The growth of human hair in nude mice.

Abstract:

:The author reviews published papers on human hair growth in nude mice. There is evidence from various sources indicating that grafting of human scalp onto nude mice does not modify significantly morphogenesis, hair follicle structure and function, and composition of the newly grown hair fiber. On the basis of personal observations, the authors further highlights the results obtained in genetic hair defects. Hints are given as to the potential use of the model for drug discovery programs as the product can be used on the human target at early stages of drug development.

journal_name

Dermatol Clin

journal_title

Dermatologic clinics

authors

Neste DV

doi

10.1016/s0733-8635(05)70388-0

subject

Has Abstract

pub_date

1996-10-01 00:00:00

pages

609-17

issue

4

eissn

0733-8635

issn

1558-0520

pii

S0733-8635(05)70388-0

journal_volume

14

pub_type

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