Abstract：
:Adverse reactions to medications are common and may have a variety of clinical presentations in the oral cavity. Targeted therapies and new biologic agents have revolutionized the treatment of cancers, autoimmune diseases, and inflammatory and rheumatologic diseases but have also been associated with adverse events in the oral cavity. This review describes the most common clinical presentations of oral mucosal reactions to medications, namely hyposalivation, lichenoid reactions, ulcers, bullous disorders, pigmentation, fibrovascular hyperplasia, reactive keratosis, dysesthesia, osteonecrosis, infection, angioedema, and malignancy.
journal_name
Dermatol Clinjournal_title
Dermatologic clinicsauthors
Yuan A,Woo SBdoi
10.1016/j.det.2020.05.012subject
Has Abstractpub_date
2020-10-01 00:00:00pages
523-533issue
4eissn
0733-8635issn
1558-0520pii
S0733-8635(20)30046-2journal_volume
38pub_type
杂志文章,评审abstract：:Psoriasis vulgaris is a chronic inflammatory skin disease that results from the complex interplay between keratinocytes, dendritic cells, and T cells. Keratinocytes trigger innate and adaptive immune responses. Dermal myeloid dendritic cells regulate T cell activation and production of cytokines and chemokines that am...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2014.09.002
更新日期：2015-01-01 00:00:00
abstract：:Contact dermatitis in the United States poses a significant public health concern. This article provides a definition of contact dermatitis and its associated risk factors. The authors discuss the epidemiology of occupational contact dermatitis including its incidence and prevalence, and describe how estimates are cal...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2011.08.004
更新日期：2012-01-01 00:00:00
abstract：:Medical spas are the fasting growing segment of the 15-billion dollar spa industry. Although medical spas have been in existence since ancient times to treat a wide variety of ailments such as gout, arthritis, and diabetes, our modern concept of the medical spa combines relaxation with medical rejuvenative procedures....
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2008.03.003
更新日期：2008-07-01 00:00:00
abstract：:Surgery for skin cancer is a major part of clinical dermatology, and the largest single component of dermatologic surgery practice. In general, residency training in dermatology provides comprehensive training in the theory and practice of skin cancer surgery. Practicing dermatologists are similarly expert in this are...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2016.02.012
更新日期：2016-07-01 00:00:00
abstract：:Excising cancer in successive layers and examining the entire underside of each layer in the microscope by the systematic use of frozen sections ensure eradication of the neoplasm, including its "silent" outgrowths, and this is accomplished with the maximal sparing of normal tissue. Fresh-tissue micrographic surgery i...
journal_title：Dermatologic clinics
pub_type： 历史文章,杂志文章
doi：
更新日期：1989-10-01 00:00:00
abstract：:The technical advances of the last century changed the understanding of the science of cutaneous physiology and pathology and the role of the dermatologist. The major challenges the international dermatologic community faces today are the lack of a common, logical, and accepted language within the specialty; long-acce...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2007.11.002
更新日期：2008-04-01 00:00:00
abstract：:Although trichoscopy has only recently been introduced in the assessment of hair and scalp disorders, it is already considered an essential diagnostic tool by many experts in the field. This article discusses topics that are often a source of doubt among clinicians, and tips that may help dermatologists better perform...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2018.05.008
更新日期：2018-10-01 00:00:00
abstract：:Granuloma formation is usually regarded as a means of defending the host from persistent irritants of either exogenous or endogenous origin. Noninfectious granulomatous disorders of the skin encompass a challenging group of diseases owing to their clinical and histologic overlap. Drug reactions characterized by a gran...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2015.03.015
更新日期：2015-07-01 00:00:00
abstract：:This article provides a protocol for the systematic approach to the technique of Mohs micrographic surgery. Each step, from tumor excision and tissue mapping, to specimen processing and histologic interpretation, through wound closure and postoperative management, is covered. The advantages of Mohs surgery over other ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2011.02.002
更新日期：2011-04-01 00:00:00
abstract：:Patient-centered care in dermatologic surgery emphasizes addressing the preferences, values, and concerns of the surgical patient in an effort to improve the overall experience. Impediments affecting the delivery of Mohs micrographic surgical treatment of skin cancers are present throughout the perioperative period. D...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2019.03.006
更新日期：2019-07-01 00:00:00
abstract：:Native Americans have a rich and complex heritage and culture. Although the genetic pool has changed with increasing integration with other Americans with different ancestry, there are important conditions that are unique to Native Americans, the most prominent example being actinic prurigo. The scientific literature ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(03)00076-7
更新日期：2003-10-01 00:00:00
abstract：:Nail psoriasis, melanonychia striata, and onychomycosis are relatively common nail disorders that have generated much research into their pathophysiology and treatment. The authors hope this discussion of the recent therapeutic developments for treating these disorders will not only inform but will also inspire furthe...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70145-5
更新日期：2000-01-01 00:00:00
abstract：:Tetracyclines are known to exhibit multiple significant anti-inflammatory actions. This article describes the mechanisms of this anti-inflammatory activity, such as inhibition of chemotaxis, granuloma formation, and protease. The article also discusses the effectiveness of tetracyclines in treating such diseases as ac...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2007.01.012
更新日期：2007-04-01 00:00:00
abstract：:This brief survey has, it is hoped, helped to ease some of the anxiety associated with the management of complex autoimmune skin disorders. The main points to remember are that there are numerous therapeutic options for each disease. I like to think of this method of therapeutics as 'informed trial and error.' One doe...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70479-4
更新日期：1997-10-01 00:00:00
abstract：:In all forms of epidermolysis bullosa (EB), skin fragility may result in bacterial colonization or infection, particularly in the more severe forms where wounds may be multiple and long-standing. A balance exists between a wound's bacterial load and the host defenses, such that there is a spectrum from simple contamin...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2010.01.004
更新日期：2010-04-01 00:00:00
abstract：:Histoplasmosis is caused by Histoplasma capsulatum, a dimorphic fungus. Because histoplasmosis is usually a self-limited disease in the majority of cases, treatment often is not needed in the normal host. However, severe cases of acute pulmonary histoplasmosis require therapy. Amphotericin B is considered the treatmen...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1989-04-01 00:00:00
abstract：:The development and use of various laser systems for the treatment of carcinomas of the skin constitute a relatively new therapeutic approach. Because the skin is a readily accessible organ, it is an excellent site at which to attempt different therapeutic modalities. What is truly astounding has been the development ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1991-10-01 00:00:00
abstract：:The terms "palisaded neutrophilic and granulomatous dermatitis," "interstitial granulomatous dermatitis," and the subset "interstitial granulomatous drug reaction" are a source of confusion. There exists substantial overlap among the entities with few strict distinguishing features. We review the literature and highli...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2015.03.005
更新日期：2015-07-01 00:00:00
abstract：:This article describes major screening studies of the past two decades, discusses the evidence-based screening recommendations, highlights the need to screen high-risk and previously unscreened populations, and concludes with suggestions for risk assessment and physician-nurse training in the skin cancer examination. ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(02)00034-7
更新日期：2002-10-01 00:00:00
abstract：:Reports of fatalities following liposuction have lead to investigations by state medical boards. The risk of complications and fatalities is clearly different for liposuction under local anesthesia and intravenous sedation. Thousands of patients have been treated with true tumescent liposuction as described by dermato...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：10.1016/s0733-8635(05)70137-6
更新日期：1999-10-01 00:00:00
abstract：:The systematic evaluation of photosensitive patients involves a comprehensive history, physical examination, phototesting, and, if necessary, photopatch testing and laboratory evaluation. Polymorphous light eruption, chronic actinic dermatitis, solar urticaria, and photosensitivity secondary to systemic medications ar...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2014.03.006
更新日期：2014-07-01 00:00:00
abstract：:The skin and the nervous system develop side by side in the fetus and remain intimately interconnected and interactive throughout life. Because of the skin-nervous system interactions, there is a significant psychosomatic or behavioral component to many dermatologic conditions. This permits complementary nonpharmacolo...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2005.05.011
更新日期：2005-10-01 00:00:00
abstract：:Antimalarial compounds have been demonstrated to be both safe and efficacious in the treatment of lupus erythematosus as well as several other dermatologic conditions. It is imperative, however, that physicians familiarize themselves with the potential complications associated with the use of these agents. Furthermore...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1992-07-01 00:00:00
abstract：:Computer hardware refers to the physical electronic and mechanical components of a computer system. These components can be broken down into the central processing unit, memory, storage, terminals, and printers. The function of each of these is described and variations discussed. The hardware needed for communications...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：
更新日期：1986-10-01 00:00:00
abstract：:Pediatric allergic contact dermatitis (Ped-ACD) is an increasingly recognized highly prevalent skin disease that has a significant impact on the quality of life of patients and their families. Accurate and appropriate patch testing is vital to diagnosing Ped-ACD. This requires knowledge of the most common allergens in...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2020.02.003
更新日期：2020-07-01 00:00:00
abstract：:Melanoma vaccines represent a novel and potentially effective method of slowing the progression of melanoma. This article discusses the importance in the design of vaccines for melanoma, the relative advantages and disadvantages of this approach, and summarizes the results of the most important clinical trials conduct...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70009-7
更新日期：1998-04-01 00:00:00
abstract：:Advances in laser technology now permit the physician to provide an effective form of treatment for a large variety of cutaneous disorders for which no previous therapy or only poor forms of therapy previously existed. Additional refinements in both laser instruments and treatment techniques are certain to have a prof...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：
更新日期：1987-04-01 00:00:00
abstract：:Hair transplantation has developed into a refined art in the past 30 years. Refined techniques and instruments, appreciation of properly placed hairlines, better methods of harvesting donor grafts, and better cutting materials in punches have significantly improved results in one of the most frequently performed cosme...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1987-07-01 00:00:00
abstract：:Many genodermatoses have distinct oral features that may help identify or confirm a genetic diagnosis. Oral features of the disorders described here are summarized in Table 1. These conditions provide clear examples of rapid progress in the field of genetic technology relevant to patient care. Less than a decade ago, ...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：10.1016/s0733-8635(02)00082-7
更新日期：2003-01-01 00:00:00
abstract：:Dermatopathology (DP) education is critical to the comprehensive training of dermatology and pathology residents and to the accurate diagnosis and management of cutaneous disease. DP has seen tremendous growth, and its success depends on our ability to effectively educate future leaders, teachers, and researchers who ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2012.06.003
更新日期：2012-10-01 00:00:00
