Spontaneous confabulations in amnestic-mild cognitive impairment due to Alzheimer's disease: a new (yet old) atypical variant?

Abstract:

:Confabulation may be present in Alzheimer's disease (AD), but usually it is not a primary feature of either its typical or atypical variants. In this report, we describe the case of an AD patient who showed an unusual and enduring neuropsychiatric phenotype characterized by early and prominent spontaneous confabulation. Surprisingly, such atypical AD presentation bears a striking resemblance to presbyophrenia, a subtype of dementia which was described at the beginning of the twentieth century and then sank into oblivion. In discussion, we speculate on the "return" of presbyophrenia as an unrecognized neuropsychiatric variant of AD and its possible neuroanatomical substrates.

journal_name

Neurocase

journal_title

Neurocase

authors

Abbate C,Trimarchi PD,Rotondo E,Inglese S,Nicolini P,Rossi PD,Arosio B,Mari D

doi

10.1080/13554794.2016.1239743

subject

Has Abstract

pub_date

2016-10-01 00:00:00

pages

451-460

issue

5

eissn

1355-4794

issn

1465-3656

journal_volume

22

pub_type

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