Abstract：
:Excising cancer in successive layers and examining the entire underside of each layer in the microscope by the systematic use of frozen sections ensure eradication of the neoplasm, including its "silent" outgrowths, and this is accomplished with the maximal sparing of normal tissue. Fresh-tissue micrographic surgery is used for most cancers, but the fixed-tissue technique is safer for melanomas because all incisions are made through fixed (killed) tissues, avoiding the danger of disseminating highly transplantable melanoma cells from transecting silent outgrowths or clinically invisible satellites. Although the essential concept was very simple, more than a half century of continuing development was required to bring the method to its present status; further progress is an exciting prospect.
journal_name
Dermatol Clinjournal_title
Dermatologic clinicsauthors
Mohs FEsubject
Has Abstractpub_date
1989-10-01 00:00:00pages
609-11issue
4eissn
0733-8635issn
1558-0520journal_volume
7pub_type
历史文章,杂志文章abstract：:The only spiders of real medical importance to humans in the United States are the Loxosceles and Latrodectus species, primarily the brown recluse and the black window, respectively. These spiders bite humans only when trapped or crushed against the skin. Severe brown recluse spider bites produce dermonecrosis within ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1990-04-01 00:00:00
abstract：:Patient-centered care in dermatologic surgery emphasizes addressing the preferences, values, and concerns of the surgical patient in an effort to improve the overall experience. Impediments affecting the delivery of Mohs micrographic surgical treatment of skin cancers are present throughout the perioperative period. D...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2019.03.006
更新日期：2019-07-01 00:00:00
abstract：:Black patients who desire cosmetic surgery have not had many treatment options or services available to them. At this time, the requests for specific cosmetic surgical procedures by black patients have far exceeded the number of cosmetic surgeons able to meet their needs. A surgeon who calls himself or herself a cosme...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1988-07-01 00:00:00
abstract：:The author reviews published papers on human hair growth in nude mice. There is evidence from various sources indicating that grafting of human scalp onto nude mice does not modify significantly morphogenesis, hair follicle structure and function, and composition of the newly grown hair fiber. On the basis of personal...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70388-0
更新日期：1996-10-01 00:00:00
abstract：:The basis of in-office evaluation of leg vascular disease involves Doppler ultrasound to estimate flow in arteries and veins. Arterial evaluation localizes sites of obstruction by segmental pressures obtained by Doppler signal assessment using pressure cuffs. Ankle compared with brachial arterial pressure is the most ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1994-01-01 00:00:00
abstract：:The author has attempted to analyze the physical characteristics of liposuction surgery. By categorizing liposuction surgery into various types of procedures, the dermatologic surgeon can describe and elucidate the manner of performing liposuction in each anatomic region. The procedures for fat tunneling and harvestin...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：
更新日期：1990-07-01 00:00:00
abstract：:Chromoblastomycosis is a chronic cutaneous infection due to several varieties of pigmented fungi. Diagnosis is straightforward and based on clinical and microscopic findings. Despite the protracted course of the disease, dissemination of the infection is rare. New insights into the pathophysiology may permit a closer ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70327-2
更新日期：1996-01-01 00:00:00
abstract：:Porosity, elasticity, and texture influence the hair's ability to be changed. The types of color--temporary, gradual, natural, semipermanent, and permanent--depend upon the size of the "coloring" molecule to determine whether they penetrate the cortex (permanent) or precipitate on the cuticle. Different types of hair-...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：
更新日期：1987-07-01 00:00:00
abstract：:We have limited the scope of this article to those disorders that have already been successfully diagnosed or excluded in utero. We currently have the potential to diagnose a number of others for which the opportunity has not yet arisen. If a biochemical, morphologic, chromosomal, or DNA alteration is known for a spec...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1987-01-01 00:00:00
abstract：:There is a dearth of information on psoriasis in the tropics. Psoriasis occurs more frequently in northern geographic regions than in tropical climates. Its prevalence varies not only within the ethnic groups of a country but from country to country. A review of published studies on the natural history of psoriasis in...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1994-10-01 00:00:00
abstract：:In this article, the authors summarize the published literature on the reliability and accuracy of teledermatology. The first section reports on the diagnostic reliability of teledermatology compared with face-to-face clinic consultation. In the second section, the authors report on the "intragroup" diagnostic agreeme...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2008.11.012
更新日期：2009-04-01 00:00:00
abstract：:Nasal reconstruction can be challenging due to the complex nature of multiple cosmetic units and functional considerations. This article discusses single- and two-staged melolabial flap repairs for nasal reconstruction following removal of skin cancers. ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2004.08.003
更新日期：2005-01-01 00:00:00
abstract：:The exact epidemiology of autoimmune bullous disorders in Australia is unknown. This article describes the establishment of a registry and support group to serve patients with these disorders. The registry aids research in Australia by providing epidemiologic data and maintaining an up-to-date database with patient co...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：10.1016/j.det.2011.07.002
更新日期：2011-10-01 00:00:00
abstract：:Although the Mohs technique is most often applied to moderate and large lesions, with appropriate modifications it can also be applied to massive lesions. Reconstructive procedures after resection of large defects are also discussed. ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1989-10-01 00:00:00
abstract：:Normal and malignant pigment cells are known targets for many hormones. Besides alpha-melanocyte-stimulating hormone and the steroidal hormones estrogen, testosterone, and glucocorticoids, factors produced by other epidermal cells can affect melanization and proliferation of pigment cells. Among those factors are the ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1988-04-01 00:00:00
abstract：:The term viral hemorrhagic fever refers to a clinical syndrome characterized by acute onset of fever accompanied by nonspecific findings of malaise, prostration, diarrhea,and headache. Patients frequently show signs of increased vascular permeability, and many develop bleeding diatheses. The hemorrhagic fever viruses ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2004.03.003
更新日期：2004-07-01 00:00:00
abstract：:Skin cancer is reaching epidemic levels in the United States. Recent advances in the understanding of the pathophysiology of melanoma have allowed improved risk stratification in the revised American Joint Committee on Cancer (AJCC) criteria, new tests to capture patients at higher risk than their stage may indicate, ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2018.08.003
更新日期：2019-01-01 00:00:00
abstract：:There have been many advances during the past few years relating to the treatment of superficial fungal infections. This article focuses on recent developments, particularly in oral therapy, but in topical therapy as well. First, the newer agents (especially fluconazole, itraconazole, and terbinafine) are reviewed, an...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70337-5
更新日期：1996-01-01 00:00:00
abstract：:Patients who present with concerns that they suffer from sexually transmitted infection frequently suffer from other problems. Occasionally it is simply not enough just to demonstrate that the patient has no evidence of sexually transmitted disease, but it is important to diagnose the cause of their symptoms and to re...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：10.1016/s0733-8635(05)70046-2
更新日期：1998-10-01 00:00:00
abstract：:"Nail clipping is a simple technique for diagnosis of several nail unit dermatoses. This article summarizes the practical approach, utility, and histologic findings of a nail clipping in evaluation of onychomycosis, nail unit psoriasis, onychomatricoma, subungual hematoma, melanonychia, and nail cosmetics, and the for...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2014.12.011
更新日期：2015-04-01 00:00:00
abstract：:The craniofacial and oral manifestations of the different epidermolysis bullosa (EB) types vary markedly in character and severity depending largely on the EB type. The tissues affected and the phenotypes displayed are closely related to the specific abnormal or absent proteins resulting from the causative genetic mut...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2009.10.022
更新日期：2010-01-01 00:00:00
abstract：:Liposuction of arms when properly performed with realistic expectations is almost always a "patient pleaser." Patients routinely marvel at the degree of skin contraction that typically occurs. Before and after photos, even as early as 1 week, routinely show dramatic skin contraction when significant volumes of fat are...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：10.1016/s0733-8635(05)70127-3
更新日期：1999-10-01 00:00:00
abstract：:Reconstruction of the nose provides many challenges owing to its differing subunits and varied surfaces. In this article, the nasal anatomy, anesthesia, and some of the reconstructive options available to the dermatologic surgeon are reviewed. These reconstructive options are based on the subunit and depth of the defe...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70489-7
更新日期：1998-01-01 00:00:00
abstract：:Dermatologists can decrease unnecessary use of antimicrobial agents by avoiding them in situations wherein good evidence indicates that they are ineffective. Controlled trials indicate that antimicrobial agents are unhelpful in treating cutaneous abscesses, inflamed epidermal cysts, uninfected atopic eczema, and cutan...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2008.07.003
更新日期：2009-01-01 00:00:00
abstract：:One may accomplish certain closures without tension or distortion using blunt liposuction cannula dissection with or without suction-assisted lipectomy. If closure cannot be accomplished with adequate undermining and an appropriate flap design, the surgeon may first aspirate fat to allow use of the focally expanded sk...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1990-07-01 00:00:00
abstract：:A systematic method of examining nail disorders is important. A patient questionnaire (sample provided) and a basic method of categorizing various problems are helpful tools. Thorough investigation usually yields a diagnosis. ...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：
更新日期：1985-07-01 00:00:00
abstract：:This article discusses ways to recognize and manage lymphomas and pseudolymphomas associated with drug exposure. Over the last 30 years, the classification of pseudolymphomas and lymphomas has undergone significant change, especially following the application of sophisticated immunostaining and gene rearrangement anal...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2007.01.008
更新日期：2007-04-01 00:00:00
abstract：:Since its discovery, the understanding of the roles for TNF-alpha in human biology and disease has grown. Receptors for TNF are found on virtually all cell types, and many physiologic processes seem to be altered by TNF-alpha. The understanding of how TNF-alpha is involved in the pathophysiology of diseases, such as i...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70304-1
更新日期：2001-10-01 00:00:00
abstract：:Chloracne is a rare but important acneiform eruption often associated with the ingestion of chlorinated phenolic agents such as dioxins with subsequent toxicity from these chemicals. Clinically, chloracne can be distinguished from acne vulgaris by the distribution and appearance of the lesions and by taking a detailed...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1990-01-01 00:00:00
abstract：:Treating the underlying pathophysiology of the wound remains of utmost importance. Several new treatment modalities may soon be available as adjunctive treatments. The efficacy of some remains to be established in well-controlled clinical studies. ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70414-9
更新日期：1997-01-01 00:00:00
