Assessment of treatment outcomes based on tumor marker trends in patients with recurrent hepatocellular carcinoma undergoing trans-catheter arterial chemo-embolization.

abstract：BACKGROUND:The present study investigated whether treatment with anginex, a novel antiangiogenic peptide, could block re-vascularization after radiation treatment. METHODS:A squamous cell (SCCVII) xenograft tumor mouse model was employed to assess the effects of anginex given post-radiation on tumor growth, microvesse...

journal_title：International journal of clinical oncology

authors： Amano M,Suzuki M,Andoh S,Monzen H,Terai K,Williams B,Song CW,Mayo KH,Hasegawa T,Dings RP,Griffin RJ

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Older or frail patients are often underrepresented in clinical trials for metastatic colorectal cancer (mCRC). We here assessed the efficacy and safety of 5-fluorouracil (5-FU)-leucovorin plus bevacizumab in such patients. METHODS:The study (OGSG 0802) was designed as a single-arm, open-label, multicenter p...

journal_title：International journal of clinical oncology

authors： Ohta T,Kato T,Kawakami H,Miyake Y,Goto M,Iwamoto S,Otsuji T,Nakamura M,Sugimoto N,Okamura S,Kotaka M,Tsujie M,Tokunaga Y,Mishima H,Hata T,Shimokawa T,Kurokawa Y,Satoh T

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Although several studies have reported the incidence of KIT and PDGFRA gene mutations in cutaneous melanomas of Caucasians, only one report is available for Mongoloids, including Japanese. In Japan, melanoma is an uncommon neoplasm compared with countries with Caucasian populations. METHODS:In this study, p...

journal_title：International journal of clinical oncology

authors： Terada T

更新日期：2010-10-01 00:00:00

abstract：:Poorly differentiated neuroendocrine carcinoma has a poor prognosis, especially when associated with distant metastasis. A 60-year-old man was admitted to a private hospital because of dyspnea at work in 2007. Computed tomography revealed lung infarction and a right adrenal tumor sized 12 cm in diameter that was tight...

journal_title：International journal of clinical oncology

authors： Ochiai T,Komiyama S,Ikoma H,Kubota T,Nakanishi M,Ichikawa D,Kikuchi S,Fujiwara H,Sakakura C,Kokuba Y,Sonoyama T,Otsuji E

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Resection of hepatocellular carcinoma (HCC) is potentially curative; however, recurrence is common. To date, few or no effective adjuvant therapies have been adequately investigated. This study evaluates the efficacy of adjuvant iodine-131-lipiodol after hepatic resection through the experience of a single-c...

journal_title：International journal of clinical oncology

authors： Chua TC,Saxena A,Chu F,Butler SP,Quinn RJ,Glenn D,Morris DL

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:We evaluated clinical outcomes of region target focal therapy with high-intensity focused ultrasound (HIFU) for the localized prostate cancer (PCa) based on magnetic resonance imaging-based biopsy and systematic prostate biopsy for Asian. METHODS:We prospectively recruited patients with localized PCa, locat...

journal_title：International journal of clinical oncology

authors： Shoji S,Hiraiwa S,Uemura K,Nitta M,Hasegawa M,Kawamura Y,Hashida K,Hasebe T,Tajiri T,Miyajima A

更新日期：2020-10-01 00:00:00

abstract：:We report four patients with pancreatic metastasis of renal cell carcinoma who were successfully treated with radiation therapy. The patients were one woman and three men with a median age of 55 years (range, 49 to 62 years) who underwent radical nephrectomy for primary renal cell carcinoma. The median interval from n...

journal_title：International journal of clinical oncology

authors： Saito J,Yamanaka K,Sato M,Mori N,Sekii K,Yoshioka T,Itatani H,Nakatsuka S

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:The pasteurized autogenous bone graft (PABG) is a new method to reuse resected and diseased autogenous bones after heat treatment at a comparatively low temperature (60 degrees C-65 degrees C). METHODS:The subjects of this study were ten patients with musculoskeletal tumor who underwent surgery with a PABG ...

journal_title：International journal of clinical oncology

authors： Sakayama K,Kidani T,Fujibuchi T,Kamogawa J,Yamamoto H,Shibata T

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Surgical complication rates of total laryngectomy vary according to the preoperative treatments performed and patient factors. Wound complications after salvage laryngectomy following concurrent chemoradiotherapy (CCRT) were analyzed. METHODS:Eighty-six patients who had undergone total laryngectomy for lary...

journal_title：International journal of clinical oncology

authors： Furuta Y,Homma A,Oridate N,Suzuki F,Hatakeyama H,Suzuki K,Nishioka T,Shirato H,Fukuda S

更新日期：2008-12-01 00:00:00

abstract：PURPOSE:The use of adjuvant treatment has not been sufficiently investigated in duodenal adenocarcinoma. This study evaluated the effect of postoperative radiotherapy (PORT) on survival outcomes in this rare malignancy. METHODS:We identified patients who were diagnosed between 2004 and 2013 in the Surveillance, Epidem...

journal_title：International journal of clinical oncology

authors： Lim YJ,Kim K

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:We performed a multicenter longitudinal study using our neck dissection questionnaire (NDQ) and arm abduction test (AAT) to assess the impact of rehabilitation and surgical modification on postoperative quality of life (QOL). METHODS:Patients who had undergone neck dissection for the treatment of head and n...

journal_title：International journal of clinical oncology

authors： Nibu K,Ebihara Y,Ebihara M,Kawabata K,Onitsuka T,Fujii T,Saikawa M

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:To avoid the loss of fertility, chemotherapy should be chosen as an adjuvant treatment after trachelectomy. Our study evaluated the effectiveness and safety of adjuvant chemotherapy after abdominal trachelectomy for cervical cancer. METHODS:Our institutional review board approved this clinical study, and in...

journal_title：International journal of clinical oncology

authors： Okugawa K,Yahata H,Sonoda K,Kodama K,Yagi H,Ohgami T,Yasunaga M,Onoyama I,Kaneki E,Asanoma K,Kobayashi H,Kato K

更新日期：2021-01-01 00:00:00

abstract：:We report a patient with avascular necrosis of the bilateral femoral head resulting from long-term steroid administration for radiation pneumonitis that occurred after tangential irradiation of the breast. The patient was a 50-year-old postmenopausal woman with breast cancer, stage IIIB (T4bN0M0) in the right C area. ...

journal_title：International journal of clinical oncology

authors： Kosaka Y,Mitsumori M,Araki N,Yamauchi C,Nagata Y,Hiraoka M,Kodama H

更新日期：2006-12-01 00:00:00

abstract：:We present two cases of advanced ovarian cancer treated with neoadjuvant chemotherapy with standard tri-weekly carboplatin and paclitaxel. Therapy was converted to weekly regimens because of disease progression, resulting in disease response. Weekly regimens could overcome drug resistance and this strategy should be a...

journal_title：International journal of clinical oncology

authors： Marchetti C,Bellati F,Musella A,Napoletano C,Perniola G,Di Donato V,Pignata S,Nuti M,Panici PB

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Recombinant human soluble thrombomodulin (rTM) has been established and introduced in the clinic as a standard treatment for disseminated intravascular coagulation (DIC). However, the efficacy and safety of rTM for DIC associated with solid tumors (DIC-STs) have not been fully established. Here, we performed...

journal_title：International journal of clinical oncology

authors： Ouchi K,Takahashi S,Chikamatsu S,Ito S,Takahashi Y,Kawai S,Okita A,Kasahara Y,Okada Y,Imai H,Komine K,Saijo K,Takahashi M,Shirota H,Takahashi M,Gamoh M,Ishioka C

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:We evaluated the longer-term efficacy and safety of concurrent chemoradiotherapy (CCRT) incorporating high-dose-rate intracavitary brachytherapy (HDR-ICBT) with a lower cumulative radiotherapy (RT) protocol and analyzed prognostic risk factors for survival among patients with FIGO stage III-IVA squamous cell...

journal_title：International journal of clinical oncology

authors： Kudaka W,Nagai Y,Toita T,Inamine M,Asato K,Nakamoto T,Wakayama A,Ooyama T,Tokura A,Murayama S,Aoki Y

更新日期：2013-10-01 00:00:00

abstract：:When total mesorectal excision (TME) is accurately performed, dysfunction, theoretically, does not occur. However, there are differences among individuals in the running patterns and the volumes of nerve fibers, and if obesity or a narrow pelvis is present, nerve identification is difficult. Currently, the rate of uri...

journal_title：International journal of clinical oncology

authors： Moriya Y

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the prognostic veracity for disease-specific survival (DSS) of the eighth edition of the American Joint Committee on Cancer/Union for International Cancer Control tumor-node-metastasis staging system (TNM-8) compared with the seventh edition (TNM-7) in a Chinese populati...

journal_title：International journal of clinical oncology

authors： Zhi J,Wu Y,Hu L,Zhao J,Liu H,Ruan X,Hou X,Zhang J,Zheng X,Gao M

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Neuroendocrine carcinoma (NEC) of the esophagus and the stomach is aggressive. The purpose of this study was to determine the optimal therapeutic strategy. METHODS:Both clinicopathological factors and treatment results were examined in 34 patients with immunohistochemically diagnosed NEC of the upper gastro...

journal_title：International journal of clinical oncology

authors： Morita M,Taguchi K,Kagawa M,Nakanoko T,Uehara H,Sugiyama M,Ota M,Ikebe M,Sugimachi K,Esaki T,Toh Y

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to assess the ability of fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) to detect upper urinary tract urothelial carcinomas (UTUC) compared with pathological examination of tissues obtained by ureteroscopic biopsy and split cytologic analysis of...

journal_title：International journal of clinical oncology

authors： Asai S,Fukumoto T,Tanji N,Miura N,Miyagawa M,Nishimura K,Yanagihara Y,Shirato A,Miyauchi Y,Kikugawa T,Yokoyama M

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Our aim was to study the efficacy and safety of combination chemotherapy with gemcitabine plus cisplatin (GC) for patients with advanced urothelial carcinoma (UC) after failure of methotrexate, vinblastin, adriamycin, and cisplatin (M-VAC) chemotherapy. METHODS:We studied a total of 33 patients with advance...

journal_title：International journal of clinical oncology

authors： Gondo T,Ohori M,Hamada R,Tanaka A,Satake N,Takeuchi H,Nakashima J,Hatano T,Tachibana M

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:The prognostic factors of pulmonary metastasectomy in patients with osteosarcoma and soft tissue sarcoma remain controversial. The purpose of our analysis was to explore the prognostic factors and outcomes of patients with osteosarcoma and soft tissue sarcoma who underwent pulmonary metastasectomy at our ins...

journal_title：International journal of clinical oncology

authors： Yamamoto Y,Kanzaki R,Kanou T,Ose N,Funaki S,Shintani Y,Minami M,Outani H,Takenaka S,Hamada K,Yoshikawa H,Okumura M

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the prognostic role of the pretreatment neutrophil-to-lymphocyte ratio (NLR) as a predictive marker prior to treatment of cervical cancer with radiation therapy (RT) alone or concurrent chemoradiation therapy (CCRT). METHODS:Fifty-six patients with squamous cell carc...

journal_title：International journal of clinical oncology

authors： Mizunuma M,Yokoyama Y,Futagami M,Aoki M,Takai Y,Mizunuma H

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:It is expected that cell-free and concentrated ascites reinfusion therapy (CART) will relieve the symptoms caused by ascites. To date, however, no report of objective changes in patients' symptoms has been published. We have therefore evaluated symptom management by CART. METHODS:From April 2011 to July 201...

journal_title：International journal of clinical oncology

authors： Ito T,Hanafusa N,Iwase S,Noiri E,Nangaku M,Nakagawa K,Miyagawa K

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Several factors related to the immune system, such as a history of allergies and virus infections, may be associated with acute lymphoblastic leukemia (ALL). The purpose of this study was to analyze whether the presence of atopic diseases and previous infection with parvovirus B19 and Epstein-Barr virus (EBV...

journal_title：International journal of clinical oncology

authors： da Conceição Nunes J,de Araujo GV,Viana MT,Sarinho ES

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Diagnosis of secondary ovarian tumors originating from colorectal cancer has previously been based upon history of malignancy and radiological findings of bilateral masses with a "stained glass appearance." The purpose of this study was to perform a detailed investigation of the radiological and macroscopic ...

journal_title：International journal of clinical oncology

authors： Kato MK,Shida D,Yoneoka Y,Yoshida H,Miyasaka N,Kanemitsu Y,Kato T

更新日期：2020-09-01 00:00:00

abstract：:Despite major improvements in the treatment of early-stage breast cancer over the past 15 years, many controversies exist surrounding the optimal adjuvant therapies for these patients. Adjuvant chemotherapy has been demonstrated to reduce recurrence and improve mortality, but questions persist as to what is the optima...

journal_title：International journal of clinical oncology

authors： Gradishar WJ,O'Regan RM

更新日期：2003-08-01 00:00:00

abstract：PURPOSE:Boron neutron capture therapy (BNCT) is among the radiation treatments known to have a selective lethal effect on tumor cells. This study summarizes the tumor responses and the acute and late adverse effects of BNCT in the treatment of patients with both recurrent and newly diagnosed T4 salivary gland carcinoma...

journal_title：International journal of clinical oncology

authors： Aihara T,Morita N,Kamitani N,Kumada H,Ono K,Hiratsuka J,Harada T

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:The purpose of this study was to determine if quantitative SUV-related, volumetric FDG PET parameters, and texture features (SPs, VPs, and TFs, respectively) were useful to evaluate and predict response and recurrence after chemotherapy in follicular lymphoma (FL). METHODS:Pre- and posttreatment FDG PET examin...

journal_title：International journal of clinical oncology

authors： Tatsumi M,Isohashi K,Matsunaga K,Watabe T,Kato H,Kanakura Y,Hatazawa J

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Gastric cancer (GC) patients are usually diagnosed in advanced stages which results in high mortality. This study aimed to identify novel circulating miRNAs as biomarkers for the early detection of GC. METHODS:Candidate miRNA was identified after integrated analysis of two Gene Expression Omnibus (GEO) data...

journal_title：International journal of clinical oncology

authors： Shi Y,Wang Z,Zhu X,Chen L,Ma Y,Wang J,Yang X,Liu Z

更新日期：2020-01-01 00:00:00