New strategies for endovascular recanalization of acute ischemic stroke.

abstract：:Amyotrophic lateral sclerosis can be described as a disease with a poorly understood pathophysiologic mechanism and no treatment that dramatically impacts the course of the disease. Clinical trialists are faced with finding small treatment effects against a background of multiple potential treatments, a past history o...

journal_title：Neurologic clinics

authors： Katz JS,Barohn RJ,Dimachkie MM,Mitsumoto H

更新日期：2015-11-01 00:00:00

abstract：:Aggression is a serious medical problem that can place both the patient and the health care provider at risk. Aggression can result from medical, neurologic, and/or psychiatric disorders. A comprehensive patient evaluation is needed. Treatment options include pharmacotherapy as well as nonpharmacologic interventions, ...

journal_title：Neurologic clinics

authors： Lane SD,Kjome KL,Moeller FG

更新日期：2011-02-01 00:00:00

abstract：:The dysphagia of ALS is characterized by an impaired oral stage of swallowing, which has a direct impact on the seemingly more robust pharyngeal stage. Increased duration of the volitional stage (PPRT) of swallowing, including DT and lingual motility deficits, appear to be the major contributors to the dysphagia. The ...

journal_title：Neurologic clinics

authors： Robbins J

更新日期：1987-05-01 00:00:00

abstract：:Since its clinical introduction in the early 1980s, MRI has transformed the practice of differential diagnosis and disease monitoring for disorders affecting the central nervous system, in particular multiple sclerosis and the allied inflammatory demyelinating diseases. Widespread and dynamic inflammatory processes of...

journal_title：Neurologic clinics

authors： Ali EN,Buckle GJ

更新日期：2009-02-01 00:00:00

abstract：:Impairments of visual perception resulting from brain damage can have serious implications for many aspects of patients' lives, and these impairments should be targeted for intervention. Rehabilitation programs need to be individually tailored to each patient's needs; thus, characterization of a patient's visual perce...

journal_title：Neurologic clinics

authors： Anderson SW

更新日期：2003-08-01 00:00:00

abstract：:Neurologic symptoms are a prominent and often disturbing component of the migraine syndrome in many patients. Collectively termed "aura," migraine-related neurologic symptoms include visual, sensory, language, and motor disturbance. They occur in about one quarter of migraine patients, are classically transient, and a...

journal_title：Neurologic clinics

authors： Foroozan R,Cutrer FM

更新日期：2009-05-01 00:00:00

abstract：:Research models show a strong interrelationship between sleep quality and immune function. The proinflammatory cytokines, interleukin-1, interleukin-6, and tumor necrosis factor α are classified as official sleep-regulatory substances. However, sleep-promoting properties are also possessed by several other immune and ...

journal_title：Neurologic clinics

authors： Gamaldo CE,Shaikh AK,McArthur JC

更新日期：2012-11-01 00:00:00

abstract：:Transcranial Doppler ultrasonography (TCD) is a noninvasive, bedside, portable tool for assessment of cerebral hemodynamics. Modern TCD head frames allow continuous hands-free emboli detection for risk stratification and assessment of treatment efficacy in several cardiovascular diseases. Identifying a focal stenosis,...

journal_title：Neurologic clinics

authors： Hakimi R,Alexandrov AV,Garami Z

更新日期：2020-02-01 00:00:00

abstract：:Nonsurgical, conservative approaches to spine pain include medication and physical therapy. In addition, several invasive procedures have been developed to provide relief when conservative options fail. These include facet joint injection and radiofrequency ablation techniques, translaminar and transforaminal epidural...

journal_title：Neurologic clinics

authors： Levin KH

更新日期：2007-05-01 00:00:00

abstract：:Glycogen is a crucial source of energy in the initial stages of muscle activity and during exercise of high intensity. There are 10 well-defined biochemical defects of glycogen metabolism expressed in muscle and affecting the following enzymes: alpha 1,4 glucosidase (glycogenesis type II), debrancher enzyme (III), bra...

journal_title：Neurologic clinics

authors： Servidei S,DiMauro S

更新日期：1989-02-01 00:00:00

abstract：:Many substances, organic and manufactured, may induce peripheral nerve damage when exposed to them. The expected clinical phenotype is of a distal, sensory or sensorimotor polyneuropathy, often painful, with axonal characteristics on electrodiagnostic and histopathologic analysis. Treatment is limited; often, the only...

journal_title：Neurologic clinics

authors： Grogan PM,Katz JS

更新日期：2005-05-01 00:00:00

abstract：:Sleeping and dreaming always have been a fundamental part of human existence. Most early writing on these subjects was almost entirely speculation. During the twentieth century, however, scientific observation and experimentation abounded. This article emphasizes the evolution of the key concepts and research findings...

journal_title：Neurologic clinics

authors： Dement WC

更新日期：2005-11-01 00:00:00

abstract：:Stroke involving the brainstem and cerebellum frequently presents acute vestibular syndrome. Although vascular vertigo is known to usually accompany other neurologic symptoms and signs, isolated vertigo from small infarcts involving the cerebellum or brainstem has been increasingly recognized. Bedside neuro-otologic e...

journal_title：Neurologic clinics

authors： Lee SH,Kim JS

更新日期：2015-08-01 00:00:00

abstract：:The three states of mammalian being--wakefulness, REM sleep, and NREM sleep--are not mutually exclusive and may occur simultaneously, oscillate rapidly, or appear in dissociated or incomplete form to produce primary sleep parasomnias. Dysfunctions of a wide variety of organ systems may take advantage of the sleeping s...

journal_title：Neurologic clinics

authors： Mahowald MW,Schenck CH

更新日期：1996-11-01 00:00:00

abstract：:MS has certain salient morphologic features that distinguish it from other disorders of white matter and that may represent points of departure for investigation. ...

journal_title：Neurologic clinics

authors： Powell HC,Lampert PW

更新日期：1983-08-01 00:00:00

abstract：:A specific genetic diagnosis can be reached for most children with muscular dystrophy. Advanced diagnostics, including genetic testing and analysis of nonmuscle tissues, such as skin and blood, often allow the diagnosis to be reached using minimally invasive procedures. These diagnostic advances accompany improved und...

journal_title：Neurologic clinics

authors： Mathews KD

更新日期：2003-11-01 00:00:00

abstract：:This article provides a brief overview of the psychiatric syndromes most common in the elderly patient, as well as those most frequently accompanying neurologic disease. Diagnosis, work up, and treatment of depressive, psychotic, and anxiety disorders are also reviewed. This article is directed toward the practicing n...

journal_title：Neurologic clinics

authors： Menza MA,Liberatore BL

更新日期：1998-08-01 00:00:00

abstract：:Despite important advances in the treatment of epilepsy over the past several decades, many patients remain uncontrolled. Partial complex (psychomotor) seizures are the largest problem, with less than two thirds of patients successfully managed despite optimal medication use. In these situations, various surgical proc...

journal_title：Neurologic clinics

authors： Spencer DD,Spencer SS

更新日期：1985-05-01 00:00:00

abstract：:Frontotemporal dementia (FTD) is a unique neurodegenerative disease that can be differentiated from Alzheimer's disease and other diseases that result in cognitive complaints. The primary anatomic focus of degeneration determines the clinical presentation, which can vary from aphasia to behavioral symptoms. Expanding ...

journal_title：Neurologic clinics

authors： Rosen HJ,Lengenfelder J,Miller B

更新日期：2000-11-01 00:00:00

abstract：:Epilepsy affects over one percent of the population, including nearly one million women of childbearing potential. Women with epilepsy represent a particularly challenging group for neurologists and other health care professionals. Affected women are unaware of many of the unique issues they face, including the relati...

journal_title：Neurologic clinics

authors： Foldvary N

更新日期：2001-05-01 00:00:00

abstract：:Neurologists frequently evaluate patients complaining of vision loss, especially when the patient has been examined by an ophthalmologist who has found no ocular disease. A significant proportion of patients presenting to the neurologist with visual complaints have nonorganic or functional visual loss. Although there ...

journal_title：Neurologic clinics

authors： Bruce BB,Newman NJ

更新日期：2010-08-01 00:00:00

abstract：:Myasthenia gravis (MG) is an antibody-mediated muscle disease in which any skeletal muscle can be affected. MG may produce numerous symptoms and signs. To doctors and patients, it may seem like lung disease, stroke, heart disease, or the effects of emotional stress. This article explores the "territory" between MG and...

journal_title：Neurologic clinics

authors： Hopkins LC

更新日期：1994-05-01 00:00:00

abstract：:This review explores the principle features of the immunopathology of multiple sclerosis (MS), particularly relapsing-remitting MS. It highlights the emerging concepts in the pathogenesis of MS in the context of known features of pathology, including the characterization of cytokine networks promoting inflammatory dam...

journal_title：Neurologic clinics

authors： Wu GF,Alvarez E

更新日期：2011-05-01 00:00:00

abstract：:The oldest-old represent the fastest growing segment of society, and the risk of developing dementia continues to increase with advancing age into the 9th and 10th decades of life. The most common form of dementia in the oldest-old is Alzheimer disease (AD), although there are often mixed pathologies contributing to d...

journal_title：Neurologic clinics

authors： Pierce AL,Bullain SS,Kawas CH

更新日期：2017-05-01 00:00:00

abstract：:Myasthenia gravis is an autoimmune disorder characterized by fluctuating weakness of extraocular and proximal limb muscles. It occurs in 1 in 5000 in the overall population and is 2 times more common in women than men. The onset in women is most common in the third decade, and risk of severe exacerbation occurs most f...

journal_title：Neurologic clinics

authors： Waters J

更新日期：2019-02-01 00:00:00

abstract：:Dramatic progress has been made recently in diagnosing and treating herpes simplex virus encephalitis (HSVE). Advances in imaging technology have greatly enhanced our ability to diagnose the illness noninvasively. Acyclovir is of proven efficacy and is generally well-tolerated. The major clinical management problem is...

journal_title：Neurologic clinics

authors： Baringer JR

更新日期：2008-08-01 00:00:00

abstract：:In patients with TIA or ischemic stroke of noncardiac origin antiplatelet drugs are able to decrease the risk of stroke by 11-15%, and the risk of stroke, MI, and vascular death by 15-22%, but not mortality. Low doses of aspirin (50-325 mg) are as effective as high doses and cause less gastrointestinal side effects. S...

journal_title：Neurologic clinics

authors： Diener HC

更新日期：2000-05-01 00:00:00

abstract：:A number of changes have occurred in the management of Parkinson's disease in recent years, with the development of new therapeutic strategies based upon advances in pharmacotherapy and interventional procedures. The treatment of patients with Parkinson's disease is considered here with these advances in mind. Potenti...

journal_title：Neurologic clinics

authors： Aminoff MJ

更新日期：2001-02-01 00:00:00

abstract：:Paraproteinemia frequently is associated with peripheral neuropathy. The clinical manifestations can be protean owing to the potential for multiple organ involvement. A methodical diagnostic approach to patients who have a plasma cell dyscrasia and neuropathy is necessary to ensure the appropriate detection of more wi...

journal_title：Neurologic clinics

authors： Kwan JY

更新日期：2007-02-01 00:00:00

abstract：:As I have indicated in the foregoing discussion, there are several syndromes that with various degrees of proof seem to be caused by unilateral vascular compression of a cranial nerve at the brain stem. Jannetta has summarized this concept as follows: "As we age, our arteries elongate and our brains 'sag'. As a conseq...

journal_title：Neurologic clinics

authors： Wilkins RH

更新日期：1985-05-01 00:00:00