Abstract:
:The Israeli population is characterized by unique demographic features including high genetic homogeneity within many closed communities. As a consequence the molecular epidemiology of epidermolysis bullosa differs markedly in this country and surrounding areas from that reported in the Western world.
journal_name
Dermatol Clinjournal_title
Dermatologic clinicsauthors
Sprecher Edoi
10.1016/j.det.2010.02.019subject
Has Abstractpub_date
2010-04-01 00:00:00pages
429-30, xvissue
2eissn
0733-8635issn
1558-0520pii
S0733-8635(10)00035-5journal_volume
28pub_type
杂志文章,评审abstract::Vasculitis may be defined as damage to blood vessels induced by pathologic processes, resulting in compromise of function of the organ in which the blood vessels reside. A large number of syndromes and disease processes exist in which vasculitis plays a key role. Selected vasculitic syndromes of special interest to de...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1990-10-01 00:00:00
abstract::Ocular melanomas are the most common intraocular malignancy in adults. The majority of ocular melanomas are choroidal melanomas. These tumors can be difficult to diagnose, especially when they are small. Documented growth of a lesion on serial examinations is the most important clinical feature favoring the diagnosis ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1992-10-01 00:00:00
abstract::Large defects may at first appear to be too big to close in a side-to-side fashion. Certain wounds and situations may call for healing with second intent. Undermining and pulley sutures are very helpful in bringing together wound edges of certain large openings. Partial closures may decrease the tendency to exert unwa...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/s0733-8635(05)70294-1
更新日期:2001-07-01 00:00:00
abstract::Contact dermatitis in the United States poses a significant public health concern. This article provides a definition of contact dermatitis and its associated risk factors. The authors discuss the epidemiology of occupational contact dermatitis including its incidence and prevalence, and describe how estimates are cal...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2011.08.004
更新日期:2012-01-01 00:00:00
abstract::Many lesions that appear in the oral cavity manifest as a nodule or swelling. A particular lesion may have the clinical characteristics of several entities, and a differential diagnosis should be generated, with a final diagnosis reached by microscopic examination. This article discusses and shows the clinical feature...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70362-4
更新日期:1996-04-01 00:00:00
abstract::Photoprotection as it pertains to hair is not a common topic addressed by the dermatologist. Hair is nonliving and requires no protection from ultraviolet (UV) radiation because carcinogenesis of the hair shaft itself is not possible. If hair proteins are altered by sun exposure, damaged hair can be removed and replac...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/j.det.2005.08.006
更新日期:2006-01-01 00:00:00
abstract::The anatomic region influences the dermoscopic features of different lesions. In this article, the particular characteristics of the scalp, mucosal membranes, and lesions located on the milk line are explained. In histopathology, the benign melanocytic lesions in these locations are also named nevi of special sites, c...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2013.07.003
更新日期:2013-10-01 00:00:00
abstract::The term pyoderma encompasses a variety of distinct entities including impetigo (bullous and nonbullous), erysipelas, cellulitis, folliculitis, and staphylococcal scalded skin syndrome. Treatment of pyodermas centers around wound care and appropriate antibiotic selection. Triphenylmethane dyes, such as gentian violet,...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2010.08.009
更新日期:2011-01-01 00:00:00
abstract::One of the basic principles in the investigation of suspected contact dermatitis is always to test with the patient's "own" product or chemical, the one to which he or she was actually exposed. An equally basic second principle is not to rely solely on a positive test reaction. The author discusses a case of contact d...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Porphyria cutanea tarda is a photocutaneous syndrome characterized clinically by cutaneous fragility, bullae, hypertrichosis, pigmentary changes, and sclerodermoid plaques and characterized biochemically by hepatic overproduction and storage of excessive amounts of porphyrins. Porphyria cutanea tarda, the most common ...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1986-04-01 00:00:00
abstract::Skin diseases, including chemical burns, are the most frequently reported of all occupational illnesses. More than 90 per cent of work-related dermatologic problems are contact dermatitis, and there is rarely anything about the location and appearance of these lesions to differentiate clearly from a dermatitis of nono...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::Objectively evaluating disease activity in autoimmune bullous disease (AIBD) is important in terms of the clinical assessment of patients and as an outcome measure for clinical trials. Measures need to be general enough to capture the issues specific to each of the bullous dermatoses but specific enough to capture any...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2011.03.015
更新日期:2011-07-01 00:00:00
abstract::This article discusses ways to recognize and manage lymphomas and pseudolymphomas associated with drug exposure. Over the last 30 years, the classification of pseudolymphomas and lymphomas has undergone significant change, especially following the application of sophisticated immunostaining and gene rearrangement anal...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2007.01.008
更新日期:2007-04-01 00:00:00
abstract::Treatment of autoimmune patients can be challenging and rewarding. These patients often remain undiagnosed for prolonged periods of time or underdiagnosed without immunologic confirmation, resulting in significant morbidity. The most important principle in management of autoimmune bullous disease is to halt blistering...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2016.02.001
更新日期:2016-07-01 00:00:00
abstract::The Armed Forces Institute of Pathology (AFIP) is well known for providing expert pathology in many specialties and educational courses for civilian and military personnel. Some of the departments at the AFIP have also developed expertise in various advanced laboratory techniques for diagnosis and research that are ap...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70074-7
更新日期:1999-01-01 00:00:00
abstract::Surgery for skin cancer is a major part of clinical dermatology, and the largest single component of dermatologic surgery practice. In general, residency training in dermatology provides comprehensive training in the theory and practice of skin cancer surgery. Practicing dermatologists are similarly expert in this are...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2016.02.012
更新日期:2016-07-01 00:00:00
abstract::If one looks at the development of most drugs, it becomes evident that an extended period of time is necessary before the proper use and full range of activities of the drug in treating human disease become apparent. In many cases, initial treatment failures are due to faulty expectations as well as inadequate dosing ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1993-10-01 00:00:00
abstract::In the past decade, midface rejuvenation has matured to allow experienced surgeons to address this area as part of a total facial rejuvenation. Procedures have advanced as successive generations of surgeons have improved understanding of this complex anatomic area. Midface rejuvenation is fraught with perils, however,...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2005.03.006
更新日期:2005-07-01 00:00:00
abstract::Hepatic itch remains among the most agonizing symptoms for affected patients and a major clinical challenge for physicians. Pruritus may occur in almost all liver diseases, particularly those with cholestatic features. Hepatic itch arises irrespective of the severity of the underlying liver disease or extent of choles...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2018.02.008
更新日期:2018-07-01 00:00:00
abstract::Acne vulgaris alters the normal skin physiology, impairing stratum corneum and transepidermal water loss. A male's normal skin physiologic state is different than a female's and may have implications when choosing treatment when the skin is altered in a disease state. Transepidermal water loss, pH, and sebum productio...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2015.11.007
更新日期:2016-04-01 00:00:00
abstract::I would like to stress that there seem to be three subpopulations of neural crest-derived melanocytes in the body that can be functionally and morphologically distinguished: the cutaneous melanocytes, which continuously synthesize small melanosomes to be transferred to keratinocytes; the uveal melanocytes, which synth...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1988-04-01 00:00:00
abstract::Systemic retinoids represent a growing armamentarium in the treatment of a wide range of skin disorders and malignancies. Although these drugs can have substantial toxicities, their wise use can result in safe and efficacious therapy that can alter dramatically the lives of individuals with severe skin disorders. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70237-0
更新日期:2001-01-01 00:00:00
abstract::Papulosquamous eruptions are the most frequently seen cutaneous manifestations of human immunodeficiency virus (HIV) infection. Especially common and useful in making a diagnosis of HIV infection are seborrheic dermatitis, xerosis or ichthyosis, and a pruritic or papular eruption. There is some evidence from transgeni...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1991-07-01 00:00:00
abstract::Osteoporosis affects more than 75 million people in the United States, Asia, and Europe. Osteoporosis results from a combination of genetic and environmental factors that contribute to peak bone mass and the rate of bone loss. These factors include medications, diet, race, sex, lifestyle, and physical activity. The ma...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2006.01.013
更新日期:2006-04-01 00:00:00
abstract::The diagnosis of lymphoma currently relies on a combination of clinical, routine histopathologic, and immunohistochemical studies, sometimes supplemented by other special techniques such as flow cytometry, DNA analysis, and gene rearrangement study. This review considers the practical diagnosis of cutaneous lymphoma, ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract::Liposuction is the most popular cosmetic surgical procedure performed in men. Aside from traditional liposuction using the tumescent technique, several energy-assisted liposuction technologies have emerged and been proven safe and particularly beneficial for the male patient demographic. The differences in fat distrib...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2017.09.010
更新日期:2018-01-01 00:00:00
abstract::UV erythema or sunburn is a common sequela of modern man's pursuit of leisure activities. The dermatologist is frequently confronted with this painful cutaneous inflammatory response. The pathogenesis of sunburn is examined in terms of individual genetic sensitivity, environmental exposure, spectral variability, and t...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1986-04-01 00:00:00
abstract::Human papillomavirus infections of the skin and anogenital tract are common. The association of these viruses with neoplasia, particularly of the anogenital tract, has stimulated efforts to devise practical methods of detection and typing of HPV. Although experimental diagnostic tests are available, they are, for the ...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1991-04-01 00:00:00
abstract::Countries in the so-called "Western" world, especially in Europe, witnessed a dramatic change in ethnic backgrounds of their populations starting in the last decennia of the last century. This had repercussions on various aspects of our society, including medical practice. In dermatology for instance, pigmentary disor...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2007.04.005
更新日期:2007-07-01 00:00:00
abstract::This article describes that the diagnosis of melanoma has improved with such tools as epiluminescence microscopy. There remain, however, a number of unusual types of melanoma that are difficult to diagnose by virtue of their atypical or subtle morphology. The prognosis of these melanomas is often worse than for their ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(02)00036-0
更新日期:2002-10-01 00:00:00