Abstract:
:16alpha-hydroxydehydroepiandrosterone was for the first time detected in human seminal plasma by using a combination of extraction, solvent partition, HPLC separation and final quantification by GC-MS as pentafluorobenzyloxime trimethylsilyl ether derivative in SIM mode. Three effective mass fragments m/z 266, 356 and 446 were followed. The concentration of 16alpha-hydroxydehydroepiandrosterone amounted in average 1.06 nmol/l, being lower but close to- the product of concurrent DHEA metabolism, 7-hydroxydehydroepiandrosterone isomers, found recently in seminal plasma.
journal_name
Steroidsjournal_title
Steroidsauthors
Hert J,Hill M,Hampl Rdoi
10.1016/j.steroids.2004.05.017subject
Has Abstractpub_date
2004-10-01 00:00:00pages
773-7issue
11-12eissn
0039-128Xissn
1878-5867pii
S0039-128X(04)00145-Xjournal_volume
69pub_type
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