Abstract:
:The present study was aimed to analyze the effect of ZnO and TiO2 nanoparticles (NPs) on Haemato-immunological parameters in adult Tilapia, Oreochromis mossambicus. The nanoparticles size found as 47 nm and 30 nm for ZnO and TiO2 respectively. The acute toxicity (96 h) of ZnO (LC50: 100-110 ppm) and TiO2 (LC50: 80-90 ppm) NPs were identified by using probit analysis. RBC, Hb and HCT levels decreased in nanoparticles exposed groups resulted in decreased oxygen carrying capacity of RBC and other erythrocyte indices (MCH, MCV, MCHC). Increased WBC, neutrophils & monocytes and decreased lymphocyte levels were observed as increased concentration of the nanoparticles. The results were found as statistically significant (p < 0.05). In conclusion, the present study depicts that ZnO NPs exhibits more toxicity than TiO2 NPs. Nanoparticles presence even in low concentration (ppm) cause damage to the connective tissues of fish, so the existing permissible levels of these nanoparticles in water are need to be revised.
journal_name
Environ Toxicol Pharmacoljournal_title
Environmental toxicology and pharmacologyauthors
Suganthi P,Murali M,Athif P,Sadiq Bukhari A,Syed Mohamed HE,Basu H,Singhal RKdoi
10.1016/j.etap.2018.12.011subject
Has Abstractpub_date
2019-02-01 00:00:00pages
55-61eissn
1382-6689issn
1872-7077pii
S1382-6689(18)30577-5journal_volume
66pub_type
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