Vaccines for melanoma. Design strategies and clinical results.

abstract：:Occupational contact dermatitis in hairdressers is a common clinical dermatologic problem. Apparently often secondary to irritant contact dermatitis caused by shampooing in Europe, in North America, allergic contact dermatitis related to the chemicals handled, especially oxidation dyes and permanent waving components,...

journal_title：Dermatologic clinics

authors： Holness DL,Nethercott JR

更新日期：1990-01-01 00:00:00

abstract：:This article provides a detailed review of the vascular manifestations affecting the skin in relationship to internal malignancies. Vascular abnormalities heralding internal malignancies can be divided into three main categories, consisting of disorders related to vascular dilatation (flushing, palmar erythema, and te...

journal_title：Dermatologic clinics

authors： El Tal AK,Tannous Z

更新日期：2008-01-01 00:00:00

abstract：:Infections by VZV, the virus that causes chickenpox and herpes zoster, usually are diagnosed by the classic clinical presentations. In immunocompromised patients, however, the atypical presentation can make the diagnosis more challenging. Although varicella typically follows an uncomplicated course in children, adults...

journal_title：Dermatologic clinics

authors： Chen TM,George S,Woodruff CA,Hsu S

更新日期：2002-04-01 00:00:00

abstract：:Photodynamic therapy (PDT) has had a rapid insurgence into the dermatologic armamentarium of clinicians from all over the world. Its use in actinic keratoses and in non-melanoma skin cancers is well described. Additional uses, including its use in the treatment of photorejuvenation and acne vulgaris and related disord...

journal_title：Dermatologic clinics

authors： Gold MH

更新日期：2007-01-01 00:00:00

abstract：:Hyperhidrosis, characterized by excess sweat production, affects children and adults. Primary focal hyperhidrosis affects any anatomic region with sweat appendages present. Primary hyperhidrosis has traditionally been considered a problem for adults, but approximately 1.6% of adolescents and 0.6% of prepubertal childr...

journal_title：Dermatologic clinics

authors： Bohaty BR,Hebert AA

更新日期：2014-10-01 00:00:00

abstract：:In order to be considered an ectodermal dysplasia, a disorder should meet the following criteria: it must be congenital; it must be diffuse (not localized) and must involve the epidermis as well as at least one of its appendages; and it must not be progressive. Included is a discussion of some well-documented, as well...

journal_title：Dermatologic clinics

authors： Solomon LM,Cook B,Klipfel W

更新日期：1987-01-01 00:00:00

abstract：:This article addresses pigmentary disorders relevant to India. Many of these disorders are easily spotted because of the Indians' darker complexion. The authors examine hypopigmentary and hyperpigmentary disorders, defining the main characteristics of each and their relevance to the people of India, including social a...

journal_title：Dermatologic clinics

authors： Pasricha JS,Khaitan BK,Dash S

更新日期：2007-07-01 00:00:00

abstract：:Atypical gingivostomatitis is recognized by a combination of clinical findings, a sharply marginated, deep red edematous quality to the attached gingiva, angular cheilitis, and a sore red tongue. Unfortunately, there are no general laboratory tests that are diagnostic of the condition, although biopsy of the gingiva s...

journal_title：Dermatologic clinics

authors： Perry HO

更新日期：1987-10-01 00:00:00

abstract：:Guttate and plaque psoriasis are regarded as variants of one disease but present with distinct clinical and histologic appearances. This article focuses special attention on different pathways in the development and clinical course of each, with emphasis on immunologic correlations regarding HLA system linkage and the...

journal_title：Dermatologic clinics

authors： Christophers E,Kiene P

更新日期：1995-10-01 00:00:00

abstract：:Cutaneous manifestations of thyroid disease are protean in nature and can be divided into specific lesions such as the thyroglossal duct cyst and cutaneous metastases from thyroid malignancy, nonspecific signs secondary to thyroid hormone imbalance, and associated dermatologic and systemic disorders. This review repre...

journal_title：Dermatologic clinics

authors： Leonhardt JM,Heymann WR

更新日期：2002-07-01 00:00:00

abstract：:Use of the dissecting stereomicroscope during hair transplant graft dissection has been advocated as a means of reducing hair follicle transection and improving graft growth. The study evaluated the prevalence of hair follicle transection in grafts prepared with and without the dissecting stereomicroscope. Approximate...

journal_title：Dermatologic clinics

authors： Cooley JE,Vogel JE

更新日期：1999-04-01 00:00:00

abstract：:Pemphigus vulgaris, which has multiple clinical variants, is an autoimmune blistering disorder of skin and mucous membranes, usually affecting the elderly, with a strong immunogenetic link. Immunologic studies of this disease have been productive in defining the pathophysiology of blister formation and the characteris...

journal_title：Dermatologic clinics

authors： Becker BA,Gaspari AA

更新日期：1993-07-01 00:00:00

abstract：:We have limited the scope of this article to those disorders that have already been successfully diagnosed or excluded in utero. We currently have the potential to diagnose a number of others for which the opportunity has not yet arisen. If a biochemical, morphologic, chromosomal, or DNA alteration is known for a spec...

journal_title：Dermatologic clinics

authors： Sybert VP,Holbrook KA

更新日期：1987-01-01 00:00:00

abstract：:Although new technologies are becoming available to aid in diagnosis, the skin biopsy continues to be the fundamental tool of the dermatologist to evaluate the nature of a pigmented lesion. There are 3 major techniques for the biopsy of a pigmented lesion: shave biopsy, punch/incisional biopsy, and excisional biopsy. ...

journal_title：Dermatologic clinics

authors： Silverstein D,Mariwalla K

更新日期：2012-07-01 00:00:00

abstract：:As the study of vulvar diseases becomes more accepted and as physicians and patients become more comfortable discussing vulvar complaints, there will also be less hesitancy to examine the area adequately. This can only lead to better observations, more knowledge, and more exact diagnosis and treatment of these problem...

journal_title：Dermatologic clinics

authors： Turner ML

更新日期：1992-04-01 00:00:00

abstract：:The anatomic region influences the dermoscopic features of different lesions. In this article, the particular characteristics of the scalp, mucosal membranes, and lesions located on the milk line are explained. In histopathology, the benign melanocytic lesions in these locations are also named nevi of special sites, c...

journal_title：Dermatologic clinics

authors： Hofmann-Wellenhof R

更新日期：2013-10-01 00:00:00

abstract：:This article, rather than presenting an overview of all available antifungal agents, has provided an update on new information about older agents, as well as evolving information about new agents, including those currently undergoing clinical trials. Among the azoles, ketoconazole will continue to be used as a major a...

journal_title：Dermatologic clinics

authors： Lesher JL Jr

更新日期：1992-10-01 00:00:00

abstract：:Six persons involved with cultivation trials of Phacelia spp. developed a contact allergy to certain plants of this species. Geranyl(hydro)quinone and related substances, including the geranylhydroquinone geroquinol (INN), which has been introduced as a radioprotective agent, are potent allergens and probably are more...

journal_title：Dermatologic clinics

authors： Ippen H

更新日期：1990-01-01 00:00:00

abstract：:The umbrella term psoriasis is now understood to incorporate several distinct phenotypes or endotypes along the disease spectrum that in turn will dictate different therapies. A stratified medicine approach to psoriasis using this clinical information coupled with pharmacogenomic and immunologic data will become more ...

journal_title：Dermatologic clinics

authors： Menter MA,Griffiths CE

更新日期：2015-01-01 00:00:00

abstract：:Most melanocytic tumors can be characterized as a benign nevus or a melanoma by a trained pathologist using traditional histopathological methods. However, a minority demonstrates ambiguous features and continues to be a diagnostic challenge. Genetic expression profiling (GEP) assays have been developed in an effort t...

journal_title：Dermatologic clinics

authors： Leachman SA,Mengden Koon S,Korcheva VB,White KP

更新日期：2017-10-01 00:00:00

abstract：:This article discusses complications with the use of botulinum toxin. The following topics are explored: conditions caused by muscle spasms, resistance to botulinum toxin, cosmetic use of botulinum toxin, complications in treating hyperhidrosis, treatment of migraine headaches, and informed consent. ...

journal_title：Dermatologic clinics

authors： Klein AW

更新日期：2004-04-01 00:00:00

abstract：:Psoriasis vulgaris is a chronic inflammatory skin disease that results from the complex interplay between keratinocytes, dendritic cells, and T cells. Keratinocytes trigger innate and adaptive immune responses. Dermal myeloid dendritic cells regulate T cell activation and production of cytokines and chemokines that am...

journal_title：Dermatologic clinics

authors： Kim J,Krueger JG

更新日期：2015-01-01 00:00:00

abstract：:Chromoblastomycosis is a chronic cutaneous infection due to several varieties of pigmented fungi. Diagnosis is straightforward and based on clinical and microscopic findings. Despite the protracted course of the disease, dissemination of the infection is rare. New insights into the pathophysiology may permit a closer ...

journal_title：Dermatologic clinics

authors： Elgart GW

更新日期：1996-01-01 00:00:00

abstract：:Nail pigmentation is defined by the presence of melanin in the nail plate. It most frequently has the appearance of a longitudinal pigmented band, called longitudinal mel-anonychia (LM). LM is an important aspect of ungual pathology because it can be the first sign of nail apparatus melanoma. The aim of this article i...

journal_title：Dermatologic clinics

authors： André J,Lateur N

更新日期：2006-07-01 00:00:00

abstract：:Cosmeceuticals are topically applied products that are more than merely cosmetic, yet are not true drugs that have undergone rigorous placebo controlled studies for safety and efficacy. There are many review articles that outline the theoretical biologic and clinical actions of these cosmeceuticals and their various i...

journal_title：Dermatologic clinics

authors： Reszko AE,Berson D,Lupo MP

更新日期：2009-10-01 00:00:00

abstract：:In part because of the increased public awareness regarding skin cancer, patients are presenting to their physician with thinner melanomas. Many lesions are now found in the in situ phase. The vast majority of melanomas referred to or diagnosed in the Skin Oncology Program at Boston University are less than 2 mm in th...

journal_title：Dermatologic clinics

authors： Rogers GS

更新日期：1991-10-01 00:00:00

abstract：:Liposuction is the most popular cosmetic surgical procedure performed in men. Aside from traditional liposuction using the tumescent technique, several energy-assisted liposuction technologies have emerged and been proven safe and particularly beneficial for the male patient demographic. The differences in fat distrib...

journal_title：Dermatologic clinics

authors： Karcher C

更新日期：2018-01-01 00:00:00

abstract：:Patient-centered care in dermatologic surgery emphasizes addressing the preferences, values, and concerns of the surgical patient in an effort to improve the overall experience. Impediments affecting the delivery of Mohs micrographic surgical treatment of skin cancers are present throughout the perioperative period. D...

journal_title：Dermatologic clinics

authors： Lee MP,Zullo SW,Sobanko JF,Etzkorn JR

更新日期：2019-07-01 00:00:00

abstract：:Ultraviolet (UV) radiation contributes to the development of skin cancer through direct and indirect DNA damage, production of reactive oxygen species, and local immunomodulation. The association between UV radiation and skin cancer has raised concern for the risk of carcinogenesis following phototherapy. The photocar...

journal_title：Dermatologic clinics

authors： Thompson KG,Kim N

更新日期：2020-01-01 00:00:00

abstract：:Epidermolysis bullosa (EB) in Mexico continues to be a rare genodermatosis that is still unknown for most of the health care professionals in the country. The spirit of DebRA MEXICO was born in 1994 when the Mexican health care team started to see patients with the main purpose to provide medical care, genetic counsel...

journal_title：Dermatologic clinics

authors： Liy-Wong C,Cepeda-Valdes R,Salas-Alanis JC

更新日期：2010-04-01 00:00:00