Functional connectivity during language processing in acute cocaine withdrawal: a pilot study.

Abstract:

:Recent research revealed decreased access to semantic and associative networks in acute cocaine withdrawal. In autism, such behavioral outcomes are associated with decreased functional connectivity using functional magnetic resonance imaging. Therefore, we wished to determine whether connectivity is also decreased in acute cocaine withdrawal. Eight subjects in acute cocaine withdrawal were compared to controls for connectivity in language areas while performing a task involving categorization of words according to semantic and phonological relatedness. Acute withdrawal subjects had significantly less overall connectivity during semantic relatedness, and a trend towards less connectivity during phonological relatedness. Of potential future interest is whether this might serve as an imaging marker for treatment in patients.

journal_name

Neurocase

journal_title

Neurocase

authors

Narayanan A,White CA,Saklayen SS,Abduljalil A,Schmalbrock P,Pepper TH,Lander BN,Beversdorf DQ

doi

10.1080/13554794.2011.627341

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

441-9

issue

6

eissn

1355-4794

issn

1465-3656

journal_volume

18

pub_type

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