Toxic myopathies.

abstract：:The last 2 decades represent a period of unparalleled advancement in the understanding of the pathogenesis of Parkinson disease (PD). The discovery of several forms of familial parkinsonism with mendelian inheritance has elucidated insights into the mechanisms underlying the degeneration of dopaminergic neurons of the...

journal_title：Neurologic clinics

authors： Mullin S,Schapira AH

更新日期：2015-02-01 00:00:00

abstract：:Botulinum toxin therapy has emerged as a treatment modality for a variety of spastic- or contracture-related muscle diseases. Its safety has been proven for long-term use in the treatment of benign essential blepharospasm, hemifacial spasm, and certain types of strabismus. Recent approval from the Federal Drug Adminis...

journal_title：Neurologic clinics

authors： Savino PJ,Maus M

更新日期：1991-02-01 00:00:00

abstract：:Addressed are the features of postviral and postvaccinial syndromes affecting the CNS. The relationships among acute disseminated encephalomyelitis, EAE, and MS are discussed. Among the postvaccination syndromes covered are the neurologic sequelae of pertussis immunizations, with a description of a mouse model of this...

journal_title：Neurologic clinics

authors： Sriram S,Steinman L

更新日期：1984-05-01 00:00:00

abstract：:Stroke involving the brainstem and cerebellum frequently presents acute vestibular syndrome. Although vascular vertigo is known to usually accompany other neurologic symptoms and signs, isolated vertigo from small infarcts involving the cerebellum or brainstem has been increasingly recognized. Bedside neuro-otologic e...

journal_title：Neurologic clinics

authors： Lee SH,Kim JS

更新日期：2015-08-01 00:00:00

abstract：:Conventional disease-modifying agents are only moderately effective, so breakthrough disease activity is commonly seen. The evidence from randomized clinical trials and real-world observational data supporting the use of the second-line agents natalizumab, mitoxantrone, and cyclophosphamide are reviewed. Potential fut...

journal_title：Neurologic clinics

authors： Marriott JJ,O'Connor PW

更新日期：2011-05-01 00:00:00

abstract：:Most CNS fungal infections can be divided into those that occur in normal hosts and those that occur in the immunosuppressed host. Cryptococcal infection, however, is common in both groups. The usual clinical presentation of a CNS fungal infection is chronic headache and mental status change. The CSF shows a lymphocyt...

journal_title：Neurologic clinics

authors： Lyons RW,Andriole VT

更新日期：1986-02-01 00:00:00

abstract：:As in most areas of clinical medicine, the history often is the key to determining the diagnosis in patients presenting with neurotologic symptoms. The most common cause of vertigo--benign positional vertigo--can be diagnosed at the bedside based on the characteristic history and the finding of fatigable positional ny...

journal_title：Neurologic clinics

authors： Baloh RW,Jacobson KM

更新日期：1996-02-01 00:00:00

abstract：:Cervicogenic headache is pain referred to the head from a source in the cervical spine or mediated by cervical nerves. Clinical features allow for no more than a diagnosis of probable cervicogenic headache. Definitive diagnosis requires evidence of a cervical source of pain. For most treatments, the evidence is limite...

journal_title：Neurologic clinics

authors： Bogduk N

更新日期：2014-05-01 00:00:00

abstract：:Encephalitis is an acute infection of brain parenchyma characterized clinically by fever, headache, and an altered level of consciousness. There may also be focal or multifocal neurologic deficits, and focal or generalized seizure activity. This article discusses the clinical presentation, diagnosis, and treatment of ...

journal_title：Neurologic clinics

authors： Roos KL

更新日期：1999-11-01 00:00:00

abstract：:Although intravenous thrombolysis with recombinant tissue plasminogen activator is a proven effective therapy for acute ischemic stroke, it is often insufficient to achieve recanalization in patients with large intracranial artery occlusions. In these cases, intra-arterial reperfusion techniques may be useful. Intra-a...

journal_title：Neurologic clinics

authors： Cohen JE,Leker RR,Rabinstein A

更新日期：2013-08-01 00:00:00

abstract：:Prions diseases are uniformly fatal neurodegenerative diseases that occur in sporadic, genetic, and acquired forms. Acquired prion diseases, caused by infectious transmission, are least common. Most prion diseases are not infectious, but occur spontaneously through misfolding of normal prion proteins or genetic mutati...

journal_title：Neurologic clinics

authors： Tee BL,Longoria Ibarrola EM,Geschwind MD

更新日期：2018-11-01 00:00:00

abstract：:A large body of medical and ethical opinion holds that it is justifiable to terminate medical treatment for permanently unconscious persons. But opponents of particular decisions to withhold or withdraw treatment may argue that the decisions violate laws against homicide, pose a threat to the lives of other less sever...

journal_title：Neurologic clinics

authors： Beresford HR

更新日期：1989-11-01 00:00:00

abstract：:Oromandibular disorders are functional disorders and associated pains in the anatomic region of the temporomandibular joint. Their diagnosis and treatment are controversial because of the lack of conformity concerning these disorders among health care providers. This article provides a clear classification of these di...

journal_title：Neurologic clinics

authors： Graff-Radford SB

更新日期：1990-11-01 00:00:00

abstract：:The adverse effects of fetal drug exposures are well documented. Evidence for FAS, impaired intrauterine growth, birth defects, and mental retardation related to alcohol is compelling; evidence for alcohol-induced adverse behaviors and impaired speech is tenuous. Teratogenic, cognitive, or behavioral effects associate...

journal_title：Neurologic clinics

authors： Chiriboga CA

更新日期：1993-08-01 00:00:00

abstract：:The author defines lacunes, classifies types of lacunes and their causes, discusses the correlation between lacunes and specific syndromes, and suggests appropriate therapy. ...

journal_title：Neurologic clinics

authors： Mohr JP

更新日期：1983-02-01 00:00:00

abstract：:The substantial societal and individual burdens associated with tension-type headache (TTH) constitute a previously overlooked major public health issue. TTH is prevalent, affecting up to 78% of the general population, and 3% suffer from chronic TTH. Pericranial myofascial nociception probably is important for the pat...

journal_title：Neurologic clinics

authors： Bendtsen L,Jensen R

更新日期：2009-05-01 00:00:00

abstract：:The etiology of pyogenic infections of the brain and meninges varies principally by age, predisposing causes or conditions, and anatomic site of the infection. An appreciation of these factors, plus the prudent use of noninvasive anatomic diagnostic techniques (such as CT) and examination of the CSF, will provide a ba...

journal_title：Neurologic clinics

authors： Overturf GD

更新日期：1986-02-01 00:00:00

abstract：:Personal experience indicates we sleep differently when sick. Data reviewed demonstrate the extent to which sleep is altered during the course of infection of host organisms by several classes of pathogens. One important unanswered question is whether or not the alterations in sleep during infection are of functional ...

journal_title：Neurologic clinics

authors： Opp MR

更新日期：2006-08-01 00:00:00

abstract：:Different types of conduction defects, avenues available for functional recovery after demyelination, therapeutic and diagnostic measures, and electrophysiologic testing are covered. ...

journal_title：Neurologic clinics

authors： Eisen A

更新日期：1983-08-01 00:00:00

abstract：:The fourth edition of The Diagnostic and Statistical Manual of Mental Disorders defines delirium as "a reversible state of confusion with a reduced level of consciousness manifest as an inability to focus, sustain or shift attention." Pharmacologic agents are important contributors to delirium in hospitalized elderly ...

journal_title：Neurologic clinics

authors： Hanson MR,Gálvez-Jiménez N

更新日期：2004-05-01 00:00:00

abstract：:Paraproteinemia frequently is associated with peripheral neuropathy. The clinical manifestations can be protean owing to the potential for multiple organ involvement. A methodical diagnostic approach to patients who have a plasma cell dyscrasia and neuropathy is necessary to ensure the appropriate detection of more wi...

journal_title：Neurologic clinics

authors： Kwan JY

更新日期：2007-02-01 00:00:00

abstract：:The neurologic manifestations of gastrointestinal disease are generally thought to be uncommon, although an increasing number of previously unidentified associations are being established. These neurologic disorders may result from nutritional or non-nutritional causes. In the absence of clear malnutrition, it is like...

journal_title：Neurologic clinics

authors： Albers JW,Nostrant TT,Riggs JE

更新日期：1989-08-01 00:00:00

abstract：:Through the use of IHS criteria, large population-based epidemiologic studies in Denmark, the United States, France, Canada, and elsewhere have shed light on the descriptive epidemiology of migraine. Although migraine is a remarkably common cause of temporary disability, many migraineurs, even those with disabling hea...

journal_title：Neurologic clinics

authors： Silberstein SD,Lipton RB

更新日期：1996-05-01 00:00:00

abstract：:Dramatic progress has been made recently in diagnosing and treating herpes simplex virus encephalitis (HSVE). Advances in imaging technology have greatly enhanced our ability to diagnose the illness noninvasively. Acyclovir is of proven efficacy and is generally well-tolerated. The major clinical management problem is...

journal_title：Neurologic clinics

authors： Baringer JR

更新日期：2008-08-01 00:00:00

abstract：:Traumatic injury to the posterior fossa is a complex pathologic condition because of the great heterogeneity of lesions present. Treatment of primary brain injuries and prevention of secondary brain injuries is the mainstay of management. It is imperative to recognize traumatic lesions of the posterior fossa early bec...

journal_title：Neurologic clinics

authors： Nixon M,Ambekar S,Zhang S,Markham C,Akbarian-Tefaghi H,Morrow K,Nanda A,Guthikonda B

更新日期：2014-11-01 00:00:00

abstract：:This article provides a brief overview of the psychiatric syndromes most common in the elderly patient, as well as those most frequently accompanying neurologic disease. Diagnosis, work up, and treatment of depressive, psychotic, and anxiety disorders are also reviewed. This article is directed toward the practicing n...

journal_title：Neurologic clinics

authors： Menza MA,Liberatore BL

更新日期：1998-08-01 00:00:00

abstract：:The authors divide biological toxins into animal, plant, and bacterial classes and discuss each within a context of demographic, clinical and research examples. Advances in our knowledge are highlighted, and the authors relate the implications of this knowledge to target-specific neurologic involvement. ...

journal_title：Neurologic clinics

authors： Goetz CG,Meisel E

更新日期：2000-08-01 00:00:00

abstract：:Many abnormalities of the orbit present with neuro-ophthalmic findings, such as impaired ocular motility or alignment, and sensory changes, including optic neuropathy. Comprehensive coverage of all orbital diseases is beyond the scope of this article. This review focuses on diagnosis and management of the most common ...

journal_title：Neurologic clinics

authors： Chang JR,Gruener AM,McCulley TJ

更新日期：2017-02-01 00:00:00

abstract：:Nonsurgical, conservative approaches to spine pain include medication and physical therapy. In addition, several invasive procedures have been developed to provide relief when conservative options fail. These include facet joint injection and radiofrequency ablation techniques, translaminar and transforaminal epidural...

journal_title：Neurologic clinics

authors： Levin KH

更新日期：2007-05-01 00:00:00

abstract：:Shift work and its negative consequences are becoming more relevant as the economy becomes increasing globalized. For many individuals, shift work serves as a significant biological and psychosocial challenge leading to Shift Work Disorder (SWD). Beyond the symptoms of sleep and excessive sleepiness, the range of cons...

journal_title：Neurologic clinics

authors： Cheng P,Drake C

更新日期：2019-08-01 00:00:00