Abstract:
:In order to impart antibacterial properties to microfibrous electrospun materials from styrene/maleic anhydride copolymers, quaternized chitosan derivatives (QCh) containing alkyl substituents of different chain lengths are covalently attached to the mats. A complete inhibition of the growth of bacteria, S. aureus (Gram-positive) and E. coli (Gram-negative), for a contact time of 30–120 min or a decrease of the bacterial titer by 2–3 log units is observed depending on the quaternization degree, the chain length of the alkyl substituent, and the molar mass of QCh. The modified mats are also effective in suppressing the adhesion of pathogenic S. aureus bacteria.
journal_name
Macromol Bioscijournal_title
Macromolecular bioscienceauthors
Ignatova M,Petkova Z,Manolova N,Markova N,Rashkov Idoi
10.1002/mabi.201100178subject
Has Abstractpub_date
2012-01-01 00:00:00pages
104-15issue
1eissn
1616-5187issn
1616-5195journal_volume
12pub_type
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