Granulomatous Drug Eruptions.

Abstract:

:Granuloma formation is usually regarded as a means of defending the host from persistent irritants of either exogenous or endogenous origin. Noninfectious granulomatous disorders of the skin encompass a challenging group of diseases owing to their clinical and histologic overlap. Drug reactions characterized by a granulomatous reaction pattern are rare, and defined by a predominance of histiocytes in the inflammatory infiltrate. This review summarizes current knowledge on the various types of granulomatous drug eruptions, focusing on the 4 major types: interstitial granulomatous drug reaction, drug-induced accelerated rheumatoid nodulosis, drug-induced granuloma annulare, and drug-induced sarcoidosis.

journal_name

Dermatol Clin

journal_title

Dermatologic clinics

authors

Dodiuk-Gad RP,Shear NH

doi

10.1016/j.det.2015.03.015

subject

Has Abstract

pub_date

2015-07-01 00:00:00

pages

525-39

issue

3

eissn

0733-8635

issn

1558-0520

pii

S0733-8635(15)00028-5

journal_volume

33

pub_type

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