Identification of the gene encoding Marek's disease herpesvirus A antigen.

abstract：:Human cytomegalovirus (CMV) is the leading cause of prenatal viral infection. Affected infants may suffer intrauterine growth retardation and serious neurologic impairment. Analysis of spontaneously aborted conceptuses shows that CMV infects the placenta before the embryo or fetus. In the human hemochorial placenta, m...

journal_title：Journal of virology

authors： Fisher S,Genbacev O,Maidji E,Pereira L

更新日期：2000-08-01 00:00:00

abstract：:Mononuclear phagocytes (MP) and T lymphocytes play a pivotal role in the host immune response to human immunodeficiency virus type 1 (HIV-1) infection. Regulation of such immune responses can be mediated, in part, through the interaction of the T-lymphocyte-expressed molecule CD40 ligand (CD40L) with its receptor on M...

journal_title：Journal of virology

authors： Cotter RL,Zheng J,Che M,Niemann D,Liu Y,He J,Thomas E,Gendelman HE

更新日期：2001-05-01 00:00:00

abstract：UNLABELLED:Hepatitis C virus (HCV) is a major cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma in humans. We showed previously that HCV induces autophagy for viral persistence by preventing the innate immune response. Knockdown of autophagy reduces extracellular HCV release, although the precis...

journal_title：Journal of virology

authors： Shrivastava S,Devhare P,Sujijantarat N,Steele R,Kwon YC,Ray R,Ray RB

更新日期：2015-11-18 00:00:00

abstract：:Infectious cDNA clones of mild (CHV1-Euro7) and severe (CHV1-EP713) hypovirus strains responsible for virulence attenuation (hypovirulence) of the chestnut blight fungus Cryphonectria parasitica were used to construct viable chimeric viruses. Differences in virus-mediated alterations of fungal colony morphology, growt...

journal_title：Journal of virology

authors： Chen B,Geletka LM,Nuss DL

更新日期：2000-08-01 00:00:00

abstract：:It has been shown previously in the severe acute respiratory syndrome coronavirus (SARS-CoV) that two point mutations, N15A and V25F, in the transmembrane domain (TMD) of the envelope (E) protein abolished channel activity and led to in vivo attenuation. Pathogenicity was recovered in mutants that also regained E prot...

journal_title：Journal of virology

authors： To J,Surya W,Fung TS,Li Y,Verdià-Bàguena C,Queralt-Martin M,Aguilella VM,Liu DX,Torres J

更新日期：2017-02-14 00:00:00

abstract：:Sequencing and reversion analysis of murine hepatitis virus (MHV) temperature-sensitive (ts) viruses has identified putative ts mutations in the replicase nonstructural proteins (nsp's) of these coronaviruses. In this study, reverse transcriptase PCR sequencing of the RNA genome of an isolate of the MHV ts virus Alb t...

journal_title：Journal of virology

authors： Sparks JS,Donaldson EF,Lu X,Baric RS,Denison MR

更新日期：2008-06-01 00:00:00

abstract：:By means of both electron microscopy and plaque assay techniques, 10(-3)m Zn(2+) has been shown to reduce the adsorption rate of male-specific filamentous deoxyribonucleic acid bacteriophages to the tips of F pili. In contrast, 10(-3)m Zn(2+) did not affect the adsorption of male-specific ribonucleic acid phages to th...

journal_title：Journal of virology

authors： Ou JT,Anderson TF

更新日期：1972-10-01 00:00:00

abstract：:The v-rel oncogene encoded by reticuloendotheliosis virus strain T is the acutely transforming member of the Rel/NF-kappaB family of transcription factors. In v-Rel-transformed cells, v-Rel exists as homodimers or heterodimers with the endogenous Rel/NF-kappaB proteins c-Rel, NF-kappaB1, NF-kappaB2, and RelA. To exami...

journal_title：Journal of virology

authors： Liss AS,Bose HR Jr

更新日期：2002-05-01 00:00:00

abstract：:We analyzed the susceptibility of 10 AKXD recombinant inbred (RI) mouse strains to lymphomas. These strains were derived from crosses of AKR/J, a highly lymphomatous strain, and DBA/2J, a weakly lymphomatous strain. Of the 10 strains analyzed, nine showed a high incidence of lymphoma development. As with the other 13 ...

journal_title：Journal of virology

authors： Gilbert DJ,Neumann PE,Taylor BA,Jenkins NA,Copeland NG

更新日期：1993-04-01 00:00:00

abstract：:Cell surface receptors exploited by human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) for infection are major determinants of tropism. HIV-1 usually requires two receptors to infect cells. Gp120 on HIV-1 virions binds CD4 on the cell surface, triggering conformational rearrangements that creat...

journal_title：Journal of virology

authors： Reeves JD,Hibbitts S,Simmons G,McKnight A,Azevedo-Pereira JM,Moniz-Pereira J,Clapham PR

更新日期：1999-09-01 00:00:00

abstract：:Since the number of human cases of infection with avian H5N1 influenza viruses is ever increasing, a pandemic outbreak caused by these viruses is feared. Therefore, in addition to virus-specific antibodies, there is considerable interest in immune correlates of protection against these viruses, which could be a target...

journal_title：Journal of virology

authors： Kreijtz JH,de Mutsert G,van Baalen CA,Fouchier RA,Osterhaus AD,Rimmelzwaan GF

更新日期：2008-06-01 00:00:00

abstract：:Defensins are innate immune effector peptides expressed at mucosal surfaces throughout the human body and are potently antiviral in vitro The role of defensins in viral pathogenesis in vivo is poorly understood; however, recent studies have revealed that defensin-virus interactions in vivo are complicated and distinct...

journal_title：Journal of virology

authors： Wilson SS,Wiens ME,Holly MK,Smith JG

更新日期：2016-05-12 00:00:00

abstract：:The deoxyribonucleic acid (DNA) of Escherichia coli B is converted by colicin E2 to products soluble in cold trichloroacetic acid; we show that this DNA degradation (hereafter termed solubilization) is subject to inhibition by infection with bacteriophage T4. At least two modes of inhibition may be differentiated on t...

journal_title：Journal of virology

authors： Swift RL,Wiberg JS

更新日期：1971-09-01 00:00:00

abstract：:Glycoproteins homologous to glycoprotein B (gB) of herpes simplex virus constitute the most highly conserved group of herpesvirus glycoproteins. This strong conservation of amino acid sequences might be indicative of a common functional role. Indeed, gB homologs have been implicated in the processes of viral entry and...

journal_title：Journal of virology

authors： Kopp A,Mettenleiter TC

更新日期：1992-05-01 00:00:00

abstract：:Natural killer T (NKT) cells are unique T lymphocytes that recognize CD1d-bound lipid antigens and play an important role in both innate and acquired immune responses against infectious diseases and tumors. We have already shown that a vesicular stomatitis virus (VSV) infection results in the rapid inhibition of murin...

journal_title：Journal of virology

authors： Renukaradhya GJ,Khan MA,Shaji D,Brutkiewicz RR

更新日期：2008-12-01 00:00:00

abstract：:The phosphoprotein P of Borna disease virus (BDV) is an essential cofactor of the viral RNA-dependent RNA polymerase. It is preferentially phosphorylated at serine residues 26 and 28 by protein kinase C epsilon (PKCepsilon) and, to a lesser extent, at serine residues 70 and 86 by casein kinase II (CKII). To determine ...

journal_title：Journal of virology

authors： Schmid S,Mayer D,Schneider U,Schwemmle M

更新日期：2007-06-01 00:00:00

abstract：:A recombinant Epstein-Barr virus (EBV) was constructed, with a positive-selection marker inserted at the site of a deletion of a DNA segment which encodes the first five transmembrane domains of LMP2A and LMP2B. Despite the mutation, the mutant recombinant EBV was able to initiate and maintain primary B-lymphocyte gro...

journal_title：Journal of virology

authors： Longnecker R,Miller CL,Tomkinson B,Miao XQ,Kieff E

更新日期：1993-08-01 00:00:00

abstract：:Carcinogenic progression of a human papillomavirus (HPV)-infected cell is often associated with integration of the viral genome in a manner which results in the loss of expression of the viral regulatory protein E2. One function of E2 is the regulation of expression of the viral oncogenes, E6 and E7. Introduction of t...

journal_title：Journal of virology

authors： Dowhanick JJ,McBride AA,Howley PM

更新日期：1995-12-01 00:00:00

abstract：:Previous analysis of hepatitis B virus (HBV) indicated base pairing between two cis-acting sequences, the 5' half of the upper stem of epsilon and phi, contributes to the synthesis of minus-strand DNA. Our goal was to identify other cis-acting sequences on the pregenomic RNA (pgRNA) involved in the synthesis of minus-...

journal_title：Journal of virology

authors： Abraham TM,Loeb DD

更新日期：2007-11-01 00:00:00

abstract：:The induction of a unique macrophage procoagulant molecule by murine hepatitis virus strain 3 correlates with the severity of viral hepatitis. The role of tyrosine phosphorylation in the signalling pathway leading to procoagulant expression was studied. Murine hepatitis virus strain 3 initiated a rapid increase in pho...

journal_title：Journal of virology

authors： Dackiw AP,Zakrzewski K,Nathens AB,Cheung PY,Fingerote R,Levy GA,Rotstein OD

更新日期：1995-09-01 00:00:00

abstract：:Polyoma virus complementary RNA, synthesized in vitro by using highly purified Escherichia coli RNA polymerase and nondefective form I polyoma DNA, was translated in a wheat germ cell-free system. Polypeptides were synthesized that comigrated on sodium dodecyl sulfate-polyacrylamide gels with the polyoma capsid protei...

journal_title：Journal of virology

authors： Mangel WF,Hewick RM,Bayley ST,Wheeler T,Harvey R,Waterfield MD,Smith AE

更新日期：1978-02-01 00:00:00

abstract：:Far-upstream element-binding protein 2 (FBP2) is an internal ribosomal entry site (IRES) trans-acting factor (ITAF) that negatively regulates enterovirus 71 (EV71) translation. This study shows that EV71 infection cleaved FBP2. Live EV71 and the EV71 replicon (but not UV-inactivated virus particles) induced FBP2 cleav...

journal_title：Journal of virology

authors： Chen LL,Kung YA,Weng KF,Lin JY,Horng JT,Shih SR

更新日期：2013-04-01 00:00:00

abstract：:The human immunodeficiency virus (HIV) Tat protein has a critical role in viral transcription, but this study focuses on its additional role as an extracellular effector of lymphocyte cell death. It is well known that Tat induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL) in peripheral blood mononu...

journal_title：Journal of virology

authors： Yang Y,Tikhonov I,Ruckwardt TJ,Djavani M,Zapata JC,Pauza CD,Salvato MS

更新日期：2003-06-01 00:00:00

abstract：:In an effort to develop a useful AIDS vaccine or vaccine component, we have generated a combinatorial library of chimeric viruses in which the sequence IGPGRAFYTTKN from the V3 loop of the MN strain of human immunodeficiency virus type 1 (HIV-1) is displayed in many conformations on the surface of human rhinovirus 14 ...

journal_title：Journal of virology

authors： Smith AD,Geisler SC,Chen AA,Resnick DA,Roy BM,Lewi PJ,Arnold E,Arnold GF

更新日期：1998-01-01 00:00:00

abstract：:Monomers of the genomic strand of hepatitis delta virus RNA were transcribed in vitro and then delivered to NIH 3T3 fibroblasts by using a liposome fusion technique. After 7 days, genome replication was detected, but only in fibroblasts that stably expressed the delta antigen. Sequence analysis of the replicated produ...

journal_title：Journal of virology

authors： Glenn JS,Taylor JM,White JM

更新日期：1990-06-01 00:00:00

abstract：:In resting CD4(+) T lymphocytes harboring human immunodeficiency virus type 1 (HIV-1), replication-competent virus persists in patients responding to highly active antiretroviral therapy (HAART). This small latent reservoir represents between 10(3) and 10(7) cells per patient. However, the efficiency of HIV-1 DNA-posi...

journal_title：Journal of virology

authors： Fondere JM,Petitjean G,Huguet MF,Salhi SL,Baillat V,Macura-Biegun A,Becquart P,Reynes J,Vendrell JP

更新日期：2004-10-01 00:00:00

abstract：:L2 cells infected with vesicular stomatitis virus under single-cycle conditions have been studied by scanning electron microscopy after preparation by the critical point drying technique. Three dimensional images of intact cells show bullet-shaped vesicular stomatitis virus virions budding singly and in radiating clus...

journal_title：Journal of virology

authors： Holmes KV

更新日期：1975-02-01 00:00:00

abstract：:Accurate and sensitive quantitation of infectious human immunodeficiency virus (HIV) has been difficult to achieve. In this report, a quantitative focal immunoassay (FIA) for HIV was developed using human HeLa cells rendered susceptible to HIV infection by introduction of the CD4 gene via a retrovirus vector. Infected...

journal_title：Journal of virology

authors： Chesebro B,Wehrly K

更新日期：1988-10-01 00:00:00

abstract：:Despite successful antiretroviral therapy (ART), low-level viremia (LLV) may be intermittently detected in most HIV-infected patients. Longitudinal blood plasma and resting CD4(+) T cells were obtained from two patients on suppressive ART to investigate the source of LLV. Single-genome sequencing of HIV-1 env from LLV...

journal_title：Journal of virology

authors： Anderson JA,Archin NM,Ince W,Parker D,Wiegand A,Coffin JM,Kuruc J,Eron J,Swanstrom R,Margolis DM

更新日期：2011-05-01 00:00:00

abstract：:Chicken embryo fibroblasts and NIH 3T3 mouse cells were transformable by DNAs of chicken cells infected with avian myelocytomatosis virus strain MC29 or with avian erythroblastosis virus. Transfection of chicken cells appeared to require replication of MC29 or avian erythroblastosis virus in the presence of a nontrans...

journal_title：Journal of virology

authors： Copeland NG,Cooper GM

更新日期：1980-03-01 00:00:00