External validation of the systemic immune-inflammation index as a prognostic factor in metastatic renal cell carcinoma and its implementation within the international metastatic renal cell carcinoma database consortium model.

abstract：BACKGROUND:Recent studies have shown that immune-related adverse events (irAEs) caused by immune checkpoint inhibitors (ICIs) were correlated with favorable clinical outcome in patients with melanoma. However, in metastatic renal cell carcinoma (mRCC) patients, there have been few reports about the correlation between ...

journal_title：International journal of clinical oncology

authors： Kato T,Nagahara A,Kawamura N,Nakata W,Soda T,Matsuzaki K,Hatano K,Kawashima A,Ujike T,Imamura R,Nishimura K,Takada S,Tsujihata M,Yamaguchi S,Takao T,Nishimura K,Nonomura N,Uemura M

更新日期：2021-01-20 00:00:00

abstract：:A 76-year old woman presented with a large inguino-crural mass, multiple abdominal lymphoadenopathies, and neurological signs of spinal cord compression, first diagnosed as large-cell non-Hodgkin lymphoma. At subsequent clinical workup, a diagnosis of granulocytic sarcoma with meningeal involvement was made. Unfortuna...

journal_title：International journal of clinical oncology

authors： Balleari E,Panarello S,Capello E,Grosso M,Passalia C,Pitto P,Raggi F,Roccatagliata L,Cabiddu F,Ghio R

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:This study searched for extra capsular tumour spread (ECS) as a prognostic factor for recurrence in terms of Disease Free Survival (DFS) and Overall Survival (OS). PATIENTS AND METHODS:For this study, from a retrospective database of the Doubs cancer registry, 823 eligible women with node positive breast ca...

journal_title：International journal of clinical oncology

authors： Dobi E,Bazan F,Dufresne A,Demarchi M,Villanueva C,Chaigneau L,Montcuquet P,Ivanaj A,Sautière JL,Maisonnette-Escot Y,Cals L,Algros MP,Woronoff AS,Pivot X

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Six months of adjuvant chemotherapy is regarded as the standard of care for patients with stage III colon cancer. However, whether longer treatment can improve prognosis has not been fully investigated. We conducted a phase III study comparing 6 and 12 months of adjuvant capecitabine chemotherapy for stage I...

journal_title：International journal of clinical oncology

authors： Suto T,Ishiguro M,Hamada C,Kunieda K,Masuko H,Kondo K,Ishida H,Nishimura G,Sasaki K,Morita T,Hazama S,Maeda K,Mishima H,Ike H,Sadahiro S,Sugihara K,Okajima M,Saji S,Sakamoto J,Tomita N

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:We designed an outpatient regimen consisting of fractional cisplatin in combination with S-1, a novel oral fluoropyrimidine derivative for the treatment of recurrent or advanced gastric cancer and conducted a phase I study to determine the dose limiting toxicities (DLTs) and recommended dose (RD). METHODS:E...

journal_title：International journal of clinical oncology

authors： Shimoyama S,Imamura K,Hiki N,Yamaguchi H,Mafune K,Kaminishi M

更新日期：2005-08-01 00:00:00

abstract：:Combination chemotherapy with cisplatin and pemetrexed is the most active first-line regimen for malignant pleural mesothelioma (MPM). However, no drugs have been approved for second-line treatment of MPM, with effective regimens remaining to be identified for patients in relapse. We have now evaluated the combination...

journal_title：International journal of clinical oncology

authors： Hayashi H,Okamoto I,Ichikawa Y,Miyazaki M,Yoshioka H,Kunimasa K,Nakagawa K

更新日期：2010-10-01 00:00:00

abstract：:We report a patient with avascular necrosis of the bilateral femoral head resulting from long-term steroid administration for radiation pneumonitis that occurred after tangential irradiation of the breast. The patient was a 50-year-old postmenopausal woman with breast cancer, stage IIIB (T4bN0M0) in the right C area. ...

journal_title：International journal of clinical oncology

authors： Kosaka Y,Mitsumori M,Araki N,Yamauchi C,Nagata Y,Hiraoka M,Kodama H

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Data supporting the safety and feasibility of laparoscopic total proctocolectomy with ileal pouch-anal anastomosis (TPC-IPAA) and total colectomy with ileorectal anastomosis (TC-IRA) for patients with familial adenomatous polyposis (FAP) are limited. The aim of this study was to clarify the feasibility and m...

journal_title：International journal of clinical oncology

authors： Konishi T,Ishida H,Ueno H,Kobayashi H,Hinoi T,Inoue Y,Ishida F,Kanemitsu Y,Yamaguchi T,Tomita N,Matsubara N,Watanabe T,Sugihara K

更新日期：2016-10-01 00:00:00

abstract：:We present the case of a 62-year-old Japanese man whose histological diagnosis was adenoendocrine cell carcinoma of the gallbladder at autopsy, but whose antemortem diagnosis was squamous cell carcinoma. The patient was admitted to hospital with complaints of occasional vomiting and abdominal pain. Abdominal computed ...

journal_title：International journal of clinical oncology

authors： Taniguchi H,Sakagami J,Suzuki N,Hasegawa H,Shinoda M,Tosa M,Baba T,Yasuda H,Kataoka K,Yoshikawa T

更新日期：2009-04-01 00:00:00

abstract：PURPOSE:The aim of the present study was to evaluate whether serum alpha-fetoprotein (AFP) and des-gamma-carboxy prothrombin (DCP) trends might be correlated with overall survival rates in patients with recurrent hepatocellular carcinoma (HCC) undergoing trans-catheter arterial chemo-embolization (TACE). METHODS:We pe...

journal_title：International journal of clinical oncology

authors： Arai T,Kobayashi A,Ohya A,Takahashi M,Yokoyama T,Shimizu A,Motoyama H,Furusawa N,Notake T,Kitagawa N,Sakai H,Imamura H,Kadoya M,Miyagawa S

更新日期：2014-10-01 00:00:00

abstract：:A 38-year-old woman underwent mastectomy and axillary lymph node dissection for invasive ductal carcinoma with multiple lymph node involvement. The patient received adriamycin 60 mg/m(2) and cyclophosphamide 600 mg/m(2) followed by weekly paclitaxel 80 mg/m(2) (without interruption) as adjuvant treatment. After receiv...

journal_title：International journal of clinical oncology

authors： Hikino H,Kawashima M,Yamada T,Ozaki N

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Our aim was to study the efficacy and safety of combination chemotherapy with gemcitabine plus cisplatin (GC) for patients with advanced urothelial carcinoma (UC) after failure of methotrexate, vinblastin, adriamycin, and cisplatin (M-VAC) chemotherapy. METHODS:We studied a total of 33 patients with advance...

journal_title：International journal of clinical oncology

authors： Gondo T,Ohori M,Hamada R,Tanaka A,Satake N,Takeuchi H,Nakashima J,Hatano T,Tachibana M

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Hormone receptor status has been one of the most important factors in predicting the response to endocrine therapy in breast cancer patients. However, half of those patients with estrogen receptor-positive tumors do not respond to endocrine therapy. There have been no universal factors for predicting resista...

journal_title：International journal of clinical oncology

authors： Kai K,Nishimura R,Arima N,Miyayama H,Iwase H

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Uterine carcinosarcomas (UCSs) are rare and aggressive tumors. The prognostic factors are not sufficiently known. METHODS:We performed a multi-institutional, retrospective study of women with stage I-IV UCS, diagnosed between 2007 and 2012. Data obtained from medical records included demographic, clinicopat...

journal_title：International journal of clinical oncology

authors： Harano K,Hirakawa A,Yunokawa M,Nakamura T,Satoh T,Nishikawa T,Aoki D,Ito K,Ito K,Nakanishi T,Susumu N,Takehara K,Watanabe Y,Watari H,Saito T

更新日期：2016-02-01 00:00:00

abstract：PURPOSE:In adjuvant settings of human epidermal growth factor receptor 2 (HER2)-positive breast cancer, anthracycline-based chemotherapy followed by taxane and trastuzumab is a standard regimen. Recent studies have reported the use of anthracycline-free adjuvant chemotherapy in selected HER2-positive breast cancer pati...

journal_title：International journal of clinical oncology

authors： Watanuki R,Hayashida T,Kawai Y,Kikuchi M,Nakashoji A,Yokoe T,Toyota T,Seki T,Takahashi M,Kitagawa Y

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Obstructive colorectal cancer (CRC) is an emergency situation with high morbidity and mortality, but long-term outcomes of stage II/III obstructive CRC remain unclear. The aim of this study was to evaluate prognostic factors, including colorectal obstruction. METHODS:Data were retrospectively reviewed from ...

journal_title：International journal of clinical oncology

authors： Okuda Y,Shimura T,Yamada T,Hirata Y,Yamaguchi R,Sakamoto E,Kataoka H

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Based on the results of the SPIRITS trial, combination chemotherapy of S-1 plus cisplatin (SP) is now considered the standard treatment for patients with advanced gastric cancer (AGC) in Japan. On the other hand, several non-Japanese studies have shown the efficacy of capecitabine plus cisplatin (XP), which ...

journal_title：International journal of clinical oncology

authors： Shitara K,Sawaki A,Matsuo K,Kondo C,Takahari D,Ura T,Tajika M,Niwa Y,Muro K

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:To avoid the loss of fertility, chemotherapy should be chosen as an adjuvant treatment after trachelectomy. Our study evaluated the effectiveness and safety of adjuvant chemotherapy after abdominal trachelectomy for cervical cancer. METHODS:Our institutional review board approved this clinical study, and in...

journal_title：International journal of clinical oncology

authors： Okugawa K,Yahata H,Sonoda K,Kodama K,Yagi H,Ohgami T,Yasunaga M,Onoyama I,Kaneki E,Asanoma K,Kobayashi H,Kato K

更新日期：2021-01-01 00:00:00

abstract：:Ovarian cancer is the leading cause of death in women with gynecological cancer. Most patients are diagnosed at an advanced stage with a poor prognosis. Currently, surgical tumor debulking followed by chemotherapy based on platinum and taxane is the standard treatment for advanced disease. However, these patients rema...

journal_title：International journal of clinical oncology

authors： Itamochi H,Kigawa J

更新日期：2012-10-01 00:00:00

abstract：:Total gastrectomy and chemotherapy with S-1 after surgery were performed in a 50-year-old woman with gastric cancer associated with acquired immunodeficiency syndrome (AIDS). She was given a diagnosis of gastric cancer at the lesser curvature of the body of the stomach, and distal gastrectomy was performed in December...

journal_title：International journal of clinical oncology

authors： Suzuki R,Ariizumi S,Araida T,Hayashi K,Yamamoto M

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Indocyanine green (ICG), an agent for measuring liver function, becomes fluorescent under near-infrared (NIR) light after binding to serum proteins. Hepatocellular carcinoma (HCC) with a deposit of preoperatively administered ICG becomes clearly detectable under ICG fluorography; however, it remains unclear ...

journal_title：International journal of clinical oncology

authors： Morita Y,Sakaguchi T,Unno N,Shibasaki Y,Suzuki A,Fukumoto K,Inaba K,Baba S,Takehara Y,Suzuki S,Konno H

更新日期：2013-04-01 00:00:00

abstract：:Among head and neck squamous cell carcinoma (HNSCC), the incidence of oropharyngeal SCC (OPSCC) is increasing in contrast to carcinoma with origin in other subsites. Human papillomavirus (HPV) is now recognized as a significant risk factor of the carcinogenesis of OPSCC. The HPV-related OPSCC patients tend to be relat...

journal_title：International journal of clinical oncology

authors： Okami K

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Neuroendocrine carcinoma (NEC) of the esophagus and the stomach is aggressive. The purpose of this study was to determine the optimal therapeutic strategy. METHODS:Both clinicopathological factors and treatment results were examined in 34 patients with immunohistochemically diagnosed NEC of the upper gastro...

journal_title：International journal of clinical oncology

authors： Morita M,Taguchi K,Kagawa M,Nakanoko T,Uehara H,Sugiyama M,Ota M,Ikebe M,Sugimachi K,Esaki T,Toh Y

更新日期：2020-05-01 00:00:00

abstract：:Poorly differentiated neuroendocrine carcinoma has a poor prognosis, especially when associated with distant metastasis. A 60-year-old man was admitted to a private hospital because of dyspnea at work in 2007. Computed tomography revealed lung infarction and a right adrenal tumor sized 12 cm in diameter that was tight...

journal_title：International journal of clinical oncology

authors： Ochiai T,Komiyama S,Ikoma H,Kubota T,Nakanishi M,Ichikawa D,Kikuchi S,Fujiwara H,Sakakura C,Kokuba Y,Sonoyama T,Otsuji E

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:To analyze the impact of sunitinib treatment on health-related quality of life (HRQOL) in Japanese patients with metastatic renal cell carcinoma (mRCC). METHODS:This study prospectively included 90 consecutive patients with mRCC treated with sunitinib for at least 3 months. HRQOL in these patients was asses...

journal_title：International journal of clinical oncology

authors： Miyake H,Harada K,Kusuda Y,Fujisawa M

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Some childhood cancer survivors experience employment difficulties. This study aimed to describe pediatric brain-tumor survivors' employment status. METHODS:A cross-sectional, observational study was conducted, with questionnaires distributed to 101 pediatric brain-tumor survivors (aged 15 years or older) a...

journal_title：International journal of clinical oncology

authors： Sato I,Higuchi A,Yanagisawa T,Murayama S,Kumabe T,Sugiyama K,Mukasa A,Saito N,Sawamura Y,Terasaki M,Shibui S,Takahashi J,Nishikawa R,Ishida Y,Kamibeppu K

更新日期：2018-10-01 00:00:00

abstract：:Research misconduct and fraud in clinical research is an increasing problem facing the scientific community. This problem is expected to increase due to discoveries in central statistical monitoring and with the increase in first-time clinical trial investigators in the increasingly global reach of oncology clinical t...

journal_title：International journal of clinical oncology

authors： Herson J

更新日期：2016-02-01 00:00:00

abstract：BACKGROUNDS:The presence of ≥5 circulating tumor cells (CTCs) in 7.5 ml blood is a poor prognostic marker in metastatic breast cancer (MBC). However, the role of human epidermal growth factor receptor 2 (HER2) status in CTCs is not known. METHODS:We prospectively assessed the prognostic value of this parameter for pat...

journal_title：International journal of clinical oncology

authors： Hayashi N,Nakamura S,Tokuda Y,Shimoda Y,Yagata H,Yoshida A,Ota H,Hortobagyi GN,Cristofanilli M,Ueno NT

更新日期：2012-04-01 00:00:00

abstract：:Pseudoaneurysm complicating osteochondroma is extremely rare. We describe a pseudoaneurysm in the popliteal fossa of a 21-year-old man, occurring 5 years after apparently incomplete resection of an osteochondroma at that site. We found magnetic resonance imaging and magnetic resonance angiography to be of great diagno...

journal_title：International journal of clinical oncology

authors： Otsuka T,Yonezawa M,Kamiyama F,Matusita Y,Matui N

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:We performed a retrospective study to clarify the outcome of stage IB2-IIB patients with bulky cervical cancer who underwent neoadjuvant chemotherapy (NAC) followed by radical hysterectomy and adjuvant treatment. METHODS:Sixty-five patients with bulky stage IB2-IIB cervical cancer, treated at Tottori Univer...

journal_title：International journal of clinical oncology

authors： Uegaki K,Shimada M,Sato S,Deura I,Naniwa J,Sato S,Oishi T,Itamochi H,Harada T,Kigawa J

更新日期：2014-04-01 00:00:00