Abstract:
:Dermatologic infections are treated to improve the elderly patient's quality of life and prevent disability and death. Pharmacokinetic changes, social issues, and the risk for adverse effects and drug interactions, however, increase the challenge to achieve successful treatment of those over age 65 as compared with younger patients. This challenge grows ever larger when coupled with the increasing trends of resistance among bacteria and fungi. The clinician can effectively face this challenge through careful consideration of diagnosis, patient risk factors, antimicrobial pharmacology, and resistance patterns.
journal_name
Dermatol Clinjournal_title
Dermatologic clinicsauthors
Hutchison LCdoi
10.1016/s0733-8635(03)00112-8subject
Has Abstractpub_date
2004-01-01 00:00:00pages
63-71issue
1eissn
0733-8635issn
1558-0520pii
S0733-8635(03)00112-8journal_volume
22pub_type
杂志文章,评审abstract::A discussion of the pathologic findings found with aging and photodamage is used to formulate a rational preoperative regimen, treatment technique, and maintenance regimen. Details of laser treatment technique, anesthesia, and postoperative care are given. Possible contraindications are discussed, as are the pros and ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70452-6
更新日期:1997-07-01 00:00:00
abstract::Nail psoriasis, melanonychia striata, and onychomycosis are relatively common nail disorders that have generated much research into their pathophysiology and treatment. The authors hope this discussion of the recent therapeutic developments for treating these disorders will not only inform but will also inspire furthe...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70145-5
更新日期:2000-01-01 00:00:00
abstract::The Armed Forces Institute of Pathology (AFIP) is well known for providing expert pathology in many specialties and educational courses for civilian and military personnel. Some of the departments at the AFIP have also developed expertise in various advanced laboratory techniques for diagnosis and research that are ap...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70074-7
更新日期:1999-01-01 00:00:00
abstract::Traditional chemotherapies, interleukins, phosphorylase inhibitors, and proteasome inhibitors are important therapies available to patients with cutaneous T-cell lymphoma (CTCL). Traditional chemotherapies, both in combination and as single agents, are commonly used in relapsed, refractory CTCLs that behave in an aggr...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2015.05.012
更新日期:2015-10-01 00:00:00
abstract::This article provides a protocol for the systematic approach to the technique of Mohs micrographic surgery. Each step, from tumor excision and tissue mapping, to specimen processing and histologic interpretation, through wound closure and postoperative management, is covered. The advantages of Mohs surgery over other ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2011.02.002
更新日期:2011-04-01 00:00:00
abstract::Cyanoacrylates (CAs) were not widely adopted for medical use until recently because of lingering concerns regarding the initial tissue toxicities of the short-chain CAs. The medium-chain CAs, primarily butyl-cyanoacrylate, have been widely used in Europe and Canada for several decades and have gone a long way in dispe...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2004.09.003
更新日期:2005-04-01 00:00:00
abstract::The craniofacial and oral manifestations of the different epidermolysis bullosa (EB) types vary markedly in character and severity depending largely on the EB type. The tissues affected and the phenotypes displayed are closely related to the specific abnormal or absent proteins resulting from the causative genetic mut...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2009.10.022
更新日期:2010-01-01 00:00:00
abstract::There has been a resurgence over the past decade of microlipoinjection. Adipose tissue has proved to be a safe and effective filler substance for subcutaneous defects. More recently, lipocytic dermal augmentation, or autologous collagen, has been used to correct dermal defects. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1995-04-01 00:00:00
abstract::Systemic retinoids represent a growing armamentarium in the treatment of a wide range of skin disorders and malignancies. Although these drugs can have substantial toxicities, their wise use can result in safe and efficacious therapy that can alter dramatically the lives of individuals with severe skin disorders. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70237-0
更新日期:2001-01-01 00:00:00
abstract::Infections by VZV, the virus that causes chickenpox and herpes zoster, usually are diagnosed by the classic clinical presentations. In immunocompromised patients, however, the atypical presentation can make the diagnosis more challenging. Although varicella typically follows an uncomplicated course in children, adults...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(01)00012-2
更新日期:2002-04-01 00:00:00
abstract::Human papillomaviruses are a heterogeneous group of DNA tumor viruses associated with hyperplastic (warts, condylomata), dysplastic (CIN and VIN), and malignant lesions (carcinomas) of squamous epithelium. Each HPV type is preferentially associated with specific clinical lesions and has an anatomic site preference for...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1991-04-01 00:00:00
abstract::This article provides an overview of the resurfacing technique of dermabrasion. Preoperative consultation, perioperative medications, postoperative management, common complications, and reasonable outcome expectations are all described in detail. A description of proper technique, intraoperative equipment, and an appr...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/s0733-8635(05)70284-9
更新日期:2001-07-01 00:00:00
abstract::Chloracne is a rare but important acneiform eruption often associated with the ingestion of chlorinated phenolic agents such as dioxins with subsequent toxicity from these chemicals. Clinically, chloracne can be distinguished from acne vulgaris by the distribution and appearance of the lesions and by taking a detailed...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1990-01-01 00:00:00
abstract::Use of the dissecting stereomicroscope during hair transplant graft dissection has been advocated as a means of reducing hair follicle transection and improving graft growth. The study evaluated the prevalence of hair follicle transection in grafts prepared with and without the dissecting stereomicroscope. Approximate...
journal_title:Dermatologic clinics
pub_type: 杂志文章,多中心研究
doi:10.1016/s0733-8635(05)70089-9
更新日期:1999-04-01 00:00:00
abstract::Vasculitis may be defined as damage to blood vessels induced by pathologic processes, resulting in compromise of function of the organ in which the blood vessels reside. A large number of syndromes and disease processes exist in which vasculitis plays a key role. Selected vasculitic syndromes of special interest to de...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1990-10-01 00:00:00
abstract::Six persons involved with cultivation trials of Phacelia spp. developed a contact allergy to certain plants of this species. Geranyl(hydro)quinone and related substances, including the geranylhydroquinone geroquinol (INN), which has been introduced as a radioprotective agent, are potent allergens and probably are more...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Atypical gingivostomatitis is recognized by a combination of clinical findings, a sharply marginated, deep red edematous quality to the attached gingiva, angular cheilitis, and a sore red tongue. Unfortunately, there are no general laboratory tests that are diagnostic of the condition, although biopsy of the gingiva s...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1987-10-01 00:00:00
abstract::"Nail clipping is a simple technique for diagnosis of several nail unit dermatoses. This article summarizes the practical approach, utility, and histologic findings of a nail clipping in evaluation of onychomycosis, nail unit psoriasis, onychomatricoma, subungual hematoma, melanonychia, and nail cosmetics, and the for...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2014.12.011
更新日期:2015-04-01 00:00:00
abstract::This article describes major screening studies of the past two decades, discusses the evidence-based screening recommendations, highlights the need to screen high-risk and previously unscreened populations, and concludes with suggestions for risk assessment and physician-nurse training in the skin cancer examination. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(02)00034-7
更新日期:2002-10-01 00:00:00
abstract::Advances in laser technology now permit the physician to provide an effective form of treatment for a large variety of cutaneous disorders for which no previous therapy or only poor forms of therapy previously existed. Additional refinements in both laser instruments and treatment techniques are certain to have a prof...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1987-04-01 00:00:00
abstract::Much progress has been made over the past 10 years with regard to development of a vaccine active against HPV. Successful protection has been achieved in animal models using species-specific papillomaviruses; however, HPV diversity may delay the development of successful HPV vaccines, especially those designed as ther...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/s0733-8635(05)70056-5
更新日期:1998-10-01 00:00:00
abstract::Pemphigus is an autoimmune intraepithelial blistering disease of the skin and mucous membranes that is characterized in part by the presence of circulating IgG autoantibodies. These autoantibodies, which have been shown to be pathogenic, bind to complexes on the keratinocyte cell surface and have been utilized to esta...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1990-10-01 00:00:00
abstract::This article is a tribute to clinician Henry M. Lewis. The author shares practical therapeutic pearls developed and used over the years by Dr. Lewis. ...
journal_title:Dermatologic clinics
pub_type: 传,历史文章,杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::The systematic evaluation of photosensitive patients involves a comprehensive history, physical examination, phototesting, and, if necessary, photopatch testing and laboratory evaluation. Polymorphous light eruption, chronic actinic dermatitis, solar urticaria, and photosensitivity secondary to systemic medications ar...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2014.03.006
更新日期:2014-07-01 00:00:00
abstract::Exanthematous eruptions, urticaria, photosensitivity, pigmentary problems, acne, alopecia, fixed drug eruptions, and lichenoid reactions are the most common dermatologic side effects associated with the administration of psychopharmacologic agents. The cutaneous findings associated with the various eruptions and the m...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70378-8
更新日期:1996-07-01 00:00:00
abstract::Gardner's syndrome is an autosomal dominant genodermatosis. Familial polyposis of the colon, osteomas, and cutaneous epidermoid cysts are characteristic features. Colon cancer will develop in all affected individuals unless prophylactic colectomy is performed. The follow-up and management of patients with Gardner's sy...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1995-01-01 00:00:00
abstract::Many genodermatoses have distinct oral features that may help identify or confirm a genetic diagnosis. Oral features of the disorders described here are summarized in Table 1. These conditions provide clear examples of rapid progress in the field of genetic technology relevant to patient care. Less than a decade ago, ...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/s0733-8635(02)00082-7
更新日期:2003-01-01 00:00:00
abstract::The management of onychomycosis using topical agents has improved with the introduction of ciclopirox and amorolfine nail lacquers; other topical agents may be less effective. The combination of a nail lacquer with an oral antifungal agent may further improve efficacy rates in certain clinical presentations (eg, among...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(03)00025-1
更新日期:2003-07-01 00:00:00
abstract::The varied histopathology of the reactive inflammatory vascular dermatoses requires close cooperation between the clinician and the pathologist. This article presents an overview of the histology of this group of dermatoses, including the figurate erythemas, the pigmented purpuric eruptions, urticaria and urticarial v...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::There have been many advances during the past few years relating to the treatment of superficial fungal infections. This article focuses on recent developments, particularly in oral therapy, but in topical therapy as well. First, the newer agents (especially fluconazole, itraconazole, and terbinafine) are reviewed, an...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70337-5
更新日期:1996-01-01 00:00:00