Abstract:
:p53 is a key tumor suppressor protein that has numerous functions. Its primary mode of action has generally been ascribed to the induction of cell-cycle arrest, apoptosis, or senescence upon stress. Li et al. challenge this dogma with evidence that all three of these programs are dispensable for p53's tumor suppressive role.
journal_name
Celljournal_title
Cellauthors
Hock AK,Vousden KHdoi
10.1016/j.cell.2012.05.024subject
Has Abstractpub_date
2012-06-08 00:00:00pages
1183-5issue
6eissn
0092-8674issn
1097-4172pii
S0092-8674(12)00636-8journal_volume
149pub_type
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