Fate of psychoactive compounds in wastewater treatment plant and the possibility of their degradation using aquatic plants.

abstract：:The term "angiogenic switch" refers to a time-restricted event during tumor progression where the balance between pro- and anti-angiogenic factors, resulting in the transition from dormant avascularized hyperplasia to outgrowing vascularized tumor and eventually to malignant tumor progression. Targeting angiogenesis a...

journal_title：Environmental toxicology and pharmacology

authors： Senthilkumar K,Venkatesan J,Manivasagan P,Kim SK

更新日期：2013-11-01 00:00:00

abstract：:Lithium, like insulin, activates glycogen synthase and stimulates glucose transport in rat adipocytes. To investigate the effect of dietary overload lithium on glucose metabolism in broiler chickens, one-day-old chicks were fed a basal diet supplemented with 0 (control) or 100mg lithium/kg (overload lithium) for 35day...

journal_title：Environmental toxicology and pharmacology

authors： Bai S,Pan S,Zhang K,Ding X,Wang J,Zeng Q,Xuan Y,Su Z

更新日期：2017-09-01 00:00:00

abstract：:The epothilones, a new class of microtubule-targeting agents, seem to be a very promising alternative to the current strategy of cancer treatment. We have analyzed the aspects of epothilone B (Epo B) on cellular metabolism of tumor (OV-90) and normal (MM 14) ovarian cells. The observed effects were compared with those...

journal_title：Environmental toxicology and pharmacology

authors： Rogalska A,Szula E,Gajek A,Marczak A,Jóźwiak Z

更新日期：2013-09-01 00:00:00

abstract：:Skin is frequently exposed to a variety of environmental and chemical agents that accelerate ageing. External stress such as UV radiations (UVR) and environmental pollutants majorly deteriorate the skin morphology, by activating certain intrinsic factors such as Reactive Oxygen Species (ROS) which trigger the activati...

journal_title：Environmental toxicology and pharmacology

authors： Tanuja Yadav,Mishra S,Das S,Aggarwal S,Rani V

更新日期：2015-01-01 00:00:00

abstract：:Ulcerative colitis (UC) is a disease of increased worldwide prevalence. UC progression is associated with serious complications that leave the patient with considerable health burdens. Nifuroxazide is an oral nitrofuran antibiotic used as antidiarrheal medication. The current study places an emphasis on investigating ...

journal_title：Environmental toxicology and pharmacology

authors： El-Far YM,Elsherbiny NM,El-Shafey M,Said E

更新日期：2020-10-01 00:00:00

abstract：:Cannabis and Mandrax abuse is unique to South Africa; and most research has focused on the socio-economic impact rather than the adverse effects on the developing brain. Therefore, the aim of this study is to determine the effects of Mandrax and Cannabis alone and in combination on the developing brain by using primar...

journal_title：Environmental toxicology and pharmacology

authors： da Silva AA,Bester MJ,Pretorius E

更新日期：2007-01-01 00:00:00

abstract：:The neurotoxicity of monocrotophos (MCP) in the development of the serotonergic nervous system and swimming activity of larvae of the sea urchin, Hemicentrotus pulcherrimus, was examined. Lethal dose 50% of MCP was 43μg/ml. Overall morphology was not affected in larvae that received up to 30μg/ml of MCP soon after fer...

journal_title：Environmental toxicology and pharmacology

authors： Yao D,Ru S,Katow H

更新日期：2010-09-01 00:00:00

abstract：:This study was to appraise the anti-inflammatory and free radical scavenging activities of ethanol extracts of Ilex ficoidea Hemsl (EIFH) and Ilex centrochinensis S.Y. Hu (EICC). Anti-inflammatory activities were evaluated using xylene-induced ear edema and the cotton pellet granuloma tests. Some antioxidants produced...

journal_title：Environmental toxicology and pharmacology

authors： Li L,Zhang Y,Zhang P,Pi H,Ruan H,Wu J

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Sulfur mustard is an alkylating agent which cause to short and long term incapacitations on various organs including lung. There is no definite treatment for lung disorders induced by SM exposure. In the present study, the preventive effect of Zataria multiflora (Z. multiflora) on hematological parameters, o...

journal_title：Environmental toxicology and pharmacology

authors： Khazdair MR,Rajabi O,Balali-Mood M,Beheshti F,Boskabady MH

更新日期：2018-03-01 00:00:00

abstract：:Bisphenol A (BPA) is shown to be the endocrine disruptor that induces reproductive dysfunction in male animals. In this study, we aim to probe the effects of BPA exposure on induction of autophagy in goat Sertoli Cells (gSCs), as well as the relationship between autophagy and apoptosis. Results indicated that exposure...

journal_title：Environmental toxicology and pharmacology

authors： Zhang Y,Han L,Yang H,Pang J,Li P,Zhang G,Li F,Wang F

更新日期：2017-10-01 00:00:00

abstract：:One of the consequence of municipal waste deposition is the production of landfill leachate. Its volume and composition is determined by numerous factors, including waste composition, landfill age and the volume of precipitation. Leachate may contain a number of mineral and organic compounds, the volume of which must ...

journal_title：Environmental toxicology and pharmacology

authors： Przydatek G

更新日期：2019-04-01 00:00:00

abstract：:Effects of aluminum (Al) on membrane properties of excitable cells are not fully understood. Several reports have identified cellular membranes as sensitive targets for Al intoxication. In the present study, we tested the hypothesis that treatment with Al would alter membrane fluidity and potential and these changes w...

journal_title：Environmental toxicology and pharmacology

authors： Johnson VJ,Tsunoda M,Murray TF,Sharma RP

更新日期：2005-02-01 00:00:00

abstract：:Since hypoxia-inducible factor-1α (HIF-1α) is the key transcription factor that enables cells to survive in hypoxia, we have investigated whether an upregulation of HIF-1α prevents the noise-induced hearing loss in BALB/c hybrid mice, which were intraperitoneally injected with CoCl(2) (a HIF-1α inducer) and exposed to...

journal_title：Environmental toxicology and pharmacology

authors： Chung JW,Shin JE,Han KW,Ahn JH,Kim YJ,Park JW,So HS

更新日期：2011-01-01 00:00:00

abstract：:Diethylnitrosamine (DEN) treatment increases the generation of reactive oxygen species (ROS), apoptosis, necrosis and proliferation in the liver. Blueberries (BB; Vaccinium corymbosum L.) contain polyphenols and other active components and have high antioxidant capacities. We investigated the effect of BB pretreatment...

journal_title：Environmental toxicology and pharmacology

authors： Bingül İ,Başaran-Küçükgergin C,Tekkeşin MS,Olgaç V,Doğru-Abbasoğlu S,Uysal M

更新日期：2013-09-01 00:00:00

abstract：:The environmental contaminants pentachlorophenol (PCP) and 4, 4'-dichlorodiphenyltrichloroethane (DDT) are detected in some human blood samples at levels as high as 5 μM (PCP) and 260 nM (DDT). Several cancers are associated with exposures to these contaminants. IL-6 is a pro-inflammatory cytokine that when dysregulat...

journal_title：Environmental toxicology and pharmacology

authors： Martin TJ,Gabure S,Maise J,Snipes S,Peete M,Whalen MM

更新日期：2019-11-01 00:00:00

abstract：:To elucidate the potential thyroid disrupting effects of refuse leachate on females, female goldfish (Carassius auratus) were exposed to 0.5% diluted leachates from each step of a leachate treatment process (i.e. raw leachate before treatment, after membrane bioreactor treatment, and the final treated leachate) for 21...

journal_title：Environmental toxicology and pharmacology

authors： Gong Y,Tian H,Zhang X,Dong Y,Wang W,Ru S

更新日期：2016-12-01 00:00:00

abstract：:Both β-amyloid (Aβ) catabolism and epigenetic regulation play critical roles in the onset of neurodegeneration. The latter also contribute to Pb neurotoxicity. The present study explored the role of epigenetic modifiers and Aβ degradation enzymes in Pb-induced latent effects on Aβ overproduction in vitro. Our results ...

journal_title：Environmental toxicology and pharmacology

authors： Wang Y,Hu Y,Wu Z,Su Y,Ba Y,Zhang H,Li X,Cheng X,Li W,Huang H

更新日期：2019-02-01 00:00:00

abstract：:The dominant lethal assay was utilized to assess the reproductive performance in male mice, possible genetic hazards, and persistent damage of aluminum (Al). Al chloride, AlCl(3), was administered subcutaneously to CD-1 adult male mice at dosages of 0, 7, or 13mg Al/kg body weight/day for 2 weeks of pre-mating periods...

journal_title：Environmental toxicology and pharmacology

authors： Guo CH,Lu YF,Hsu GS

更新日期：2005-07-01 00:00:00

abstract：:Aromatase catalyzes intraneuronal conversion of androgens to estrogens in the hypothalamus-preoptic area at a specific time during development. This local estrogen formation has a central role in sexual differentiation. To investigate the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on sexual differentiation,...

journal_title：Environmental toxicology and pharmacology

authors： Ikeda M,Inukai N,Mitsui T,Sone H,Yonemoto J,Tohyama C,Tomita T

更新日期：2002-01-01 00:00:00

abstract：:The toxicity of fumonisin B(1) (FB(1)) was investigated in male mdr1a/1b double knockout (MDRK) mice, lacking the drug-transporting P-glycoproteins. These transgenic animals are deficient in their blood:brain barrier and accumulate different drugs in brain and other tissues. The MDRK and their wild-type counterparts, ...

journal_title：Environmental toxicology and pharmacology

authors： Sharma RP,Bhandari N,Tsunoda M,Riley RT,Voss KA,Meredith FI

更新日期：2000-03-01 00:00:00

abstract：:A food allergen may be defined as a substance that reacts with IgE antibodies, induces allergic sensitisation or induces allergic reactions. Some allergens only induce allergic sensitisation but do not provoke symptoms, while others bind IgE but do not induce mast cell degranulation. There is no common structure that ...

journal_title：Environmental toxicology and pharmacology

authors： Aalberse RC

更新日期：1997-11-01 00:00:00

abstract：:In utero exposure of neonates to pesticide residues could be damaging to the reproductive tract. Hence, the present study assessed the circulating concentrations of pesticide residues in buffalo and their neonatal calves as well as in the reproductive tract tissue samples of same calves. Also, histopathological altera...

journal_title：Environmental toxicology and pharmacology

authors： Kaur K,Ghuman SS,Singh O,Bedi JS,Gill JP

更新日期：2015-11-01 00:00:00

abstract：:Trichosanthin (TCS) is a type 1 ribosome inactivating protein extracted from Chinese medicinal herb. It possesses various biological functions such as abortifacient, anti-tumor and anti-viral activities. Clinical trial of this compound against human immunodeficiency virus (HIV) had been conducted. However, its use is ...

journal_title：Environmental toxicology and pharmacology

authors： Chan HM,Tam SC

更新日期：2005-07-01 00:00:00

abstract：PURPOSE:Present study aimed at determining blood selenium concentration (Se-B) in a selected population of children inhabiting industrial regions. METHODS:The studies were conducted on a group of 267 children inhabiting industrial regions in Upper Silesia (Poland). Determination of Se-B was performed using hydride gen...

journal_title：Environmental toxicology and pharmacology

authors： Gać P,Pawlas N,Poręba R,Poręba M,Prokopowicz A,Pawlas K

更新日期：2012-09-01 00:00:00

abstract：:The sensitivity of human lymphocytes from different donors to CdCl2 using a complex of methods for determination of cytotoxicity and genotoxicity was studied. As endpoints for cytotoxicity the mitotic index (MI) and apoptosis were evaluated. To indicate genotoxicity chromosome aberrations test (CA) was used. The resul...

journal_title：Environmental toxicology and pharmacology

authors： Gateva S,Jovtchev G,Stergios M

更新日期：2013-07-01 00:00:00

abstract：:Pyrazolo[1,5-a]indole derivatives, a new type of topoisomerase (topo) inhibitor, demonstrate a broad spectrum of antitumor activities. However, the mechanism underlying the induced cytotoxicity remains unclear. In this study, we investigated whether GS-2, one of the derivatives, altered the levels of ROS in breast can...

journal_title：Environmental toxicology and pharmacology

authors： Ji YY,Zhu YM,Wang JW

更新日期：2013-11-01 00:00:00

abstract：:The present armamentarium of commercially available antidotes provides limited protection against the neurological effects of organophosphate exposure. Hence, there is an urgent need to design and develop molecules that can protect and reactivate inhibited-AChE in the central nervous system. Some natural compounds lik...

journal_title：Environmental toxicology and pharmacology

authors： Sharma R,Upadhyaya K,Gupta B,Ghosh KK,Tripathi RP,Musilek K,Kuca K

更新日期：2020-11-01 00:00:00

abstract：:Despite a strong association between cigarette smoking and alarming increase in mortality rate from smoking-related diseases, around 35-40% of the world's population continues to smoke and many more are being exposed to environmental tobacco smoke. Since the role of free radicals and oxidative damage in the pathogenes...

journal_title：Environmental toxicology and pharmacology

authors： Anbarasi K,Sabitha KE,Devi CS

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVES:: To investigate the exposure to terephthalic acid (TPA), and to evaluate it's effects on organ function including the potential risk factors for uroliths and bladder tumor to TPA. METHODS:: Exposure-response modeling was carried out in a cohort of 141 TPA exposure workers and three subgroups were classifie...

journal_title：Environmental toxicology and pharmacology

authors： Dai G,Cui L,Song L,Gong N,Chen J,Zhao R,Wang S,Chang HC,Wang X

更新日期：2005-07-01 00:00:00

abstract：:3-N-Oxalyl-l-2,3-diaminopropanoic acid (β-ODAP) induces neurolathyrism, a motor neuron disease. To elucidate the pathogenic mechanism of this process, the action of β-ODAP on the excitatory amino acid (EAA) receptor-mediated currents was examined using cloned EAA receptors expressed in Xenopus oocytes. On the voltage-...

journal_title：Environmental toxicology and pharmacology

authors： Kusama-Eguchi K,Ikegami F,Kusama T,Lambein F,Watanabe K

更新日期：1996-12-20 00:00:00