Measuring the hemodynamic response in chronic hypoperfusion.

Abstract:

:Although structural brain scans help assess brain injury in stroke, they cannot identify regions that are functionally disabled due to disrupted perfusion. Perfusion and functional MRI have the potential for determining the functional consequences of stroke. Here we examine the effectiveness of functional MRI to measure brain function in a single patient (LB) with chronic hypoperfusion. When LB made sustained hand movements we observed a sustained decrease in the fMRI signal, while normal individuals exhibit a sustained increase in signal while conducting this task. This work has clear implications for understanding stroke using functional MRI.

journal_name

Neurocase

journal_title

Neurocase

authors

Fridriksson J,Rorden C,Morgan PS,Morrow KL,Baylis GC

doi

10.1080/13554790600598816

subject

Has Abstract

pub_date

2006-06-01 00:00:00

pages

146-50

issue

3

eissn

1355-4794

issn

1465-3656

pii

L3N633N764761745

journal_volume

12

pub_type

杂志文章
  • Is there a schizophasia? A study applying the single case approach to formal thought disorder in schizophrenia.

    abstract::It has been suggested that formal thought disorder, the incoherent speech of schizophrenia, may involve a language disturbance among other abnormalities, or even be a form of dysphasia. Six patients with and seven without formal thought disorder were evaluated on an aphasia test battery. Spontaneous speech was also an...

    journal_title:Neurocase

    pub_type: 临床试验,杂志文章

    doi:10.1093/neucas/8.3.233

    authors: Oh TM,McCarthy RA,McKenna PJ

    更新日期:2002-01-01 00:00:00

  • Hemispheric processing of vocal emblem sounds.

    abstract::Vocal emblems, such as shh and brr, are speech sounds that have linguistic and nonlinguistic features; thus, it is unclear how they are processed in the brain. Five adult dextral individuals with left-brain damage and moderate-severe Wernicke's aphasia, five adult dextral individuals with right-brain damage, and five ...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554794.2012.667122

    authors: Neumann-Werth Y,Levy ES,Obler LK

    更新日期:2013-01-01 00:00:00

  • The categorical distinction of vowel and consonant representations: evidence from dysgraphia.

    abstract::Subject GSI presents with a graphemic buffer deficit following a massive left fronto-parietal lesion. His errors involved essentially only consonants (98.2%). However, he always spelled correctly the first consonant in a string, and produced steadily increasing numbers of errors on the following consonants, while alwa...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554790409609942

    authors: Miceli G,Capasso R,Benvegnù B,Caramazza A

    更新日期:2004-04-01 00:00:00

  • Degree of abnormality is associated with rate of change in measures of beta-amyloid, glucose metabolism and cognition in an autopsy-verified Alzheimer's disease case.

    abstract::The degree of abnormality and rate of change in cognitive functions, positron emission tomography Pittsburg compound B (PET PIB), and fluorodeoxyglucose (FDG) measures were studied for 8 years in an autopsy-confirmed Alzheimer's disease (AD) patient, who died 61 years old (Mini-Mental State Examination (MMSE) score 7)...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554794.2014.979835

    authors: Almkvist O,Kadir A,Nordberg A

    更新日期:2015-01-01 00:00:00

  • Two different mechanisms for omission and substitution errors in neglect dyslexia.

    abstract::Neglect dyslexia is a reading disorder often associated with right-sided brain lesions. In reading single words, errors are mostly substitutions or omissions of letters that occupy the left-sided positions. Typically, these errors have been thought to depend on a single mechanism. Conversely, we propose that they are ...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554794.2010.498382

    authors: Martelli M,Arduino LS,Daini R

    更新日期:2011-01-01 00:00:00

  • Action-based memory in Alzheimer's disease: a longitudinal look at tea making.

    abstract::In this paper we report the results of a longitudinal study which examined memory for a single routine activity of daily living in people with dementia of the Alzheimer type. We assessed memory in a natural setting, visiting volunteers in their homes. We video-taped performance on the selected task and analysed the re...

    journal_title:Neurocase

    pub_type: 临床试验,杂志文章

    doi:10.1093/neucas/8.1.111

    authors: Rusted J,Sheppard L

    更新日期:2002-01-01 00:00:00

  • The effects of prosody on sentence comprehension: evidence from a neurotypical control group and seven cases of chronic stroke.

    abstract::Both prosody and sentence structure (e.g., canonical versus non-canonical) affect sentence comprehension. However, few previous studies have examined a possible interaction between prosody and sentence structure. In adult controls we found a significant interaction: typical sentence prosody, versus list prosody, facil...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554794.2019.1630447

    authors: LaCroix AN,Blumenstein N,Houlihan C,Rogalsky C

    更新日期:2019-01-01 00:00:00

  • Highly functional ipsilateral motor control after extensive left hemispheric damage during gestation.

    abstract::In large early cortical lesions, one of the most devastating consequences is the impaired motor dexterity of the contralateral limb. We present the case of an 8-year-old girl with a large left hemispherical porencephaly. Unlike previous reports, the girl exhibited high dexterity of the contralateral hand with preserve...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554790601126195

    authors: Weber B,Fliessbach K,Elger CE

    更新日期:2006-10-01 00:00:00

  • Pure alexia with intact perception of complex visual stimuli: a case study.

    abstract::After a stroke involving the left occipitotemporal cortex our patient shows a word-length effect and has problems to identify letters or numbers in strings of symbols. But he is normal in identifying isolated letters and in non-verbally categorizing even complex images such as faces or natural scenes. His cortical les...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554794.2019.1634739

    authors: Spang KM,Grimsen C,Brunner F,Fahle MW

    更新日期:2019-10-01 00:00:00

  • Active tool use with the contralesional hand can reduce cross-modal extinction of touch on that hand.

    abstract::After a unilateral brain lesion, patients may show cross-modal, visual-tactile extinction. Such patients may fail to report tactile stimuli on the contralesional hand when presented together with competing visual stimuli near the ipsilesional hand. In this work we tested the hypothesis that this cross-modal extinction...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1076/neur.8.5.411.16177

    authors: Maravita A,Clarke K,Husain M,Driver J

    更新日期:2002-01-01 00:00:00

  • Progression of neuropsychiatric and cognitive features due to exons 2 to 5 deletion in the epsilon-sarcoglycan gene: a case report.

    abstract::Physical symptoms of myoclonus dystonia due to epsilon-sarcoglycan mutations are well documented; however, the progression of neuropsychiatric and cognitive symptoms remains unclear. We present a case of a 34-year-old woman with early childhood onset of myoclonic jerks, dystonic posture and developmental delay due to ...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554794.2015.1120312

    authors: Multani N,Moro E,Lang A,Zurowski M,Duff Canning S,Tartaglia MC

    更新日期:2016-01-01 00:00:00

  • Monocular patching affects inattention but not perseveration in spatial neglect.

    abstract::Monocular patching might improve perceptual-attentional, not motor-intentional deficits in a patient with chronic post-stroke left spatial neglect. Performing a line-cancellation task, his omission errors were associated with a perceptual-attentional 'where' deficit, while perseverative errors were associated with 'ai...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554790902776888

    authors: Khurshid S,Longin H,Crucian GP,Barrett AM

    更新日期:2009-08-01 00:00:00

  • Severe impairment in grammar does not preclude theory of mind.

    abstract::Debates about the role of language in human thinking are increasingly prominent in the cognitive sciences. There are claims that certain forms of reasoning can only be performed through access to the resources of the language faculty. In particular, a component of social cognition involving the representation of the m...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1093/neucas/7.6.489

    authors: Varley R,Siegal M,Want SC

    更新日期:2001-01-01 00:00:00

  • Complete, bilateral hippocampal ischemia: a case series.

    abstract::Acute and complete ischemia of the hippocampi represents a rare cause of amnesia. This paper describes the features of four such cases presenting to a single tertiary care center over a 3-year period. Interestingly, in three instances, toxicology screening was positive for opioids at the time of presentation, while in...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554794.2016.1213299

    authors: Small JE,Butler PM,Zabar Y,Barash JA

    更新日期:2016-10-01 00:00:00

  • Dissociation of social cognition and executive function in frontal variant frontotemporal dementia.

    abstract::In this paper, we adopt a neurodevelopmental stance to examining frontal variant frontotemporal dementia (fv-FTD) by using experimental procedures from the literature on the growth of social behaviour in children to examine the deficits in social reasoning which may underpin behavioural disturbance in fv-FTD. We prese...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1093/neucas/7.2.123

    authors: Lough S,Gregory C,Hodges JR

    更新日期:2001-01-01 00:00:00

  • Alzheimer's disease neuropathologic changes in semantic dementia.

    abstract:UNLABELLED:Neuropathologic change underlying primary progressive aphasia (PPA) most commonly includes one of the frontotemporal lobar degenerations, such as FTLD-tau or FTLD-ubiquitin. The next most frequent etiology of PPA is Alzheimer's disease (AD). We describe 5 subjects with clinical diagnoses of semantic dementia...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554790903193174

    authors: Chow TW,Varpetian A,Moss T,Vinters HV,Marquez S,Miller C

    更新日期:2010-02-01 00:00:00

  • Temporal lobe epilepsy masquerading as psychosis--a case report and literature review.

    abstract::The psychoses of epilepsy are well recognized complications of seizure disorders, diagnosed easily from the history. However, in the absence of recognized seizures, the diagnosis can be challenging. We present a 27-year-old female, who suffered a treatment refractory psychosis for 6 years. She did not report, or dis...

    journal_title:Neurocase

    pub_type: 杂志文章,评审

    doi:10.1080/13554794.2011.627338

    authors: Needham E,Hamelijnck J

    更新日期:2012-01-01 00:00:00

  • A case of prosopometamorphopsia caused by infarction of the splenium of the corpus callosum and major forceps.

    abstract::An adult female complained of enlargement of right eyes in other people. Diffusion-weighted imaging detected an abnormal high-intensity area in the region from the splenium of the corpus callosum to the major forceps on the right side. The patient reported that right eyes appeared larger in size, which suggested proso...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554794.2020.1797819

    authors: Ogawa K,Akimoto T,Takahashi K,Hara M,Morita A,Kamei S,Nakajima H,Fujishiro M,Suzuki Y,Soma M,Shikata E,Futamura A,Kawamura M

    更新日期:2020-10-01 00:00:00

  • Lack of orientation due to a congenital brain malformation: a case study.

    abstract::Topographical disorientation is usually described in patients who have lost the ability to orient themselves as a consequence of acquired focal brain damage. Here, we describe the case of a 20-year-old woman with a congenital brain malformation who has never been able to orient herself within the environment. We addre...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554790500423602

    authors: Iaria G,Incoccia C,Piccardi L,Nico D,Sabatini U,Guariglia C

    更新日期:2005-12-01 00:00:00

  • The Influence of refractoriness upon comprehension of non-verbal auditory stimuli.

    abstract::An investigation of non-verbal auditory comprehension in two patients with global aphasia following stroke is reported. The primary aim of the investigation was to establish whether refractory access disorders can affect non-verbal input modalities. All previous reports of refractoriness, a cognitive syndrome characte...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554790802498955

    authors: Crutch SJ,Warrington EK

    更新日期:2008-01-01 00:00:00

  • Functional connectivity during language processing in acute cocaine withdrawal: a pilot study.

    abstract::Recent research revealed decreased access to semantic and associative networks in acute cocaine withdrawal. In autism, such behavioral outcomes are associated with decreased functional connectivity using functional magnetic resonance imaging. Therefore, we wished to determine whether connectivity is also decreased in ...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554794.2011.627341

    authors: Narayanan A,White CA,Saklayen SS,Abduljalil A,Schmalbrock P,Pepper TH,Lander BN,Beversdorf DQ

    更新日期:2012-01-01 00:00:00

  • A paradigm for awake intraoperative memory mapping during forniceal stimulation.

    abstract::A case report is presented detailing the successful use of awake intraoperative memory testing while using white matter stimulation in order to isolate the fornix tracks involved in memory function. The identification of the white matter tracks of the fornix that were involved in memory function was used to tailor the...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554794.2010.547509

    authors: Brandling-Bennett EM,Bookheimer SY,Horsfall JL,Moftakhar P,Sedrak M,Barkulis CT,Gertsch JH,MacDougall MG,Boucharel W,Nuwer MR,Bergsneider M

    更新日期:2012-02-01 00:00:00

  • FDG-PET measurement is more accurate than neuropsychological assessments to predict global cognitive deterioration in patients with mild cognitive impairment.

    abstract::The accurate prediction, at a pre-dementia stage of Alzheimer's disease (AD), of the subsequent clinical evolution of patients would be a major breakthrough from both therapeutic and research standpoints. Amnestic mild cognitive impairment (MCI) is presently the most common reference to address the pre-dementia stage ...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554790490896938

    authors: Chételat G,Eustache F,Viader F,De La Sayette V,Pélerin A,Mézenge F,Hannequin D,Dupuy B,Baron JC,Desgranges B

    更新日期:2005-02-01 00:00:00

  • Gerstmann-Sträussler-Scheinker syndrome with the P102L pathogenic mutation presenting as familial Creutzfeldt-Jakob disease: a case report and review of the literature.

    abstract::Gerstmann-Sträussler-Scheinker syndrome is a rare autosomal dominant disease caused by a mutation in the prion gene, usually manifesting as progressive ataxia with late cognitive decline. A 44-year-old woman with a positive family history developed early personality and behavior changes, followed by paresthesias and a...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554794.2011.654215

    authors: Rusina R,Fiala J,Holada K,Matějčková M,Nováková J,Ampapa R,Koukolík F,Matěj R

    更新日期:2013-01-01 00:00:00

  • Improved verbal learning in the semantic variant of primary progressive aphasia when using semantic cues.

    abstract::The semantic variant of primary progressive aphasia (PPA-S) is characterized by impairments in confrontation naming and single word comprehension. Although episodic memory may be relatively spared, there can be impairment in verbal learning tasks. We report a patient with PPA-S and impaired verbal learning who was tes...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554794.2014.894081

    authors: Milano NJ,Williamson JB,Heilman KM

    更新日期:2015-01-01 00:00:00

  • Analysis of abstract and concrete word processing in persons with aphasia and age-matched neurologically healthy adults using fMRI.

    abstract::The concreteness effect occurs in both normal and language-disordered populations. Research suggests that abstract and concrete concepts elicit differing neural activation patterns in healthy young adults, but this is undocumented in persons with aphasia (PWA). Three PWA and three age-matched controls were scanned usi...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554794.2013.770881

    authors: Sandberg C,Kiran S

    更新日期:2014-08-01 00:00:00

  • Cognition and functional performance in daily activities before and after pontine and extrapontine myelinolysis: a case study.

    abstract::Central pontine and extrapontine myelinolysis (CPEM) is a rare neurological condition usually due to rapid correction of hyponatremia. CPEM is mainly characterized by motor deficits (typically quadraparesis or extrapyramidal features) but neurobehavioral symptoms were also reported in the literature. However, very few...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554794.2011.633528

    authors: Arciero S,Kempf C,Bernard F,Gosselin N

    更新日期:2012-01-01 00:00:00

  • Degenerative dementia with proximal radial and lower vertical spatial neglect.

    abstract::A 75 year-old man had a two-year history of progressive memory loss, trouble with finances and getting lost. On examination, he scored 16/30 in MoCA test, noticeably impaired on the attentional tasks. His screening bloodtests werenormal. Brain imaging revealed hippocampal atrophy and bilaterallarge areas of leukoaraio...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554794.2020.1769138

    authors: Pisanuwongrak K,Julayanont P,Heilman KM

    更新日期:2020-08-01 00:00:00

  • The effect of virtual visual feedback on supernumerary phantom limb pain in a patient with high cervical cord injury: a single-case design study.

    abstract::We characterized the effect of virtual visual feedback (VVF) on supernumerary phantom limb pain (SPLP) in a patient with high cervical cord injury. The subject was a 22-year-old man diagnosed with complete spinal cord injury (level C2) approximately 5 years ago. We applied the ABA'B' single-case design and set phases ...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554794.2015.1011664

    authors: Katayama O,Iki H,Sawa S,Osumi M,Morioka S

    更新日期:2015-01-01 00:00:00

  • Sensory function in severe semilobar holoprosencephaly.

    abstract::We report a 4-year-old child with severe semi-lobar holoprosencephaly (HPE) not expected to survive after birth. Magnetic resonance imaging (MRI) revealed agenesis of the corpus callosum, absence of the third ventricle, fused thalami and basal ganglia. To investigate sensory function, visual, auditory and somatosensor...

    journal_title:Neurocase

    pub_type: 杂志文章

    doi:10.1080/13554790802631936

    authors: Liasis A,Hildebrand D,Clark C,Katz X,Gunny R,Stieltjes B,Taylor D

    更新日期:2009-01-01 00:00:00