Effect of propranolol on naming in chronic Broca's aphasia with anomia.

Abstract:

:Previous research suggests that the noradrenergic system modulates flexibility of access to the lexical-semantic network, with propranolol benefiting normal subjects in lexical-semantic problem solving tasks. Patients with Broca's aphasia with anomia have impaired ability to access appropriate verbal output for a given visual stimulus in a naming task. Therefore, we tested naming in a pilot study of chronic Broca's aphasia patients with anomia after propranolol and after placebo in a double-blinded crossover manner. Naming was better after propranolol than after placebo, suggesting a potential benefit from propranolol in chronic Broca's aphasia with anomia. Larger follow-up studies are necessary to further investigate this effect.

journal_name

Neurocase

journal_title

Neurocase

authors

Beversdorf DQ,Sharma UK,Phillips NN,Notestine MA,Slivka AP,Friedman NM,Schneider SL,Nagaraja HN,Hillier A

doi

10.1080/13554790701595471

subject

Has Abstract

pub_date

2007-08-01 00:00:00

pages

256-9

issue

4

eissn

1355-4794

issn

1465-3656

pii

782135949

journal_volume

13

pub_type

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