Distinguishing logopenic from semantic & nonfluent variant primary progressive aphasia: Patterns of linguistic and behavioral correlations.

abstract：UNLABELLED:Neuropathologic change underlying primary progressive aphasia (PPA) most commonly includes one of the frontotemporal lobar degenerations, such as FTLD-tau or FTLD-ubiquitin. The next most frequent etiology of PPA is Alzheimer's disease (AD). We describe 5 subjects with clinical diagnoses of semantic dementia...

journal_title：Neurocase

authors： Chow TW,Varpetian A,Moss T,Vinters HV,Marquez S,Miller C

更新日期：2010-02-01 00:00:00

abstract：:Chediak-Higashi syndrome (CHS) is a rare autosomal disorder characterized by immunodeficiency, albinism, and progressive neurologic abnormalities. While survivors of the childhood-onset disease are known to exhibit learning disabilities and neuropsychiatric disorders followed by middle-age dementia, we lack detailed d...

journal_title：Neurocase

authors： Yliranta A,Mäkinen J

更新日期：2020-12-09 00:00:00

abstract：:Gerstmann-Sträussler-Scheinker syndrome is a rare autosomal dominant disease caused by a mutation in the prion gene, usually manifesting as progressive ataxia with late cognitive decline. A 44-year-old woman with a positive family history developed early personality and behavior changes, followed by paresthesias and a...

journal_title：Neurocase

authors： Rusina R,Fiala J,Holada K,Matějčková M,Nováková J,Ampapa R,Koukolík F,Matěj R

更新日期：2013-01-01 00:00:00

abstract：:The current study investigated the effects of easy versus difficult math on event-related potentials as a function of self-esteem in 28 undergraduate students. First, it was found that participants responded much more rapidly to an easy task. Second, the amplitude of P2 (150-300 ms) was more positive amplified in low ...

journal_title：Neurocase

authors： Yang J,Zhao R,Zhang Q,Pruessner JC

更新日期：2013-01-01 00:00:00

abstract：:By studying an enigmatic condition called, "calendar synesthesia", we explored the elusive boundary between perception, visual imagery, and the manner in which we construct an internal mental calendar by mapping time-sequences onto spatial maps. We use a series of demonstrations to establish that these calendars act m...

journal_title：Neurocase

authors： Ramachandran VS,Chunharas C,Marcus Z

更新日期：2020-02-01 00:00:00

abstract：:Regressive behavior is a known sequela after severe traumatic brain injury (TBI). However, prolonged "infantile-like" behavior has received little attention in the literature, suggesting that this is a rare phenomenon. It is typically characterized by long-lasting childish, extremely dependent, and sometimes aggressiv...

journal_title：Neurocase

authors： Heled E,Sverdlik A,Agranov E

更新日期：2014-01-01 00:00:00

abstract：:It has been suggested that formal thought disorder, the incoherent speech of schizophrenia, may involve a language disturbance among other abnormalities, or even be a form of dysphasia. Six patients with and seven without formal thought disorder were evaluated on an aphasia test battery. Spontaneous speech was also an...

journal_title：Neurocase

authors： Oh TM,McCarthy RA,McKenna PJ

更新日期：2002-01-01 00:00:00

abstract：:The concreteness effect occurs in both normal and language-disordered populations. Research suggests that abstract and concrete concepts elicit differing neural activation patterns in healthy young adults, but this is undocumented in persons with aphasia (PWA). Three PWA and three age-matched controls were scanned usi...

journal_title：Neurocase

authors： Sandberg C,Kiran S

更新日期：2014-08-01 00:00:00

abstract：:Cerebral lesions are held to induce plastic changes of the brain. Less well established, however, is how much space-occupying brain lesions may only displace functional representations. In a 66-year-old man we show, by means of functional magnetic resonance imaging and transcranial magnetic stimulation, a profound dis...

journal_title：Neurocase

authors： Nickel J,Jörgens S,Bussfeld P,Seitz RJ

更新日期：2007-10-01 00:00:00

abstract：:We assessed visuospatial abilities in PCA. Sequential display of two simple geometric figures enhanced detection and discrimination relative to simultaneous display (Exps 1 & 2). Comparing edges of a single object enhanced discrimination relative to comparing edges of two separate objects, consistent with object-based...

journal_title：Neurocase

authors： Fernandez-Duque D,Black SE

更新日期：2020-04-01 00:00:00

abstract：:Topographical disorientation is usually described in patients who have lost the ability to orient themselves as a consequence of acquired focal brain damage. Here, we describe the case of a 20-year-old woman with a congenital brain malformation who has never been able to orient herself within the environment. We addre...

journal_title：Neurocase

authors： Iaria G,Incoccia C,Piccardi L,Nico D,Sabatini U,Guariglia C

更新日期：2005-12-01 00:00:00

abstract：:A hexanucleotide repeat expansion in the chromosome 9 open reading frame 72 (C9ORF72) gene was recently discovered as the cause underlying frontotemporal degeneration (FTD) and/or amyotrophic lateral sclerosis (ALS) linked to chromosome 9 (c9FTD/ALS). In this atypical case of c9FTD/ALS, the proband presented with amne...

journal_title：Neurocase

authors： Adeli A,Savica R,Lowe VJ,Vemuri P,Knopman DS,Dejesus-Hernandez M,Rademakers R,Fields JA,Crum BA,Jack CR,Petersen RC,Boeve BF

更新日期：2014-01-01 00:00:00

abstract：:Physical symptoms of myoclonus dystonia due to epsilon-sarcoglycan mutations are well documented; however, the progression of neuropsychiatric and cognitive symptoms remains unclear. We present a case of a 34-year-old woman with early childhood onset of myoclonic jerks, dystonic posture and developmental delay due to ...

journal_title：Neurocase

authors： Multani N,Moro E,Lang A,Zurowski M,Duff Canning S,Tartaglia MC

更新日期：2016-01-01 00:00:00

abstract：:A 75 year-old man had a two-year history of progressive memory loss, trouble with finances and getting lost. On examination, he scored 16/30 in MoCA test, noticeably impaired on the attentional tasks. His screening bloodtests werenormal. Brain imaging revealed hippocampal atrophy and bilaterallarge areas of leukoaraio...

journal_title：Neurocase

authors： Pisanuwongrak K,Julayanont P,Heilman KM

更新日期：2020-08-01 00:00:00

abstract：:We hypothesized that distinct acute right hemisphere lesions disrupt separate components of valuation and emotional response to winning and losing money and of emotional empathy in observing a partner win or lose money. We measured skin conductance response (SCR) and ratings of emotions when acute right hemisphere str...

journal_title：Neurocase

authors： Kim EH,Chien JH,Liu CC,Oishi K,Oishi K,Sebastian R,Demsky C,Lenz F,Hillis AE

更新日期：2017-02-01 00:00:00

abstract：:This paper reports the case of a patient, M.P., who developed delusion of inanimate doubles, without Capgras syndrome, after traumatic brain injury. His delusional symptoms were studied longitudinally and the cognitive impairments associated with delusion were investigated. Data suggest that M.P. did 'perceive' the ac...

journal_title：Neurocase

authors： Abbate C,Trimarchi PD,Salvi GP,Quarenghi AM,Vergani C,Luzzatti C

更新日期：2012-01-01 00:00:00

abstract：:Opsoclonus myoclonus ataxia (OMA) is a rare neurological disorder (incidence = approximately 1/5 million) primarily associated with involuntary conjugate saccadic eye movements, involuntary muscle jerks, cerebellar ataxia, and neuropsychological impairments. Unfortunately, there is limited published data regarding the...

journal_title：Neurocase

authors： Smith ML,Thawani N,Johnstone B,Stucky R

更新日期：2010-08-01 00:00:00

abstract：:Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective treatment for Parkinson's disease, but can lead to adverse effects including psychiatric disturbance. Little is known about the risk factors and treatment options for such effects. Here, we describe a patient who reproducibly developed stimu...

journal_title：Neurocase

authors： Schilbach L,Weiss PH,Kuhn J,Timmermann L,Klosterkötter J,Huff W

更新日期：2012-01-01 00:00:00

abstract：:BVR was 77 years old when he sustained a large posterior cerebral artery territory infarct. Medical, cognitive and functional data collected on four occasions over 10 years initially revealed circumscribed neurological signs, no functional or cognitive deficits. BVR became significantly impaired only after two other s...

journal_title：Neurocase

authors： Piguet O,Bennett HP,Waite LM,Kril JJ,Creasey H,Anthony Broe G,Halliday GM

更新日期：2006-04-01 00:00:00

abstract：:A deficit of declarative memory is a common sequela after a hypoxic episode. While the role of gray matter changes (i.e., atrophy of hippocampal formation) as mainly responsible for memory loss has been emphasized, the role of the white matter damage has so far been neglected. The present study was aimed at evaluating...

journal_title：Neurocase

authors： Di Paola M,Moscatelli A,Bigler ED,Caltagirone C,Carlesimo GA

更新日期：2011-02-01 00:00:00

abstract：:Previous research suggests that the noradrenergic system modulates flexibility of access to the lexical-semantic network, with propranolol benefiting normal subjects in lexical-semantic problem solving tasks. Patients with Broca's aphasia with anomia have impaired ability to access appropriate verbal output for a give...

journal_title：Neurocase

authors： Beversdorf DQ,Sharma UK,Phillips NN,Notestine MA,Slivka AP,Friedman NM,Schneider SL,Nagaraja HN,Hillier A

更新日期：2007-08-01 00:00:00

abstract：:The noradrenergic system modulates performance on tasks dependent on semantic and associative network flexibility (NF) in individuals without neurodevelopmental diagnoses in experiments using a beta-adrenergic antagonist, propranolol. Some studies suggest drugs decreasing noradrenergic activity are beneficial in ASD. ...

journal_title：Neurocase

authors： Beversdorf DQ,Carpenter AL,Miller RF,Cios JS,Hillier A

更新日期：2008-01-01 00:00:00

abstract：:The clinical distinction between autism spectrum disorders (ASD), also called pervasive developmental disorders (PDD), and schizophrenia is often difficult to make. Here we describe a case of an adult patient presenting with a diagnosis of schizophrenia based on a history of functional deterioration and presumed perse...

journal_title：Neurocase

authors： Crivelli B,Rocca P

更新日期：2013-01-01 00:00:00

abstract：:Depression following stroke (PSD) affects up to 33% of patients and is associated with increased mortality. Antidepressant drugs have several side effects; therefore novel treatments are needed. Transcranial direct current stimulation (tDCS) has induced mood and cognitive gain in several neuropsychiatric conditions bu...

journal_title：Neurocase

authors： Bueno VF,Brunoni AR,Boggio PS,Bensenor IM,Fregni F

更新日期：2011-08-01 00:00:00

abstract：:In a previous report, we presented longitudinal clinical, cognitive and anatomical data of a right-handed woman, whose clinical picture evolved from progressive nonfluent aphasia with apraxia of speech to corticobasal syndrome (CBS) in the last stage of the disease. The patient died at age 57 and pathological examinat...

journal_title：Neurocase

authors： Sánchez-Valle R,Forman MS,Miller BL,Gorno-Tempini ML

更新日期：2006-12-01 00:00:00

abstract：:Neglect dyslexia is a reading disorder often associated with right-sided brain lesions. In reading single words, errors are mostly substitutions or omissions of letters that occupy the left-sided positions. Typically, these errors have been thought to depend on a single mechanism. Conversely, we propose that they are ...

journal_title：Neurocase

authors： Martelli M,Arduino LS,Daini R

更新日期：2011-01-01 00:00:00

abstract：:Patients with memory disorders have severely restricted learning and memory. For instance, patients with anterograde amnesia can learn motor procedures and retain some restricted ability to learn new words and factual information. However, such learning is inflexible and frequently inaccessible to conscious awareness....

journal_title：Neurocase

authors： Olson IR,Berryhill ME,Drowos DB,Brown L,Chatterjee A

更新日期：2010-06-01 00:00:00

abstract：:In large early cortical lesions, one of the most devastating consequences is the impaired motor dexterity of the contralateral limb. We present the case of an 8-year-old girl with a large left hemispherical porencephaly. Unlike previous reports, the girl exhibited high dexterity of the contralateral hand with preserve...

journal_title：Neurocase

authors： Weber B,Fliessbach K,Elger CE

更新日期：2006-10-01 00:00:00

abstract：:Debates about the role of language in human thinking are increasingly prominent in the cognitive sciences. There are claims that certain forms of reasoning can only be performed through access to the resources of the language faculty. In particular, a component of social cognition involving the representation of the m...

journal_title：Neurocase

authors： Varley R,Siegal M,Want SC

更新日期：2001-01-01 00:00:00

abstract：:The purpose of this study was to determine if differential reading and spelling mechanisms were involved in a Japanese patient with aphasia. In our case, the patient scored low on all of the administered reading tasks, suggesting that both the reading lexical and non-lexical routes were impaired. In contrast, his writ...

journal_title：Neurocase

authors： Hashimoto K,Uno A

更新日期：2016-06-01 00:00:00