Abstract:
:After a unilateral brain lesion, patients may show cross-modal, visual-tactile extinction. Such patients may fail to report tactile stimuli on the contralesional hand when presented together with competing visual stimuli near the ipsilesional hand. In this work we tested the hypothesis that this cross-modal extinction may be reduced when a patient has used a tool with the contralesional hand to reach for objects in the ipsilesional visual field. Consistent with previous work, we hypothesize that active use of a tool may extend cross-modal interactions between visual stimuli at the tip of the tool and tactile stimuli on the hand wielding the tool. In the new situation of a tool connecting the contralesional hand with ipsilesional visual space, competition between stimuli on these opposite sides may be reduced, so that extinction decreases. We studied patient BV, who showed reliable cross-modal, visual-tactile extinction after right-hemisphere stroke. In two separate sessions we showed that prolonged tool use (10-20 min) with the contralesional hand in ipsilesional space reduced cross-modal extinction for up to 60-90 min post-training. We propose that an actively used tool may be effective in linking cross-modal stimuli presented along its extension. This can then overcome competition between stimuli presented on opposite sides of the body midline, thus modulating extinction.
journal_name
Neurocasejournal_title
Neurocaseauthors
Maravita A,Clarke K,Husain M,Driver Jdoi
10.1076/neur.8.5.411.16177subject
Has Abstractpub_date
2002-01-01 00:00:00pages
411-6issue
6eissn
1355-4794issn
1465-3656journal_volume
8pub_type
杂志文章相关文献
NEUROCASE文献大全abstract::A 62-year-old male presented with progressive isolated writing and spelling difficulties. Neurological, neuropsychological, speech, and language evaluations identified only minimal additional abnormalities. The presenting characteristics did not meet criteria for any particular variant of primary progressive aphasia; ...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2018.1454963
更新日期:2018-04-01 00:00:00
abstract::The noradrenergic system modulates performance on tasks dependent on semantic and associative network flexibility (NF) in individuals without neurodevelopmental diagnoses in experiments using a beta-adrenergic antagonist, propranolol. Some studies suggest drugs decreasing noradrenergic activity are beneficial in ASD. ...
journal_title:Neurocase
pub_type: 临床试验,杂志文章
doi:10.1080/13554790802368661
更新日期:2008-01-01 00:00:00
abstract::We investigated the nature of covertly processed visual elements in a patient with simultanagnosia, a disorder characterized by the inability to perceive multiple aspects of a visual scene all at once. Using the first letter of the color words red, green, or blue, we created a novel testing paradigm that combined Navo...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2015.1137949
更新日期:2016-06-01 00:00:00
abstract::The amygdala nuclei appear to be critically implicated in emotional memory. However, in most studies, encoding and consolidation processes cannot be analyzed separately. We thus studied the verbal emotional memory in a young woman with a ganglioglioma of the left amygdala and analyzed its impact (1) on each step of th...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2015.1037843
更新日期:2016-01-01 00:00:00
abstract::The degree of abnormality and rate of change in cognitive functions, positron emission tomography Pittsburg compound B (PET PIB), and fluorodeoxyglucose (FDG) measures were studied for 8 years in an autopsy-confirmed Alzheimer's disease (AD) patient, who died 61 years old (Mini-Mental State Examination (MMSE) score 7)...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2014.979835
更新日期:2015-01-01 00:00:00
abstract::To further understand the nature of the visual-spatial representations required for successful acquisition of written language skills, we investigated the written language abilities of two individuals with Williams syndrome (WS) a developmental genetic disorder in which the presence of severe visual-spatial developmen...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2012.667127
更新日期:2013-08-01 00:00:00
abstract::A 54-year-old art teacher, experienced a right putaminal hemorrhage, and thereafter suffered severe left hemiplegia and unilateral spatial neglect, and was transferred to the rehabilitation department of the University Hospital 1 month after the onset. Although the unilateral spatial neglect was improving, the patient...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2011.588175
更新日期:2012-06-01 00:00:00
abstract::The delay between cardiac arrest and brain MRI is usually extremely different in the few cerebral imaging studies assessing the affected brain areas. We report an unusual case of loss of psychic self-activation appeared immediately after a cardiac arrest in a middle age patient. The first brain MRI, one month after th...
journal_title:Neurocase
pub_type: 临床试验,杂志文章
doi:10.1080/13554794.2019.1608263
更新日期:2019-01-01 00:00:00
abstract::In large early cortical lesions, one of the most devastating consequences is the impaired motor dexterity of the contralateral limb. We present the case of an 8-year-old girl with a large left hemispherical porencephaly. Unlike previous reports, the girl exhibited high dexterity of the contralateral hand with preserve...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554790601126195
更新日期:2006-10-01 00:00:00
abstract::Short melodies are commonly linked to referents in jingles, ringtones, movie themes, and even auditory displays (i.e., sounds used in human-computer interactions). While melody associations can be quite effective, auditory alarms in medical devices are generally poorly learned and highly confused. Here, we draw on app...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2016.1253751
更新日期:2016-12-01 00:00:00
abstract::Regressive behavior is a known sequela after severe traumatic brain injury (TBI). However, prolonged "infantile-like" behavior has received little attention in the literature, suggesting that this is a rare phenomenon. It is typically characterized by long-lasting childish, extremely dependent, and sometimes aggressiv...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2013.826680
更新日期:2014-01-01 00:00:00
abstract::One typical feature of the neglect syndrome in patients with right hemisphere damage is that they bisect horizontal lines to the right of centre. It has been argued that to a large extent these bisection errors can be attributed to a perceptual change whereby the patient experiences the left half of a line as shorter ...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1076/neur.7.5.391.16246
更新日期:2001-01-01 00:00:00
abstract::We investigated the neural systems that support number processing in a patient (JL) who had damage to the left ventral occipito-temporal cortex (LvOT). JL had severely impaired written word recognition but he was remarkably accurate in number tasks, albeit slower than normal. This suggests LvOT activation is necessary...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2011.588179
更新日期:2012-01-01 00:00:00
abstract::After a stroke involving the left occipitotemporal cortex our patient shows a word-length effect and has problems to identify letters or numbers in strings of symbols. But he is normal in identifying isolated letters and in non-verbally categorizing even complex images such as faces or natural scenes. His cortical les...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2019.1634739
更新日期:2019-10-01 00:00:00
abstract::A current debate in the literature is whether all declarative memories and associated memory processes rely on the same neural substrate. Here, we show that H.C., a developmental amnesic person with selective bilateral hippocampal volume loss, has a mild deficit in personal episodic memory, and a more pronounced defic...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2010.532138
更新日期:2011-10-01 00:00:00
abstract::We report a case of frontotemporal dementia caused by a novel MAPT mutation (Q351R) with a remarkably long amnestic presentation mimicking familial Alzheimer's disease. Longitudinal clinical, neuropsychological and imaging data provide convergent evidence for predominantly bilateral anterior medial temporal lobe invol...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2013.826697
更新日期:2014-01-01 00:00:00
abstract::Creatine transporter deficit (CT1) is an inherited metabolic disorder that causes mental retardation, epilepsy, speech, language and behavioral deficits. Until now, no treatment has been proven to be successful for this condition. We describe 1-year follow-up study of a child, aged 9.6 years, with CT1 defect, on oral ...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554790802060821
更新日期:2008-01-01 00:00:00
abstract::A 75 year-old man had a two-year history of progressive memory loss, trouble with finances and getting lost. On examination, he scored 16/30 in MoCA test, noticeably impaired on the attentional tasks. His screening bloodtests werenormal. Brain imaging revealed hippocampal atrophy and bilaterallarge areas of leukoaraio...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2020.1769138
更新日期:2020-08-01 00:00:00
abstract::We report a patient presenting with clinical features of logopenic variant primary progressive aphasia (lvPPA) who was later diagnosed with probable dementia with Lewy bodies. LvPPA is a neurodegenerative disease that is characterized by anomia, word-finding difficulty, impaired comprehension, and phonological errors....
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2020.1795204
更新日期:2020-10-01 00:00:00
abstract::The psychoses of epilepsy are well recognized complications of seizure disorders, diagnosed easily from the history. However, in the absence of recognized seizures, the diagnosis can be challenging. We present a 27-year-old female, who suffered a treatment refractory psychosis for 6 years. She did not report, or dis...
journal_title:Neurocase
pub_type: 杂志文章,评审
doi:10.1080/13554794.2011.627338
更新日期:2012-01-01 00:00:00
abstract::Gerstmann-Sträussler-Scheinker syndrome is a rare autosomal dominant disease caused by a mutation in the prion gene, usually manifesting as progressive ataxia with late cognitive decline. A 44-year-old woman with a positive family history developed early personality and behavior changes, followed by paresthesias and a...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2011.654215
更新日期:2013-01-01 00:00:00
abstract::Central pontine and extrapontine myelinolysis (CPEM) is a rare neurological condition usually due to rapid correction of hyponatremia. CPEM is mainly characterized by motor deficits (typically quadraparesis or extrapyramidal features) but neurobehavioral symptoms were also reported in the literature. However, very few...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2011.633528
更新日期:2012-01-01 00:00:00
abstract::Vagus Nerve Stimulation (VNS) is approved by the FDA for treatment of both epilepsy and depression. Recent work has shown that VNS acutely affects pain perception in humans, actually increasing pain sensitivity momentarily while the device is firing. It is unclear how this acutely increased sensitivity might change ov...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554790600788094
更新日期:2006-08-01 00:00:00
abstract::For functional neuroimaging studies of stuttering, two challenges are (1) the elicitation of naturally stuttered versus fluent speech and (2) the separation of activation associated with abnormal motor execution from activation that reflects the cognitive substrates of stuttering. This paper reports on a proof-of-conc...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2013.791863
更新日期:2014-08-01 00:00:00
abstract::Psychiatric disorders represent common comorbidities in epileptic patients. Sometimes anxiety is part of the ictal semiology, especially during seizures arising from/involving frontal or temporal lobes. We describe a patient with focal epilepsy and recurrent hyperkinetic seizures who also presented prolonged episodes ...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2020.1741647
更新日期:2020-04-01 00:00:00
abstract::In this paper we report the results of a longitudinal study which examined memory for a single routine activity of daily living in people with dementia of the Alzheimer type. We assessed memory in a natural setting, visiting volunteers in their homes. We video-taped performance on the selected task and analysed the re...
journal_title:Neurocase
pub_type: 临床试验,杂志文章
doi:10.1093/neucas/8.1.111
更新日期:2002-01-01 00:00:00
abstract::Recent research revealed decreased access to semantic and associative networks in acute cocaine withdrawal. In autism, such behavioral outcomes are associated with decreased functional connectivity using functional magnetic resonance imaging. Therefore, we wished to determine whether connectivity is also decreased in ...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2011.627341
更新日期:2012-01-01 00:00:00
abstract::A 51-year-old right-handed man developed hypersexuality after a second right temporal lobectomy to treat epilepsy. His hypersexuality started with increased marital intercourse and masturbation but he later downloaded child pornography. Hyperphagia and distractibility, other features of the Kluver-Bucy syndrome, also ...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554790903329182
更新日期:2010-04-01 00:00:00
abstract::Physical symptoms of myoclonus dystonia due to epsilon-sarcoglycan mutations are well documented; however, the progression of neuropsychiatric and cognitive symptoms remains unclear. We present a case of a 34-year-old woman with early childhood onset of myoclonic jerks, dystonic posture and developmental delay due to ...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2015.1120312
更新日期:2016-01-01 00:00:00
abstract::The purpose of this study was to determine if differential reading and spelling mechanisms were involved in a Japanese patient with aphasia. In our case, the patient scored low on all of the administered reading tasks, suggesting that both the reading lexical and non-lexical routes were impaired. In contrast, his writ...
journal_title:Neurocase
pub_type: 杂志文章
doi:10.1080/13554794.2015.1137950
更新日期:2016-06-01 00:00:00