigment cells are known targets for many hormones. Besides alpha-melanocyte-stimulating hormone and the steroidal hormones estrogen, testosterone, and glucocorticoids, factors produced by other epidermal cells can affect melanization and proliferation of pigment cells. Among those factors are the ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1988-04-01 00:00:00
abstract::Occupational contact dermatitis in hairdressers is a common clinical dermatologic problem. Apparently often secondary to irritant contact dermatitis caused by shampooing in Europe, in North America, allergic contact dermatitis related to the chemicals handled, especially oxidation dyes and permanent waving components,...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Chromoblastomycosis is a chronic cutaneous infection due to several varieties of pigmented fungi. Diagnosis is straightforward and based on clinical and microscopic findings. Despite the protracted course of the disease, dissemination of the infection is rare. New insights into the pathophysiology may permit a closer ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70327-2
更新日期:1996-01-01 00:00:00
abstract::The unique properties of lasers create an enormous potential for specific therapy of skin diseases. As with any new device, the most efficacious and appropriate use requires an understanding of the mechanisms of light interaction with tissue as well as the properties of the laser itself. Modification of current lasers...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1993-01-01 00:00:00
abstract::The goal of photochemotherapy in psoriasis is to attempt to lower the number of exposures and the total cumulative doses while still maintaining good control of the disease. PUVA has been modified by using better psoralen preparations and more effective light sources, and it also has been combined with other treatment...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1995-10-01 00:00:00
abstract::This article reviews the role of dermatologists in occupational dermatologic care by reviewing the types of skin diseases that may be work-related, the diagnostic testing, and evidence of quality of care delivery and outcomes provided by dermatologists. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70169-8
更新日期:2000-04-01 00:00:00
abstract::This article provides an overview of the resurfacing technique of dermabrasion. Preoperative consultation, perioperative medications, postoperative management, common complications, and reasonable outcome expectations are all described in detail. A description of proper technique, intraoperative equipment, and an appr...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/s0733-8635(05)70284-9
更新日期:2001-07-01 00:00:00
abstract::Dermatologic infections are treated to improve the elderly patient's quality of life and prevent disability and death. Pharmacokinetic changes, social issues, and the risk for adverse effects and drug interactions, however, increase the challenge to achieve successful treatment of those over age 65 as compared with yo...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(03)00112-8
更新日期:2004-01-01 00:00:00
abstract::An overview of the therapeutic possibilities of acute wounds, ulcers, and infected or colonized wounds is given. This article reviews therapeutic approaches and nonsurgical dermatologic treatments in particular. The types of wounds discussed include acute wounds, infected acute wounds, chronic wounds, infected and col...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70019-x
更新日期:1998-04-01 00:00:00
abstract::Photodynamic therapy (PDT) has had a rapid insurgence into the dermatologic armamentarium of clinicians from all over the world. Its use in actinic keratoses and in non-melanoma skin cancers is well described. Additional uses, including its use in the treatment of photorejuvenation and acne vulgaris and related disord...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/j.det.2006.09.013
更新日期:2007-01-01 00:00:00
abstract::Among the different classes and complexities of antiretroviral regimens, maximal viral suppression, sustained durability, increased CD4 count, decreased evolving resistance, and fewer side effects combined with increased compliance resulting in decreased morbidity and mortality remain the goals of therapy. Serial vira...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70314-4
更新日期:2001-10-01 00:00:00
abstract::Chloracne is a rare but important acneiform eruption often associated with the ingestion of chlorinated phenolic agents such as dioxins with subsequent toxicity from these chemicals. Clinically, chloracne can be distinguished from acne vulgaris by the distribution and appearance of the lesions and by taking a detailed...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1990-01-01 00:00:00