Abstract:
:Skin disease is highly prevalent in the United States, and it has been well-documented that patients with skin disease experience financial, psychological, social, and quality-of-life (QoL) burdens beyond those of the general population. Pediatric patients and their caregivers are particularly vulnerable to the burden of skin disease. Over the past decade disease-specific indices for QoL measurement in pediatric dermatology have been developed. Most of this research has focused on acne, atopic dermatitis, hemangiomas, ichythosis, psoriasis, and vitiligo. This article provides an overview of QoL assessment in pediatric dermatology for these six conditions.
journal_name
Dermatol Clinjournal_title
Dermatologic clinicsauthors
Brown MM,Chamlin SL,Smidt ACdoi
10.1016/j.det.2012.12.010subject
Has Abstractpub_date
2013-04-01 00:00:00pages
211-21issue
2eissn
0733-8635issn
1558-0520pii
S0733-8635(12)00174-Xjournal_volume
31pub_type
杂志文章,评审abstract::Melanoma vaccines represent a novel and potentially effective method of slowing the progression of melanoma. This article discusses the importance in the design of vaccines for melanoma, the relative advantages and disadvantages of this approach, and summarizes the results of the most important clinical trials conduct...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70009-7
更新日期:1998-04-01 00:00:00
abstract::Papulosquamous eruptions are the most frequently seen cutaneous manifestations of human immunodeficiency virus (HIV) infection. Especially common and useful in making a diagnosis of HIV infection are seborrheic dermatitis, xerosis or ichthyosis, and a pruritic or papular eruption. There is some evidence from transgeni...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1991-07-01 00:00:00
abstract::One may accomplish certain closures without tension or distortion using blunt liposuction cannula dissection with or without suction-assisted lipectomy. If closure cannot be accomplished with adequate undermining and an appropriate flap design, the surgeon may first aspirate fat to allow use of the focally expanded sk...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1990-07-01 00:00:00
abstract::"Telemedicine" is defined as the use of telecommunication technologies for the exchange of medical information across distances. Applications include patient management as well as research and education. Teledermatology is a steadily growing category of telemedicine. This article presents general aspects of telemedici...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2007.12.003
更新日期:2008-04-01 00:00:00
abstract::Cutaneous T-cell lymphomas (CTCL) represent a heterogeneous group with respect to clinical presentation, histology, and phenotype. The most frequent CTCL represent a proliferation of x/x+ T-cell with a helper inducer memory phenotype (CD4+, CD29+, CD45RO+). ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1994-04-01 00:00:00
abstract::To remain experts in skin care and treatment, every dermatologist must be aware of the evolving role of soft tissue fillers in dermatology. Patients with facial scarring, lipodystrophy, contour abnormalities, and age- and sun-induced rhytids can be successfully treated. A literature review, industry recommendations, a...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2004.09.009
更新日期:2005-04-01 00:00:00
abstract::Rothmund-Thomson syndrome is a rare inherited disorder characterized by poikilodermatous skin changes that appear in infancy. The inheritance is autosomal recessive. Patients exhibit variable features including skeletal abnormalities, juvenile cataracts, and a higher-than-expected incidence of malignancy. This article...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1995-01-01 00:00:00
abstract::The Armed Forces Institute of Pathology (AFIP) is well known for providing expert pathology in many specialties and educational courses for civilian and military personnel. Some of the departments at the AFIP have also developed expertise in various advanced laboratory techniques for diagnosis and research that are ap...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70074-7
更新日期:1999-01-01 00:00:00
abstract::I would like to stress that there seem to be three subpopulations of neural crest-derived melanocytes in the body that can be functionally and morphologically distinguished: the cutaneous melanocytes, which continuously synthesize small melanosomes to be transferred to keratinocytes; the uveal melanocytes, which synth...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1988-04-01 00:00:00
abstract::Photoprotection as it pertains to hair is not a common topic addressed by the dermatologist. Hair is nonliving and requires no protection from ultraviolet (UV) radiation because carcinogenesis of the hair shaft itself is not possible. If hair proteins are altered by sun exposure, damaged hair can be removed and replac...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/j.det.2005.08.006
更新日期:2006-01-01 00:00:00
abstract::Computer hardware refers to the physical electronic and mechanical components of a computer system. These components can be broken down into the central processing unit, memory, storage, terminals, and printers. The function of each of these is described and variations discussed. The hardware needed for communications...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1986-10-01 00:00:00
abstract::AIDS produces profound alterations in normal immunity. Impaired cellular immunity permits new tumor formation as evidenced by the solid-organ transplant literature. The weakened cellular immune system of HIV-infected patients resembles in some ways the iatrogenic immunosuppression in solid-organ transplant recipients....
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2006.06.011
更新日期:2006-10-01 00:00:00
abstract::Bullous disease in children can be confusing clinically and challenging to mange. Five groups of autoimmune bullous disease are discussed with emphasis on unique features in children. Pemphigus (vulgaris, foliaceus, neonatal), pemphigoid (bullous and cicatricial), dermatitis herpetiformis, linear IgA dermatosis, and e...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1993-07-01 00:00:00
abstract::With simple, inexpensive therapy, virtually all venous ulcers heal without the need for hospitalization, skin grafting, growth factors, hyperbaric oxygen, or debilitating bed rest. Although the future promises to yield a greater understanding about the nature of these wounds and ways to treat them, one can benefit the...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1993-10-01 00:00:00
abstract::This article has shown that all the necessary components for successful control of gonorrhea are available. In developed countries, general improvements in economic conditions and advances in treatment and diagnosis have resulted in the lowest incidence rates of gonorrhea ever. Within these countries, however, control...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/s0733-8635(05)70036-x
更新日期:1998-10-01 00:00:00
abstract::Nail psoriasis, melanonychia striata, and onychomycosis are relatively common nail disorders that have generated much research into their pathophysiology and treatment. The authors hope this discussion of the recent therapeutic developments for treating these disorders will not only inform but will also inspire furthe...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70145-5
更新日期:2000-01-01 00:00:00
abstract::Reconstruction of the nose provides many challenges owing to its differing subunits and varied surfaces. In this article, the nasal anatomy, anesthesia, and some of the reconstructive options available to the dermatologic surgeon are reviewed. These reconstructive options are based on the subunit and depth of the defe...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70489-7
更新日期:1998-01-01 00:00:00
abstract::Ultraviolet (UV) radiation contributes to the development of skin cancer through direct and indirect DNA damage, production of reactive oxygen species, and local immunomodulation. The association between UV radiation and skin cancer has raised concern for the risk of carcinogenesis following phototherapy. The photocar...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2019.08.003
更新日期:2020-01-01 00:00:00
abstract::The therapeutic approach to mucous membrane pemphigoid is site specific, with the goal of preserving function for patients with chronic and treatment-resistant disease. The involvement of certain mucosal sites (ie, ocular, laryngeal, esophageal, nasopharyngeal, and anogenital) is high risk and warrants more aggressive...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2011.06.022
更新日期:2011-10-01 00:00:00
abstract::Epidermolysis bullosa (EB) in Mexico continues to be a rare genodermatosis that is still unknown for most of the health care professionals in the country. The spirit of DebRA MEXICO was born in 1994 when the Mexican health care team started to see patients with the main purpose to provide medical care, genetic counsel...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2010.02.014
更新日期:2010-04-01 00:00:00
abstract::Among the different classes and complexities of antiretroviral regimens, maximal viral suppression, sustained durability, increased CD4 count, decreased evolving resistance, and fewer side effects combined with increased compliance resulting in decreased morbidity and mortality remain the goals of therapy. Serial vira...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70314-4
更新日期:2001-10-01 00:00:00
abstract::Pigmentary disorders are common and can be very distressing to patients. There is a need for better, standardized therapies. The authors review the most recent data for topical, systemic, light, and laser treatments for vitiligo, melasma, and postinflammatory hyperpigmentation. There is a paucity of large-scale, well-...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2018.12.008
更新日期:2019-04-01 00:00:00
abstract::The goal of photochemotherapy in psoriasis is to attempt to lower the number of exposures and the total cumulative doses while still maintaining good control of the disease. PUVA has been modified by using better psoralen preparations and more effective light sources, and it also has been combined with other treatment...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1995-10-01 00:00:00
abstract::Treating the underlying pathophysiology of the wound remains of utmost importance. Several new treatment modalities may soon be available as adjunctive treatments. The efficacy of some remains to be established in well-controlled clinical studies. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70414-9
更新日期:1997-01-01 00:00:00
abstract::Nail disorders are difficult to treat and often frustrating both for patients and clinicians. Because of the slow growth rate of the nail plate and the difficulty of getting the drug actives to penetrate the nail tissues, it is usually necessary to wait several months before seeing the results of treatments. This dela...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2014.12.001
更新日期:2015-04-01 00:00:00
abstract::There have been many advances during the past few years relating to the treatment of superficial fungal infections. This article focuses on recent developments, particularly in oral therapy, but in topical therapy as well. First, the newer agents (especially fluconazole, itraconazole, and terbinafine) are reviewed, an...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70337-5
更新日期:1996-01-01 00:00:00
abstract::Reports of fatalities following liposuction have lead to investigations by state medical boards. The risk of complications and fatalities is clearly different for liposuction under local anesthesia and intravenous sedation. Thousands of patients have been treated with true tumescent liposuction as described by dermato...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/s0733-8635(05)70137-6
更新日期:1999-10-01 00:00:00
abstract::Based on the disagreements about the role of atopy in the condition known as atopic dermatitis, it is not surprising that there have been divergent views concerning the appropriate treatment of the disease. A large population of physicians, including most dermatologists and some allergists, believe that the fundamenta...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1986-01-01 00:00:00
abstract::A hypothesis is proposed for the etiopathogenesis of some cases of Hodgkin's disease, Sezary's syndrome, and related disorders that compose the cutaneous T-cell lymphoma group. This new model, termed the thymus bypass model, is discussed in detail in this article. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1994-04-01 00:00:00
abstract::In the same way that it often is necessary to perform chemical and biological analysis of skin and body fluids in the management of skin disease, it may be necessary to analyze the chemical environment. Some analyses, such as those for nickel, chromate, and formaldehyde, require only simple tests. Others require compl...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00