Parkinson's disease.

Abstract:

:A number of changes have occurred in the management of Parkinson's disease in recent years, with the development of new therapeutic strategies based upon advances in pharmacotherapy and interventional procedures. The treatment of patients with Parkinson's disease is considered here with these advances in mind. Potential neuroprotective agents that might slow disease-progression are also considered, but at the present time these agents are more of academic interest than clinical relevance and their role remains to be established. Ablative surgery and stimulation procedures are also helpful in the management of Parkinson's disease, and the utility and limitations of these approaches are briefly summarized.

journal_name

Neurol Clin

journal_title

Neurologic clinics

authors

Aminoff MJ

doi

10.1016/s0733-8619(05)70008-6

subject

Has Abstract

pub_date

2001-02-01 00:00:00

pages

119-28, vi

issue

1

eissn

0733-8619

issn

1557-9875

pii

S0733-8619(05)70008-6

journal_volume

19

pub_type

杂志文章,评审
  • Tourette syndrome. Treatment of tics.

    abstract::There are a number of medications that effectively relieve symptoms in patients with functionally disabling tics. Neuroleptic drugs remain the most predictably effective tic-suppressing agents, but other approaches may be beneficial. This article reviews the spectrum of available therapies to suppress tics and provide...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8619(05)70321-2

    authors: Kurlan R

    更新日期:1997-05-01 00:00:00

  • Cardiogenic syncope. Seizure versus syncope.

    abstract::Our recommendations for the evaluation of the patient with suspected cardiogenic syncope are as follows: An initial thorough history and physical examination of the patient will suggest the diagnosis of cardiogenic syncope in at least 50 per cent of patients. A sudden occurrence of syncope, or "drop attack", is most s...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Dohrmann ML,Cheitlin MD

    更新日期:1986-08-01 00:00:00

  • An introduction to neuroepidemiology.

    abstract::Neuroepidemiology is the application of the methods of epidemiology to the problems of clinical neurology. After diagnosis, the most basic characterization of a disease is its frequency. This characterization requires ascertainment of case (numerator) within their population at risk (denominator) to provide incidence,...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8619(05)70255-3

    authors: Kurtzke JF

    更新日期:1996-05-01 00:00:00

  • Acute Diagnosis and Management of Stroke Presenting Dizziness or Vertigo.

    abstract::Stroke involving the brainstem and cerebellum frequently presents acute vestibular syndrome. Although vascular vertigo is known to usually accompany other neurologic symptoms and signs, isolated vertigo from small infarcts involving the cerebellum or brainstem has been increasingly recognized. Bedside neuro-otologic e...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2015.04.006

    authors: Lee SH,Kim JS

    更新日期:2015-08-01 00:00:00

  • Late-Onset Alzheimer Disease.

    abstract::The oldest-old represent the fastest growing segment of society, and the risk of developing dementia continues to increase with advancing age into the 9th and 10th decades of life. The most common form of dementia in the oldest-old is Alzheimer disease (AD), although there are often mixed pathologies contributing to d...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2017.01.006

    authors: Pierce AL,Bullain SS,Kawas CH

    更新日期:2017-05-01 00:00:00

  • Nervous system infections in patients with cancer.

    abstract::The diagnostic approach to the patient with cancer with suspected CNS infection depends on an analysis of the patient's immune defect, the time course of development of manifestations of infection, and the type of clinical syndrome with supportive evidence for a specific diagnosis coming from laboratory and neuroradio...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8619(02)00075-0

    authors: Pruitt AA

    更新日期:2003-02-01 00:00:00

  • Antidepressant overdose-induced seizures.

    abstract::Antidepressants are the most commonly prescribed class of medications in the United States. The clinician should be mindful of the many antidepressants that can produce seizures following an accidental exposure or an overdose. A broader understanding of the seizure potential of antidepressants, combined with the abili...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2011.05.003

    authors: Judge BS,Rentmeester LL

    更新日期:2011-08-01 00:00:00

  • Tension-type headache.

    abstract::The substantial societal and individual burdens associated with tension-type headache (TTH) constitute a previously overlooked major public health issue. TTH is prevalent, affecting up to 78% of the general population, and 3% suffer from chronic TTH. Pericranial myofascial nociception probably is important for the pat...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2008.11.010

    authors: Bendtsen L,Jensen R

    更新日期:2009-05-01 00:00:00

  • Needle electromyography. Fundamentals, normal and abnormal patterns.

    abstract::The needle electromyographic (EMG) examination is a challenging component of the electrophysiologic study. Knowledge of anatomy and physiology, sound EMG technique, and good patient rapport are required. Every muscle sampled by needle EMG is assessed for insertional activity, spontaneous activity, and voluntary motor-...

    journal_title:Neurologic clinics

    pub_type: 杂志文章

    doi:10.1016/s0733-8619(01)00005-6

    authors: Preston DC,Shapiro BE

    更新日期:2002-05-01 00:00:00

  • Giant cell arteritis.

    abstract::Giant cell arteritis is a systemic vasculitis with a wide clinical spectrum, and it represents a medical emergency. Visual loss is the most feared complication, and when it happens, it tends to be profound and permanent. Prompt diagnosis and treatment are imperative to minimize potentially devastating visual loss and ...

    journal_title:Neurologic clinics

    pub_type: 杂志文章

    doi:10.1016/j.ncl.2010.03.002

    authors: Falardeau J

    更新日期:2010-08-01 00:00:00

  • Acquired peripheral neuropathy.

    abstract::This article reviews the acquired causes of polyneuropathy other than diabetic and acute-onset neuropathies. The author gives a general method to simplify the diagnosis of chronic polyneuropathy. The acquired polyneuropathies are discussed under four main headings: metabolic disorders, toxic or deficiency states, infe...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8619(05)70331-5

    authors: Chalk CH

    更新日期:1997-08-01 00:00:00

  • The nosology of dementia.

    abstract::The nosology of dementia has evolved from the simple distinctions between senility, degenerative dementia, and vascular insults that existed a few decades ago. The differentiation of normal cognitive aging from very mild dementia has sharpened considerably; however, appreciation of the heterogeneity of Alzheimer's dis...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8619(05)70225-5

    authors: Morris JC

    更新日期:2000-11-01 00:00:00

  • Pediatric Brain Tumors.

    abstract::Pediatric central nervous system (CNS) tumors are the most common solid tumors in children and comprise 15% to 20% of all malignancies in children. Presentation, symptoms, and signs depend on tumor location and age of the patient at the time of diagnosis. This article summarizes the common childhood CNS tumors, presen...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2018.04.009

    authors: Udaka YT,Packer RJ

    更新日期:2018-08-01 00:00:00

  • Treatment issues for women with epilepsy.

    abstract::Epilepsy affects over one percent of the population, including nearly one million women of childbearing potential. Women with epilepsy represent a particularly challenging group for neurologists and other health care professionals. Affected women are unaware of many of the unique issues they face, including the relati...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8619(05)70024-4

    authors: Foldvary N

    更新日期:2001-05-01 00:00:00

  • Orbital Disease in Neuro-Ophthalmology.

    abstract::Many abnormalities of the orbit present with neuro-ophthalmic findings, such as impaired ocular motility or alignment, and sensory changes, including optic neuropathy. Comprehensive coverage of all orbital diseases is beyond the scope of this article. This review focuses on diagnosis and management of the most common ...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2016.08.011

    authors: Chang JR,Gruener AM,McCulley TJ

    更新日期:2017-02-01 00:00:00

  • Syncope: Case Studies.

    abstract::Syncope, or the sudden loss of consciousness, is a common presenting symptom for evaluation by neurologists. It is not a unique diagnosis but rather a common manifestation of disorders with diverse mechanisms. Loss of consciousness is typically preceded by a prodrome of symptoms and sometimes there is a clear trigger....

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2016.04.002

    authors: Kleyman I,Weimer LH

    更新日期:2016-08-01 00:00:00

  • The use of somatosensory evoked potentials in the evaluation of the central nervous system.

    abstract::SEPs may be recorded over the spine and scalp to stimulation of any accessible mixed or sensory nerve in the extremities. SEP abnormalities are useful in detecting lesions in central somatosensory pathways. They do not establish a specific diagnosis, but they may suggest or support a diagnosis made on clinical grounds...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Aminoff MJ

    更新日期:1988-11-01 00:00:00

  • Medical management of acute cerebral ischemia.

    abstract::Ischemic stroke is a major cause of death and disability. Despite its high incidence, acute management remains controversial. Most current forms of therapy are designed to reduce complications of a recent stroke or prevent recurrences. Experimental data suggest that the optimal time for intervention is the hour immedi...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Biller J

    更新日期:1992-02-01 00:00:00

  • Toxic myopathies.

    abstract::Toxic myopathies may occur with a variety of prescribed medications, illicit drug abuse, or other toxins. The article discusses an overview of some of the compounds that may cause myopathy, the clinical and laboratory features, histology, mechanisms of action, and potential risk factors of myopathy. The ability to rec...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8619(05)70341-8

    authors: George KK,Pourmand R

    更新日期:1997-08-01 00:00:00

  • Congenital infections.

    abstract::Despite major medical advances, such as the introduction of the rubella vaccine and prolonged postnatal therapy of infants with congenital toxoplasmosis, intrauterine infections remain important causes of deafness, vision loss, and behavioral or neurologic disorders among children worldwide. This article describes the...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8619(02)00014-2

    authors: Bale JF Jr

    更新日期:2002-11-01 00:00:00

  • The natural history of multiple sclerosis.

    abstract::The natural history of MS is highly variable. There is substantial heterogeneity in the clinical manifestations but, at this point, it is reasonable to consider all idiopathic inflammatory demyelinating diseases of the central nervous system as representing a spectrum of the same disease. In large populations, 20% to ...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Weinshenker BG

    更新日期:1995-02-01 00:00:00

  • Medicolegal aspects of iatrogenic injuries.

    abstract::There is often a fine line between medical malpractice and maloccurrance. Physicians need to develop techniques and skills that enhance the patient-physician relationship based on honesty and informed consent. Documentation and proper maintenance of medical records is demanded by the current legal and health care syst...

    journal_title:Neurologic clinics

    pub_type: 杂志文章

    doi:10.1016/s0733-8619(05)70376-5

    authors: Weintraub MI

    更新日期:1998-02-01 00:00:00

  • Practical management of children with apparent learning disabilities.

    abstract::There should be a collaborative evaluation of a child with apparent learning disabilities. This article describes what the neurologist can expect from the other disciplines and how the services can be coordinated, using either the multidisciplinary services of a clinic or comprehensive assessment by a private practiti...

    journal_title:Neurologic clinics

    pub_type: 杂志文章

    doi:

    authors: Schimschock JR,Milford-Cooley M,Cooley N

    更新日期:1984-02-01 00:00:00

  • Viral Encephalitis.

    abstract::Viruses are a frequent cause of encephalitis. Common or important viruses causing encephalitis include herpesviruses, arboviruses, enteroviruses, parechoviruses, mumps, measles, rabies, Ebola, lymphocytic choriomeningitis virus, and henipaviruses. Other viruses may cause an encephalopathy. Host factors and clinical fe...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2018.07.001

    authors: Venkatesan A,Murphy OC

    更新日期:2018-11-01 00:00:00

  • Primary angiitis of the central nervous system: diagnostic criteria.

    abstract::Primary angiitis of the central nervous system (PACNS) is a vasculitis of small arteries and veins of unknown cause restricted to the central nervous system (CNS), and controversy and disagreement exist over the means to establish the diagnosis. Cerebral arteriography, cerebrospinal fluid examination, and MRI singly o...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2014.12.004

    authors: Powers WJ

    更新日期:2015-05-01 00:00:00

  • Intensive Care Unit-Acquired Weakness.

    abstract::Intensive care unit-acquired weakness (ICUAW) is a substantial contributor to long-term disability in survivors of critical illness. Critical illness polyneuropathy, critical illness myopathy, and muscle atrophy from disuse contribute in various proportions to ICUAW. ICUAW is a clinical diagnosis supported by electrop...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2017.06.008

    authors: Kramer CL

    更新日期:2017-11-01 00:00:00

  • Pharmacologic concerns of corticosteroids in the treatment of patients with immune-related neuromuscular diseases.

    abstract::Traditionally, diseases affecting the motor unit had been subdivided based on anatomic criteria into diseases of the anterior horn cell, the peripheral nerve, the neuromuscular junction, and the muscle itself. For therapeutic considerations, however, a more precise cellular and clinicopathologic characterization of th...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Dalakas M

    更新日期:1990-02-01 00:00:00

  • Clinical features of myasthenia gravis.

    abstract::Myasthenia gravis (MG) is an antibody-mediated muscle disease in which any skeletal muscle can be affected. MG may produce numerous symptoms and signs. To doctors and patients, it may seem like lung disease, stroke, heart disease, or the effects of emotional stress. This article explores the "territory" between MG and...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:

    authors: Hopkins LC

    更新日期:1994-05-01 00:00:00

  • Wegener's granulomatosis and ANCA syndromes.

    abstract::The nervous system is involved in approximately 25% of patients with classical Wegener's granulomatosis. The spectrum of this disease has been broadened with the discovery of the anti-neutrophil cytoplasmic antibodies, which are found in diseases sharing many clinical features. The ANCA testing may indicate a common m...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/s0733-8619(05)70353-4

    authors: Jaffe IA

    更新日期:1997-11-01 00:00:00

  • Psychogenic movement disorders.

    abstract::Psychogenic movement disorders (PMDs) can present with varied phenomenology that may resemble organic movement disorders. The diagnosis is based on clinical evaluation with a supporting history and classic features on neurologic examination. Ancillary testing, such as imaging and neurophysiologic studies, can provide ...

    journal_title:Neurologic clinics

    pub_type: 杂志文章,评审

    doi:10.1016/j.ncl.2014.09.013

    authors: Thenganatt MA,Jankovic J

    更新日期:2015-02-01 00:00:00