Abstract：
:The sensitivity of human lymphocytes from different donors to CdCl2 using a complex of methods for determination of cytotoxicity and genotoxicity was studied. As endpoints for cytotoxicity the mitotic index (MI) and apoptosis were evaluated. To indicate genotoxicity chromosome aberrations test (CA) was used. The results indicate an individual sensitivity of lymphocytes to CdCl2-induced damage, which is directly depending on the concentration (10(-6), 10(-5), 5×10(-5), 10(-4)mol/l) applied. The assessment of the toxic and genotoxic effect using various endpoints allows more complete risk estimation for organisms exposed to heavy metals. The results have direct practical significance for threat evaluation in humans.
journal_name
Environ Toxicol Pharmacoljournal_title
Environmental toxicology and pharmacologyauthors
Gateva S,Jovtchev G,Stergios Mdoi
10.1016/j.etap.2013.03.021subject
Has Abstractpub_date
2013-07-01 00:00:00pages
223-30issue
1eissn
1382-6689issn
1872-7077pii
S1382-6689(13)00081-1journal_volume
36pub_type
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journal_title：Environmental toxicology and pharmacology
pub_type： 杂志文章
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journal_title：Environmental toxicology and pharmacology
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journal_title：Environmental toxicology and pharmacology
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journal_title：Environmental toxicology and pharmacology
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journal_title：Environmental toxicology and pharmacology
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journal_title：Environmental toxicology and pharmacology
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journal_title：Environmental toxicology and pharmacology
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journal_title：Environmental toxicology and pharmacology
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journal_title：Environmental toxicology and pharmacology
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journal_title：Environmental toxicology and pharmacology
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journal_title：Environmental toxicology and pharmacology
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journal_title：Environmental toxicology and pharmacology
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journal_title：Environmental toxicology and pharmacology
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journal_title：Environmental toxicology and pharmacology
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journal_title：Environmental toxicology and pharmacology
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journal_title：Environmental toxicology and pharmacology
pub_type： 杂志文章
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journal_title：Environmental toxicology and pharmacology
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journal_title：Environmental toxicology and pharmacology
pub_type： 杂志文章
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更新日期：2015-03-01 00:00:00
abstract：:Earthworms are an ideal biological model in toxicity assays and environment monitoring studies, especially for the toxicity of pesticides on soil ecosystem. However, There are very little data on the toxicity of triazoles on earthworms despite the fact that such data are critical in assessing their fate and potential ...
journal_title：Environmental toxicology and pharmacology
pub_type： 杂志文章
doi：10.1016/j.etap.2013.02.003
更新日期：2013-05-01 00:00:00
