Thermohydrogel Containing Melanin for Photothermal Cancer Therapy.

abstract：:Poly(vinyl alcohol)-pyrene-anti-metadherin (PVA-Py-(Anti-MTDH)), a novel antibody based water soluble probe containing both fluorescent and target sites in the structure for in vitro imaging of breast cancer cells is reported here. Since breast cancer cells have an excess of MDTH protein expressed on the surface, a PV...

journal_title：Macromolecular bioscience

authors： Medine EI,Odaci D,Gacal BN,Gacal B,Sakarya S,Unak P,Timur S,Yagci Y

更新日期：2010-06-11 00:00:00

abstract：:[Image: see text] Oligosaccharides at cell surfaces are known to play a critical role in many biological processes such as biorecognition, interactions between cells and with artificial surfaces, immune response, infection and inflammation. In order to facilitate studies of the role of sugars, an increasing number of ...

journal_title：Macromolecular bioscience

authors： Coullerez G,Seeberger PH,Textor M

更新日期：2006-08-07 00:00:00

abstract：:In search for effective non-viral gene vectors for the delivery of siRNA, a copolymer was designed and synthesized by grafting hydrophobic poly(gamma-benzyl L-glutamate) segment (PBLG) to hyperbranched polyethylenimine (PEI-PBLG). PEI-PBLG could efficiently deliver siRNA to cells to silence the targeted gene. Markedly...

journal_title：Macromolecular bioscience

authors： Chen J,Tian H,Guo Z,Xia J,Kano A,Maruyama A,Jing X,Chen X

更新日期：2009-12-08 00:00:00

abstract：:S-Layer proteins are an example of bionanostructures that can be exploited in nanofabrication. In addition to their ordered structure, the ability to self-assembly is a key feature that makes them a promising technological tool. Here, in vitro self-assembly kinetics of SpbA was investigated, and found that it occurs a...

journal_title：Macromolecular bioscience

authors： Teixeira LM,Strickland A,Mark SS,Bergkvist M,Sierra-Sastre Y,Batt CA

更新日期：2010-02-11 00:00:00

abstract：:The nanostructure of a biomaterial surface has strong influence on cell behavior. The migration of cells on nanostructured surfaces, however, has not been investigated so far. In this study, we used PCL/PEG diblock copolymers as model surfaces to examine the effect of nanoislands on migration of different cells, inclu...

journal_title：Macromolecular bioscience

authors： Hsu SH,Tang CM,Chiu JJ,Liao TC,Lin CC,Iwata H

更新日期：2007-04-10 00:00:00

abstract：:An antioxidant microgel with both glutathione peroxidase (GPx) and superoxide dismutase (SOD) activities is reported. Using computational design and genetic engineering methods, the main catalytic components of GPx are fabricated onto the surface of ferritin. The resulting seleno-ferritin (Se-Fn) monomers can self-ass...

journal_title：Macromolecular bioscience

authors： Gao Y,Hou C,Zhou L,Zhang D,Zhang C,Miao L,Wang L,Dong Z,Luo Q,Liu J

更新日期：2013-06-01 00:00:00

abstract：:Vascular grafts are used to bypass damaged or diseased blood vessels. Bacterial cellulose (BC) has been studied for use as an off-the-shelf graft. Herein, we present a novel, cost-effective, method for the production of small caliber BC grafts with minimal processing or requirements. The morphology of the graft wall p...

journal_title：Macromolecular bioscience

authors： Leitão AF,Faria MA,Faustino AM,Moreira R,Mela P,Loureiro L,Silva I,Gama M

更新日期：2016-01-01 00:00:00

abstract：:The present review is aimed at elucidating relatively new aspects of mucoadhesion/mucus interaction and related phenomena that emerged from a Mucoadhesion workshop held in Munster on 2-3 September 2015 as a satellite event of the ICCC 13th-EUCHIS 12th. After a brief outline of the new issues, the focus is on mucus des...

journal_title：Macromolecular bioscience

authors： Mackie AR,Goycoolea FM,Menchicchi B,Caramella CM,Saporito F,Lee S,Stephansen K,Chronakis IS,Hiorth M,Adamczak M,Waldner M,Nielsen HM,Marcelloni L

更新日期：2017-08-01 00:00:00

abstract：:The effect of doping graphene oxide (GO) and reduced graphene oxide (rGO) into poly(ε-caprolactone) (PCL) membranes prepared by solvent induced phase separation is evaluated in terms of nanomaterial distribution and compatibility with neural stem cell growth and functional differentiation. Raman spectra analyses demon...

journal_title：Macromolecular bioscience

authors： Sánchez-González S,Diban N,Bianchi F,Ye H,Urtiaga A

更新日期：2018-11-01 00:00:00

abstract：:The repair of large crushed or sectioned segments of peripheral nerves remains a challenge in regenerative medicine due to the complexity of the biological environment and the lack of proper biomaterials and architecture to foster reconstruction. Traditionally such reconstruction is only achieved by using fresh human ...

journal_title：Macromolecular bioscience

authors： Belanger K,Dinis TM,Taourirt S,Vidal G,Kaplan DL,Egles C

更新日期：2016-04-01 00:00:00

abstract：:Numerous hydrogel-based culture systems are used to create in vitro model for prevascularization. Hydrogels used to induce a microenvironment conducive to microvessel formation are typically soft and fast degradable, but often suffer from maintaining a lasting perfusable channel in vitro. Here, a dual hydrogel system ...

journal_title：Macromolecular bioscience

authors： Kim S,Pan CC,Yang YP

更新日期：2020-10-01 00:00:00

abstract：:Living materials are created through the embedding of live, whole cells into a matrix that can house and sustain the viability of the encapsulated cells. Through the immobilization of these cells, their bioactivity can be harnessed for applications such as bioreactors for the production of high-value chemicals. While ...

journal_title：Macromolecular bioscience

authors： Johnston TG,Fillman JP,Priks H,Butelmann T,Tamm T,Kumar R,Lahtvee PJ,Nelson A

更新日期：2020-08-01 00:00:00

abstract：:The efficient internalization of TGF-beta inhibitor-loaded polyelectrolyte capsules and particles is studied in two HCC cell lines. Two polyelectrolyte pairs (biocompatible but not degradable and biodegradable crosslinked with gluteraldehyde) are employed for coating. The capsules are characterized by SEM. LY is succe...

journal_title：Macromolecular bioscience

authors： Baldassarre F,Vergaro V,Scarlino F,De Santis F,Lucarelli G,Torre AD,Ciccarella G,Rinaldi R,Giannelli G,Leporatti S

更新日期：2012-05-01 00:00:00

abstract：:A combination of hard sphere and high internal phase emulsion templating gives a platform for synthesizing hierarchically porous polymers with a unique topology exhibiting interconnected spherical features on multiple levels. Polymeric spheres are fused by thermal sintering to create a 3D monolithic structure while an...

journal_title：Macromolecular bioscience

authors： Paljevac M,Gradišnik L,Lipovšek S,Maver U,Kotek J,Krajnc P

更新日期：2018-02-01 00:00:00

abstract：:Given the major structural role phosphodiesters play in the organism it is surprising they have not been more widely adopted as a building block in sophisticated biomimetic hydrogels and other biomaterials. The potential benefits are substantial: phosphoester-based materials show excellent compatibility with blood, ce...

journal_title：Macromolecular bioscience

authors： Dera R,Diliën H,Billen B,Gagliardi M,Rahimi N,Van Den Akker NMS,Molin DGM,Grandfils C,Adriaensens P,Guedens W,Cleij TJ

更新日期：2019-07-01 00:00:00

abstract：:Polymeric nanostructures obtained through self-assembly of reduction-sensitive amphiphilic triblock copolymers were investigated as potential drug delivery systems. The characteristic feature of these polymers is their cleavable disulfide bond in the center of the hydrophobic block. Therefore, the triblock copolymers ...

journal_title：Macromolecular bioscience

authors： Toughraï S,Malinova V,Masciadri R,Menon S,Tanner P,Palivan C,Bruns N,Meier W

更新日期：2015-04-01 00:00:00

abstract：:Synthetic resins have been extensively employed by artists in their works of art, e.g. as paint binders, or by conservators for conservation treatments, e.g. as stone consolidants and protectives. It is generally thought that synthetic resins are less prone to chemical, physical and biological deterioration than other...

journal_title：Macromolecular bioscience

authors： Cappitelli F,Zanardini E,Sorlini C

更新日期：2004-04-19 00:00:00

abstract：:The role viscoelasticity in fibrotic disease progression is an emerging area of interest. Here, a fast-relaxing hydrogel system is exploited to investigate potential crosstalk between calcium signaling and mechanotransduction. Poly(ethylene glycol) (PEG) hydrogels containing boronate and triazole crosslinkers are synt...

journal_title：Macromolecular bioscience

authors： Ma H,Macdougall LJ,GonzalezRodriguez A,Schroeder ME,Batan D,Weiss RM,Anseth KS

更新日期：2020-12-01 00:00:00

abstract：:The aggregative behaviors of hydroxypropylcellulose (HPC) molecules in aqueous solution and on substrates have been observed by employing laser light scattering (LLS) and, after deposition on a mica surface, atomic force microscopy (AFM). LLS studies showed that the HPC molecules formed large aggregates through self-a...

journal_title：Macromolecular bioscience

authors： Yan L,Lin W,Bangal PR

更新日期：2006-07-14 00:00:00

abstract：:In this study, PLLA nanofibers are fabricated by electrospinning and their surfaces are modified by laminin/chitosan (LN/CS) polyelectrolyte multilayer. Surface C/N ratio determined by XPS analysis quantitatively indicates of discrete coating layers on the nanofibers. The amount of LN deposited sustainably increases w...

journal_title：Macromolecular bioscience

authors： He L,Tang S,Prabhakaran MP,Liao S,Tian L,Zhang Y,Xue W,Ramakrishna S

更新日期：2013-11-01 00:00:00

abstract：:Polylaminin (polyLM) is a polymerized form of the extracellular matrix protein laminin obtained upon pH acidification. Here microscopy and spectroscopic tools are used to study the cell compatibility and the structural stability of polyLM, aiming at establishing its robustness as a biopolymer for therapeutic use. Poly...

journal_title：Macromolecular bioscience

authors： Freire E,Barroso MM,Klier RN,Coelho-Sampaio T

更新日期：2012-01-01 00:00:00

abstract：:Formulation of docetaxel (DOC), a hydrophobic anticancer drug, was successfully achieved in poly(gamma-benzyl L-glutamate)-block-hyaluronan polymersomes using a simple and reproducible nanoprecipitation method. The prepared DOC loaded polymersomes (PolyDOC) was stable either in solution or in a lyophilized form, and s...

journal_title：Macromolecular bioscience

authors： Upadhyay KK,Bhatt AN,Castro E,Mishra AK,Chuttani K,Dwarakanath BS,Schatz C,Le Meins JF,Misra A,Lecommandoux S

更新日期：2010-05-14 00:00:00

abstract：:Novel water-insoluble, and reduction-responsive nonwoven scaffolds were fabricated from gamma-PGA and tested in cell culture. An electrospinning method was developed to produce scaffolds of fibers with diameters of 0.05-0.5 microm. Crosslinking of the fibers with cystamine in the presence of EDC resulted in water-inso...

journal_title：Macromolecular bioscience

authors： Yoshida H,Klinkhammer K,Matsusaki M,Möller M,Klee D,Akashi M

更新日期：2009-06-11 00:00:00

abstract：:A simple continuous flow wet-spinning method to achieve mechanical reinforcement of the two oppositely charged biopolymers chitosan and gellan gum is described. The mechanical properties of these biopolymers are influenced by the order of addition. Using a facile method for mechanical reinforcement of gellan gum/chito...

journal_title：Macromolecular bioscience

authors： Granero AJ,Razal JM,Wallace GG,in het Panhuis M

更新日期：2009-04-08 00:00:00

abstract：:Cell-free approaches to in situ tissue engineering require materials that are mechanically stable and are able to control cell-adhesive behavior upon implantation. Here, the development of mechanically stable grafts with non-cell adhesive properties via a mix-and-match approach using ureido-pyrimidinone (UPy)-modified...

journal_title：Macromolecular bioscience

authors： van Almen GC,Talacua H,Ippel BD,Mollet BB,Ramaekers M,Simonet M,Smits AI,Bouten CV,Kluin J,Dankers PY

更新日期：2016-03-01 00:00:00

abstract：:The enzymatic transformation into an oligomer was carried out with the objective of developing the chemical recycling of bacterial polyesters. Poly(R-3-hydroxyalkanoate)s (PHAs), such as poly[(R-3-hydroxybutyrate)-co-12%(R-3-hydroxyhexanoate)] and poly[(R-3-hydroxybutyrate)-co-12%(R-3-hydroxyvalerate)], were degraded ...

journal_title：Macromolecular bioscience

authors： Kaihara S,Osanai Y,Nishikawa K,Toshima K,Doi Y,Matsumura S

更新日期：2005-07-14 00:00:00

abstract：:This paper presents the analysis of the volume phase transition of ionic thermo-sensitive hydrogels to thermal stimulus through mathematical modelling. The model is termed the multi-effect-coupling thermal-stimulus (MECtherm) model and it considers the effects of multi-phases and multi-physics. Its application to stea...

journal_title：Macromolecular bioscience

authors： Li H,Wang X,Wang Z,Lam KY

更新日期：2005-09-16 00:00:00

abstract：:The aim of this study is to design a novel two-component hybrid scaffold using the fibrin/alginate porous hydrogel Smart Matrix combined to a backing layer of plasma polymerized polydimethylsiloxane (Sil) membrane to make the fibrin-based dermal scaffold more robust for the treatment of the clinically challenging pres...

journal_title：Macromolecular bioscience

authors： Sharma V,Kohli N,Moulding D,Afolabi H,Hook L,Mason C,García-Gareta E

更新日期：2017-11-01 00:00:00

abstract：:The aim of this study is to establish the safe and effective ocular delivery system of therapeutic small interfering RNA (siRNA) in corneal neovascularization therapy. The major hurdle present in siRNA-based corneal neovascularization (CNV) therapy is severe cytotoxicity caused by repetitive drug treatment. A reducibl...

journal_title：Macromolecular bioscience

authors： Han H,Son S,Son S,Kim N,Yhee JY,Lee JH,Choi JS,Joo CK,Lee H,Lee D,Kim WJ,Kim SH,Kwon IC,Kim H,Kim K

更新日期：2016-11-01 00:00:00

abstract：:Bleeding complications usually cause significant morbidity and mortality in civilian and military populations. In clinical application, hemostatic sponges, gauzes, hydrogel, and bandages are widely used as the traditional effective hemostatic products for hemorrhage. However, the traditional hemostatic devices or agen...

journal_title：Macromolecular bioscience

authors： Chen Y,Wu L,Li P,Hao X,Yang X,Xi G,Liu W,Feng Y,He H,Shi C

更新日期：2020-04-01 00:00:00