The GGGGCC repeat expansion in C9ORF72 in a case with discordant clinical and FDG-PET findings: PET trumps syndrome.

abstract：:We investigated the neural systems that support number processing in a patient (JL) who had damage to the left ventral occipito-temporal cortex (LvOT). JL had severely impaired written word recognition but he was remarkably accurate in number tasks, albeit slower than normal. This suggests LvOT activation is necessary...

journal_title：Neurocase

authors： Cappelletti M,Leff AP,Price CJ

更新日期：2012-01-01 00:00:00

abstract：:It is a common finding in tests of false recognition that amnesic patients recognize fewer related lures than healthy controls, and this has led to assumptions that gist memory is damaged in these patients (Schacter, Verfaellie, & Anes, 1997, Neuropsychology, 11; Schacter, Verfaellie, Anes, & Racine, 1998, Journal of ...

journal_title：Neurocase

authors： Nissan J,Abrahams S,Sala SD

更新日期：2013-01-01 00:00:00

abstract：:The psychoses of epilepsy are well recognized complications of seizure disorders, diagnosed easily from the history. However, in the absence of recognized seizures, the diagnosis can be challenging. We present a 27-year-old female, who suffered a treatment refractory psychosis for 6 years. She did not report, or dis...

journal_title：Neurocase

authors： Needham E,Hamelijnck J

更新日期：2012-01-01 00:00:00

abstract：:Psychiatric disorders represent common comorbidities in epileptic patients. Sometimes anxiety is part of the ictal semiology, especially during seizures arising from/involving frontal or temporal lobes. We describe a patient with focal epilepsy and recurrent hyperkinetic seizures who also presented prolonged episodes ...

journal_title：Neurocase

authors： Albini M,Morano A,Fattouch J,Fanella M,Avorio F,Basili LM,Cerulli Irelli E,Manfredi M,Giallonardo AT,Di Bonaventura C

更新日期：2020-04-01 00:00:00

abstract：:We report a 4-year-old child with severe semi-lobar holoprosencephaly (HPE) not expected to survive after birth. Magnetic resonance imaging (MRI) revealed agenesis of the corpus callosum, absence of the third ventricle, fused thalami and basal ganglia. To investigate sensory function, visual, auditory and somatosensor...

journal_title：Neurocase

authors： Liasis A,Hildebrand D,Clark C,Katz X,Gunny R,Stieltjes B,Taylor D

更新日期：2009-01-01 00:00:00

abstract：:To further understand the nature of the visual-spatial representations required for successful acquisition of written language skills, we investigated the written language abilities of two individuals with Williams syndrome (WS) a developmental genetic disorder in which the presence of severe visual-spatial developmen...

journal_title：Neurocase

authors： Dessalegn B,Landau B,Rapp B

更新日期：2013-08-01 00:00:00

abstract：:Frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U) is one of the most common pathological findings associated with the clinical FTLD syndromes. However, molecular characterization with genetic sequencing and protein expression techniques are recognizing many new subtypes for FTLDs. FTLDs are...

journal_title：Neurocase

authors： Farmer JG,Crain BJ,Harris BT,Turner RS

更新日期：2013-01-01 00:00:00

abstract：:This article describes an investigation into the residual writing skills of a severely dysgraphic patient (DA). We found that they were powerfully influenced by a number of lexical variables (lexicality, frequency, imageability, length and geminates). His error pattern was characterized by semantic, lexical, substitut...

journal_title：Neurocase

authors： Cipolotti L,Bird CM,Glasspool DW,Shallice T

更新日期：2004-12-01 00:00:00

abstract：:It has been suggested that formal thought disorder, the incoherent speech of schizophrenia, may involve a language disturbance among other abnormalities, or even be a form of dysphasia. Six patients with and seven without formal thought disorder were evaluated on an aphasia test battery. Spontaneous speech was also an...

journal_title：Neurocase

authors： Oh TM,McCarthy RA,McKenna PJ

更新日期：2002-01-01 00:00:00

abstract：:Depression following stroke (PSD) affects up to 33% of patients and is associated with increased mortality. Antidepressant drugs have several side effects; therefore novel treatments are needed. Transcranial direct current stimulation (tDCS) has induced mood and cognitive gain in several neuropsychiatric conditions bu...

journal_title：Neurocase

authors： Bueno VF,Brunoni AR,Boggio PS,Bensenor IM,Fregni F

更新日期：2011-08-01 00:00:00

abstract：:Vocal emblems, such as shh and brr, are speech sounds that have linguistic and nonlinguistic features; thus, it is unclear how they are processed in the brain. Five adult dextral individuals with left-brain damage and moderate-severe Wernicke's aphasia, five adult dextral individuals with right-brain damage, and five ...

journal_title：Neurocase

authors： Neumann-Werth Y,Levy ES,Obler LK

更新日期：2013-01-01 00:00:00

abstract：:We examined the relations between selection for perception and selection for action in a patient FK, with bilateral damage to his temporal and medial frontal cortices. The task required a simple grasp response to a common object (a cup) in the presence of a distractor (another cup). The target was cued by colour or lo...

journal_title：Neurocase

authors： Boutsen L,Humphreys GW

更新日期：2003-06-01 00:00:00

abstract：:Dissociative identity disorder (DID) is probably the most disputed of psychiatric diagnoses and of psychological forensic evaluations in the legal arena. The iatrogenic proponents assert that DID phenomena originate from psychotherapeutic treatment while traumagenic proponents state that DID develops after severe and ...

journal_title：Neurocase

authors： Reinders AA

更新日期：2008-01-01 00:00:00

abstract：:A 75 year-old man had a two-year history of progressive memory loss, trouble with finances and getting lost. On examination, he scored 16/30 in MoCA test, noticeably impaired on the attentional tasks. His screening bloodtests werenormal. Brain imaging revealed hippocampal atrophy and bilaterallarge areas of leukoaraio...

journal_title：Neurocase

authors： Pisanuwongrak K,Julayanont P,Heilman KM

更新日期：2020-08-01 00:00:00

abstract：:A quantitative assessment of a distortion involving the left side of space, both in two-dimensional (drawing), and three-dimensional (modeling), visuo-constructional tasks is reported in a patient with a right temporoparieto-occipital lesion, and left hemianopia, without visuospatial neglect. In drawing and clay model...

journal_title：Neurocase

authors： Rode G,Revol P,Rossetti Y,Vallar G

更新日期：2008-01-01 00:00:00

abstract：:Patients with Parkinson's disease (PD) are often impaired when performing motor acts and in the acquisition of new motor skills. However, the role of dopamine in developing plans for skill acquisition is unclear. To assess the role of dopamine on the planning of actions, we tested 12 PD and 12 matched normal participa...

journal_title：Neurocase

authors： Hanna-Pladdy B,Heilman KM

更新日期：2010-04-01 00:00:00

abstract：:A striking special ability in arranging picture stories was reported in an Asperger child (C.M.) showing an exceptional performance on Wechsler picture arrangement subtest. Neuropsychological examination did not disclose visuoperceptual and spatial defects, or working memory, attention and executive disorders, but rev...

journal_title：Neurocase

authors： Conson M,Salzano S,Grossi D

更新日期：2011-08-01 00:00:00

abstract：:This case study describes the neurocognitive presentation of a child with identified genetic abnormalities of trisomy 6 and monosomy 21 who was evaluated as part of a standard medical protocol for cochlear implantation following diagnosis of profound sensorineural hearing loss. This child received neurocognitive testi...

journal_title：Neurocase

authors： Katzenstein JM,Oghalai JS,Tonini R,Baker D,Haymond J,Caudle SE

更新日期：2009-01-01 00:00:00

abstract：:Subject GSI presents with a graphemic buffer deficit following a massive left fronto-parietal lesion. His errors involved essentially only consonants (98.2%). However, he always spelled correctly the first consonant in a string, and produced steadily increasing numbers of errors on the following consonants, while alwa...

journal_title：Neurocase

authors： Miceli G,Capasso R,Benvegnù B,Caramazza A

更新日期：2004-04-01 00:00:00

abstract：:We have seen a patient with a profound, isolated, and quite selective deficit in proverb interpretation-aproverbia. The patient presented to us after an anoxic brain injury with aproverbia. Interestingly, the aproverbia appeared to be premorbid to the presenting event. Furthermore, the patient had no brain lesion that...

journal_title：Neurocase

authors： Brown C,Smith-Benjamin S,Patira R,Altschuler EL

更新日期：2016-06-01 00:00:00

abstract：:Children (aged 9-12) training in an El Sistema-inspired program (OrKidstra) and a matched comparison group participated in an auditory Go/No-Go task while event-related potentials (ERPs) were recorded. Entire-sweep waveform patterns correlated with known ERP peaks associated with executive and other cognitive function...

journal_title：Neurocase

authors： Hedayati N,Schibli K,D'Angiulli A

更新日期：2016-12-01 00:00:00

abstract：:Synaesthesia is often triggered by numbers, although it is conceivable that different aspects of numerical representation are responsible for different variants of synaesthesia. For individuals with "higher synaesthesia" it is assumed that number meaning (or numerosity) is responsible for the elicitation of synaesthet...

journal_title：Neurocase

authors： Ward J,Sagiv N

更新日期：2007-04-01 00:00:00

abstract：:The clinical distinction between autism spectrum disorders (ASD), also called pervasive developmental disorders (PDD), and schizophrenia is often difficult to make. Here we describe a case of an adult patient presenting with a diagnosis of schizophrenia based on a history of functional deterioration and presumed perse...

journal_title：Neurocase

authors： Crivelli B,Rocca P

更新日期：2013-01-01 00:00:00

abstract：:In this paper we report the results of a longitudinal study which examined memory for a single routine activity of daily living in people with dementia of the Alzheimer type. We assessed memory in a natural setting, visiting volunteers in their homes. We video-taped performance on the selected task and analysed the re...

journal_title：Neurocase

authors： Rusted J,Sheppard L

更新日期：2002-01-01 00:00:00

abstract：UNLABELLED:Neuropathologic change underlying primary progressive aphasia (PPA) most commonly includes one of the frontotemporal lobar degenerations, such as FTLD-tau or FTLD-ubiquitin. The next most frequent etiology of PPA is Alzheimer's disease (AD). We describe 5 subjects with clinical diagnoses of semantic dementia...

journal_title：Neurocase

authors： Chow TW,Varpetian A,Moss T,Vinters HV,Marquez S,Miller C

更新日期：2010-02-01 00:00:00

abstract：:Patients with memory disorders have severely restricted learning and memory. For instance, patients with anterograde amnesia can learn motor procedures and retain some restricted ability to learn new words and factual information. However, such learning is inflexible and frequently inaccessible to conscious awareness....

journal_title：Neurocase

authors： Olson IR,Berryhill ME,Drowos DB,Brown L,Chatterjee A

更新日期：2010-06-01 00:00:00

abstract：:A 57-year-old male with no family history was diagnosed with semantic dementia. He also showed some unusual cognitive features such as episodic memory and executive dysfunctions, spatial disorientation, and dyscalculia. Rapidly progressive cognitive and physical decline occurred. About 1.5 years later, he developed cl...

journal_title：Neurocase

authors： Clerc MT,Deprez M,Leuba G,Lhermitte B,Lopez U,von Gunten A

更新日期：2015-02-01 00:00:00

abstract：:The noradrenergic system modulates performance on tasks dependent on semantic and associative network flexibility (NF) in individuals without neurodevelopmental diagnoses in experiments using a beta-adrenergic antagonist, propranolol. Some studies suggest drugs decreasing noradrenergic activity are beneficial in ASD. ...

journal_title：Neurocase

authors： Beversdorf DQ,Carpenter AL,Miller RF,Cios JS,Hillier A

更新日期：2008-01-01 00:00:00

abstract：:For functional neuroimaging studies of stuttering, two challenges are (1) the elicitation of naturally stuttered versus fluent speech and (2) the separation of activation associated with abnormal motor execution from activation that reflects the cognitive substrates of stuttering. This paper reports on a proof-of-conc...

journal_title：Neurocase

authors： den Ouden DB,Montgomery A,Adams C

更新日期：2014-08-01 00:00:00

abstract：:We observed a 59-year-old right-handed man with an infarction in his right-middle cerebral artery that included the parietal lobe, who abnormally manipulated mental images in the horizontal direction, resulting in calculation disturbances. Three years later, the patient suffered an infarction in the left parietal lobe...

journal_title：Neurocase

authors： Asada T,Takayama Y,Oita J,Fukuyama H

更新日期：2014-04-01 00:00:00