Vesicular stomatitis virus matrix protein impairs CD1d-mediated antigen presentation through activation of the p38 MAPK pathway.

abstract：:A restriction map was constructed for the 17.5-kilobase SalI C fragment of SP82 DNA. Unfractionated SP82 DNA, the SalI C fragment, and restriction fragments derived from SalI-C were used as templates for in vitro synthesis by the Bacillus subtilis RNA polymerase, and the resulting transcripts were analyzed by gel elec...

journal_title：Journal of virology

authors： Panganiban AT,Whiteley HR

更新日期：1981-01-01 00:00:00

abstract：:Several arenaviruses, chiefly Lassa virus (LASV) and Junin virus in West Africa and Argentina, respectively, cause hemorrhagic fever (HF) disease in humans that is associated with high morbidity and significant mortality. The investigation of antiviral strategies to combat HF arenaviruses is hampered by the requiremen...

journal_title：Journal of virology

authors： Rodrigo WW,de la Torre JC,Martínez-Sobrido L

更新日期：2011-02-01 00:00:00

abstract：:Anti-human immunodeficiency virus type 1 (HIV-1) antibodies whose binding to gp120 is enhanced by CD4 binding (CD4i antibodies) are generally considered nonneutralizing for primary HIV-1 isolates. However, a novel CD4i-specific Fab fragment, X5, has recently been found to neutralize a wide range of primary isolates. T...

journal_title：Journal of virology

authors： Labrijn AF,Poignard P,Raja A,Zwick MB,Delgado K,Franti M,Binley J,Vivona V,Grundner C,Huang CC,Venturi M,Petropoulos CJ,Wrin T,Dimitrov DS,Robinson J,Kwong PD,Wyatt RT,Sodroski J,Burton DR

更新日期：2003-10-01 00:00:00

abstract：UNLABELLED:The increasing prevalence of ranavirus (RV; Iridoviridae) infections of wild and commercially maintained aquatic species is raising considerable concerns. While Xenopus laevis is the leading model for studies of immunity to RV, amphibian antiviral interferon (IFN) responses remain largely uncharacterized. Ac...

journal_title：Journal of virology

authors： Grayfer L,De Jesús Andino F,Robert J

更新日期：2014-05-01 00:00:00

abstract：:Combined Southern blot hybridization analyses of DNA digests of several clinical strains of Streptococcus pneumoniae have revealed the presence of a gene (hblR), or part of it, similar to the hbl7 gene coding for the cell wall lytic enzyme of the temperate HB-746 phage. The results confirmed that the genome of HB-746,...

journal_title：Journal of virology

authors： Romero A,Lopez R,Garcia P

更新日期：1992-05-01 00:00:00

abstract：:The Rev protein of human immunodeficiency virus type 1 (HIV-1) is essential for the expression of the structural genes of HIV-1. To determine whether a functional threshold level of Rev is required to allow efficient HIV-1 replication, CD4-positive HeLa cells, constitutively expressing a Rev-deficient provirus, were t...

journal_title：Journal of virology

authors： Pomerantz RJ,Seshamma T,Trono D

更新日期：1992-03-01 00:00:00

abstract：:We report here the complete genomic sequence of the duck Tembusu virus (DTMUV) WJ-1 strain, isolated from Muscovy ducks. This is the first complete genome sequence of DTMUV reported in southern China. Compared with the other strains (TA, GH-2, YY5, and ZJ-407) that were previously found in eastern China, WJ-1 bears a ...

journal_title：Journal of virology

authors： Zhu W,Chen J,Wei C,Wang H,Huang Z,Zhang M,Tang F,Xie J,Liang H,Zhang G,Su S

更新日期：2012-12-01 00:00:00

abstract：:The isolation and some properties of a virulent bacteriophage of Salmonella typhimurium, MB78, which is morphologically, serologically, and physiologically unrelated to P22, are reported. The phage has a noncontractile long tail with partite ends. It cannot multiply in minimal medium in the presence of citrate. MB78-i...

journal_title：Journal of virology

authors： Joshi A,Siddiqi JZ,Rao GR,Chakravorty M

更新日期：1982-03-01 00:00:00

abstract：:Parvovirus capsids are small but complex molecular machines responsible for undertaking many of the steps of cell infection, genome packing, and cell-to-cell as well as host-to-host transfer. The details of parvovirus infection of cells are still not fully understood, but the processes must involve small changes in th...

journal_title：Journal of virology

authors： Callaway HM,Feng KH,Lee DW,Allison AB,Pinard M,McKenna R,Agbandje-McKenna M,Hafenstein S,Parrish CR

更新日期：2017-01-03 00:00:00

abstract：:Zika virus (ZIKV) has emerged as a cause of congenital brain anomalies and a range of placenta-related abnormalities, highlighting the need to unveil the modes of maternal-fetal transmission. The most likely route of vertical ZIKV transmission is via the placenta. The earliest events of ZIKV transmission in the matern...

journal_title：Journal of virology

authors： Weisblum Y,Oiknine-Djian E,Vorontsov OM,Haimov-Kochman R,Zakay-Rones Z,Meir K,Shveiky D,Elgavish S,Nevo Y,Roseman M,Bronstein M,Stockheim D,From I,Eisenberg I,Lewkowicz AA,Yagel S,Panet A,Wolf DG

更新日期：2017-01-31 00:00:00

abstract：:We have previously shown that styrylquinolines (SQLs) are integrase inhibitors in vitro. They compete with the long terminal repeat substrate for integrase. Here, we describe the cellular mode of action of these molecules. We show that SQLs do not interfere with virus entry. In fact, concentrations of up to 20 times t...

journal_title：Journal of virology

authors： Bonnenfant S,Thomas CM,Vita C,Subra F,Deprez E,Zouhiri F,Desmaële D,D'Angelo J,Mouscadet JF,Leh H

更新日期：2004-06-01 00:00:00

abstract：:Enveloped virus vectors are used in a wide variety of applications. We have discovered that treatment of cultured cells with phosphatidylserine (PS) liposomes can increase virus vector infection by up to 20-fold. This effect does not abrogate virus receptor requirements, is specific to PS compared to other phospholipi...

journal_title：Journal of virology

authors： Coil DA,Miller AD

更新日期：2005-09-01 00:00:00

abstract：:The phenotypic properties of ICP27 temperature-sensitive and deletion mutants and the results of transient expression assays have demonstrated that ICP27 has a modulatory effect on viral gene expression induced by ICPs 0 and 4. In order to identify the regions of the ICP27 molecule that are responsible for its enhanci...

journal_title：Journal of virology

authors： McMahan L,Schaffer PA

更新日期：1990-07-01 00:00:00

abstract：:Propagation of the agents responsible for transmissible spongiform encephalopathies (TSEs) in cultured cells has been achieved for only a few cell lines. To establish efficient and versatile models for transmission, we developed neuroblastoma cell lines overexpressing type A mouse prion protein, MoPrP(C)-A, and then t...

journal_title：Journal of virology

authors： Nishida N,Harris DA,Vilette D,Laude H,Frobert Y,Grassi J,Casanova D,Milhavet O,Lehmann S

更新日期：2000-01-01 00:00:00

abstract：:Many of the approximately 165 proteins encoded by the African swine fever virus (ASFV) genome do not have significant similarity to known proteins and have not been studied experimentally. One such protein is DP148R. We showed that the DP148R gene is transcribed at early times postinfection. Deletion of this gene did ...

journal_title：Journal of virology

authors： Reis AL,Goatley LC,Jabbar T,Sanchez-Cordon PJ,Netherton CL,Chapman DAG,Dixon LK

更新日期：2017-11-30 00:00:00

abstract：:Influenza A virus infection can arrest autophagy, as evidenced by autophagosome accumulation in infected cells. Here, we report that this autophagosome accumulation can be inhibited by amantadine, an antiviral proton channel inhibitor, in amantadine-sensitive virus infected cells or cells expressing influenza A virus ...

journal_title：Journal of virology

authors： Ren Y,Li C,Feng L,Pan W,Li L,Wang Q,Li J,Li N,Han L,Zheng X,Niu X,Sun C,Chen L

更新日期：2015-10-14 00:00:00

abstract：:The potential role of T cells in the control of human papillomavirus type 6 (HPV-6) infections is an appealing premise, but their actual role has been sparsely investigated. Since HPV-6 infections are confined to the epithelium, such an investigation should focus on the T cells present at the site of infection (i.e., ...

journal_title：Journal of virology

authors： Hong K,Greer CE,Ketter N,Van Nest G,Paliard X

更新日期：1997-09-01 00:00:00

abstract：:Hepatitis C virus (HCV) replicates through an error-prone process that may support the evolution of genetic variants resistant to the host cell antiviral response and interferon (IFN)-based therapy. We evaluated HCV-IFN interactions within a long-term culture system of Huh7 cell lines harboring different variants of a...

journal_title：Journal of virology

authors： Sumpter R Jr,Wang C,Foy E,Loo YM,Gale M Jr

更新日期：2004-11-01 00:00:00

abstract：:Autophagy is now known to be an essential component of host innate and adaptive immunity. Several herpesviruses have developed various strategies to evade this antiviral host defense. Herpes simplex virus 1 (HSV-1) blocks autophagy in fibroblasts and in neurons, and the ICP34.5 protein is important for the resistance ...

journal_title：Journal of virology

authors： Lussignol M,Queval C,Bernet-Camard MF,Cotte-Laffitte J,Beau I,Codogno P,Esclatine A

更新日期：2013-01-01 00:00:00

abstract：:The Zaire ebolavirus protein VP24 was previously demonstrated to inhibit alpha/beta interferon (IFN-alpha/beta)- and IFN-gamma-induced nuclear accumulation of tyrosine-phosphorylated STAT1 (PY-STAT1) and to inhibit IFN-alpha/beta- and IFN-gamma-induced gene expression. These properties correlated with the ability of V...

journal_title：Journal of virology

authors： Reid SP,Valmas C,Martinez O,Sanchez FM,Basler CF

更新日期：2007-12-01 00:00:00

abstract：:Ebola virus (EBOV) continues to pose a significant threat to human health, as evidenced by the 2013-2016 epidemic in West Africa and the ongoing outbreak in the Democratic Republic of the Congo. EBOV causes hemorrhagic fever, organ damage, and shock culminating in death, with case fatality rates as high as 90%. This h...

journal_title：Journal of virology

authors： Jankeel A,Menicucci AR,Woolsey C,Fenton KA,Mendoza N,Versteeg K,Cross RW,Geisbert TW,Messaoudi I

更新日期：2020-05-18 00:00:00

abstract：:Venezuelan equine encephalitis (VEE) virus antigenic subtypes and varieties are considered either epidemic/epizootic or enzootic. In addition to epidemiological differences between the epidemic and enzootic viruses, several in vitro and in vivo laboratory markers distinguishing the viruses have been identified, includ...

journal_title：Journal of virology

authors： Powers AM,Brault AC,Kinney RM,Weaver SC

更新日期：2000-05-01 00:00:00

abstract：:The pneumopathogenicity of a trypsin-sensitive revertant of Sendai virus, TSrev-58, which was derived from a trypsin-resistant mutant, TR-5, was examined in mice. In comparison with TR-5, the revertant had a single amino acid substitution at residue 116 (Ile----Arg) on F protein, which was the cleavage site, and had t...

journal_title：Journal of virology

authors： Mochizuki Y,Tashiro M,Homma M

更新日期：1988-08-01 00:00:00

abstract：:In this study, we characterized the viral determinants of coreceptor usage in relation to susceptibility to antibody-mediated neutralization or enhancement of infectivity by using chimeras of three highly related human immunodeficiency virus type 1 (HIV-1) isolates of different phenotypes. We found that the V3 region ...

journal_title：Journal of virology

authors： Guillon C,Schutten M,Boers PH,Gruters RA,Osterhaus AD

更新日期：2002-03-01 00:00:00

abstract：:Dengue virus (DENV) is a major global pathogen that causes significant morbidity and mortality in tropical and subtropical areas worldwide. An improved understanding of the regions within the DENV genome and its encoded proteins that are required for the virus replication cycle will expedite the development of urgentl...

journal_title：Journal of virology

authors： Eyre NS,Johnson SM,Eltahla AA,Aloi M,Aloia AL,McDevitt CA,Bull RA,Beard MR

更新日期：2017-11-14 00:00:00

abstract：:Cell cycle progression during cytomegalovirus infection was investigated by fluorescence-activated cell sorter (FACS) analysis of the DNA content in growth-arrested as well as serum-stimulated human fibroblasts. Virus-infected cells maintained in either low (0.2%) or high (10%) serum failed to progress into S phase an...

journal_title：Journal of virology

authors： Dittmer D,Mocarski ES

更新日期：1997-02-01 00:00:00

abstract：UNLABELLED:Uracil DNA glycosylases (UNG) are highly conserved proteins that preserve DNA fidelity by catalyzing the removal of mutagenic uracils. All herpesviruses encode a viral UNG (vUNG), and yet the role of the vUNG in a pathogenic course of gammaherpesvirus infection is not known. First, we demonstrated that the v...

journal_title：Journal of virology

authors： Minkah N,Macaluso M,Oldenburg DG,Paden CR,White DW,McBride KM,Krug LT

更新日期：2015-03-01 00:00:00

abstract：:The parechoviruses differ in many biological properties from other picornaviruses, and their replication strategy is largely unknown. In order to identify the viral RNA replication complex in human parechovirus type 1 (HPEV-1)-infected cells, we located viral protein and RNA in correlation to virus-induced membrane al...

journal_title：Journal of virology

authors： Krogerus C,Egger D,Samuilova O,Hyypiä T,Bienz K

更新日期：2003-08-01 00:00:00

abstract：:The human T-cell leukemia virus type 1 (HTLV-1) envelope protein is required for virus spread. This study further characterizes the role of the envelope protein in HTLV-1 immortalization. Viruses with single amino acid substitutions within the SU protein at residue 75, 81, 95, 101, 105, or 195 or with a C-terminal cyt...

journal_title：Journal of virology

authors： Tsukahara T,Wielgosz MM,Ratner L

更新日期：2001-10-01 00:00:00

abstract：:The association of newly synthesized vesicular stomatitis virus proteins into nucleocapsid structures was examined in a cell-free system that supports concurrent viral protein synthesis, transcription, and RNA replication. The vesicular stomatitis virus proteins synthesized by this system associated with the newly rep...

journal_title：Journal of virology

authors： Patton JT,Davis NL,Wertz GW

更新日期：1983-01-01 00:00:00