Abstract:
:The carcinoid syndrome and its clinical manifestations have been discussed. The standard laboratory test for making that diagnosis is urinary 5-HIAA levels but newer, more sensitive tests may also be available.
journal_name
Dermatol Clinjournal_title
Dermatologic clinicsauthors
Farmer KLsubject
Has Abstractpub_date
1994-01-01 00:00:00pages
191-9issue
1eissn
0733-8635issn
1558-0520journal_volume
12pub_type
杂志文章,评审abstract::The recalcitrance of rosacea to many treatment options may prompt patients to spend exorbitant amounts of money on unsubstantiated treatment regimens in an effort to achieve relief. The authors examine the relationship between disease severity and treatment cost across several demographic and socioeconomic strata. Fam...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/j.det.2017.11.012
更新日期:2018-04-01 00:00:00
abstract::Antimalarial compounds have been demonstrated to be both safe and efficacious in the treatment of lupus erythematosus as well as several other dermatologic conditions. It is imperative, however, that physicians familiarize themselves with the potential complications associated with the use of these agents. Furthermore...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1992-07-01 00:00:00
abstract::Human papillomavirus infections of the skin and anogenital tract are common. The association of these viruses with neoplasia, particularly of the anogenital tract, has stimulated efforts to devise practical methods of detection and typing of HPV. Although experimental diagnostic tests are available, they are, for the ...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1991-04-01 00:00:00
abstract::Dermatologists can decrease unnecessary use of antimicrobial agents by avoiding them in situations wherein good evidence indicates that they are ineffective. Controlled trials indicate that antimicrobial agents are unhelpful in treating cutaneous abscesses, inflamed epidermal cysts, uninfected atopic eczema, and cutan...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2008.07.003
更新日期:2009-01-01 00:00:00
abstract::Calciphylaxis is defined by the presence of calcium deposits within the wall of small and medium-sized vessels. It is classically considered a life-threatening disease in patients with end-stage renal disease under dialysis. Clinically, it is characterized by the presence of painful plaques surrounded by a reticulate ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2008.05.006
更新日期:2008-10-01 00:00:00
abstract::Tetracyclines are known to exhibit multiple significant anti-inflammatory actions. This article describes the mechanisms of this anti-inflammatory activity, such as inhibition of chemotaxis, granuloma formation, and protease. The article also discusses the effectiveness of tetracyclines in treating such diseases as ac...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2007.01.012
更新日期:2007-04-01 00:00:00
abstract::Exanthematous eruptions, urticaria, photosensitivity, pigmentary problems, acne, alopecia, fixed drug eruptions, and lichenoid reactions are the most common dermatologic side effects associated with the administration of psychopharmacologic agents. The cutaneous findings associated with the various eruptions and the m...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70378-8
更新日期:1996-07-01 00:00:00
abstract::Melanoma vaccines represent a novel and potentially effective method of slowing the progression of melanoma. This article discusses the importance in the design of vaccines for melanoma, the relative advantages and disadvantages of this approach, and summarizes the results of the most important clinical trials conduct...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70009-7
更新日期:1998-04-01 00:00:00
abstract::A discussion of the pathologic findings found with aging and photodamage is used to formulate a rational preoperative regimen, treatment technique, and maintenance regimen. Details of laser treatment technique, anesthesia, and postoperative care are given. Possible contraindications are discussed, as are the pros and ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70452-6
更新日期:1997-07-01 00:00:00
abstract::Although new technologies are becoming available to aid in diagnosis, the skin biopsy continues to be the fundamental tool of the dermatologist to evaluate the nature of a pigmented lesion. There are 3 major techniques for the biopsy of a pigmented lesion: shave biopsy, punch/incisional biopsy, and excisional biopsy. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2012.04.013
更新日期:2012-07-01 00:00:00
abstract::Sensitive skin is a complex problem with genetic, individual, environmental, occupational, and ethnic implications. Further work is needed to rank irritants and irritant reactions to classify sensitive skin on the basis of standard models. The development of topical products designed for sensitive and ethnic skin may ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1991-01-01 00:00:00
abstract::Among the different classes and complexities of antiretroviral regimens, maximal viral suppression, sustained durability, increased CD4 count, decreased evolving resistance, and fewer side effects combined with increased compliance resulting in decreased morbidity and mortality remain the goals of therapy. Serial vira...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70314-4
更新日期:2001-10-01 00:00:00
abstract::Traditional chemotherapies, interleukins, phosphorylase inhibitors, and proteasome inhibitors are important therapies available to patients with cutaneous T-cell lymphoma (CTCL). Traditional chemotherapies, both in combination and as single agents, are commonly used in relapsed, refractory CTCLs that behave in an aggr...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2015.05.012
更新日期:2015-10-01 00:00:00
abstract::Atypical gingivostomatitis is recognized by a combination of clinical findings, a sharply marginated, deep red edematous quality to the attached gingiva, angular cheilitis, and a sore red tongue. Unfortunately, there are no general laboratory tests that are diagnostic of the condition, although biopsy of the gingiva s...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1987-10-01 00:00:00
abstract::Contact dermatitis is a common skin disease caused by contact with irritants or allergens. Irritant contact dermatitis is a result of nonspecific irritant factors, which cause activation of mainly innate immunity, resulting in skin inflammation. Contact hypersensitivity, which manifests itself as allergic contact derm...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2007.06.002
更新日期:2007-10-01 00:00:00
abstract::Traumatic panniculitis refers to changes in the subcutaneous fat related to physical or chemical agents. The clinical picture of traumatic panniculitis is nonspecific. Cutaneous lesions are indurated, warm, red, subcutaneous plaques or nodules not necessary related to the intensity of the injury. The histologic pictur...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2008.06.004
更新日期:2008-10-01 00:00:00
abstract::The excessive sweating of hyperhidrosis creates profound psychosocial, professional, and financial burdens on the individual sufferer; it contributes to impaired self-worth and self-efficacy, decreased satisfaction in all relationships, avoidance of specific careers, and increased expenditures on everything from cloth...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2014.06.011
更新日期:2014-10-01 00:00:00
abstract::Cutaneous B-cell lymphomas represent a heterogeneous group of entities which show variation in histology, immunophenotype, and in prognosis. In the current review the morphologic spectrum of cutaneous B-cell lymphomas comprising primary and secondary cutaneous B-cell lymphomas is discussed according to the REAL classi...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70109-1
更新日期:1999-07-01 00:00:00
abstract::Pemphigoid gestationis is a rare, autoimmune bullous disease of pregnancy that involves autoantibodies directed against type XVII collagen in the basement membrane zone. This article discusses the immunopathogenesis, diagnostic methods, and clinical features of this fascinating disease. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2011.03.002
更新日期:2011-07-01 00:00:00
abstract::This article, rather than presenting an overview of all available antifungal agents, has provided an update on new information about older agents, as well as evolving information about new agents, including those currently undergoing clinical trials. Among the azoles, ketoconazole will continue to be used as a major a...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1992-10-01 00:00:00
abstract::Ultraviolet (UV) radiation contributes to the development of skin cancer through direct and indirect DNA damage, production of reactive oxygen species, and local immunomodulation. The association between UV radiation and skin cancer has raised concern for the risk of carcinogenesis following phototherapy. The photocar...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2019.08.003
更新日期:2020-01-01 00:00:00
abstract::The general goals of medical management of vitiligo are to repigment vitiliginous areas of skin and to stabilize the progression of depigmentation. However, for some patients with vitiligo affecting extensive body surface areas who are unresponsive to repigmentation therapies, depigmentation of the remaining normal sk...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2016.11.010
更新日期:2017-04-01 00:00:00
abstract::There are numerous cutaneous findings associated with liver diseases. Although most of these changes are nonspecific and therefore are of limited value in the actual diagnosis of hepatic disease, recognition of the association may be useful for diagnosis and for monitoring the patient's response to treatment. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1989-07-01 00:00:00
abstract::The diagnosis of lymphoma currently relies on a combination of clinical, routine histopathologic, and immunohistochemical studies, sometimes supplemented by other special techniques such as flow cytometry, DNA analysis, and gene rearrangement study. This review considers the practical diagnosis of cutaneous lymphoma, ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract::Hyperhidrosis, characterized by excess sweat production, affects children and adults. Primary focal hyperhidrosis affects any anatomic region with sweat appendages present. Primary hyperhidrosis has traditionally been considered a problem for adults, but approximately 1.6% of adolescents and 0.6% of prepubertal childr...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2014.06.005
更新日期:2014-10-01 00:00:00
abstract::Current aesthetic dermatology rejuvenation options offer minimally invasive, more affordable alternatives to traditional cosmetic surgery. Chemical peels and laser resurfacing can significantly improve the appearance of the skin and stimulate neocollagenesis; botulinum toxin reduces the appearance of dynamic facial li...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2009.08.013
更新日期:2009-10-01 00:00:00
abstract::Many substances have historically been used to address facial soft tissue defects. Currently in the United States autologous fat and injectable bovine collagen are the most commonly utilized injectable fillers. Additionally, the judicious application of BOTOX in the upper face as well as neck has all but revolutionize...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70469-1
更新日期:1997-10-01 00:00:00
abstract::The author reviews published papers on human hair growth in nude mice. There is evidence from various sources indicating that grafting of human scalp onto nude mice does not modify significantly morphogenesis, hair follicle structure and function, and composition of the newly grown hair fiber. On the basis of personal...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70388-0
更新日期:1996-10-01 00:00:00
abstract::Treatment of autoimmune patients can be challenging and rewarding. These patients often remain undiagnosed for prolonged periods of time or underdiagnosed without immunologic confirmation, resulting in significant morbidity. The most important principle in management of autoimmune bullous disease is to halt blistering...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2016.02.001
更新日期:2016-07-01 00:00:00
abstract::The development and use of various laser systems for the treatment of carcinomas of the skin constitute a relatively new therapeutic approach. Because the skin is a readily accessible organ, it is an excellent site at which to attempt different therapeutic modalities. What is truly astounding has been the development ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1991-10-01 00:00:00