Abstract：
:Porphyria cutanea tarda is a photocutaneous syndrome characterized clinically by cutaneous fragility, bullae, hypertrichosis, pigmentary changes, and sclerodermoid plaques and characterized biochemically by hepatic overproduction and storage of excessive amounts of porphyrins. Porphyria cutanea tarda, the most common disorder of porphyrin metabolism, must be differentiated from variegate porphyria, hereditary coproporphyria, bullous dermatosis of hemodialysis, and drug-related pseudoporphyria.
journal_name
Dermatol Clinjournal_title
Dermatologic clinicsauthors
Grossman ME,Poh-Fitzpatrick MBsubject
Has Abstractpub_date
1986-04-01 00:00:00pages
297-309issue
2eissn
0733-8635issn
1558-0520journal_volume
4pub_type
杂志文章abstract：:There is a spectrum of melanocytic tumors from benign to malignant. The goal of the dermatologist is to identify and remove early melanomas because doing so can be lifesaving. At the same time, it is inappropriate to randomly remove benign nevi. Dermatoscopy is an additional tool that can be used to help discriminate ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70269-2
更新日期：2001-04-01 00:00:00
abstract：:Traditional chemotherapies, interleukins, phosphorylase inhibitors, and proteasome inhibitors are important therapies available to patients with cutaneous T-cell lymphoma (CTCL). Traditional chemotherapies, both in combination and as single agents, are commonly used in relapsed, refractory CTCLs that behave in an aggr...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2015.05.012
更新日期：2015-10-01 00:00:00
abstract：:A compendium of uncommon dermatologic treatments, both medical and surgical, are presented. This article is based on a survey of the members of the Noah Worcester Dermatologic Society with subsequent additions, including treatment pearls from the Internet and other contributions from practicing dermatologists, as well...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70179-0
更新日期：2000-04-01 00:00:00
abstract：:It is quite evident the pathogenesis of psoriasis is modulated by immune-mediated mechanisms that invoke activated T cells and inflammatory cytokines, such as tumor necrosis factor-alpha. Current immunosuppressive systemic treatments may be effective in controlling psoriasis to a certain degree but have significant dr...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2003.12.002
更新日期：2004-10-01 00:00:00
abstract：:Hepatic itch remains among the most agonizing symptoms for affected patients and a major clinical challenge for physicians. Pruritus may occur in almost all liver diseases, particularly those with cholestatic features. Hepatic itch arises irrespective of the severity of the underlying liver disease or extent of choles...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2018.02.008
更新日期：2018-07-01 00:00:00
abstract：:This article presents solutions to difficult surgical repair problems. Solutions for the repair of defects in the ear (in this case the ear lobule) and upper lip are discussed. A solution is also provided for an exasperating problem that arises when cheek and neck lifts are done. An aid for the design of cutaneous fla...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:The success of the Mohs procedure depends on the reliability of each step in the technique. Pitfalls in histologic preparation of the tissue specimens may occur during debulking, excising, orienting, creating the map, sectioning, inking, tissue flattening and freezing, cutting, slide fixation, staining, and mapping th...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2011.01.002
更新日期：2011-04-01 00:00:00
abstract：:Atypical gingivostomatitis is recognized by a combination of clinical findings, a sharply marginated, deep red edematous quality to the attached gingiva, angular cheilitis, and a sore red tongue. Unfortunately, there are no general laboratory tests that are diagnostic of the condition, although biopsy of the gingiva s...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1987-10-01 00:00:00
abstract：:Histoplasmosis is caused by Histoplasma capsulatum, a dimorphic fungus. Because histoplasmosis is usually a self-limited disease in the majority of cases, treatment often is not needed in the normal host. However, severe cases of acute pulmonary histoplasmosis require therapy. Amphotericin B is considered the treatmen...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1989-04-01 00:00:00
abstract：:Psoriasis vulgaris is a chronic inflammatory skin disease that results from the complex interplay between keratinocytes, dendritic cells, and T cells. Keratinocytes trigger innate and adaptive immune responses. Dermal myeloid dendritic cells regulate T cell activation and production of cytokines and chemokines that am...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2014.09.002
更新日期：2015-01-01 00:00:00
abstract：:Contact dermatitis is the most common occupational skin disorder, responsible for up to 30% of all cases of occupational disease in industrialized nations. Epidemiologic data suggest that contact dermatitis accounts for 90% to 95% of all cases of occupational skin disease, imposing considerable social and economic imp...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2009.05.002
更新日期：2009-07-01 00:00:00
abstract：:Hair transplantation has developed into a refined art in the past 30 years. Refined techniques and instruments, appreciation of properly placed hairlines, better methods of harvesting donor grafts, and better cutting materials in punches have significantly improved results in one of the most frequently performed cosme...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1987-07-01 00:00:00
abstract：:The large-scale deployment of low-cost, noninvasive mechanisms of early detection are needed to reduce the melanoma burden. A serial 2-step system could power mass screening efforts serving the uninsured and underinsured as well as the rural and remote US counties where melanoma mortality is doubled for lack of access...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2017.06.005
更新日期：2017-10-01 00:00:00
abstract：:Infections by VZV, the virus that causes chickenpox and herpes zoster, usually are diagnosed by the classic clinical presentations. In immunocompromised patients, however, the atypical presentation can make the diagnosis more challenging. Although varicella typically follows an uncomplicated course in children, adults...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(01)00012-2
更新日期：2002-04-01 00:00:00
abstract：:Melanoma vaccines represent a novel and potentially effective method of slowing the progression of melanoma. This article discusses the importance in the design of vaccines for melanoma, the relative advantages and disadvantages of this approach, and summarizes the results of the most important clinical trials conduct...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70009-7
更新日期：1998-04-01 00:00:00
abstract：:Liposuction is the most popular cosmetic surgical procedure performed in men. Aside from traditional liposuction using the tumescent technique, several energy-assisted liposuction technologies have emerged and been proven safe and particularly beneficial for the male patient demographic. The differences in fat distrib...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2017.09.010
更新日期：2018-01-01 00:00:00
abstract：:Bullous disease in children can be confusing clinically and challenging to mange. Five groups of autoimmune bullous disease are discussed with emphasis on unique features in children. Pemphigus (vulgaris, foliaceus, neonatal), pemphigoid (bullous and cicatricial), dermatitis herpetiformis, linear IgA dermatosis, and e...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1993-07-01 00:00:00
abstract：:Nasal reconstruction can be challenging due to the complex nature of multiple cosmetic units and functional considerations. This article discusses single- and two-staged melolabial flap repairs for nasal reconstruction following removal of skin cancers. ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2004.08.003
更新日期：2005-01-01 00:00:00
abstract：:Atopic dermatitis is associated with significant patient burden, with impacts from symptoms and visible physical manifestations of the disease. Consequences include detrimental effects on quality of life (QoL), sleep, self-esteem, interpersonal relationships, participation in leisure and sports, and attendance or perf...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2017.02.004
更新日期：2017-07-01 00:00:00
abstract：:Colored cosmetics are an important part of the dermatologic armamentarium. They can camouflage contour and pigment abnormalities, provide moisturization, enhance oil control, add sun protection, deliver barrier-enhancing agents, increase acne treatment, and create a sense of personal well-being. Familiarity with these...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：10.1016/s0733-8635(05)70213-8
更新日期：2000-10-01 00:00:00
abstract：:To remain experts in skin care and treatment, every dermatologist must be aware of the evolving role of soft tissue fillers in dermatology. Patients with facial scarring, lipodystrophy, contour abnormalities, and age- and sun-induced rhytids can be successfully treated. A literature review, industry recommendations, a...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2004.09.009
更新日期：2005-04-01 00:00:00
abstract：:In this article, the use of selected psychopharmacologic medications was explained in detail. If a patient who is obviously suffering from a psychiatric component of his or her disorder that can be responsive to psychopharmacotherapy refuses to accept a referral to a psychiatrist or other mental health professional, t...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：:The umbrella term psoriasis is now understood to incorporate several distinct phenotypes or endotypes along the disease spectrum that in turn will dictate different therapies. A stratified medicine approach to psoriasis using this clinical information coupled with pharmacogenomic and immunologic data will become more ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2014.09.012
更新日期：2015-01-01 00:00:00
abstract：:Hidradenitis suppurativa (HS) is a chronic, inflammatory, scarring condition involving the intertriginous skin of the axillary, inguinal, inframammary, genital, and perineal areas of the body. It is also referred to as acne inversa and Verneuil disease. Follicular occlusion is the primary event in HS. It is now accept...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2010.07.003
更新日期：2010-10-01 00:00:00
abstract：:KS remains a challenge to clinicians and investigators more than a century after its initial description. Debate continues as to the cell of origin, as well as whether or not it is a true cancer. KS appears to be an opportunistic neoplasm, which in its earliest phase retains some features of a benign hyperproliferativ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70424-1
更新日期：1997-01-01 00:00:00
abstract：:Although trichoscopy has only recently been introduced in the assessment of hair and scalp disorders, it is already considered an essential diagnostic tool by many experts in the field. This article discusses topics that are often a source of doubt among clinicians, and tips that may help dermatologists better perform...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2018.05.008
更新日期：2018-10-01 00:00:00
abstract：:Kaposi sarcoma (KS) is an angioproliferative mesenchymal neoplasm caused by Kaposi sarcoma-related herpesvirus. This review outlines our current understanding of the epidemiology, pathogenesis, clinical presentation, and staging for this disease. Recent research has informed a more comprehensive understanding of the e...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2019.05.008
更新日期：2019-10-01 00:00:00
abstract：:This article reviews the role of dermatologists in occupational dermatologic care by reviewing the types of skin diseases that may be work-related, the diagnostic testing, and evidence of quality of care delivery and outcomes provided by dermatologists. ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70169-8
更新日期：2000-04-01 00:00:00
abstract：:Systemic drugs or ingestants may affect the nails. Changes vary from asymptomatic growth rate changes and pigmentation abnormalities to nail shedding and permanent deformity. The former two changes are most common. Presented are changes in nails caused by antibiotics, cancer chemotherapeutic drugs, poisons and ingesta...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：
更新日期：1985-07-01 00:00:00
abstract：:The clinical diagnosis of malignant melanoma requires the following: an acceptance of the concept of "in situ" malignancy, both clinically and histologically; a high index of suspicion concerning any pigmented lesion; recalling the mnemonic "remember your A,B,C,D's"; and a knowledge of the clinical simulators of malig...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：
更新日期：1985-04-01 00:00:00
