Evolutionary pattern of the hemagglutinin gene of influenza B viruses isolated in Japan: cocirculating lineages in the same epidemic season.

abstract：:Measles virus (MV) isolated in B95a cells, a marmoset B-cell line, retains full pathogenicity for cynomolgus monkeys, while its derivative obtained by adaptation to the growth in Vero cells, a monkey kidney cell line, loses the pathogenic potential (F. Kobune, H. Sakata, and A. Sugiura, J. Virol. 64:700-705, 1990). He...

journal_title：Journal of virology

authors： Takeda M,Kato A,Kobune F,Sakata H,Li Y,Shioda T,Sakai Y,Asakawa M,Nagai Y

更新日期：1998-11-01 00:00:00

abstract：:Heterologous viral infections have been shown to impact the preexisting memory CD8(+)-T-cell repertoire. Bacterial superantigens are products of common human pathogenic bacteria, including staphylococci and streptococci, that are potent T-cell-stimulatory molecules. In this report, we show that exposure to staphylococ...

journal_title：Journal of virology

authors： Huang CC,Shah S,Nguyen P,Altman JD,Blackman MA

更新日期：2002-07-01 00:00:00

abstract：:Recruitment and extravasation of T cells through the blood-brain barrier are favored by adhesion molecule-mediated interactions of circulating T cells with endothelial cells. Since a common pathological finding in human T-cell leukemia virus type 1 (HTLV-1)-associated diseases is the infiltration of HTLV-1-infected T ...

journal_title：Journal of virology

authors： Valentin H,Lemasson I,Hamaia S,Cassé H,König S,Devaux C,Gazzolo L

更新日期：1997-11-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) efficiently enters cells of Old World monkeys but encounters a block before reverse transcription. This restriction is mediated by a dominant repressive factor. Recently, a member of the tripartite motif (TRIM) family proteins, TRIM5alpha, was identified as a blocking factor...

journal_title：Journal of virology

authors： Nakayama EE,Miyoshi H,Nagai Y,Shioda T

更新日期：2005-07-01 00:00:00

abstract：:Transgenic (Tg) mice expressing full-length bovine prion protein (BoPrP) serially propagate bovine spongiform encephalopathy (BSE) prions without posing a transmission barrier. These mice also posed no transmission barrier for Suffolk sheep scrapie prions, suggesting that cattle may be highly susceptible to some sheep...

journal_title：Journal of virology

authors： Scott MR,Peretz D,Nguyen HO,Dearmond SJ,Prusiner SB

更新日期：2005-05-01 00:00:00

abstract：:The amount and distribution of viral DNA were established in a horse acutely infected with the Wyoming strain of equine infectious anemia virus (EIAV). The highest concentration of viral DNA were found in the liver, lymph nodes, bone marrow, and spleen. The kidney, choroid plexus, and peripheral blood leukocytes also ...

journal_title：Journal of virology

authors： Rice NR,Lequarre AS,Casey JW,Lahn S,Stephens RM,Edwards J

更新日期：1989-12-01 00:00:00

abstract：:Alphaherpesviruses are parasites of the peripheral nervous system in their natural hosts. After the initial infection of peripheral tissues such as mucosal cells, these neurotropic viruses will invade the peripheral nervous system that innervates the site of infection via long-distance axonal transport of the viral ge...

journal_title：Journal of virology

authors： Ch'ng TH,Enquist LW

更新日期：2005-09-01 00:00:00

abstract：:In cytomegalovirus-infected cells, the rate of protein synthesis was detected as two peaks. One occurred during the early phase of infection, 0 to 36 h postinfection, and the other occurred during the late phase, after the initiation of viral DNA synthesis. Double-isotopic-label difference analysis demonstrated that h...

journal_title：Journal of virology

authors： Stinski MF

更新日期：1977-09-01 00:00:00

abstract：:AP-1- and ATF-binding sites are cis-acting transcriptional elements within the U3 domain of the feline immunodeficiency virus (FIV) long terminal repeat (LTR) that serve as targets for cellular activation pathways and may regulate virus replication. We report that FIV LTR mutant proviruses encoding U3 deletions of the...

journal_title：Journal of virology

authors： Bigornia L,Lockridge KM,Sparger EE

更新日期：2001-01-01 00:00:00

abstract：:A well-characterized mechanism by which anti-HLA class I monoclonal antibodies (MAb) inhibit human immunodeficiency virus type 1 (HIV-1) propagation in in vitro cell cultures is the neutralization of the virus through interactions with HLA molecules associated with the virion envelope. Yet, the possibility that anothe...

journal_title：Journal of virology

authors： Briant L,Benkirane M,Girard M,Hirn M,Iosef C,Devaux C

更新日期：1996-08-01 00:00:00

abstract：:Recombinant poxvirus vectors are undergoing intensive evaluation as vaccine candidates for a variety of infectious pathogens. Avipoxviruses, such as canarypox virus, are replication deficient in mammalian cells by virtue of a poorly understood species-specific restriction. Highly attenuated vaccinia virus strains such...

journal_title：Journal of virology

authors： Zhang X,Cassis-Ghavami F,Eller M,Currier J,Slike BM,Chen X,Tartaglia J,Marovich M,Spearman P

更新日期：2007-07-01 00:00:00

abstract：:RNA plant viruses use various translational regulatory mechanisms to control their gene expression. Translational enhancement of viral mRNAs that leads to higher levels of protein synthesis from specific genes may be essential for the virus to successfully compete for cellular translational machinery. The control elem...

journal_title：Journal of virology

authors： Koh DC,Liu DX,Wong SM

更新日期：2002-02-01 00:00:00

abstract：:We constructed vaccine vectors based on live recombinant vesicular stomatitis virus (VSV) and a Semliki Forest virus (SFV) replicon (SFVG) that propagates through expression of the VSV glycoprotein (G). These vectors expressing simian immunodeficiency virus (SIV) Gag and Env proteins were used to vaccinate rhesus maca...

journal_title：Journal of virology

authors： Schell JB,Rose NF,Bahl K,Diller K,Buonocore L,Hunter M,Marx PA,Gambhira R,Tang H,Montefiori DC,Johnson WE,Rose JK

更新日期：2011-06-01 00:00:00

abstract：:Transcriptionally active replication complexes bound to smooth membrane vesicles were isolated from poliovirus-infected cells. In electron microscopic, negatively stained preparations, the replication complex appeared as an irregularly shaped, oblong structure attached to several virus-induced vesicles of a rosettelik...

journal_title：Journal of virology

authors： Bienz K,Egger D,Troxler M,Pasamontes L

更新日期：1990-03-01 00:00:00

abstract：:TNPO3 is a nuclear importer required for HIV-1 infection. Here, we show that depletion of TNPO3 leads to an HIV-1 block after nuclear import but prior to integration. To investigate the mechanistic requirement of TNPO3 in HIV-1 infection, we tested the binding of TNPO3 to the HIV-1 core and found that TNPO3 binds to t...

journal_title：Journal of virology

authors： Valle-Casuso JC,Di Nunzio F,Yang Y,Reszka N,Lienlaf M,Arhel N,Perez P,Brass AL,Diaz-Griffero F

更新日期：2012-05-01 00:00:00

abstract：:Deer mice are the principal reservoir hosts of Sin Nombre virus, the etiologic agent of most hantavirus cardiopulmonary syndrome cases in North America. Infection of deer mice results in persistence without conspicuous pathology, and most, if not all, infected mice remain infected for life, with periods of viral shedd...

journal_title：Journal of virology

authors： Schountz T,Acuña-Retamar M,Feinstein S,Prescott J,Torres-Perez F,Podell B,Peters S,Ye C,Black WC 4th,Hjelle B

更新日期：2012-09-01 00:00:00

abstract：:MicroRNAs (miRNAs) are key regulators of gene expression in higher eukaryotes. Recently, miRNAs have been identified from viruses with double-stranded DNA genomes. To attempt to identify miRNAs encoded by herpes simplex virus 1 (HSV-1), we applied a computational method to screen the complete genome of HSV-1 for seque...

journal_title：Journal of virology

authors： Cui C,Griffiths A,Li G,Silva LM,Kramer MF,Gaasterland T,Wang XJ,Coen DM

更新日期：2006-06-01 00:00:00

abstract：:A panel of 16 monoclonal antibodies recognizing M protein (M1) of influenza virus was generated. Competition analyses resulted in localization of 14 monoclonal antibodies to three antigenic sites. Three monoclonal antibodies localized to site 1B recognized a peptide synthesized to M1 (residues 220 to 236) with enzyme-...

journal_title：Journal of virology

authors： Bucher D,Popple S,Baer M,Mikhail A,Gong YF,Whitaker C,Paoletti E,Judd A

更新日期：1989-09-01 00:00:00

abstract：:Tetherin/BST-2 is a host-encoded protein that restricts a wide diversity of viruses at the stage of virion release. However, viruses have evolved antagonists of Tetherin, including the Vpu and Nef proteins of primate lentiviruses. Like other host genes subject to viral antagonism, primate Tetherin genes have evolved u...

journal_title：Journal of virology

authors： Lim ES,Malik HS,Emerman M

更新日期：2010-07-01 00:00:00

abstract：:The highly syncytium-inducing M strain and the weakly syncytium-inducing SC strain of bovine parainfluenza 3 virus differ by a single amino acid substitution in each of the hemagglutinin-neuraminidase (HN) and membrane (M) proteins, while their fusion (F) proteins are identical (T. Shioda, S. Wakao, S. Suzu, and H. Sh...

journal_title：Journal of virology

authors： Sakai Y,Shibuta H

更新日期：1989-09-01 00:00:00

abstract：:Measles virus (MV) can infect the central nervous system and, in rare cases, causes subacute sclerosing panencephalitis, characterized by a progressive degeneration of neurons. The route of MV transmission in neurons was investigated in cultured rat hippocampal slices by using MV expressing green fluorescent protein. ...

journal_title：Journal of virology

authors： Ehrengruber MU,Ehler E,Billeter MA,Naim HY

更新日期：2002-06-01 00:00:00

abstract：:The virion proteins encoded by the avian retroviral pol gene (reverse transcriptase and endonuclease) are formed by the proteolytic processing of a gag-pol fusion protein precursor. Recent studies have predicted that the avian sarcoma-leukosis virus pol precursor protein undergoes a previously undetected processing ev...

journal_title：Journal of virology

authors： Katz RA,Skalka AM

更新日期：1988-02-01 00:00:00

abstract：:An unusual set of 3' coterminal, spliced mRNAs transcribed through the BamHI A fragment have been previously identified in nasopharyngeal carcinoma (NPC) tissues. These RNAs have also been detected at low levels in Burkitt's lymphoma (BL) cell lines and Epstein-Barr virus (EBV)-transformed lymphocytes. Sequence analys...

journal_title：Journal of virology

authors： Fries KL,Sculley TB,Webster-Cyriaque J,Rajadurai P,Sadler RH,Raab-Traub N

更新日期：1997-04-01 00:00:00

abstract：:Previous studies with the herpes simplex virus type 1 X type 2 intertypic recombinant RS6 suggested that the genomic region from 0.11 to 0.14 map units is involved in neurovirulence (R. T. Javier, R. L. Thompson, and J. G. Stevens, J. Virol. 61:1978-1984, 1987). To study this further, we isolated an RS6-derived herpes...

journal_title：Journal of virology

authors： Javier RT,Izumi KM,Stevens JG

更新日期：1988-04-01 00:00:00

abstract：:The combination of an amino acid deletion at codon 67 (delta 67) and Thr-to-Gly change at codon 69 (T69G) in the reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1) is associated with high-level resistance to multiple RT inhibitors. To determine the relative contributions of the delta 67 and T69G...

journal_title：Journal of virology

authors： Imamichi T,Berg SC,Imamichi H,Lopez JC,Metcalf JA,Falloon J,Lane HC

更新日期：2000-12-01 00:00:00

abstract：:Northern (RNA) blot analysis was used to determine the spatial and temporal distribution of bovine herpesvirus 1 (BHV-1) transcripts. Total RNA was isolated from Madin-Darby bovine kidney cells which had been infected with BHV-1.2b strain K22 or BHV-1.1 strain Jura in the presence or absence of metabolic inhibitors. C...

journal_title：Journal of virology

authors： Wirth UV,Gunkel K,Engels M,Schwyzer M

更新日期：1989-11-01 00:00:00

abstract：:In response to viral infection, reactive oxygen species (ROS) mediate innate immune signaling or generate danger signals to activate immune cells. The mechanisms of virally induced ROS are poorly defined, however. We demonstrate that ROS are produced within minutes of adenovirus type 5 (Ad5) infection of macrophages a...

journal_title：Journal of virology

authors： McGuire KA,Barlan AU,Griffin TM,Wiethoff CM

更新日期：2011-10-01 00:00:00

abstract：:The rescue of influenza viruses by reverse genetics has been described only for the influenza A and B viruses. Based on a similar approach, we developed a reverse-genetics system that allows the production of influenza C viruses entirely from cloned cDNA. The complete sequences of the 3' and 5' noncoding regions of ty...

journal_title：Journal of virology

authors： Crescenzo-Chaigne B,van der Werf S

更新日期：2007-10-01 00:00:00

abstract：:The gene encoding the glycoprotein Marek's disease herpesvirus A antigen (MDHV-A) precursor polypeptide pr47 was delineated by using Northern blot (RNA blot) analysis and hybrid selection of its mRNA with cloned MDHV DNA, cell-free translation of the mRNA, and immunoprecipitation of the polypeptide. The resulting piec...

journal_title：Journal of virology

authors： Isfort RJ,Kung HJ,Velicer LF

更新日期：1987-08-01 00:00:00

abstract：:Molluscum contagiosum virus (MCV), the only member of the Molluscipoxvirus genus, causes benign papules in healthy people but disfiguring lesions in immunocompromised patients. The sequence of MCV has been completed, revealing that MCV encodes a probable type I topoisomerase enzyme. All poxviruses sequenced to date al...

journal_title：Journal of virology

authors： Hwang Y,Wang B,Bushman FD

更新日期：1998-04-01 00:00:00