Abstract:
:A facile method for the synthesis of a series of new steroidal 3-thioxamides from the 3-oxo compound, variously substituted at the 17 position, is described. The "one pot" reaction, using Lawesson's reagent (4-methoxyphenylthionophosphine sulphide dimer) in dichloromethane solution, gives the desired compounds with a high degree of chemoselectivity, in good yields (> 80%).
journal_name
Steroidsjournal_title
Steroidsauthors
Grisenti P,Magni A,Manzocchi A,Ferraboschi Pdoi
10.1016/s0039-128x(97)00003-2subject
Has Abstractpub_date
1997-06-01 00:00:00pages
504-6issue
6eissn
0039-128Xissn
1878-5867pii
S0039-128X(97)00003-2journal_volume
62pub_type
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