Abstract:
:The semantic variant of primary progressive aphasia (PPA-S) is characterized by impairments in confrontation naming and single word comprehension. Although episodic memory may be relatively spared, there can be impairment in verbal learning tasks. We report a patient with PPA-S and impaired verbal learning who was tested to learn if when provided with semantic categories, her learning would improve. A 70-year-old right-handed woman with a 2-year history of progressive difficulties with word finding, naming, and memory was tested for language and memory deficits using the Hopkins Verbal Learning Test-Revised (HVLT-R). She was then retested with the HVLT-R after being provided with the three semantic categories to which these words belonged. Confrontation naming was impaired on the Boston Naming Test. Sentence repetition was normal. Comprehension testing with word picture matching and sentence comprehension was normal. On a test of semantic associations, Pyramids and Palm Trees, she was impaired. She was also impaired on tests of verbal learning (HVLT-R) (total: 13) but not recall. When a different version of the HVLT-R was given with the semantic categories of the words given beforehand, her scores improved (total: 26). This patient with PPA-S had an impairment of verbal learning, but not delayed recall. When given a semantic category cue beforehand, her verbal learning performance improved. This observation suggests that this patient did not spontaneously use semantic encoding. Using a semantic cueing strategy may help other patients with PPA-S improve their capacity for verbal learning.
journal_name
Neurocasejournal_title
Neurocaseauthors
Milano NJ,Williamson JB,Heilman KMdoi
10.1080/13554794.2014.894081subject
Has Abstractpub_date
2015-01-01 00:00:00pages
345-50issue
3eissn
1355-4794issn
1465-3656journal_volume
21pub_type
杂志文章相关文献
NEUROCASE文献大全abstract::The delay between cardiac arrest and brain MRI is usually extremely different in the few cerebral imaging studies assessing the affected brain areas. We report an unusual case of loss of psychic self-activation appeared immediately after a cardiac arrest in a middle age patient. The first brain MRI, one month after th...
journal_title:Neurocase
pub_type: 临床试验,杂志文章
doi:10.1080/13554794.2019.1608263
更新日期:2019-01-01 00:00:00
abstract::We examined the relations between selection for perception and selection for action in a patient FK, with bilateral damage to his temporal and medial frontal cortices. The task required a simple grasp response to a common object (a cup) in the presence of a distractor (another cup). The target was cued by colour or lo...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1076/neur.9.3.239.15556
更新日期:2003-06-01 00:00:00
abstract::Recent research revealed decreased access to semantic and associative networks in acute cocaine withdrawal. In autism, such behavioral outcomes are associated with decreased functional connectivity using functional magnetic resonance imaging. Therefore, we wished to determine whether connectivity is also decreased in ...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2011.627341
更新日期:2012-01-01 00:00:00
abstract::We report a 4-year-old child with severe semi-lobar holoprosencephaly (HPE) not expected to survive after birth. Magnetic resonance imaging (MRI) revealed agenesis of the corpus callosum, absence of the third ventricle, fused thalami and basal ganglia. To investigate sensory function, visual, auditory and somatosensor...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554790802631936
更新日期:2009-01-01 00:00:00
abstract::The psychoses of epilepsy are well recognized complications of seizure disorders, diagnosed easily from the history. However, in the absence of recognized seizures, the diagnosis can be challenging. We present a 27-year-old female, who suffered a treatment refractory psychosis for 6 years. She did not report, or dis...
journal_title:Neurocase
pub_type: 杂志文章,评审
doi:10.1080/13554794.2011.627338
更新日期:2012-01-01 00:00:00
abstract::In this paper, we adopt a neurodevelopmental stance to examining frontal variant frontotemporal dementia (fv-FTD) by using experimental procedures from the literature on the growth of social behaviour in children to examine the deficits in social reasoning which may underpin behavioural disturbance in fv-FTD. We prese...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1093/neucas/7.2.123
更新日期:2001-01-01 00:00:00
abstract:UNLABELLED:Neuropathologic change underlying primary progressive aphasia (PPA) most commonly includes one of the frontotemporal lobar degenerations, such as FTLD-tau or FTLD-ubiquitin. The next most frequent etiology of PPA is Alzheimer's disease (AD). We describe 5 subjects with clinical diagnoses of semantic dementia...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554790903193174
更新日期:2010-02-01 00:00:00
abstract::Monocular patching might improve perceptual-attentional, not motor-intentional deficits in a patient with chronic post-stroke left spatial neglect. Performing a line-cancellation task, his omission errors were associated with a perceptual-attentional 'where' deficit, while perseverative errors were associated with 'ai...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554790902776888
更新日期:2009-08-01 00:00:00
abstract::We assessed visuospatial abilities in PCA. Sequential display of two simple geometric figures enhanced detection and discrimination relative to simultaneous display (Exps 1 & 2). Comparing edges of a single object enhanced discrimination relative to comparing edges of two separate objects, consistent with object-based...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2020.1729385
更新日期:2020-04-01 00:00:00
abstract::For functional neuroimaging studies of stuttering, two challenges are (1) the elicitation of naturally stuttered versus fluent speech and (2) the separation of activation associated with abnormal motor execution from activation that reflects the cognitive substrates of stuttering. This paper reports on a proof-of-conc...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2013.791863
更新日期:2014-08-01 00:00:00
abstract::Neurodegenerative diseases are caused by aggregation of specific proteins that catalyze a cascade of changes that ultimately lead to neurodegeneration. This concept guides current diagnostic approaches, as well as clinical trials, that focus on detecting or removing amyloid or tau from the brain. The semantic variant ...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2018.1447134
更新日期:2018-04-01 00:00:00
abstract::Debates about the role of language in human thinking are increasingly prominent in the cognitive sciences. There are claims that certain forms of reasoning can only be performed through access to the resources of the language faculty. In particular, a component of social cognition involving the representation of the m...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1093/neucas/7.6.489
更新日期:2001-01-01 00:00:00
abstract::An adult female complained of enlargement of right eyes in other people. Diffusion-weighted imaging detected an abnormal high-intensity area in the region from the splenium of the corpus callosum to the major forceps on the right side. The patient reported that right eyes appeared larger in size, which suggested proso...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2020.1797819
更新日期:2020-10-01 00:00:00
abstract::An investigation of non-verbal auditory comprehension in two patients with global aphasia following stroke is reported. The primary aim of the investigation was to establish whether refractory access disorders can affect non-verbal input modalities. All previous reports of refractoriness, a cognitive syndrome characte...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554790802498955
更新日期:2008-01-01 00:00:00
abstract::This article describes an investigation into the residual writing skills of a severely dysgraphic patient (DA). We found that they were powerfully influenced by a number of lexical variables (lexicality, frequency, imageability, length and geminates). His error pattern was characterized by semantic, lexical, substitut...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554790490893995
更新日期:2004-12-01 00:00:00
abstract::A 75 year-old man had a two-year history of progressive memory loss, trouble with finances and getting lost. On examination, he scored 16/30 in MoCA test, noticeably impaired on the attentional tasks. His screening bloodtests werenormal. Brain imaging revealed hippocampal atrophy and bilaterallarge areas of leukoaraio...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2020.1769138
更新日期:2020-08-01 00:00:00
abstract::Physical symptoms of myoclonus dystonia due to epsilon-sarcoglycan mutations are well documented; however, the progression of neuropsychiatric and cognitive symptoms remains unclear. We present a case of a 34-year-old woman with early childhood onset of myoclonic jerks, dystonic posture and developmental delay due to ...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2015.1120312
更新日期:2016-01-01 00:00:00
abstract::Central pontine and extrapontine myelinolysis (CPEM) is a rare neurological condition usually due to rapid correction of hyponatremia. CPEM is mainly characterized by motor deficits (typically quadraparesis or extrapyramidal features) but neurobehavioral symptoms were also reported in the literature. However, very few...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2011.633528
更新日期:2012-01-01 00:00:00
abstract::A quantitative assessment of a distortion involving the left side of space, both in two-dimensional (drawing), and three-dimensional (modeling), visuo-constructional tasks is reported in a patient with a right temporoparieto-occipital lesion, and left hemianopia, without visuospatial neglect. In drawing and clay model...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554790802389154
更新日期:2008-01-01 00:00:00
abstract::We observed a 59-year-old right-handed man with an infarction in his right-middle cerebral artery that included the parietal lobe, who abnormally manipulated mental images in the horizontal direction, resulting in calculation disturbances. Three years later, the patient suffered an infarction in the left parietal lobe...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2012.741254
更新日期:2014-04-01 00:00:00
abstract::The purpose of this study was to determine if differential reading and spelling mechanisms were involved in a Japanese patient with aphasia. In our case, the patient scored low on all of the administered reading tasks, suggesting that both the reading lexical and non-lexical routes were impaired. In contrast, his writ...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2015.1137950
更新日期:2016-06-01 00:00:00
abstract::Dissociative identity disorder (DID) is probably the most disputed of psychiatric diagnoses and of psychological forensic evaluations in the legal arena. The iatrogenic proponents assert that DID phenomena originate from psychotherapeutic treatment while traumagenic proponents state that DID develops after severe and ...
journal_title:Neurocase
pub_type: 杂志文章,评审
doi:10.1080/13554790801992768
更新日期:2008-01-01 00:00:00
abstract::In a previous report, we presented longitudinal clinical, cognitive and anatomical data of a right-handed woman, whose clinical picture evolved from progressive nonfluent aphasia with apraxia of speech to corticobasal syndrome (CBS) in the last stage of the disease. The patient died at age 57 and pathological examinat...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554790600977218
更新日期:2006-12-01 00:00:00
abstract::Patients with memory disorders have severely restricted learning and memory. For instance, patients with anterograde amnesia can learn motor procedures and retain some restricted ability to learn new words and factual information. However, such learning is inflexible and frequently inaccessible to conscious awareness....
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554790903405701
更新日期:2010-06-01 00:00:00
abstract::The degree of abnormality and rate of change in cognitive functions, positron emission tomography Pittsburg compound B (PET PIB), and fluorodeoxyglucose (FDG) measures were studied for 8 years in an autopsy-confirmed Alzheimer's disease (AD) patient, who died 61 years old (Mini-Mental State Examination (MMSE) score 7)...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2014.979835
更新日期:2015-01-01 00:00:00
abstract::Frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U) is one of the most common pathological findings associated with the clinical FTLD syndromes. However, molecular characterization with genetic sequencing and protein expression techniques are recognizing many new subtypes for FTLDs. FTLDs are...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2011.654217
更新日期:2013-01-01 00:00:00
abstract::After a stroke involving the left occipitotemporal cortex our patient shows a word-length effect and has problems to identify letters or numbers in strings of symbols. But he is normal in identifying isolated letters and in non-verbally categorizing even complex images such as faces or natural scenes. His cortical les...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2019.1634739
更新日期:2019-10-01 00:00:00
abstract::We studied reading performance for words and for isolated letters in a pure alexic patient. She performed reasonably well when naming isolated letters but was slower in reading letters than a control subject when reaction times (RTs) were recorded. When the patient read isolated letters, RTs were slower for a subset o...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1076/neur.9.2.164.15069
更新日期:2003-04-01 00:00:00
abstract::Gerstmann-Sträussler-Scheinker syndrome is a rare autosomal dominant disease caused by a mutation in the prion gene, usually manifesting as progressive ataxia with late cognitive decline. A 44-year-old woman with a positive family history developed early personality and behavior changes, followed by paresthesias and a...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2011.654215
更新日期:2013-01-01 00:00:00
abstract::The amygdala nuclei appear to be critically implicated in emotional memory. However, in most studies, encoding and consolidation processes cannot be analyzed separately. We thus studied the verbal emotional memory in a young woman with a ganglioglioma of the left amygdala and analyzed its impact (1) on each step of th...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2015.1037843
更新日期:2016-01-01 00:00:00