Abstract:
:Previous research suggests that the noradrenergic system modulates flexibility of access to the lexical-semantic network, with propranolol benefiting normal subjects in lexical-semantic problem solving tasks. Patients with Broca's aphasia with anomia have impaired ability to access appropriate verbal output for a given visual stimulus in a naming task. Therefore, we tested naming in a pilot study of chronic Broca's aphasia patients with anomia after propranolol and after placebo in a double-blinded crossover manner. Naming was better after propranolol than after placebo, suggesting a potential benefit from propranolol in chronic Broca's aphasia with anomia. Larger follow-up studies are necessary to further investigate this effect.
journal_name
Neurocasejournal_title
Neurocaseauthors
Beversdorf DQ,Sharma UK,Phillips NN,Notestine MA,Slivka AP,Friedman NM,Schneider SL,Nagaraja HN,Hillier Adoi
10.1080/13554790701595471subject
Has Abstractpub_date
2007-08-01 00:00:00pages
256-9issue
4eissn
1355-4794issn
1465-3656pii
782135949journal_volume
13pub_type
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