Abstract：
:In order to study in detail the processes leading to the resorption and ankylosis of teeth after trauma, the effects of cold application on the periodontal tissues were studied in the mouse. Liquid nitrogen was applied locally to the outer surface of the lower jaw which resulted in a freezing of the incisor and its surrounding tissues. The healing processes in the damaged periodontal ligament and the accompanying phenomena of ankylosis and dental root resorption were investigated histologically at both the light and electron microscopic levels. As a result of cold application, the cells in the periodontal ligament were killed. After a few days, the ligament started to be repopulated with cells like fibroblasts and macrophages. From 3 days on, mineral crystallites were deposited along the cementum covering the lingual, mesial, and lateral surfaces of the incisor, finally resulting in a 4-6 micron thick layer. During the period of 7-12 days following cold application, this layer of mineralized material started to be phagocytosed and degraded, presumably by mononuclear cells. Finally, extensive root resorption and some ankylosis between the tooth and the alveolar bone were observed. In the resorbed areas, cells were seen which could not be distinguished from osteoclasts. In some instances, their ruffled border was in close apposition with each of the three mineralized tissues--dentin, cementum, and alveolar bone. It is hypothesized that the deposition and subsequent phagocytosis of mineralized material along the root surface may be an important factor in the initiation of dental root resorption.
journal_name
Calcif Tissue Intjournal_title
Calcified tissue internationalauthors
Wesselink PR,Beertsen W,Everts Vdoi
10.1007/BF02555735subject
Has Abstractpub_date
1986-07-01 00:00:00pages
11-21issue
1eissn
0171-967Xissn
1432-0827journal_volume
39pub_type
杂志文章abstract：:Proteoglycans are recognized to inhibit calcium pyrophosphate dihydrate (CPPD) crystal formation but the mechanisms are not known. To study the role of carboxylate (-CO2-) ligands, the possible inhibitor effects of sodium acetate, sodium D-glucuronate, disodium malate, and trisodium citrate were studied using solution...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02555838
更新日期：1988-01-01 00:00:00
abstract：:Changes in the acidity of osteoclasts were evaluated by direct measurement of the fluorescent intensity of osteoclasts exposed to acridine orange, a fluorescent weak base which becomes concentrated in acid-containing subcellular compartments. Parathyroid hormone (PTH) produced dose-dependent increases in fluorescent i...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02554924
更新日期：1985-12-01 00:00:00
abstract：:The accuracy of a radiographic absorptiometry (RA) technique called digital image processing (DIP), discriminative ability of RA for osteoporotic fracture, and the relationship between RA and dual X-ray absorptiometry (DXA) of the spine and forearm were evaluated. We measured 16 cadaver hands, 32 healthy non-black pre...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s002239900400
更新日期：1998-02-01 00:00:00
abstract：:High resolution transmission electron microscopy (Hr TEM) studies on biological and synthetic calcium phosphate have provided information on the dissolution process at the crystal level. The purpose of this study was to investigate the dissolution of ceramic hydroxyapatite (HA) after implantation using Hr TEM. Recover...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02561408
更新日期：1989-08-01 00:00:00
abstract：:A 56 year-old man with a 2-year history of transitional-cell carcinoma of the urinary bladder presented with back pain and diffuse radiological osteosclerosis. Laboratory studies revealed borderline-low ionized serum calcium, and markedly elevated serum alkaline phosphatase (ALP) activity and serum osteocalcin. Serum ...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s002239900560
更新日期：1998-12-01 00:00:00
abstract：:Residents of a long-stay geriatric ward at the University Hospital Basel were included in a study to investigate the effects of hypovitaminosis D and immobility. All 91 women (mean age 82.5 years) and 92 men (mean age 78.7 years) were enrolled in the study. Measurements included bone resorption, as measured by urinary...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s002239900638
更新日期：1999-06-01 00:00:00
abstract：:High PTH levels increase bone turnover and decrease bone mineral density (BMD). Low plasma 25-hydroxyvitamin D (25OHD) levels cause secondary hyperparathyroidism, but the relative contribution of low 25OHD and high PTH levels on risk of fracture is largely unknown. Within the cohort of women (n = 2,016) included in th...
journal_title：Calcified tissue international
pub_type： 杂志文章,多中心研究
doi：10.1007/s00223-010-9454-0
更新日期：2011-03-01 00:00:00
abstract：:A comparative polarized light (PLM), scanning (SEM), and transmission (TEM) electron microscopy study was carried out on cross- and longitudinal sections of human lamellar bone in the tibiae of four male subjects aged 9, 23, 45, and 70 years. SEM analysis was also performed on rectangular-prismatic samples in order to...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF01673402
更新日期：1993-01-01 00:00:00
abstract：:Undesired bone loss around implants is considered to occur mainly because of a stress-shielding phenomenon. Bone surrounding the total knee arthroplasty (TKA) adjusts its mineral density and structure to meet new mechanical demands. Immobilization, in combination with local operative trauma to the bone and soft tissue...
journal_title：Calcified tissue international
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00223-002-1022-9
更新日期：2002-12-01 00:00:00
abstract：:The bone mineral status of 17 girls with Turner's syndrome was evaluated by single photon absorptiometry. Bone mineral content (BMC) was 25.4% below that predicted by normalization for age, sex, height, weight, and bone width. Only 25% of this demineralization could be attributed to delayed skeletal maturation. Bones ...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02411296
更新日期：1982-01-01 00:00:00
abstract：:During mechanical unloading, endothelial cells reduce osteogenesis and increase bone resorption. Here we describe the feedback response of endothelial cells to unloaded osteoblasts. Primary endothelial cells, ex vivo mouse aortic rings and chicken egg yolk membranes were incubated with conditioned medium from mouse pr...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-018-0496-z
更新日期：2019-03-01 00:00:00
abstract：:A strategy based on high pressure liquid chromatography (HPLC) techniques for the isolation or a principal amelogenin molecule from a single human dentition is described. A partial sequence (33 residues) for this 24 kDa amelogenin is presented and related to earlier studies of human 5 kDa tyrosine-rich amelogenin poly...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02555993
更新日期：1990-08-01 00:00:00
abstract：:Hip fracture may cause and/or complicate institutionalization. We undertook this study to define its overall prevalence among the residents of four nursing homes in Central Italy as well as its latency and impact on mobility when it occurred within institutions. We also performed a case control analysis with the aim o...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s002230001212
更新日期：2001-06-01 00:00:00
abstract：:Acute spinal cord injury is associated with rapid bone loss and an increased risk of fracture. In this double-blind, randomized, placebo-controlled trial, 17 patients were followed for 1 year after administration of either 4 or 5 mg of zoledronic acid or placebo. Bone mineral density (BMD) and structural analyses of t...
journal_title：Calcified tissue international
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00223-007-9012-6
更新日期：2007-05-01 00:00:00
abstract：:Synovial fluid basic calcium phosphate (BCP) crystals are associated with severe destructive arthropathy. BCP crystals induce the secretion of matrix-degrading enzymes such as collagenase. No prophylactic or therapeutic agents are recognized to ameliorate the cartilage damage associated with BCP deposits in joints. As...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF00571332
更新日期：1993-06-01 00:00:00
abstract：:There is increasing evidence that 1,25 dihydroxyvitamin D3 acts directly to differentiate and activate cells of mononuclear phagocyte lineage (MNP). However, it seems possible that in bone marrow this hormone may modulate the differentiation of MNP via the factor elaborated by the stromal cells or the macrophages. We ...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02556592
更新日期：1986-01-01 00:00:00
abstract：:We measured serum concentrations of bone Gla-protein (osteocalcin, BGP) and carboxyterminal propeptide of type I procollagen (PICP) in 14 patients with active acromegaly. Blood was collected at 0800 for measurement of bone Gla-protein (BGP), carboxyterminal propeptide of type I procollagen (PICP), and insulin-like gro...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF00298716
更新日期：1993-03-01 00:00:00
abstract：:The severest long-term complications of orthopedic joint-prostheses are associated with loosening of the implant-bone interface, due to adverse reactions in bone and subsequent weakening of the connection between the two materials. Mechanical stresses, caused by joint loading, play a key role in the adaption of interf...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02406143
更新日期：1984-01-01 00:00:00
abstract：:The association of dietary patterns and bone health is not yet well known, and findings from the rare previous studies conducted on this issue are contradictory. We assessed the dietary patterns in relation to bone mineral density (BMD) in a sample of menopausal Iranian women. In this cross-sectional study, 160 menopa...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-012-9608-3
更新日期：2012-07-01 00:00:00
abstract：:Abnormal PTH secretion and cell growth in hyperparathyroid tissues are accompanied with reduced expression of Ca2+-sensing receptor (CaR) which plays a key role in Ca-regulated PTH release. In this study, we examined the receptor expression in parathyroid adenomas using specific anti-CaR antibody and investigated rela...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s002239900617
更新日期：1999-03-01 00:00:00
abstract：:This article reviews the effects of restrictive eating disorders on bone health. The relationship between eating disorders and amenorrhea is discussed in detail. The pathologic impact of malnutrition on bone is explored by examining the results of studies using various available imaging techniques. The multiple hormon...
journal_title：Calcified tissue international
pub_type： 杂志文章,评审
doi：10.1007/s00223-016-0164-0
更新日期：2017-05-01 00:00:00
abstract：:In general, physical exercise appears to have favorable effects on the skeleton. However, a few recent reports have described negative effects, including reduced bone density (BMD) and high bone turnover in runners. The aim of our study was to compare endurance runners to controls with respect to BMD at different site...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s002239900366
更新日期：1997-12-01 00:00:00
abstract：:The current study is based on our earlier investigation carried out in 1999, where bone mineral density (BMD) of 35 neurofibromatosis type 1 (NF1) patients was measured and osteoporosis was shown to be common in NF1. The findings have been confirmed by a number of later publications. The purpose of the current longitu...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-012-9661-y
更新日期：2013-01-01 00:00:00
abstract：:Dual-photon absorptiometry (153Gd) was used to measure bone mineral of the total body and major anatomical areas. Patients with osteoporosis (male = 11, female = 18) and with renal osteodystrophy (n = 17) were significantly below (20%) normal females (n = 72) and males (n = 13) at most sites. In the osteoporotic patie...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02405287
更新日期：1984-01-01 00:00:00
abstract：:Bruck syndrome is a rare autosomal recessive form of osteogenesis imperfecta (OI), which is mainly characterized by joint contractures and recurrent fragility fractures. Mutations in FKBP10 and PLOD2 were identified as the underlying genetic defects of Bruck syndrome. Here we investigated the phenotypes and the pathog...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-017-0360-6
更新日期：2018-03-01 00:00:00
abstract：:The Sarcopenia and Quality of Life questionnaire (SarQol®) is a self-administered multidimensional sarcopenia-specific tool designed for community-dwelling subjects aged 65 years and older. The purpose of the present study was to evaluate the psychometric properties of the Spanish version of the SarQoL®. A total of 25...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-019-00635-9
更新日期：2020-03-01 00:00:00
abstract：:The P2X7 nucleotide receptor (P2X7R) is an ATP-gated ion channel expressed in bone cells. Homozygous null P2X7R (P2X7R(-/-)) mice have reduced bone formation, so we hypothesized that P2X7R(-/-) mice have impaired fracture healing compared to P2X7R(+/+) control mice. To test the hypothesis, adult P2X7R(-/-) mice and P2...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-009-9237-7
更新日期：2009-05-01 00:00:00
abstract：:Sustained exposure to high levels of parathyroid hormone (PTH), as observed in hyperparathyroidism, is catabolic to bone. The increase in the RANKL/OPG ratio in response to continuous PTH, resulting in increased osteoclastogenesis, is well established. However, the effects of prolonged PTH exposure on key regulators o...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-016-0176-9
更新日期：2016-11-01 00:00:00
abstract：:Normal rat bone maturation has been studied using biochemical methods and hydrazine separation of matrix and mineral for X-ray diffraction. In the bone, the amount of mineral increases between 4 and 22 weeks of age, while in the matrix, the ratio of noncollagenous protein to collagen progressively decreases. In minera...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02407162
更新日期：1980-01-01 00:00:00
abstract：:We have used in situ hybridization to examine expression of collagen type I, II, and X mRNA and osteonectin mRNA in the chick epiphysis. Tissue samples from the proximal tibial growth cartilage were fixed in modified Carnoy's solution, dehydrated in ethanol, and embedded in paraffin. Longitudinal and transverse sectio...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02556062
更新日期：1989-09-01 00:00:00
