Abstract:
:The synthesis of 13C-labeled steroid hormones is reviewed. Two general approaches are highlighted: partial synthesis in which part of the steroid nucleus is replaced with 13C-labeled synthons, and total synthesis. Examples from both approaches, leading to (3-(3)C)-, (4-(13)C)-, (3,4-(13)C2)-, and (1,2,3,4-(13)C4)- labeled steroid hormones (e.g., testosterone, estradiol, progesterone, and cortisol), are presented.
journal_name
Steroidsjournal_title
Steroidsauthors
Zomer G,Stavenuiter JFdoi
10.1016/0039-128x(90)90012-zsubject
Has Abstractpub_date
1990-10-01 00:00:00pages
440-2issue
10eissn
0039-128Xissn
1878-5867pii
0039-128X(90)90012-Zjournal_volume
55pub_type
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