Molecular neuroimaging in primary progressive aphasia with predominant agraphia.

abstract：:The purpose of this study was to determine if differential reading and spelling mechanisms were involved in a Japanese patient with aphasia. In our case, the patient scored low on all of the administered reading tasks, suggesting that both the reading lexical and non-lexical routes were impaired. In contrast, his writ...

journal_title：Neurocase

authors： Hashimoto K,Uno A

更新日期：2016-06-01 00:00:00

abstract：:The semantic variant of primary progressive aphasia (PPA-S) is characterized by impairments in confrontation naming and single word comprehension. Although episodic memory may be relatively spared, there can be impairment in verbal learning tasks. We report a patient with PPA-S and impaired verbal learning who was tes...

journal_title：Neurocase

authors： Milano NJ,Williamson JB,Heilman KM

更新日期：2015-01-01 00:00:00

abstract：:Psychiatric disorders represent common comorbidities in epileptic patients. Sometimes anxiety is part of the ictal semiology, especially during seizures arising from/involving frontal or temporal lobes. We describe a patient with focal epilepsy and recurrent hyperkinetic seizures who also presented prolonged episodes ...

journal_title：Neurocase

authors： Albini M,Morano A,Fattouch J,Fanella M,Avorio F,Basili LM,Cerulli Irelli E,Manfredi M,Giallonardo AT,Di Bonaventura C

更新日期：2020-04-01 00:00:00

abstract：:A quantitative assessment of a distortion involving the left side of space, both in two-dimensional (drawing), and three-dimensional (modeling), visuo-constructional tasks is reported in a patient with a right temporoparieto-occipital lesion, and left hemianopia, without visuospatial neglect. In drawing and clay model...

journal_title：Neurocase

authors： Rode G,Revol P,Rossetti Y,Vallar G

更新日期：2008-01-01 00:00:00

abstract：:In a previous report, we presented longitudinal clinical, cognitive and anatomical data of a right-handed woman, whose clinical picture evolved from progressive nonfluent aphasia with apraxia of speech to corticobasal syndrome (CBS) in the last stage of the disease. The patient died at age 57 and pathological examinat...

journal_title：Neurocase

authors： Sánchez-Valle R,Forman MS,Miller BL,Gorno-Tempini ML

更新日期：2006-12-01 00:00:00

abstract：:We studied reading performance for words and for isolated letters in a pure alexic patient. She performed reasonably well when naming isolated letters but was slower in reading letters than a control subject when reaction times (RTs) were recorded. When the patient read isolated letters, RTs were slower for a subset o...

journal_title：Neurocase

authors： Bachoud-Lévi AC,Bartolomeo P

更新日期：2003-04-01 00:00:00

abstract：:After a unilateral brain lesion, patients may show cross-modal, visual-tactile extinction. Such patients may fail to report tactile stimuli on the contralesional hand when presented together with competing visual stimuli near the ipsilesional hand. In this work we tested the hypothesis that this cross-modal extinction...

journal_title：Neurocase

authors： Maravita A,Clarke K,Husain M,Driver J

更新日期：2002-01-01 00:00:00

abstract：:The purpose of the present study was to investigate differences in brain activation with functional magnetic resonance imaging (fMRI) during imagery of painful and non-painful 'finger movements' and 'hand positioning' in a subject with an amputated arm. The subject was a right-handed man in his mid-thirties who lost h...

journal_title：Neurocase

authors： Rosén G,Hugdahl K,Ersland L,Lundervold A,Smievoll AI,Barndon R,Sundberg H,Thomsen T,Roscher BE,Tjølsen A,Engelsen B

更新日期：2001-01-01 00:00:00

abstract：:An adult female complained of enlargement of right eyes in other people. Diffusion-weighted imaging detected an abnormal high-intensity area in the region from the splenium of the corpus callosum to the major forceps on the right side. The patient reported that right eyes appeared larger in size, which suggested proso...

journal_title：Neurocase

authors： Ogawa K,Akimoto T,Takahashi K,Hara M,Morita A,Kamei S,Nakajima H,Fujishiro M,Suzuki Y,Soma M,Shikata E,Futamura A,Kawamura M

更新日期：2020-10-01 00:00:00

abstract：:In this paper we report the results of a longitudinal study which examined memory for a single routine activity of daily living in people with dementia of the Alzheimer type. We assessed memory in a natural setting, visiting volunteers in their homes. We video-taped performance on the selected task and analysed the re...

journal_title：Neurocase

authors： Rusted J,Sheppard L

更新日期：2002-01-01 00:00:00

abstract：:We investigated the nature of covertly processed visual elements in a patient with simultanagnosia, a disorder characterized by the inability to perceive multiple aspects of a visual scene all at once. Using the first letter of the color words red, green, or blue, we created a novel testing paradigm that combined Navo...

journal_title：Neurocase

authors： Shenker JI,Roberts MH

更新日期：2016-06-01 00:00:00

abstract：:We report a case of frontotemporal dementia caused by a novel MAPT mutation (Q351R) with a remarkably long amnestic presentation mimicking familial Alzheimer's disease. Longitudinal clinical, neuropsychological and imaging data provide convergent evidence for predominantly bilateral anterior medial temporal lobe invol...

journal_title：Neurocase

authors： Liang Y,Gordon E,Rohrer J,Downey L,de Silva R,Jäger HR,Nicholas J,Modat M,Cardoso MJ,Mahoney C,Warren J,Rossor M,Fox N,Caine D

更新日期：2014-01-01 00:00:00

abstract：:A case report is presented detailing the successful use of awake intraoperative memory testing while using white matter stimulation in order to isolate the fornix tracks involved in memory function. The identification of the white matter tracks of the fornix that were involved in memory function was used to tailor the...

journal_title：Neurocase

authors： Brandling-Bennett EM,Bookheimer SY,Horsfall JL,Moftakhar P,Sedrak M,Barkulis CT,Gertsch JH,MacDougall MG,Boucharel W,Nuwer MR,Bergsneider M

更新日期：2012-02-01 00:00:00

abstract：:BVR was 77 years old when he sustained a large posterior cerebral artery territory infarct. Medical, cognitive and functional data collected on four occasions over 10 years initially revealed circumscribed neurological signs, no functional or cognitive deficits. BVR became significantly impaired only after two other s...

journal_title：Neurocase

authors： Piguet O,Bennett HP,Waite LM,Kril JJ,Creasey H,Anthony Broe G,Halliday GM

更新日期：2006-04-01 00:00:00

abstract：:Although structural brain scans help assess brain injury in stroke, they cannot identify regions that are functionally disabled due to disrupted perfusion. Perfusion and functional MRI have the potential for determining the functional consequences of stroke. Here we examine the effectiveness of functional MRI to measu...

journal_title：Neurocase

authors： Fridriksson J,Rorden C,Morgan PS,Morrow KL,Baylis GC

更新日期：2006-06-01 00:00:00

abstract：:Depression following stroke (PSD) affects up to 33% of patients and is associated with increased mortality. Antidepressant drugs have several side effects; therefore novel treatments are needed. Transcranial direct current stimulation (tDCS) has induced mood and cognitive gain in several neuropsychiatric conditions bu...

journal_title：Neurocase

authors： Bueno VF,Brunoni AR,Boggio PS,Bensenor IM,Fregni F

更新日期：2011-08-01 00:00:00

abstract：:Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective treatment for Parkinson's disease, but can lead to adverse effects including psychiatric disturbance. Little is known about the risk factors and treatment options for such effects. Here, we describe a patient who reproducibly developed stimu...

journal_title：Neurocase

authors： Schilbach L,Weiss PH,Kuhn J,Timmermann L,Klosterkötter J,Huff W

更新日期：2012-01-01 00:00:00

abstract：:The impact of epileptiform activity on the functional organization of various cortical regions is currently a widely discussed topic. Our patient, suffering from left-sided temporal lobe epilepsy with typical mesiotemporal sclerosis, had a remarkable history of a clear-cut handedness shift in early childhood. In this ...

journal_title：Neurocase

authors： Chlebus P,Brázdil M,Hlustík P,Mikl M,Pazourková M,Krupa P

更新日期：2004-08-01 00:00:00

abstract：:The frontal midline structures have been demonstrated by functional neuroimaging to be involved in the affective control of human behavior. However, due to the rareness of diseases affecting this part of the brain little is known about behavioral abnormalities following damage to these brain areas. We present a patien...

journal_title：Neurocase

authors： Schäfer R,Popp K,Jörgens S,Lindenberg R,Franz M,Seitz RJ

更新日期：2007-06-01 00:00:00

abstract：:While language characteristics of logopenic variant primary progressive aphasia (lvPPA) are well-defined, behavioral characteristics are less understood. We investigated correlations between language and behavioral scores across three variants of primary progressive aphasia (PPA) and found language performance and beh...

journal_title：Neurocase

authors： Keator LM,Wright AE,Saxena S,Kim K,Demsky C,Sebastian R,Sheppard SM,Breining B,Hillis AE,Tippett DC

更新日期：2019-01-01 00:00:00

abstract：:Frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U) is one of the most common pathological findings associated with the clinical FTLD syndromes. However, molecular characterization with genetic sequencing and protein expression techniques are recognizing many new subtypes for FTLDs. FTLDs are...

journal_title：Neurocase

authors： Farmer JG,Crain BJ,Harris BT,Turner RS

更新日期：2013-01-01 00:00:00

abstract：:Children (aged 9-12) training in an El Sistema-inspired program (OrKidstra) and a matched comparison group participated in an auditory Go/No-Go task while event-related potentials (ERPs) were recorded. Entire-sweep waveform patterns correlated with known ERP peaks associated with executive and other cognitive function...

journal_title：Neurocase

authors： Hedayati N,Schibli K,D'Angiulli A

更新日期：2016-12-01 00:00:00

abstract：:It has been suggested that formal thought disorder, the incoherent speech of schizophrenia, may involve a language disturbance among other abnormalities, or even be a form of dysphasia. Six patients with and seven without formal thought disorder were evaluated on an aphasia test battery. Spontaneous speech was also an...

journal_title：Neurocase

authors： Oh TM,McCarthy RA,McKenna PJ

更新日期：2002-01-01 00:00:00

abstract：:Creatine transporter deficit (CT1) is an inherited metabolic disorder that causes mental retardation, epilepsy, speech, language and behavioral deficits. Until now, no treatment has been proven to be successful for this condition. We describe 1-year follow-up study of a child, aged 9.6 years, with CT1 defect, on oral ...

journal_title：Neurocase

authors： Chilosi A,Leuzzi V,Battini R,Tosetti M,Ferretti G,Comparini A,Casarano M,Moretti E,Alessandri MG,Bianchi MC,Cioni G

更新日期：2008-01-01 00:00:00

abstract：:We have seen a patient with a profound, isolated, and quite selective deficit in proverb interpretation-aproverbia. The patient presented to us after an anoxic brain injury with aproverbia. Interestingly, the aproverbia appeared to be premorbid to the presenting event. Furthermore, the patient had no brain lesion that...

journal_title：Neurocase

authors： Brown C,Smith-Benjamin S,Patira R,Altschuler EL

更新日期：2016-06-01 00:00:00

abstract：:Subject GSI presents with a graphemic buffer deficit following a massive left fronto-parietal lesion. His errors involved essentially only consonants (98.2%). However, he always spelled correctly the first consonant in a string, and produced steadily increasing numbers of errors on the following consonants, while alwa...

journal_title：Neurocase

authors： Miceli G,Capasso R,Benvegnù B,Caramazza A

更新日期：2004-04-01 00:00:00

abstract：:Confabulation may be present in Alzheimer's disease (AD), but usually it is not a primary feature of either its typical or atypical variants. In this report, we describe the case of an AD patient who showed an unusual and enduring neuropsychiatric phenotype characterized by early and prominent spontaneous confabulatio...

journal_title：Neurocase

authors： Abbate C,Trimarchi PD,Rotondo E,Inglese S,Nicolini P,Rossi PD,Arosio B,Mari D

更新日期：2016-10-01 00:00:00

abstract：:Oculocutaneous albinism (OCA) is a group of autosomal recessive disorders characterized by impairment in the melanin synthesis. We report two siblings with OCA who presented with symptoms of autism spectrum disorder and attention deficit hyperactivity disorder (ADHD). Ocular side effects occured after methylphenidate ...

journal_title：Neurocase

authors： Ünsel Bolat G

更新日期：2020-12-01 00:00:00

abstract：:Primary progressive apraxia of speech (PPAOS) is a neurodegenerative disorder in which AOS is the sole presenting complaint. We report clinical and neuroimaging data spanning 10 years from disease onset-to-death in a 49 year-old male PPAOS patient, DY, who died with corticobasal degeneration. He presented with AOS wit...

journal_title：Neurocase

authors： Tetzloff KA,Duffy JR,Strand EA,Machulda MM,Boland SM,Utianski RL,Botha H,Senjem ML,Schwarz CG,Josephs KA,Whitwell JL

更新日期：2018-04-01 00:00:00

abstract：:This case study describes the neurocognitive presentation of a child with identified genetic abnormalities of trisomy 6 and monosomy 21 who was evaluated as part of a standard medical protocol for cochlear implantation following diagnosis of profound sensorineural hearing loss. This child received neurocognitive testi...

journal_title：Neurocase

authors： Katzenstein JM,Oghalai JS,Tonini R,Baker D,Haymond J,Caudle SE

更新日期：2009-01-01 00:00:00