Abstract:
:The therapeutic approach to mucous membrane pemphigoid is site specific, with the goal of preserving function for patients with chronic and treatment-resistant disease. The involvement of certain mucosal sites (ie, ocular, laryngeal, esophageal, nasopharyngeal, and anogenital) is high risk and warrants more aggressive intervention. Control of the disease must be balanced with minimizing the sequelae of long-term exposure to systemic glucocorticosteroids and/or other immunosuppressives. Timely interventions and multidisciplinary management are essential in preventing disability.
journal_name
Dermatol Clinjournal_title
Dermatologic clinicsauthors
Kourosh AS,Yancey KBdoi
10.1016/j.det.2011.06.022subject
Has Abstractpub_date
2011-10-01 00:00:00pages
637-41issue
4eissn
0733-8635issn
1558-0520pii
S0733-8635(11)00130-6journal_volume
29pub_type
杂志文章,评审abstract::Although clinical trials for new drugs are often limited in children because of safety concerns or restrictions, new therapies or novel strategies with old drugs have recently expanded dermatologic armamentarium for pediatric patients. Oral propranolol is currently the first choice in the treatment of alarming infanti...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/j.det.2010.03.005
更新日期:2010-07-01 00:00:00
abstract::Although new technologies are becoming available to aid in diagnosis, the skin biopsy continues to be the fundamental tool of the dermatologist to evaluate the nature of a pigmented lesion. There are 3 major techniques for the biopsy of a pigmented lesion: shave biopsy, punch/incisional biopsy, and excisional biopsy. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2012.04.013
更新日期:2012-07-01 00:00:00
abstract::The recent progress made in understanding the normal biology and biochemistry of the extracellular matrix of human skin has allowed us to identify several different levels at which errors could be introduced into the structure and metabolism of collagen or elastin, the two major fibrillar components of the dermis. Cur...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1987-01-01 00:00:00
abstract::Patients with urogenital complaints are frequently encountered by family practitioners, gynecologists, and dermatologists. This review article provides practical information regarding normal anatomy and embryology of the vulva, followed by a summary of procedural techniques. The new classifications of vulvar inflammat...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2010.07.005
更新日期:2010-10-01 00:00:00
abstract::This article has shown that all the necessary components for successful control of gonorrhea are available. In developed countries, general improvements in economic conditions and advances in treatment and diagnosis have resulted in the lowest incidence rates of gonorrhea ever. Within these countries, however, control...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/s0733-8635(05)70036-x
更新日期:1998-10-01 00:00:00
abstract::Hand dermatitis is a common disease of the skin resulting in significantly decreased quality of life. Allergic contact dermatitis is a frequent cause of hand dermatitis. Recent studies have revealed that biocides used as preservatives are frequent allergens affecting the hands. This article reviews common biocides imp...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2009.05.007
更新日期:2009-07-01 00:00:00
abstract::Hidradenitis suppurativa (HS) is a chronic, inflammatory, scarring condition involving the intertriginous skin of the axillary, inguinal, inframammary, genital, and perineal areas of the body. It is also referred to as acne inversa and Verneuil disease. Follicular occlusion is the primary event in HS. It is now accept...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2010.07.003
更新日期:2010-10-01 00:00:00
abstract::Discolorations of the skin, such as vitiligo, were recognized thousands of years ago. White spots caused by vitiligo and other disorders have caused significant social opprobrium to those disfigured by these pigmentary disorders, throughout history and still in the present day. Treatments have been desperately sought ...
journal_title:Dermatologic clinics
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.det.2016.11.001
更新日期:2017-04-01 00:00:00
abstract::This article reviews the recent dermatopathology literature involving nonmelanocytic neoplasia, with a focus on important work done over the last 5 years. The discussion includes advances in the understanding of Merkel cell carcinoma pathogenesis and prognosis; changes in the seventh edition of the American Joint Comm...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2012.06.009
更新日期:2012-10-01 00:00:00
abstract::The term pyoderma encompasses a variety of distinct entities including impetigo (bullous and nonbullous), erysipelas, cellulitis, folliculitis, and staphylococcal scalded skin syndrome. Treatment of pyodermas centers around wound care and appropriate antibiotic selection. Triphenylmethane dyes, such as gentian violet,...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2010.08.009
更新日期:2011-01-01 00:00:00
abstract::For both NF and Albright's syndrome, the pathogenetic relationships between the various elements of the respective syndromes remain a mystery, and the importance of nontumorous endocrine abnormalities in neurofibromatosis has, in my opinion, been overstated. Nonetheless, the parallel between the two disorders is strik...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1987-01-01 00:00:00
abstract::This article is a tribute to clinician Henry M. Lewis. The author shares practical therapeutic pearls developed and used over the years by Dr. Lewis. ...
journal_title:Dermatologic clinics
pub_type: 传,历史文章,杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::In this article, vulvar anatomy and histology are reviewed, and nonneoplastic and neoplastic epithelial disorders are presented. Included are lichen sclerosus, squamous cell hyperplasia, vulvar intraepithelial neoplasia, vulvar Paget's disease, and squamous cell carcinoma. Current terminology, tumor measurements, and ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1992-04-01 00:00:00
abstract::Dermatopathology (DP) education is critical to the comprehensive training of dermatology and pathology residents and to the accurate diagnosis and management of cutaneous disease. DP has seen tremendous growth, and its success depends on our ability to effectively educate future leaders, teachers, and researchers who ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2012.06.003
更新日期:2012-10-01 00:00:00
abstract::Current aesthetic dermatology rejuvenation options offer minimally invasive, more affordable alternatives to traditional cosmetic surgery. Chemical peels and laser resurfacing can significantly improve the appearance of the skin and stimulate neocollagenesis; botulinum toxin reduces the appearance of dynamic facial li...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2009.08.013
更新日期:2009-10-01 00:00:00
abstract::Countries in the so-called "Western" world, especially in Europe, witnessed a dramatic change in ethnic backgrounds of their populations starting in the last decennia of the last century. This had repercussions on various aspects of our society, including medical practice. In dermatology for instance, pigmentary disor...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2007.04.005
更新日期:2007-07-01 00:00:00
abstract::Cutaneous B-cell lymphomas represent a heterogeneous group of entities which show variation in histology, immunophenotype, and in prognosis. In the current review the morphologic spectrum of cutaneous B-cell lymphomas comprising primary and secondary cutaneous B-cell lymphomas is discussed according to the REAL classi...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70109-1
更新日期:1999-07-01 00:00:00
abstract::Medical spas are the fasting growing segment of the 15-billion dollar spa industry. Although medical spas have been in existence since ancient times to treat a wide variety of ailments such as gout, arthritis, and diabetes, our modern concept of the medical spa combines relaxation with medical rejuvenative procedures....
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2008.03.003
更新日期:2008-07-01 00:00:00
abstract::The author has attempted to analyze the physical characteristics of liposuction surgery. By categorizing liposuction surgery into various types of procedures, the dermatologic surgeon can describe and elucidate the manner of performing liposuction in each anatomic region. The procedures for fat tunneling and harvestin...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract::Many older individuals use products and procedures to conceal or delay the signs of aging. For most, this provides a helpful ego boost, but some suffer from pathologies such as eating disorders and body dysmorphic disorder. The impact of aging skin may include social anxiety and social isolation. Poor self-image is as...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2005.05.012
更新日期:2005-10-01 00:00:00
abstract::Atopic dermatitis is associated with significant patient burden, with impacts from symptoms and visible physical manifestations of the disease. Consequences include detrimental effects on quality of life (QoL), sleep, self-esteem, interpersonal relationships, participation in leisure and sports, and attendance or perf...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2017.02.004
更新日期:2017-07-01 00:00:00
abstract::The work described in this article reveals a remarkable lack of consensus as to whether percutaneous absorption changes as humans grow older. The data that have been recorded point to possible significant alterations in the barrier function with age. The importance of these observations with respect to dermatopharmaco...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1986-07-01 00:00:00
abstract::The systematic evaluation of photosensitive patients involves a comprehensive history, physical examination, phototesting, and, if necessary, photopatch testing and laboratory evaluation. Polymorphous light eruption, chronic actinic dermatitis, solar urticaria, and photosensitivity secondary to systemic medications ar...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2014.03.006
更新日期:2014-07-01 00:00:00
abstract::Reports of fatalities following liposuction have lead to investigations by state medical boards. The risk of complications and fatalities is clearly different for liposuction under local anesthesia and intravenous sedation. Thousands of patients have been treated with true tumescent liposuction as described by dermato...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/s0733-8635(05)70137-6
更新日期:1999-10-01 00:00:00
abstract::This brief survey has, it is hoped, helped to ease some of the anxiety associated with the management of complex autoimmune skin disorders. The main points to remember are that there are numerous therapeutic options for each disease. I like to think of this method of therapeutics as 'informed trial and error.' One doe...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70479-4
更新日期:1997-10-01 00:00:00
abstract::Infections by VZV, the virus that causes chickenpox and herpes zoster, usually are diagnosed by the classic clinical presentations. In immunocompromised patients, however, the atypical presentation can make the diagnosis more challenging. Although varicella typically follows an uncomplicated course in children, adults...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(01)00012-2
更新日期:2002-04-01 00:00:00
abstract::Adverse reactions to medications are common and may have a variety of clinical presentations in the oral cavity. Targeted therapies and new biologic agents have revolutionized the treatment of cancers, autoimmune diseases, and inflammatory and rheumatologic diseases but have also been associated with adverse events in...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2020.05.012
更新日期:2020-10-01 00:00:00
abstract::Traditional chemotherapies, interleukins, phosphorylase inhibitors, and proteasome inhibitors are important therapies available to patients with cutaneous T-cell lymphoma (CTCL). Traditional chemotherapies, both in combination and as single agents, are commonly used in relapsed, refractory CTCLs that behave in an aggr...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2015.05.012
更新日期:2015-10-01 00:00:00
abstract::The carcinoid syndrome and its clinical manifestations have been discussed. The standard laboratory test for making that diagnosis is urinary 5-HIAA levels but newer, more sensitive tests may also be available. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
abstract::This article presents solutions to difficult surgical repair problems. Solutions for the repair of defects in the ear (in this case the ear lobule) and upper lip are discussed. A solution is also provided for an exasperating problem that arises when cheek and neck lifts are done. An aid for the design of cutaneous fla...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00