Antimicrobial therapy and resistance in dermatologic pathogens of the elderly.

Abstract:

:Dermatologic infections are treated to improve the elderly patient's quality of life and prevent disability and death. Pharmacokinetic changes, social issues, and the risk for adverse effects and drug interactions, however, increase the challenge to achieve successful treatment of those over age 65 as compared with younger patients. This challenge grows ever larger when coupled with the increasing trends of resistance among bacteria and fungi. The clinician can effectively face this challenge through careful consideration of diagnosis, patient risk factors, antimicrobial pharmacology, and resistance patterns.

journal_name

Dermatol Clin

journal_title

Dermatologic clinics

authors

Hutchison LC

doi

10.1016/s0733-8635(03)00112-8

subject

Has Abstract

pub_date

2004-01-01 00:00:00

pages

63-71

issue

1

eissn

0733-8635

issn

1558-0520

pii

S0733-8635(03)00112-8

journal_volume

22

pub_type

杂志文章,评审
  • Laser resurfacing of rhytides.

    abstract::A discussion of the pathologic findings found with aging and photodamage is used to formulate a rational preoperative regimen, treatment technique, and maintenance regimen. Details of laser treatment technique, anesthesia, and postoperative care are given. Possible contraindications are discussed, as are the pros and ...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8635(05)70452-6

    authors: Fitzpatrick RE

    更新日期:1997-07-01 00:00:00

  • Developments in the treatment of nail psoriasis, melanonychia striata, and onychomycosis. A review of the literature.

    abstract::Nail psoriasis, melanonychia striata, and onychomycosis are relatively common nail disorders that have generated much research into their pathophysiology and treatment. The authors hope this discussion of the recent therapeutic developments for treating these disorders will not only inform but will also inspire furthe...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8635(05)70145-5

    authors: Van Laborde S,Scher RK

    更新日期:2000-01-01 00:00:00

  • Advanced laboratory techniques at the Armed Forces Institute of Pathology applicable to diagnosis and research in dermatology.

    abstract::The Armed Forces Institute of Pathology (AFIP) is well known for providing expert pathology in many specialties and educational courses for civilian and military personnel. Some of the departments at the AFIP have also developed expertise in various advanced laboratory techniques for diagnosis and research that are ap...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8635(05)70074-7

    authors: Skelton HG,O'Leary TJ,Hilyard EJ,Smith KJ

    更新日期:1999-01-01 00:00:00

  • Other Chemotherapeutic Agents in Cutaneous T-Cell Lymphoma.

    abstract::Traditional chemotherapies, interleukins, phosphorylase inhibitors, and proteasome inhibitors are important therapies available to patients with cutaneous T-cell lymphoma (CTCL). Traditional chemotherapies, both in combination and as single agents, are commonly used in relapsed, refractory CTCLs that behave in an aggr...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.det.2015.05.012

    authors: Chung CG,Poligone B

    更新日期:2015-10-01 00:00:00

  • Mohs micrographic surgery technique.

    abstract::This article provides a protocol for the systematic approach to the technique of Mohs micrographic surgery. Each step, from tumor excision and tissue mapping, to specimen processing and histologic interpretation, through wound closure and postoperative management, is covered. The advantages of Mohs surgery over other ...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.det.2011.02.002

    authors: Benedetto PX,Poblete-Lopez C

    更新日期:2011-04-01 00:00:00

  • Cyanoacrylates for skin closure.

    abstract::Cyanoacrylates (CAs) were not widely adopted for medical use until recently because of lingering concerns regarding the initial tissue toxicities of the short-chain CAs. The medium-chain CAs, primarily butyl-cyanoacrylate, have been widely used in Europe and Canada for several decades and have gone a long way in dispe...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.det.2004.09.003

    authors: Eaglstein WH,Sullivan T

    更新日期:2005-04-01 00:00:00

  • Oral manifestations in the epidermolysis bullosa spectrum.

    abstract::The craniofacial and oral manifestations of the different epidermolysis bullosa (EB) types vary markedly in character and severity depending largely on the EB type. The tissues affected and the phenotypes displayed are closely related to the specific abnormal or absent proteins resulting from the causative genetic mut...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.det.2009.10.022

    authors: Wright JT

    更新日期:2010-01-01 00:00:00

  • Microlipoinjection and autologous collagen.

    abstract::There has been a resurgence over the past decade of microlipoinjection. Adipose tissue has proved to be a safe and effective filler substance for subcutaneous defects. More recently, lipocytic dermal augmentation, or autologous collagen, has been used to correct dermal defects. ...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Pinski KS,Coleman WP 3rd

    更新日期:1995-04-01 00:00:00

  • Systemic retinoid therapy.

    abstract::Systemic retinoids represent a growing armamentarium in the treatment of a wide range of skin disorders and malignancies. Although these drugs can have substantial toxicities, their wise use can result in safe and efficacious therapy that can alter dramatically the lives of individuals with severe skin disorders. ...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8635(05)70237-0

    authors: DiGiovanna JJ

    更新日期:2001-01-01 00:00:00

  • Clinical manifestations of varicella-zoster virus infection.

    abstract::Infections by VZV, the virus that causes chickenpox and herpes zoster, usually are diagnosed by the classic clinical presentations. In immunocompromised patients, however, the atypical presentation can make the diagnosis more challenging. Although varicella typically follows an uncomplicated course in children, adults...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8635(01)00012-2

    authors: Chen TM,George S,Woodruff CA,Hsu S

    更新日期:2002-04-01 00:00:00

  • Tissue effects of and host response to human papillomavirus infection.

    abstract::Human papillomaviruses are a heterogeneous group of DNA tumor viruses associated with hyperplastic (warts, condylomata), dysplastic (CIN and VIN), and malignant lesions (carcinomas) of squamous epithelium. Each HPV type is preferentially associated with specific clinical lesions and has an anatomic site preference for...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Jenson AB,Kurman RJ,Lancaster WD

    更新日期:1991-04-01 00:00:00

  • Dermabrasion.

    abstract::This article provides an overview of the resurfacing technique of dermabrasion. Preoperative consultation, perioperative medications, postoperative management, common complications, and reasonable outcome expectations are all described in detail. A description of proper technique, intraoperative equipment, and an appr...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章

    doi:10.1016/s0733-8635(05)70284-9

    authors: Harmon CB

    更新日期:2001-07-01 00:00:00

  • Chloracne. Clinical manifestations and etiology.

    abstract::Chloracne is a rare but important acneiform eruption often associated with the ingestion of chlorinated phenolic agents such as dioxins with subsequent toxicity from these chemicals. Clinically, chloracne can be distinguished from acne vulgaris by the distribution and appearance of the lesions and by taking a detailed...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Zugerman C

    更新日期:1990-01-01 00:00:00

  • Follicle trauma and the role of the dissecting microscope in hair transplantation. A multicenter study.

    abstract::Use of the dissecting stereomicroscope during hair transplant graft dissection has been advocated as a means of reducing hair follicle transection and improving graft growth. The study evaluated the prevalence of hair follicle transection in grafts prepared with and without the dissecting stereomicroscope. Approximate...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,多中心研究

    doi:10.1016/s0733-8635(05)70089-9

    authors: Cooley JE,Vogel JE

    更新日期:1999-04-01 00:00:00

  • Vasculitis.

    abstract::Vasculitis may be defined as damage to blood vessels induced by pathologic processes, resulting in compromise of function of the organ in which the blood vessels reside. A large number of syndromes and disease processes exist in which vasculitis plays a key role. Selected vasculitic syndromes of special interest to de...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Lawley TJ,Kubota Y

    更新日期:1990-10-01 00:00:00

  • Contact allergy to Phacelia spp. (Hydrophyllaceae).

    abstract::Six persons involved with cultivation trials of Phacelia spp. developed a contact allergy to certain plants of this species. Geranyl(hydro)quinone and related substances, including the geranylhydroquinone geroquinol (INN), which has been introduced as a radioprotective agent, are potent allergens and probably are more...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章

    doi:

    authors: Ippen H

    更新日期:1990-01-01 00:00:00

  • Idiopathic gingivostomatitis.

    abstract::Atypical gingivostomatitis is recognized by a combination of clinical findings, a sharply marginated, deep red edematous quality to the attached gingiva, angular cheilitis, and a sore red tongue. Unfortunately, there are no general laboratory tests that are diagnostic of the condition, although biopsy of the gingiva s...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Perry HO

    更新日期:1987-10-01 00:00:00

  • Diagnostic applications of nail clippings.

    abstract::"Nail clipping is a simple technique for diagnosis of several nail unit dermatoses. This article summarizes the practical approach, utility, and histologic findings of a nail clipping in evaluation of onychomycosis, nail unit psoriasis, onychomatricoma, subungual hematoma, melanonychia, and nail cosmetics, and the for...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.det.2014.12.011

    authors: Stephen S,Tosti A,Rubin AI

    更新日期:2015-04-01 00:00:00

  • Screening for melanoma.

    abstract::This article describes major screening studies of the past two decades, discusses the evidence-based screening recommendations, highlights the need to screen high-risk and previously unscreened populations, and concludes with suggestions for risk assessment and physician-nurse training in the skin cancer examination. ...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8635(02)00034-7

    authors: Geller AC

    更新日期:2002-10-01 00:00:00

  • Laser therapy of the skin. A review of principles and applications.

    abstract::Advances in laser technology now permit the physician to provide an effective form of treatment for a large variety of cutaneous disorders for which no previous therapy or only poor forms of therapy previously existed. Additional refinements in both laser instruments and treatment techniques are certain to have a prof...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章

    doi:

    authors: Bailin PL,Ratz JL,Wheeland RG

    更新日期:1987-04-01 00:00:00

  • Toward a human papillomavirus vaccine.

    abstract::Much progress has been made over the past 10 years with regard to development of a vaccine active against HPV. Successful protection has been achieved in animal models using species-specific papillomaviruses; however, HPV diversity may delay the development of successful HPV vaccines, especially those designed as ther...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章

    doi:10.1016/s0733-8635(05)70056-5

    authors: Rowen D,Lacey C

    更新日期:1998-10-01 00:00:00

  • Pemphigus.

    abstract::Pemphigus is an autoimmune intraepithelial blistering disease of the skin and mucous membranes that is characterized in part by the presence of circulating IgG autoantibodies. These autoantibodies, which have been shown to be pathogenic, bind to complexes on the keratinocyte cell surface and have been utilized to esta...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Korman NJ

    更新日期:1990-10-01 00:00:00

  • The wisdom of Henry M. Lewis.

    abstract::This article is a tribute to clinician Henry M. Lewis. The author shares practical therapeutic pearls developed and used over the years by Dr. Lewis. ...

    journal_title:Dermatologic clinics

    pub_type: 传,历史文章,杂志文章

    doi:

    authors: Tkach JR

    更新日期:1989-01-01 00:00:00

  • Evaluation of patients with photodermatoses.

    abstract::The systematic evaluation of photosensitive patients involves a comprehensive history, physical examination, phototesting, and, if necessary, photopatch testing and laboratory evaluation. Polymorphous light eruption, chronic actinic dermatitis, solar urticaria, and photosensitivity secondary to systemic medications ar...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.det.2014.03.006

    authors: Choi D,Kannan S,Lim HW

    更新日期:2014-07-01 00:00:00

  • Dermatologic side effects of psychopharmacologic agents.

    abstract::Exanthematous eruptions, urticaria, photosensitivity, pigmentary problems, acne, alopecia, fixed drug eruptions, and lichenoid reactions are the most common dermatologic side effects associated with the administration of psychopharmacologic agents. The cutaneous findings associated with the various eruptions and the m...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8635(05)70378-8

    authors: Garnis-Jones S

    更新日期:1996-07-01 00:00:00

  • Gardner's syndrome.

    abstract::Gardner's syndrome is an autosomal dominant genodermatosis. Familial polyposis of the colon, osteomas, and cutaneous epidermoid cysts are characteristic features. Colon cancer will develop in all affected individuals unless prophylactic colectomy is performed. The follow-up and management of patients with Gardner's sy...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Perniciaro C

    更新日期:1995-01-01 00:00:00

  • Oral manifestations of genodermatoses.

    abstract::Many genodermatoses have distinct oral features that may help identify or confirm a genetic diagnosis. Oral features of the disorders described here are summarized in Table 1. These conditions provide clear examples of rapid progress in the field of genetic technology relevant to patient care. Less than a decade ago, ...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章

    doi:10.1016/s0733-8635(02)00082-7

    authors: Hand JL,Rogers RS 3rd

    更新日期:2003-01-01 00:00:00

  • The use of topical therapies to treat onychomycosis.

    abstract::The management of onychomycosis using topical agents has improved with the introduction of ciclopirox and amorolfine nail lacquers; other topical agents may be less effective. The combination of a nail lacquer with an oral antifungal agent may further improve efficacy rates in certain clinical presentations (eg, among...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8635(03)00025-1

    authors: Gupta AK,Ryder JE,Baran R

    更新日期:2003-07-01 00:00:00

  • The histologic spectrum of the reactive inflammatory vascular dermatoses.

    abstract::The varied histopathology of the reactive inflammatory vascular dermatoses requires close cooperation between the clinician and the pathologist. This article presents an overview of the histology of this group of dermatoses, including the figurate erythemas, the pigmented purpuric eruptions, urticaria and urticarial v...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章

    doi:

    authors: Solomon AR Jr

    更新日期:1985-01-01 00:00:00

  • Recent developments in antifungal therapy.

    abstract::There have been many advances during the past few years relating to the treatment of superficial fungal infections. This article focuses on recent developments, particularly in oral therapy, but in topical therapy as well. First, the newer agents (especially fluconazole, itraconazole, and terbinafine) are reviewed, an...

    journal_title:Dermatologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8635(05)70337-5

    authors: Lesher JL Jr

    更新日期:1996-01-01 00:00:00