Degree of abnormality is associated with rate of change in measures of beta-amyloid, glucose metabolism and cognition in an autopsy-verified Alzheimer's disease case.

abstract：:The brain's primary motor and primary somatosensory cortices are generally viewed as functionally distinct entities. Here we show by means of magnetoencephalography with a phantom-limb patient, that movement of the phantom hand leads to a change in the response of the primary somatosensory cortex to tactile stimulatio...

journal_title：Neurocase

authors： McGeoch PD,Brang D,Huang M,Ramachandran VS

更新日期：2015-02-01 00:00:00

abstract：:Central pontine and extrapontine myelinolysis (CPEM) is a rare neurological condition usually due to rapid correction of hyponatremia. CPEM is mainly characterized by motor deficits (typically quadraparesis or extrapyramidal features) but neurobehavioral symptoms were also reported in the literature. However, very few...

journal_title：Neurocase

authors： Arciero S,Kempf C,Bernard F,Gosselin N

更新日期：2012-01-01 00:00:00

abstract：:This article describes an investigation into the residual writing skills of a severely dysgraphic patient (DA). We found that they were powerfully influenced by a number of lexical variables (lexicality, frequency, imageability, length and geminates). His error pattern was characterized by semantic, lexical, substitut...

journal_title：Neurocase

authors： Cipolotti L,Bird CM,Glasspool DW,Shallice T

更新日期：2004-12-01 00:00:00

abstract：:Previous research suggests that the noradrenergic system modulates flexibility of access to the lexical-semantic network, with propranolol benefiting normal subjects in lexical-semantic problem solving tasks. Patients with Broca's aphasia with anomia have impaired ability to access appropriate verbal output for a give...

journal_title：Neurocase

authors： Beversdorf DQ,Sharma UK,Phillips NN,Notestine MA,Slivka AP,Friedman NM,Schneider SL,Nagaraja HN,Hillier A

更新日期：2007-08-01 00:00:00

abstract：:To further understand the nature of the visual-spatial representations required for successful acquisition of written language skills, we investigated the written language abilities of two individuals with Williams syndrome (WS) a developmental genetic disorder in which the presence of severe visual-spatial developmen...

journal_title：Neurocase

authors： Dessalegn B,Landau B,Rapp B

更新日期：2013-08-01 00:00:00

abstract：:We report a case of frontotemporal dementia caused by a novel MAPT mutation (Q351R) with a remarkably long amnestic presentation mimicking familial Alzheimer's disease. Longitudinal clinical, neuropsychological and imaging data provide convergent evidence for predominantly bilateral anterior medial temporal lobe invol...

journal_title：Neurocase

authors： Liang Y,Gordon E,Rohrer J,Downey L,de Silva R,Jäger HR,Nicholas J,Modat M,Cardoso MJ,Mahoney C,Warren J,Rossor M,Fox N,Caine D

更新日期：2014-01-01 00:00:00

abstract：:An investigation of non-verbal auditory comprehension in two patients with global aphasia following stroke is reported. The primary aim of the investigation was to establish whether refractory access disorders can affect non-verbal input modalities. All previous reports of refractoriness, a cognitive syndrome characte...

journal_title：Neurocase

authors： Crutch SJ,Warrington EK

更新日期：2008-01-01 00:00:00

abstract：:In this paper we report the results of a longitudinal study which examined memory for a single routine activity of daily living in people with dementia of the Alzheimer type. We assessed memory in a natural setting, visiting volunteers in their homes. We video-taped performance on the selected task and analysed the re...

journal_title：Neurocase

authors： Rusted J,Sheppard L

更新日期：2002-01-01 00:00:00

abstract：:BVR was 77 years old when he sustained a large posterior cerebral artery territory infarct. Medical, cognitive and functional data collected on four occasions over 10 years initially revealed circumscribed neurological signs, no functional or cognitive deficits. BVR became significantly impaired only after two other s...

journal_title：Neurocase

authors： Piguet O,Bennett HP,Waite LM,Kril JJ,Creasey H,Anthony Broe G,Halliday GM

更新日期：2006-04-01 00:00:00

abstract：:It is a common finding in tests of false recognition that amnesic patients recognize fewer related lures than healthy controls, and this has led to assumptions that gist memory is damaged in these patients (Schacter, Verfaellie, & Anes, 1997, Neuropsychology, 11; Schacter, Verfaellie, Anes, & Racine, 1998, Journal of ...

journal_title：Neurocase

authors： Nissan J,Abrahams S,Sala SD

更新日期：2013-01-01 00:00:00

abstract：:Gerstmann-Sträussler-Scheinker syndrome is a rare autosomal dominant disease caused by a mutation in the prion gene, usually manifesting as progressive ataxia with late cognitive decline. A 44-year-old woman with a positive family history developed early personality and behavior changes, followed by paresthesias and a...

journal_title：Neurocase

authors： Rusina R,Fiala J,Holada K,Matějčková M,Nováková J,Ampapa R,Koukolík F,Matěj R

更新日期：2013-01-01 00:00:00

abstract：:We assessed visuospatial abilities in PCA. Sequential display of two simple geometric figures enhanced detection and discrimination relative to simultaneous display (Exps 1 & 2). Comparing edges of a single object enhanced discrimination relative to comparing edges of two separate objects, consistent with object-based...

journal_title：Neurocase

authors： Fernandez-Duque D,Black SE

更新日期：2020-04-01 00:00:00

abstract：:We observed a 59-year-old right-handed man with an infarction in his right-middle cerebral artery that included the parietal lobe, who abnormally manipulated mental images in the horizontal direction, resulting in calculation disturbances. Three years later, the patient suffered an infarction in the left parietal lobe...

journal_title：Neurocase

authors： Asada T,Takayama Y,Oita J,Fukuyama H

更新日期：2014-04-01 00:00:00

abstract：:An adult female complained of enlargement of right eyes in other people. Diffusion-weighted imaging detected an abnormal high-intensity area in the region from the splenium of the corpus callosum to the major forceps on the right side. The patient reported that right eyes appeared larger in size, which suggested proso...

journal_title：Neurocase

authors： Ogawa K,Akimoto T,Takahashi K,Hara M,Morita A,Kamei S,Nakajima H,Fujishiro M,Suzuki Y,Soma M,Shikata E,Futamura A,Kawamura M

更新日期：2020-10-01 00:00:00

abstract：:The psychoses of epilepsy are well recognized complications of seizure disorders, diagnosed easily from the history. However, in the absence of recognized seizures, the diagnosis can be challenging. We present a 27-year-old female, who suffered a treatment refractory psychosis for 6 years. She did not report, or dis...

journal_title：Neurocase

authors： Needham E,Hamelijnck J

更新日期：2012-01-01 00:00:00

abstract：:We report a patient presenting with clinical features of logopenic variant primary progressive aphasia (lvPPA) who was later diagnosed with probable dementia with Lewy bodies. LvPPA is a neurodegenerative disease that is characterized by anomia, word-finding difficulty, impaired comprehension, and phonological errors....

journal_title：Neurocase

authors： Boes S,Botha H,Machulda M,Lowe V,Graff-Radford J,Whitwell JL,Utianski RL,Duffy JR,Josephs KA

更新日期：2020-10-01 00:00:00

abstract：:Studies of patients with brain lesions have demonstrated that language and praxis are mediated by dissociable networks. However, language has the capacity to influence the selection of purposeful actions. The abilities to use language and to program purposeful movements are often mediated by networks that have anatomi...

journal_title：Neurocase

authors： Falchook AD,Burtis DB,Acosta LM,Salazar L,Shushrutha Hedna V,Khanna AY,Heilman KM

更新日期：2014-06-01 00:00:00

abstract：:The semantic variant of primary progressive aphasia (PPA-S) is characterized by impairments in confrontation naming and single word comprehension. Although episodic memory may be relatively spared, there can be impairment in verbal learning tasks. We report a patient with PPA-S and impaired verbal learning who was tes...

journal_title：Neurocase

authors： Milano NJ,Williamson JB,Heilman KM

更新日期：2015-01-01 00:00:00

abstract：:Neurophysiological and functional brain imaging studies suggest the importance of dorsolateral area 9/46 for modality-independent working memory. However, the behavioural manifestations following isolated damage to this area have not been clearly outlined. Here, we describe the dramatic derangement of pragmatic memory...

journal_title：Neurocase

authors： Ptak R,Schnider A

更新日期：2004-02-01 00:00:00

abstract：:Children (aged 9-12) training in an El Sistema-inspired program (OrKidstra) and a matched comparison group participated in an auditory Go/No-Go task while event-related potentials (ERPs) were recorded. Entire-sweep waveform patterns correlated with known ERP peaks associated with executive and other cognitive function...

journal_title：Neurocase

authors： Hedayati N,Schibli K,D'Angiulli A

更新日期：2016-12-01 00:00:00

abstract：:This case study describes the neurocognitive presentation of a child with identified genetic abnormalities of trisomy 6 and monosomy 21 who was evaluated as part of a standard medical protocol for cochlear implantation following diagnosis of profound sensorineural hearing loss. This child received neurocognitive testi...

journal_title：Neurocase

authors： Katzenstein JM,Oghalai JS,Tonini R,Baker D,Haymond J,Caudle SE

更新日期：2009-01-01 00:00:00

abstract：:A 75 year-old man had a two-year history of progressive memory loss, trouble with finances and getting lost. On examination, he scored 16/30 in MoCA test, noticeably impaired on the attentional tasks. His screening bloodtests werenormal. Brain imaging revealed hippocampal atrophy and bilaterallarge areas of leukoaraio...

journal_title：Neurocase

authors： Pisanuwongrak K,Julayanont P,Heilman KM

更新日期：2020-08-01 00:00:00

abstract：:Dissociative identity disorder (DID) is probably the most disputed of psychiatric diagnoses and of psychological forensic evaluations in the legal arena. The iatrogenic proponents assert that DID phenomena originate from psychotherapeutic treatment while traumagenic proponents state that DID develops after severe and ...

journal_title：Neurocase

authors： Reinders AA

更新日期：2008-01-01 00:00:00

abstract：:Recent lesion studies have shown that left hemisphere lesions often give rise to frank sign language aphasias in deaf signers, whereas right hemisphere lesions do not, suggesting similar patterns of hemispheric asymmetry for signed and spoken language. We present here a case of a left-handed, deaf, life-long signer wh...

journal_title：Neurocase

authors： Pickell H,Klima E,Love T,Kritchevsky M,Bellugi U,Hickok G

更新日期：2005-06-01 00:00:00

abstract：:Monocular patching might improve perceptual-attentional, not motor-intentional deficits in a patient with chronic post-stroke left spatial neglect. Performing a line-cancellation task, his omission errors were associated with a perceptual-attentional 'where' deficit, while perseverative errors were associated with 'ai...

journal_title：Neurocase

authors： Khurshid S,Longin H,Crucian GP,Barrett AM

更新日期：2009-08-01 00:00:00

abstract：:The purpose of the present study was to investigate differences in brain activation with functional magnetic resonance imaging (fMRI) during imagery of painful and non-painful 'finger movements' and 'hand positioning' in a subject with an amputated arm. The subject was a right-handed man in his mid-thirties who lost h...

journal_title：Neurocase

authors： Rosén G,Hugdahl K,Ersland L,Lundervold A,Smievoll AI,Barndon R,Sundberg H,Thomsen T,Roscher BE,Tjølsen A,Engelsen B

更新日期：2001-01-01 00:00:00

abstract：:A striking special ability in arranging picture stories was reported in an Asperger child (C.M.) showing an exceptional performance on Wechsler picture arrangement subtest. Neuropsychological examination did not disclose visuoperceptual and spatial defects, or working memory, attention and executive disorders, but rev...

journal_title：Neurocase

authors： Conson M,Salzano S,Grossi D

更新日期：2011-08-01 00:00:00

abstract：:Oculocutaneous albinism (OCA) is a group of autosomal recessive disorders characterized by impairment in the melanin synthesis. We report two siblings with OCA who presented with symptoms of autism spectrum disorder and attention deficit hyperactivity disorder (ADHD). Ocular side effects occured after methylphenidate ...

journal_title：Neurocase

authors： Ünsel Bolat G

更新日期：2020-12-01 00:00:00

abstract：:It has been suggested that formal thought disorder, the incoherent speech of schizophrenia, may involve a language disturbance among other abnormalities, or even be a form of dysphasia. Six patients with and seven without formal thought disorder were evaluated on an aphasia test battery. Spontaneous speech was also an...

journal_title：Neurocase

authors： Oh TM,McCarthy RA,McKenna PJ

更新日期：2002-01-01 00:00:00

abstract：:The current study investigated the effects of easy versus difficult math on event-related potentials as a function of self-esteem in 28 undergraduate students. First, it was found that participants responded much more rapidly to an easy task. Second, the amplitude of P2 (150-300 ms) was more positive amplified in low ...

journal_title：Neurocase

authors： Yang J,Zhao R,Zhang Q,Pruessner JC

更新日期：2013-01-01 00:00:00