Treatment strategies for neuroendocrine carcinoma of the upper digestive tract.

abstract：BACKGROUND:Lip carcinomas are rare oral tumors, and there have been few reports of lip carcinoma in Japan. METHODS:Of 914 patients with oral carcinomas treated between January 1980 and December 1998, 12 (1.3%) had lip carcinoma and 5 (0.5%) had lip mucosal carcinoma. We investigated the clinicopathological features of...

journal_title：International journal of clinical oncology

authors： Ogura I,Amagasa T,Iwaki H,Kijima T,Kurabayashi T,Yoshimasu H

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:We retrospectively investigated the efficacy and safety profile of weekly low-dose docetaxel (DTX) with estramustine in comparison with triweekly standard-dose DTX treatment for Japanese patients with castration-resistant prostate cancer (CRPC). METHODS:Between April 2002 and January 2011, 75 CRPC patients ...

journal_title：International journal of clinical oncology

authors： Nakai Y,Nishimura K,Nakayama M,Uemura M,Takayama H,Nonomura N,Tsujimura A,Osaka CRPC Clinical Study Collaboration.

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Impact of R1 (microscopically margin-positive) resection on survival of patients with hepatoblastoma (HB) remains debatable. This study aimed to compare the long-term outcomes of R0 (microscopically margin-negative) and R1 resection for HB in children after hepatectomy. METHODS:We retrospectively reviewed f...

journal_title：International journal of clinical oncology

authors： Ren X,Li H,Diao M,Xu H,Li L

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Pulmonary wedge resection is an option for lung cancer patients with limited cardiopulmonary preservation. As the impact of underlying lung status on the prognosis of such patients remains unclear, we assessed this issue. METHODS:A total of 149 borderline surgical candidates with localized lung cancer who h...

journal_title：International journal of clinical oncology

authors： Kawaguchi T,Sawabata N,Miura S,Kawai N,Yasukawa M,Tojo T,Taniguchi S

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Gastric cancer (GC) patients are usually diagnosed in advanced stages which results in high mortality. This study aimed to identify novel circulating miRNAs as biomarkers for the early detection of GC. METHODS:Candidate miRNA was identified after integrated analysis of two Gene Expression Omnibus (GEO) data...

journal_title：International journal of clinical oncology

authors： Shi Y,Wang Z,Zhu X,Chen L,Ma Y,Wang J,Yang X,Liu Z

更新日期：2020-01-01 00:00:00

abstract：:Bile duct hamartomas, also known as von Meyenburg complexes, are benign neoplasms consisting of cystic dilatation of the bile duct surrounded by fibrous stroma. We report a rare case in a 60-year-old man who presented with coexistent von Meyenburg complex and esophageal carcinoma. Preoperative computed tomography did ...

journal_title：International journal of clinical oncology

authors： Mimatsu K,Oida T,Kawasaki A,Aramaki O,Kuboi Y,Katsura Y,Amano S

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Recurrent or persistent clear cell carcinoma (CCC) of the ovary is particularly chemotherapy resistant. The purpose of this study was to review our extensive institutional experiences with recurrent or persistent CCC with the aim of finding a more effective chemotherapy regimen. METHODS:The medical records ...

journal_title：International journal of clinical oncology

authors： Yoshino K,Enomoto T,Fujita M,Ueda Y,Kimura T,Kobayashi E,Tsutsui T,Kimura T

更新日期：2013-02-01 00:00:00

abstract：INTRODUCTION:We retrospectively evaluated the blood coagulation activity using the D-dimer level in the early period after gastrectomy and investigated whether postoperative hypercoagulation affects tumor recurrence and long-term survival in gastric cancer patients. METHODS:The study involved 650 patients who underwen...

journal_title：International journal of clinical oncology

authors： Hara K,Aoyama T,Hayashi T,Nakazono M,Nagasawa S,Shimoda Y,Kumazu Y,Numata M,Yamada T,Tamagawa H,Shiozawa M,Morinaga S,Yukawa N,Rino Y,Masuda M,Ogata T,Oshima T

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Cyclin E and p27 play pivotal roles in cancer development and progression. We investigated whether the prognosis in cases of non-small cell lung cancer without lymph node metastases that underwent complete resection could be associated with tissue expression of cyclin E, p27, and Ki-67. METHODS:Tumors from ...

journal_title：International journal of clinical oncology

authors： Takahashi S,Kamata Y,Tamo W,Koyanagi M,Hatanaka R,Yamada Y,Tsushima T,Takaya S,Fukuda I

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Recent studies have shown that somatic mutations in the AT-rich interactive domain 1A (SWI-like) gene (ARID1A) are the most common genetic changes in clear cell carcinoma of the ovary (CCC). A gene mutation of ARID1A was found in approximately half of CCC cases, and led to absence of the encoded protein and ...

journal_title：International journal of clinical oncology

authors： Itamochi H,Oumi N,Oishi T,Shoji T,Fujiwara H,Sugiyama T,Suzuki M,Kigawa J,Harada T

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Constipation is a common side effect of opioid therapy. An observational study of opioid-induced constipation (OIC) in Japanese patients with cancer (OIC-J) included 212 patients with various tumor types. This post hoc analysis of OIC-J evaluated a subgroup of patients with gastrointestinal (GI) cancer. MET...

journal_title：International journal of clinical oncology

authors： Harada T,Imai H,Fumita S,Noriyuki T,Gamoh M,Okamoto M,Akashi Y,Kizawa Y,Tokoro A

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Pulmonary metastasectomy in patients with renal cell carcinoma (RCC) remains controversial. The purpose of our analysis was to explore the outcome of patients with RCC who underwent pulmonary metastasectomy at our institution. METHODS:We reviewed data on 25 patients who underwent resection of lung metastasi...

journal_title：International journal of clinical oncology

authors： Kawashima A,Nakayama M,Oka D,Sato M,Hatano K,Mukai M,Nagahara A,Nakai Y,Takayama H,Inoue M,Shiono H,Nishimura K,Okumura M,Nonomura N

更新日期：2011-12-01 00:00:00

abstract：:We report four patients with pancreatic metastasis of renal cell carcinoma who were successfully treated with radiation therapy. The patients were one woman and three men with a median age of 55 years (range, 49 to 62 years) who underwent radical nephrectomy for primary renal cell carcinoma. The median interval from n...

journal_title：International journal of clinical oncology

authors： Saito J,Yamanaka K,Sato M,Mori N,Sekii K,Yoshioka T,Itatani H,Nakatsuka S

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the prognostic veracity for disease-specific survival (DSS) of the eighth edition of the American Joint Committee on Cancer/Union for International Cancer Control tumor-node-metastasis staging system (TNM-8) compared with the seventh edition (TNM-7) in a Chinese populati...

journal_title：International journal of clinical oncology

authors： Zhi J,Wu Y,Hu L,Zhao J,Liu H,Ruan X,Hou X,Zhang J,Zheng X,Gao M

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Obstructive colorectal cancer (CRC) is an emergency situation with high morbidity and mortality, but long-term outcomes of stage II/III obstructive CRC remain unclear. The aim of this study was to evaluate prognostic factors, including colorectal obstruction. METHODS:Data were retrospectively reviewed from ...

journal_title：International journal of clinical oncology

authors： Okuda Y,Shimura T,Yamada T,Hirata Y,Yamaguchi R,Sakamoto E,Kataoka H

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Although many studies have already shown that lymph node metastasis is one of the major prognostic factors for cervical cancer, the therapeutic significance of para-aortic lymphadenectomy for the surgical treatment of cervical cancer remains controversial. METHODS:A total of 308 patients diagnosed with stag...

journal_title：International journal of clinical oncology

authors： Tsuruga T,Fujimoto A,Kawana K,Mori M,Hasumi Y,Kino N,Tomio K,Miura S,Tanikawa M,Sone K,Miyamoto Y,Ikeda Y,Kojima S,Adachi K,Nagasaka K,Matsumoto Y,Arimoto T,Oda K,Nakagawa S,Horie K,Yasugi T,Yokota H,Osuga Y,

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:This single-arm, multicenter, phase-II trial evaluated the efficacy and safety of hepatic arterial infusion chemotherapy (HAIC) using fine-powder cisplatin and iodized-oil suspension in patients with intermediate- and advanced-stage [Barcelona Clinic Liver Cancer (BCLC) stage-B and stage-C] hepatocellular carci...

journal_title：International journal of clinical oncology

authors： Takaki H,Yamakado K,Tsurusaki M,Yasumoto T,Baba Y,Narimatsu Y,Shimohira M,Yamaguchi M,Matsuo K,Inaba Y,Mikami K,Watanabe R,Nishida N,Anai H,Kakizawa H,Hirota S

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:We aimed to determine the frequency of fibromyalgia syndrome (FM) in operated breast cancer patients and to research the relationship between FM and the severity of fatigue and quality of life in these breast cancer patients. METHODS:The demographic data of 101 operated breast cancer patients were recorded....

journal_title：International journal of clinical oncology

authors： Akkaya N,Atalay NS,Selcuk ST,Alkan H,Catalbas N,Sahin F

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:This study was conducted to determine the efficacy and safety of low-dose chemotherapy with methotrexate (MTX) and vinblastine (VBL) for patients with desmoid tumors refractory to meloxicam treatment, focusing in particular on the relationship between the efficacy of this chemotherapy and catenin β-1 (CTNNB1...

journal_title：International journal of clinical oncology

authors： Nishida Y,Tsukushi S,Urakawa H,Hamada S,Kozawa E,Ikuta K,Ando Y,Ishiguro N

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:We previously reported the feasibility of short-term low-volume hydration in patients with advanced lung cancer who received cisplatin-based chemotherapy (Jpn J Clin Oncol 2013). We sought to determine the clinical usefulness of a more convenient hydration method, evaluating the safety and efficacy of shorter...

journal_title：International journal of clinical oncology

authors： Ninomiya K,Hotta K,Hisamoto-Sato A,Ichihara E,Gotoda H,Morichika D,Tamura T,Kayatani H,Minami D,Kubo T,Tabata M,Tanimoto M,Kiura K

更新日期：2016-02-01 00:00:00

abstract：:We report a patient with avascular necrosis of the bilateral femoral head resulting from long-term steroid administration for radiation pneumonitis that occurred after tangential irradiation of the breast. The patient was a 50-year-old postmenopausal woman with breast cancer, stage IIIB (T4bN0M0) in the right C area. ...

journal_title：International journal of clinical oncology

authors： Kosaka Y,Mitsumori M,Araki N,Yamauchi C,Nagata Y,Hiraoka M,Kodama H

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to identify the role of Bcl-2 protein and adrenomedullin (AM) expression in relation to apoptosis in the neoplastic changes of squamous epithelium of the uterine cervix. METHODS:Apoptosis in sections of normal cervical epithelium, cervical intraepithelial neoplasia (CIN), and i...

journal_title：International journal of clinical oncology

authors： Li Z,Takeuchi S,Ohara N,Maruo T

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:The role and the optimal measurement method of serum HER2 levels are not defined in patients with metastatic breast cancer (MBC). We prospectively assessed the prognostic value of serum HER2 levels in MBC using two methods, enzyme immunoassay (EIA) and chemiluminescence immunoassay (CLIA). METHODS:We collec...

journal_title：International journal of clinical oncology

authors： Hayashi N,Nakamura S,Tokuda Y,Yagata H,Yoshida A,Ota H,Hortobagyi GN,Cristofanilli M,Ueno NT

更新日期：2012-02-01 00:00:00

abstract：:Ovarian cancer is the leading cause of death in women with gynecological cancer. Most patients are diagnosed at an advanced stage with a poor prognosis. Currently, surgical tumor debulking followed by chemotherapy based on platinum and taxane is the standard treatment for advanced disease. However, these patients rema...

journal_title：International journal of clinical oncology

authors： Itamochi H,Kigawa J

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:To avoid the loss of fertility, chemotherapy should be chosen as an adjuvant treatment after trachelectomy. Our study evaluated the effectiveness and safety of adjuvant chemotherapy after abdominal trachelectomy for cervical cancer. METHODS:Our institutional review board approved this clinical study, and in...

journal_title：International journal of clinical oncology

authors： Okugawa K,Yahata H,Sonoda K,Kodama K,Yagi H,Ohgami T,Yasunaga M,Onoyama I,Kaneki E,Asanoma K,Kobayashi H,Kato K

更新日期：2021-01-01 00:00:00

abstract：:A 74-year-old female was referred to our hospital for non-muscle invasive bladder tumors initially treated at another hospital. Preoperatively, computed tomography and magnetic resonance imaging demonstrated non-muscle invasive bladder tumors and a vaginal tumor. A second transurethral resection of the bladder tumors,...

journal_title：International journal of clinical oncology

authors： Kaneko G,Kikuchi E,Hasegawa M,Miyajima A,Nakagawa K,Kameyama K,Oya M

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Based on the results of the SPIRITS trial, combination chemotherapy of S-1 plus cisplatin (SP) is now considered the standard treatment for patients with advanced gastric cancer (AGC) in Japan. On the other hand, several non-Japanese studies have shown the efficacy of capecitabine plus cisplatin (XP), which ...

journal_title：International journal of clinical oncology

authors： Shitara K,Sawaki A,Matsuo K,Kondo C,Takahari D,Ura T,Tajika M,Niwa Y,Muro K

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Aurora B is a serine-threonine kinase and chromosomal passenger protein involved in the control of chromosome assembly and segregation during mitosis. Aberrant expression of Aurora B has been reported in some tumors, including lung and hepatocellular carcinoma (HCC). We investigated the role of Aurora B expr...

journal_title：International journal of clinical oncology

authors： Tovuu LO,Utsunomiya T,Imura S,Morine Y,Ikemoto T,Arakawa Y,Mori H,Hanaoka J,Kanamoto M,Sugimoto K,Saito Y,Yamada S,Asanoma M,Shimada M

更新日期：2014-08-01 00:00:00

abstract：:Stereotactic body radiation therapy (SBRT) can yield excellent local tumor control, as well as survival benefit comparable to that of surgery for early-stage lung cancer. However, in terms of toxicity, SBRT might lead to fatal radiation pneumonitis. Lung diseases, such as chronic obstructive pulmonary disease (COPD) a...

journal_title：International journal of clinical oncology

authors： Doi H,Nakamatsu K,Nishimura Y

更新日期：2019-08-01 00:00:00

abstract：:5-Fluorouracil (5-FU) has been the most widely accepted and studied chemotherapeutic agent, and many combination chemotherapeutic regimens have been reported. However, until recently, a standard regimen for metastatic gastric cancer had not been established. The combination of S-1 and cisplatin is a good candidate as ...

journal_title：International journal of clinical oncology

authors： Yoshida K,Yamaguchi K,Osada S,Kawaguchi Y,Takahashi T,Sakashita F,Tanaka Y

更新日期：2008-06-01 00:00:00