The thymus bypass model. A new hypothesis for the etiopathogenesis of mycosis fungoides and related disorders.

abstract：:Discolorations of the skin, such as vitiligo, were recognized thousands of years ago. White spots caused by vitiligo and other disorders have caused significant social opprobrium to those disfigured by these pigmentary disorders, throughout history and still in the present day. Treatments have been desperately sought ...

journal_title：Dermatologic clinics

authors： Nordlund JJ

更新日期：2017-04-01 00:00:00

abstract：:There has been a resurgence over the past decade of microlipoinjection. Adipose tissue has proved to be a safe and effective filler substance for subcutaneous defects. More recently, lipocytic dermal augmentation, or autologous collagen, has been used to correct dermal defects. ...

journal_title：Dermatologic clinics

authors： Pinski KS,Coleman WP 3rd

更新日期：1995-04-01 00:00:00

abstract：:Nail psoriasis, melanonychia striata, and onychomycosis are relatively common nail disorders that have generated much research into their pathophysiology and treatment. The authors hope this discussion of the recent therapeutic developments for treating these disorders will not only inform but will also inspire furthe...

journal_title：Dermatologic clinics

authors： Van Laborde S,Scher RK

更新日期：2000-01-01 00:00:00

abstract：:Black patients who desire cosmetic surgery have not had many treatment options or services available to them. At this time, the requests for specific cosmetic surgical procedures by black patients have far exceeded the number of cosmetic surgeons able to meet their needs. A surgeon who calls himself or herself a cosme...

journal_title：Dermatologic clinics

authors： Pierce HE Jr

更新日期：1988-07-01 00:00:00

abstract：:Porphyria cutanea tarda is a photocutaneous syndrome characterized clinically by cutaneous fragility, bullae, hypertrichosis, pigmentary changes, and sclerodermoid plaques and characterized biochemically by hepatic overproduction and storage of excessive amounts of porphyrins. Porphyria cutanea tarda, the most common ...

journal_title：Dermatologic clinics

authors： Grossman ME,Poh-Fitzpatrick MB

更新日期：1986-04-01 00:00:00

abstract：:The recalcitrance of rosacea to many treatment options may prompt patients to spend exorbitant amounts of money on unsubstantiated treatment regimens in an effort to achieve relief. The authors examine the relationship between disease severity and treatment cost across several demographic and socioeconomic strata. Fam...

journal_title：Dermatologic clinics

authors： Turbeville JG,Alinia H,Tuchayi SM,Bahrami N,Cardwell LA,Awosika O,Richardson I,Huang KE,Feldman SR

更新日期：2018-04-01 00:00:00

abstract：:The only spiders of real medical importance to humans in the United States are the Loxosceles and Latrodectus species, primarily the brown recluse and the black window, respectively. These spiders bite humans only when trapped or crushed against the skin. Severe brown recluse spider bites produce dermonecrosis within ...

journal_title：Dermatologic clinics

authors： Wilson DC,King LE Jr

更新日期：1990-04-01 00:00:00

abstract：:The systematic evaluation of photosensitive patients involves a comprehensive history, physical examination, phototesting, and, if necessary, photopatch testing and laboratory evaluation. Polymorphous light eruption, chronic actinic dermatitis, solar urticaria, and photosensitivity secondary to systemic medications ar...

journal_title：Dermatologic clinics

authors： Choi D,Kannan S,Lim HW

更新日期：2014-07-01 00:00:00

abstract：:Understanding the anatomy and distribution of facial fat and the alterations that occur during the aging process is essential to effectively and precisely achieve facial rejuvenation. Over the past several years, through cadaveric dissections and computed tomographic studies, much has been discovered concerning the ad...

journal_title：Dermatologic clinics

authors： Fitzgerald R,Rubin AG

更新日期：2014-01-01 00:00:00

abstract：:This article provides an overview of the resurfacing technique of dermabrasion. Preoperative consultation, perioperative medications, postoperative management, common complications, and reasonable outcome expectations are all described in detail. A description of proper technique, intraoperative equipment, and an appr...

journal_title：Dermatologic clinics

authors： Harmon CB

更新日期：2001-07-01 00:00:00

abstract：:Hepatic itch remains among the most agonizing symptoms for affected patients and a major clinical challenge for physicians. Pruritus may occur in almost all liver diseases, particularly those with cholestatic features. Hepatic itch arises irrespective of the severity of the underlying liver disease or extent of choles...

journal_title：Dermatologic clinics

authors： Düll MM,Kremer AE

更新日期：2018-07-01 00:00:00

abstract：:Gardner's syndrome is an autosomal dominant genodermatosis. Familial polyposis of the colon, osteomas, and cutaneous epidermoid cysts are characteristic features. Colon cancer will develop in all affected individuals unless prophylactic colectomy is performed. The follow-up and management of patients with Gardner's sy...

journal_title：Dermatologic clinics

authors： Perniciaro C

更新日期：1995-01-01 00:00:00

abstract：:Guttate and plaque psoriasis are regarded as variants of one disease but present with distinct clinical and histologic appearances. This article focuses special attention on different pathways in the development and clinical course of each, with emphasis on immunologic correlations regarding HLA system linkage and the...

journal_title：Dermatologic clinics

authors： Christophers E,Kiene P

更新日期：1995-10-01 00:00:00

abstract：:As the study of vulvar diseases becomes more accepted and as physicians and patients become more comfortable discussing vulvar complaints, there will also be less hesitancy to examine the area adequately. This can only lead to better observations, more knowledge, and more exact diagnosis and treatment of these problem...

journal_title：Dermatologic clinics

authors： Turner ML

更新日期：1992-04-01 00:00:00

abstract：:Calciphylaxis is defined by the presence of calcium deposits within the wall of small and medium-sized vessels. It is classically considered a life-threatening disease in patients with end-stage renal disease under dialysis. Clinically, it is characterized by the presence of painful plaques surrounded by a reticulate ...

journal_title：Dermatologic clinics

authors： Daudén E,Oñate MJ

更新日期：2008-10-01 00:00:00

abstract：:In this article, the use of selected psychopharmacologic medications was explained in detail. If a patient who is obviously suffering from a psychiatric component of his or her disorder that can be responsive to psychopharmacotherapy refuses to accept a referral to a psychiatrist or other mental health professional, t...

journal_title：Dermatologic clinics

authors： Koo JY

更新日期：1992-07-01 00:00:00

abstract：:The umbrella term psoriasis is now understood to incorporate several distinct phenotypes or endotypes along the disease spectrum that in turn will dictate different therapies. A stratified medicine approach to psoriasis using this clinical information coupled with pharmacogenomic and immunologic data will become more ...

journal_title：Dermatologic clinics

authors： Menter MA,Griffiths CE

更新日期：2015-01-01 00:00:00

abstract：:Vasculitis may be defined as damage to blood vessels induced by pathologic processes, resulting in compromise of function of the organ in which the blood vessels reside. A large number of syndromes and disease processes exist in which vasculitis plays a key role. Selected vasculitic syndromes of special interest to de...

journal_title：Dermatologic clinics

authors： Lawley TJ,Kubota Y

更新日期：1990-10-01 00:00:00

abstract：:Contact dermatitis in the United States poses a significant public health concern. This article provides a definition of contact dermatitis and its associated risk factors. The authors discuss the epidemiology of occupational contact dermatitis including its incidence and prevalence, and describe how estimates are cal...

journal_title：Dermatologic clinics

authors： Cashman MW,Reutemann PA,Ehrlich A

更新日期：2012-01-01 00:00:00

abstract：:In order to be considered an ectodermal dysplasia, a disorder should meet the following criteria: it must be congenital; it must be diffuse (not localized) and must involve the epidermis as well as at least one of its appendages; and it must not be progressive. Included is a discussion of some well-documented, as well...

journal_title：Dermatologic clinics

authors： Solomon LM,Cook B,Klipfel W

更新日期：1987-01-01 00:00:00

abstract：:Tetracyclines are known to exhibit multiple significant anti-inflammatory actions. This article describes the mechanisms of this anti-inflammatory activity, such as inhibition of chemotaxis, granuloma formation, and protease. The article also discusses the effectiveness of tetracyclines in treating such diseases as ac...

journal_title：Dermatologic clinics

authors： Webster G,Del Rosso JQ

更新日期：2007-04-01 00:00:00

abstract：:Contact dermatitis is a common skin disease caused by contact with irritants or allergens. Irritant contact dermatitis is a result of nonspecific irritant factors, which cause activation of mainly innate immunity, resulting in skin inflammation. Contact hypersensitivity, which manifests itself as allergic contact derm...

journal_title：Dermatologic clinics

authors： Fyhrquist-Vanni N,Alenius H,Lauerma A

更新日期：2007-10-01 00:00:00

abstract：:Application of caustic chemicals to improve cosmesis and reverse actinic damage has been used for centuries. Although still not an exact science, it was not until the latter part of this century that peeling became more systematized. The indications, patient selection, armamentarium, histology, comprehension of the me...

journal_title：Dermatologic clinics

authors： Matarasso SL,Glogau RG

更新日期：1991-01-01 00:00:00

abstract：:Skin disease is highly prevalent in the United States, and it has been well-documented that patients with skin disease experience financial, psychological, social, and quality-of-life (QoL) burdens beyond those of the general population. Pediatric patients and their caregivers are particularly vulnerable to the burden...

journal_title：Dermatologic clinics

authors： Brown MM,Chamlin SL,Smidt AC

更新日期：2013-04-01 00:00:00

abstract：:This article, rather than presenting an overview of all available antifungal agents, has provided an update on new information about older agents, as well as evolving information about new agents, including those currently undergoing clinical trials. Among the azoles, ketoconazole will continue to be used as a major a...

journal_title：Dermatologic clinics

authors： Lesher JL Jr

更新日期：1992-10-01 00:00:00

abstract：:Extramammary Paget disease is an intraepidermal adenocarcinoma, most often limited to the epidermis, with typical cases affecting genital skin. When limited to the epidermis, primary extramammary Paget disease is not life-threatening, but invasive disease may portend a poor prognosis. Surgical excision remains the mai...

journal_title：Dermatologic clinics

authors： Merritt BG,Degesys CA,Brodland DG

更新日期：2019-07-01 00:00:00

abstract：:Laryngo-onycho-cutaneous (LOC) syndrome was reclassified as a subtype of junctional epidermolysis bullosa (JEB) based on clinical features similar to JEB and its association, in the majority of patients from the Punjab, with a unique mutation affecting the N terminus of the alpha3 chain of LM332. Although LOC syndrome...

journal_title：Dermatologic clinics

authors： Cohn HI,Murrell DF

更新日期：2010-01-01 00:00:00

abstract：:Ivermectin is a potent antiparasitic drug and the first commercially available member of a new class of drugs (macrocyclic lactones) that has been approved for human use. Ivermectin has already proven to be highly effective in the elimination of river blindness as a public health burden. Side effects have been minor, ...

journal_title：Dermatologic clinics

authors： Elgart GW,Meinking TL

更新日期：2003-04-01 00:00:00

abstract：:The varied histopathology of the reactive inflammatory vascular dermatoses requires close cooperation between the clinician and the pathologist. This article presents an overview of the histology of this group of dermatoses, including the figurate erythemas, the pigmented purpuric eruptions, urticaria and urticarial v...

journal_title：Dermatologic clinics

authors： Solomon AR Jr

更新日期：1985-01-01 00:00:00

abstract：:Large defects may at first appear to be too big to close in a side-to-side fashion. Certain wounds and situations may call for healing with second intent. Undermining and pulley sutures are very helpful in bringing together wound edges of certain large openings. Partial closures may decrease the tendency to exert unwa...

journal_title：Dermatologic clinics

authors： Shelton RM

更新日期：2001-07-01 00:00:00