Abstract:
:Vasculitis may be defined as damage to blood vessels induced by pathologic processes, resulting in compromise of function of the organ in which the blood vessels reside. A large number of syndromes and disease processes exist in which vasculitis plays a key role. Selected vasculitic syndromes of special interest to dermatologists are discussed in this article.
journal_name
Dermatol Clinjournal_title
Dermatologic clinicsauthors
Lawley TJ,Kubota Ysubject
Has Abstractpub_date
1990-10-01 00:00:00pages
681-7issue
4eissn
0733-8635issn
1558-0520journal_volume
8pub_type
杂志文章,评审abstract::Contact dermatitis is a common skin disease caused by contact with irritants or allergens. Irritant contact dermatitis is a result of nonspecific irritant factors, which cause activation of mainly innate immunity, resulting in skin inflammation. Contact hypersensitivity, which manifests itself as allergic contact derm...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2007.06.002
更新日期:2007-10-01 00:00:00
abstract::Systemic retinoids represent a growing armamentarium in the treatment of a wide range of skin disorders and malignancies. Although these drugs can have substantial toxicities, their wise use can result in safe and efficacious therapy that can alter dramatically the lives of individuals with severe skin disorders. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70237-0
更新日期:2001-01-01 00:00:00
abstract::Normal and malignant pigment cells are known targets for many hormones. Besides alpha-melanocyte-stimulating hormone and the steroidal hormones estrogen, testosterone, and glucocorticoids, factors produced by other epidermal cells can affect melanization and proliferation of pigment cells. Among those factors are the ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1988-04-01 00:00:00
abstract::Discolorations of the skin, such as vitiligo, were recognized thousands of years ago. White spots caused by vitiligo and other disorders have caused significant social opprobrium to those disfigured by these pigmentary disorders, throughout history and still in the present day. Treatments have been desperately sought ...
journal_title:Dermatologic clinics
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.det.2016.11.001
更新日期:2017-04-01 00:00:00
abstract::Improved therapy for CTCL will depend on a better understanding of the pathogenesis of this disease at a molecular level. It is clear that the T cells in MF and CTCL do not undergo normal programmed cell death and have prolonged lifespans. Skin flora or other antigens may stimulate the initial proliferation, offering ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70155-8
更新日期:2000-01-01 00:00:00
abstract::Although clinical trials for new drugs are often limited in children because of safety concerns or restrictions, new therapies or novel strategies with old drugs have recently expanded dermatologic armamentarium for pediatric patients. Oral propranolol is currently the first choice in the treatment of alarming infanti...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/j.det.2010.03.005
更新日期:2010-07-01 00:00:00
abstract::Many substances have historically been used to address facial soft tissue defects. Currently in the United States autologous fat and injectable bovine collagen are the most commonly utilized injectable fillers. Additionally, the judicious application of BOTOX in the upper face as well as neck has all but revolutionize...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70469-1
更新日期:1997-10-01 00:00:00
abstract::Hair transplantation has developed into a refined art in the past 30 years. Refined techniques and instruments, appreciation of properly placed hairlines, better methods of harvesting donor grafts, and better cutting materials in punches have significantly improved results in one of the most frequently performed cosme...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1987-07-01 00:00:00
abstract::Exanthematous eruptions, urticaria, photosensitivity, pigmentary problems, acne, alopecia, fixed drug eruptions, and lichenoid reactions are the most common dermatologic side effects associated with the administration of psychopharmacologic agents. The cutaneous findings associated with the various eruptions and the m...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70378-8
更新日期:1996-07-01 00:00:00
abstract::Dermatologists can decrease unnecessary use of antimicrobial agents by avoiding them in situations wherein good evidence indicates that they are ineffective. Controlled trials indicate that antimicrobial agents are unhelpful in treating cutaneous abscesses, inflamed epidermal cysts, uninfected atopic eczema, and cutan...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2008.07.003
更新日期:2009-01-01 00:00:00
abstract::The Armed Forces Institute of Pathology (AFIP) is well known for providing expert pathology in many specialties and educational courses for civilian and military personnel. Some of the departments at the AFIP have also developed expertise in various advanced laboratory techniques for diagnosis and research that are ap...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70074-7
更新日期:1999-01-01 00:00:00
abstract::Men of all races are currently more open to requesting and undergoing treatments for a plethora of cosmetic concerns. Among the most common goals are procedures that combat the signs of aging, rejuvenate the skin, even out the color tone, address textural issues such as acne scarring, and improve hair disorders. Given...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2017.09.002
更新日期:2018-01-01 00:00:00
abstract::Reconstruction of the nose provides many challenges owing to its differing subunits and varied surfaces. In this article, the nasal anatomy, anesthesia, and some of the reconstructive options available to the dermatologic surgeon are reviewed. These reconstructive options are based on the subunit and depth of the defe...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70489-7
更新日期:1998-01-01 00:00:00
abstract::Traditional chemotherapies, interleukins, phosphorylase inhibitors, and proteasome inhibitors are important therapies available to patients with cutaneous T-cell lymphoma (CTCL). Traditional chemotherapies, both in combination and as single agents, are commonly used in relapsed, refractory CTCLs that behave in an aggr...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2015.05.012
更新日期:2015-10-01 00:00:00
abstract::It is quite evident the pathogenesis of psoriasis is modulated by immune-mediated mechanisms that invoke activated T cells and inflammatory cytokines, such as tumor necrosis factor-alpha. Current immunosuppressive systemic treatments may be effective in controlling psoriasis to a certain degree but have significant dr...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2003.12.002
更新日期:2004-10-01 00:00:00
abstract::The exact epidemiology of autoimmune bullous disorders in Australia is unknown. This article describes the establishment of a registry and support group to serve patients with these disorders. The registry aids research in Australia by providing epidemiologic data and maintaining an up-to-date database with patient co...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/j.det.2011.07.002
更新日期:2011-10-01 00:00:00
abstract::There has been a resurgence over the past decade of microlipoinjection. Adipose tissue has proved to be a safe and effective filler substance for subcutaneous defects. More recently, lipocytic dermal augmentation, or autologous collagen, has been used to correct dermal defects. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1995-04-01 00:00:00
abstract::I would like to stress that there seem to be three subpopulations of neural crest-derived melanocytes in the body that can be functionally and morphologically distinguished: the cutaneous melanocytes, which continuously synthesize small melanosomes to be transferred to keratinocytes; the uveal melanocytes, which synth...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1988-04-01 00:00:00
abstract::Chronic itch is a clinically challenging yet scientifically remarkable and complex process. Increasing understanding of the pathophysiology of chronic itch is leading to targeted therapeutic approaches that are now dramatically improving quality of life. This improvement will accelerate as the tools of basic and clini...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2018.02.001
更新日期:2018-07-01 00:00:00
abstract::Most melanocytic tumors can be characterized as a benign nevus or a melanoma by a trained pathologist using traditional histopathological methods. However, a minority demonstrates ambiguous features and continues to be a diagnostic challenge. Genetic expression profiling (GEP) assays have been developed in an effort t...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2017.06.016
更新日期:2017-10-01 00:00:00
abstract::This article reviews the role of dermatologists in occupational dermatologic care by reviewing the types of skin diseases that may be work-related, the diagnostic testing, and evidence of quality of care delivery and outcomes provided by dermatologists. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70169-8
更新日期:2000-04-01 00:00:00
abstract::In this article, vulvar anatomy and histology are reviewed, and nonneoplastic and neoplastic epithelial disorders are presented. Included are lichen sclerosus, squamous cell hyperplasia, vulvar intraepithelial neoplasia, vulvar Paget's disease, and squamous cell carcinoma. Current terminology, tumor measurements, and ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1992-04-01 00:00:00
abstract::Laryngo-onycho-cutaneous (LOC) syndrome was reclassified as a subtype of junctional epidermolysis bullosa (JEB) based on clinical features similar to JEB and its association, in the majority of patients from the Punjab, with a unique mutation affecting the N terminus of the alpha3 chain of LM332. Although LOC syndrome...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2009.10.010
更新日期:2010-01-01 00:00:00
abstract::Skin disease is highly prevalent in the United States, and it has been well-documented that patients with skin disease experience financial, psychological, social, and quality-of-life (QoL) burdens beyond those of the general population. Pediatric patients and their caregivers are particularly vulnerable to the burden...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2012.12.010
更新日期:2013-04-01 00:00:00
abstract::Dermatologists helped to develop the specialty of liposuction surgery and contributed to many of the innovations and instrumentation in this field. Dermatologists were trained side by side with other cosmetic surgeons as the procedure was introduced into the United States. Dermatologists have been important in teachin...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract::An overview of the therapeutic possibilities of acute wounds, ulcers, and infected or colonized wounds is given. This article reviews therapeutic approaches and nonsurgical dermatologic treatments in particular. The types of wounds discussed include acute wounds, infected acute wounds, chronic wounds, infected and col...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70019-x
更新日期:1998-04-01 00:00:00
abstract::Cosmeceuticals are understood to be active cosmetics that are sold over-the-counter, but have profound effects on skin appearance and functioning. This term has no legal meaning in the United States, because only cosmetics and pharmaceuticals are recognized by regulatory bodies. Cosmeceuticals are carefully developed ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2013.12.002
更新日期:2014-04-01 00:00:00
abstract::Adverse reactions to medications are common and may have a variety of clinical presentations in the oral cavity. Targeted therapies and new biologic agents have revolutionized the treatment of cancers, autoimmune diseases, and inflammatory and rheumatologic diseases but have also been associated with adverse events in...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2020.05.012
更新日期:2020-10-01 00:00:00
abstract::Chromoblastomycosis is a chronic cutaneous infection due to several varieties of pigmented fungi. Diagnosis is straightforward and based on clinical and microscopic findings. Despite the protracted course of the disease, dissemination of the infection is rare. New insights into the pathophysiology may permit a closer ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70327-2
更新日期:1996-01-01 00:00:00
abstract::The systematic evaluation of photosensitive patients involves a comprehensive history, physical examination, phototesting, and, if necessary, photopatch testing and laboratory evaluation. Polymorphous light eruption, chronic actinic dermatitis, solar urticaria, and photosensitivity secondary to systemic medications ar...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2014.03.006
更新日期:2014-07-01 00:00:00