Tips to treat the 5 most common nail disorders: brittle nails, onycholysis, paronychia, psoriasis, onychomycosis.

abstract：:Atopic dermatitis is associated with significant patient burden, with impacts from symptoms and visible physical manifestations of the disease. Consequences include detrimental effects on quality of life (QoL), sleep, self-esteem, interpersonal relationships, participation in leisure and sports, and attendance or perf...

journal_title：Dermatologic clinics

authors： Sibbald C,Drucker AM

更新日期：2017-07-01 00:00:00

abstract：:Human papillomaviruses are a heterogeneous group of DNA tumor viruses associated with hyperplastic (warts, condylomata), dysplastic (CIN and VIN), and malignant lesions (carcinomas) of squamous epithelium. Each HPV type is preferentially associated with specific clinical lesions and has an anatomic site preference for...

journal_title：Dermatologic clinics

authors： Jenson AB,Kurman RJ,Lancaster WD

更新日期：1991-04-01 00:00:00

abstract：:A hypothesis is proposed for the etiopathogenesis of some cases of Hodgkin's disease, Sezary's syndrome, and related disorders that compose the cutaneous T-cell lymphoma group. This new model, termed the thymus bypass model, is discussed in detail in this article. ...

journal_title：Dermatologic clinics

authors： Lambert WC

更新日期：1994-04-01 00:00:00

abstract：:Chronic itch is a clinically challenging yet scientifically remarkable and complex process. Increasing understanding of the pathophysiology of chronic itch is leading to targeted therapeutic approaches that are now dramatically improving quality of life. This improvement will accelerate as the tools of basic and clini...

journal_title：Dermatologic clinics

authors： Lerner EA

更新日期：2018-07-01 00:00:00

abstract：:Alopecia areata (AA) is a recurrent autoimmune type of hair loss that affects about 5.3 million people in the United States alone. Despite being the most prevalent autoimmune disease, the molecular and cellular mechanisms underlying this complex disease are still poorly understood, and rational treatments are lacking....

journal_title：Dermatologic clinics

authors： Jabbari A,Petukhova L,Cabral RM,Clynes R,Christiano AM

更新日期：2013-01-01 00:00:00

abstract：:Since its discovery, the understanding of the roles for TNF-alpha in human biology and disease has grown. Receptors for TNF are found on virtually all cell types, and many physiologic processes seem to be altered by TNF-alpha. The understanding of how TNF-alpha is involved in the pathophysiology of diseases, such as i...

journal_title：Dermatologic clinics

authors： LaDuca JR,Gaspari AA

更新日期：2001-10-01 00:00:00

abstract：:The term pyoderma encompasses a variety of distinct entities including impetigo (bullous and nonbullous), erysipelas, cellulitis, folliculitis, and staphylococcal scalded skin syndrome. Treatment of pyodermas centers around wound care and appropriate antibiotic selection. Triphenylmethane dyes, such as gentian violet,...

journal_title：Dermatologic clinics

authors： Berrios RL,Arbiser JL

更新日期：2011-01-01 00:00:00

abstract：:Skin cancer is reaching epidemic levels in the United States. Recent advances in the understanding of the pathophysiology of melanoma have allowed improved risk stratification in the revised American Joint Committee on Cancer (AJCC) criteria, new tests to capture patients at higher risk than their stage may indicate, ...

journal_title：Dermatologic clinics

authors： Tracey EH,Vij A

更新日期：2019-01-01 00:00:00

abstract：:The excessive sweating of hyperhidrosis creates profound psychosocial, professional, and financial burdens on the individual sufferer; it contributes to impaired self-worth and self-efficacy, decreased satisfaction in all relationships, avoidance of specific careers, and increased expenditures on everything from cloth...

journal_title：Dermatologic clinics

authors： Pieretti LJ

更新日期：2014-10-01 00:00:00

abstract：:Multiple strategies are required to combat the increasing incidence and mortality of cutaneous melanoma. Major questions about melanoma and skin cancer are reviewed, with particular attention to education and early detection. ...

journal_title：Dermatologic clinics

authors： Koh HK,Geller AC,Miller DR,Lew RA

更新日期：1995-07-01 00:00:00

abstract：:Psoriasis vulgaris is a chronic inflammatory skin disease that results from the complex interplay between keratinocytes, dendritic cells, and T cells. Keratinocytes trigger innate and adaptive immune responses. Dermal myeloid dendritic cells regulate T cell activation and production of cytokines and chemokines that am...

journal_title：Dermatologic clinics

authors： Kim J,Krueger JG

更新日期：2015-01-01 00:00:00

abstract：:Cutaneous B-cell lymphomas represent a heterogeneous group of entities which show variation in histology, immunophenotype, and in prognosis. In the current review the morphologic spectrum of cutaneous B-cell lymphomas comprising primary and secondary cutaneous B-cell lymphomas is discussed according to the REAL classi...

journal_title：Dermatologic clinics

authors： Sander CA,Flaig MJ

更新日期：1999-07-01 00:00:00

abstract：:Among the different classes and complexities of antiretroviral regimens, maximal viral suppression, sustained durability, increased CD4 count, decreased evolving resistance, and fewer side effects combined with increased compliance resulting in decreased morbidity and mortality remain the goals of therapy. Serial vira...

journal_title：Dermatologic clinics

authors： Carrasco DA,Tyring SK

更新日期：2001-10-01 00:00:00

abstract：:The recent progress made in understanding the normal biology and biochemistry of the extracellular matrix of human skin has allowed us to identify several different levels at which errors could be introduced into the structure and metabolism of collagen or elastin, the two major fibrillar components of the dermis. Cur...

journal_title：Dermatologic clinics

authors： Uitto J,Shamban A

更新日期：1987-01-01 00:00:00

abstract：:The umbrella term psoriasis is now understood to incorporate several distinct phenotypes or endotypes along the disease spectrum that in turn will dictate different therapies. A stratified medicine approach to psoriasis using this clinical information coupled with pharmacogenomic and immunologic data will become more ...

journal_title：Dermatologic clinics

authors： Menter MA,Griffiths CE

更新日期：2015-01-01 00:00:00

abstract：:Stress is an abnormal or extreme adjustment in the physiology of an animal to cope with adverse effects of its environment and management. The adverse effect is designated the stressor. In this article, the authors try to focus on the main types of host factors that can influence stress (genetics, perception) and on t...

journal_title：Dermatologic clinics

authors： Panconesi E,Hautmann G

更新日期：1996-07-01 00:00:00

abstract：:The craniofacial and oral manifestations of the different epidermolysis bullosa (EB) types vary markedly in character and severity depending largely on the EB type. The tissues affected and the phenotypes displayed are closely related to the specific abnormal or absent proteins resulting from the causative genetic mut...

journal_title：Dermatologic clinics

authors： Wright JT

更新日期：2010-01-01 00:00:00

abstract：:Objectively evaluating disease activity in autoimmune bullous disease (AIBD) is important in terms of the clinical assessment of patients and as an outcome measure for clinical trials. Measures need to be general enough to capture the issues specific to each of the bullous dermatoses but specific enough to capture any...

journal_title：Dermatologic clinics

authors： Sebaratnam DF,Murrell DF

更新日期：2011-07-01 00:00:00

abstract：:Kaposi sarcoma (KS) is an angioproliferative mesenchymal neoplasm caused by Kaposi sarcoma-related herpesvirus. This review outlines our current understanding of the epidemiology, pathogenesis, clinical presentation, and staging for this disease. Recent research has informed a more comprehensive understanding of the e...

journal_title：Dermatologic clinics

authors： Etemad SA,Dewan AK

更新日期：2019-10-01 00:00:00

abstract：:Hair transplantation has developed into a refined art in the past 30 years. Refined techniques and instruments, appreciation of properly placed hairlines, better methods of harvesting donor grafts, and better cutting materials in punches have significantly improved results in one of the most frequently performed cosme...

journal_title：Dermatologic clinics

authors： Knowles WR

更新日期：1987-07-01 00:00:00

abstract：:The development and use of various laser systems for the treatment of carcinomas of the skin constitute a relatively new therapeutic approach. Because the skin is a readily accessible organ, it is an excellent site at which to attempt different therapeutic modalities. What is truly astounding has been the development ...

journal_title：Dermatologic clinics

authors： Geronemus R,Ashinoff R

更新日期：1991-10-01 00:00:00

abstract：:The success of the Mohs procedure depends on the reliability of each step in the technique. Pitfalls in histologic preparation of the tissue specimens may occur during debulking, excising, orienting, creating the map, sectioning, inking, tissue flattening and freezing, cutting, slide fixation, staining, and mapping th...

journal_title：Dermatologic clinics

authors： Bouzari N,Olbricht S

更新日期：2011-04-01 00:00:00

abstract：:Laser skin surgery is not without risk and some degree of downtime in most situations. Patient satisfaction is key to the perceived success of the procedure. Therefore, the physician must fully explain all risks, potential complications, and expected morbidity associated with any laser treatment to be performed. Altho...

journal_title：Dermatologic clinics

authors： McBurney EI

更新日期：2002-01-01 00:00:00

abstract：:Excising cancer in successive layers and examining the entire underside of each layer in the microscope by the systematic use of frozen sections ensure eradication of the neoplasm, including its "silent" outgrowths, and this is accomplished with the maximal sparing of normal tissue. Fresh-tissue micrographic surgery i...

journal_title：Dermatologic clinics

authors： Mohs FE

更新日期：1989-10-01 00:00:00

abstract：:Chronic telogen effluvium is not uncommon. It is a form of diffuse hair loss affecting the entire scalp for which no obvious cause can be found. It usually affects women of 30 to 60 years of age who generally have a full head of hair prior to the onset of shedding. The onset is usually abrupt, with or without a recogn...

journal_title：Dermatologic clinics

authors： Whiting DA

更新日期：1996-10-01 00:00:00

abstract：:Vitiligo, an acquired disease of depigmentation, affects millions worldwide. The psychosocial and health-related quality of life (HRQL) impact of the disease varies based on several parameters, including country of origin, skin type, gender, age, marital status, and involved body site. Many instruments, both dermatolo...

journal_title：Dermatologic clinics

authors： Bhandarkar SS,Kundu RV

更新日期：2012-04-01 00:00:00

abstract：:This article contains a potpurri of surgically related stratagems, alternative techniques, and philosophies. These surgical pearls have been selected for their simplicity, usefulness, and applicability. ...

journal_title：Dermatologic clinics

authors： Salasche SJ,Winton GB,Adnot J

更新日期：1989-01-01 00:00:00

abstract：:The general goals of medical management of vitiligo are to repigment vitiliginous areas of skin and to stabilize the progression of depigmentation. However, for some patients with vitiligo affecting extensive body surface areas who are unresponsive to repigmentation therapies, depigmentation of the remaining normal sk...

journal_title：Dermatologic clinics

authors： Grimes PE,Nashawati R

更新日期：2017-04-01 00:00:00

abstract：:KS remains a challenge to clinicians and investigators more than a century after its initial description. Debate continues as to the cell of origin, as well as whether or not it is a true cancer. KS appears to be an opportunistic neoplasm, which in its earliest phase retains some features of a benign hyperproliferativ...

journal_title：Dermatologic clinics

authors： Myskowski PL,Ahkami R

更新日期：1997-01-01 00:00:00

abstract：:If one looks at the development of most drugs, it becomes evident that an extended period of time is necessary before the proper use and full range of activities of the drug in treating human disease become apparent. In many cases, initial treatment failures are due to faulty expectations as well as inadequate dosing ...

journal_title：Dermatologic clinics

authors： Falanga V

更新日期：1993-10-01 00:00:00