Prion Diseases.

abstract：:The presence of a monoclonal protein in the serum of a patient with peripheral neuropathy raises the suspicion of systemic amyloidosis, POEMS syndrome, macroglobulinemia, multiple myeloma, or lymphoma. If these conditions are excluded, the patient is classified as having a monoclonal gammopathy of undetermined signifi...

journal_title：Neurologic clinics

authors： Kyle RA

更新日期：1992-08-01 00:00:00

abstract：:In the current era of escalating globalization with rapid transport, changing climate, and an ever growing human population with associated changes in lifestyle, poverty, and war, the emergence of new neurologic infections is accelerated. Understanding their origins using epidemiologic and molecular tools will contrib...

journal_title：Neurologic clinics

authors： Johnson RT,Power C

更新日期：2008-08-01 00:00:00

abstract：:This article discusses antibodies associated with immune-mediated myasthenia gravis and the pathologic action of these antibodies at the neuromuscular junctions of skeletal muscle. To explain how these antibodies act, we consider the physiology of neuromuscular transmission with emphasis on 4 features: the structure o...

journal_title：Neurologic clinics

authors： Ruff RL,Lisak RP

更新日期：2018-05-01 00:00:00

abstract：:Myoclonus is defined as sudden, brief, shock-like, involuntary movements caused by muscular contractions or inhibitions. Etiologic classification organizes the myoclonus disorders and provides major categories of clinical presentation. However, classifying myoclonus according to its source provides insight about its p...

journal_title：Neurologic clinics

authors： Caviness JN

更新日期：2009-08-01 00:00:00

abstract：:Conventional disease-modifying agents are only moderately effective, so breakthrough disease activity is commonly seen. The evidence from randomized clinical trials and real-world observational data supporting the use of the second-line agents natalizumab, mitoxantrone, and cyclophosphamide are reviewed. Potential fut...

journal_title：Neurologic clinics

authors： Marriott JJ,O'Connor PW

更新日期：2011-05-01 00:00:00

abstract：:Electronystagmography in 1990 should identify a vestibular abnormality with which to associate the clinical symptoms. The vestibular test battery method and interpretation reveals its application in neurotologic diagnosis. ...

journal_title：Neurologic clinics

authors： Brookler KH

更新日期：1990-05-01 00:00:00

abstract：:Echocardiography is an established technology encompassing an increasingly wide variety of clinical situations including cardioembolism and the detection of CAD in patients with cerebral ischemia and in patients undergoing neurovascular surgery. Echocardiography will continue to occupy a pivotal role in clinical manag...

journal_title：Neurologic clinics

authors： Tegeler CH,Kitzman DW

更新日期：1993-05-01 00:00:00

abstract：:Impairments of visual perception resulting from brain damage can have serious implications for many aspects of patients' lives, and these impairments should be targeted for intervention. Rehabilitation programs need to be individually tailored to each patient's needs; thus, characterization of a patient's visual perce...

journal_title：Neurologic clinics

authors： Anderson SW

更新日期：2003-08-01 00:00:00

abstract：:This article concentrates primarily on infections of viral origin, although numerous microorganisms can infect the fetal and newborn brain (see Tables 1 and 2). Intrauterine infections occur most often for HIV, CMV and rubella, whereas HSV is preferentially transmitted intrapartum. In the last decade, changes in the e...

journal_title：Neurologic clinics

authors： Griffith BP,Booss J

更新日期：1994-08-01 00:00:00

abstract：:Focal, small-to-moderate and transient improvement occurred in the muscle strength and function of patients with ALS who received TRH in dose-response and screening studies. In a small pilot study of 12 patients, 3 months administration of TRH at 10 mg per kg on alternate days resulted in localized increased strength ...

journal_title：Neurologic clinics

authors： Brooks BR,Sufit RL,Montgomery GK,Beaulieu DA,Erickson LM

更新日期：1987-02-01 00:00:00

abstract：:Reflex sympathetic dystrophy (RSD) and causalgia appear to reflect identical pictures even though the latter is related to nerve injury and the former is not. Overriding past and present skepticism about a role for the sympathetic system in their cause and treatment, the International Association for the Study of Pain...

journal_title：Neurologic clinics

authors： Ochoa JL,Verdugo RJ

更新日期：1995-05-01 00:00:00

abstract：:Nerve agents cause a rapidly fatal cholinergic crisis, but rapid, appropriate antidotal treatment saves lives. Survivors of nerve-agent poisoning generally are healthy, unlike survivors of some other chemical agent attacks. Neurologists can assist first responders and mass casualty planners materially by serving as re...

journal_title：Neurologic clinics

authors： Newmark J

更新日期：2005-05-01 00:00:00

abstract：:"Myasthenia gravis (MG) is the most common autoimmune neuromuscular disorder. This article highlights several cases that the practicing neurologist may encounter in the treatment of MG. Diagnostic uncertainty continues to be an issue in patients who are seronegative to the 2 most common antibodies, acetylcholine recep...

journal_title：Neurologic clinics

authors： Nguyen T,Phan CL,Supsupin E Jr,Sheikh K

更新日期：2020-08-01 00:00:00

abstract：:Different types of conduction defects, avenues available for functional recovery after demyelination, therapeutic and diagnostic measures, and electrophysiologic testing are covered. ...

journal_title：Neurologic clinics

authors： Eisen A

更新日期：1983-08-01 00:00:00

abstract：:Progressive muscular atrophy (PMA) is a rare, sporadic, adult-onset motor neuron disease, clinically characterized by isolated lower motor neuron features; however, clinically evident upper motor neuron signs may emerge in some patients. Subclinical upper motor neuron involvement is identified pathologically, radiolog...

journal_title：Neurologic clinics

authors： Liewluck T,Saperstein DS

更新日期：2015-11-01 00:00:00

abstract：:Overall, the majority of patients with optic pathway tumors will have stable disease regardless if they are radiated or receive chemotherapy. This is a very indolent tumor system and, for the most part, not a threat to life. Because of this, issues regarding appropriate therapeutic approaches have yet to be resolved. ...

journal_title：Neurologic clinics

authors： Cohen ME,Duffner PK

更新日期：1991-05-01 00:00:00

abstract：:Considerable evidence exists of hypothalamic dysfunction in patients with anorexia nervosa and bulimia nervosa. This dysfunction is reflected in disturbances of endocrine function including abnormalities of gonadotropin, growth hormone, and corticotropin-releasing hormone secretion. Whereas these disturbances are gene...

journal_title：Neurologic clinics

authors： Newman MM,Halmi KA

更新日期：1988-02-01 00:00:00

abstract：:The author discusses the noninvasive tests and their roles relative to intravenous digital subtraction angiography in the assessment of patients with carotid disease. ...

journal_title：Neurologic clinics

authors： Ackerman RH

更新日期：1983-02-01 00:00:00

abstract：:Sleeping and dreaming always have been a fundamental part of human existence. Most early writing on these subjects was almost entirely speculation. During the twentieth century, however, scientific observation and experimentation abounded. This article emphasizes the evolution of the key concepts and research findings...

journal_title：Neurologic clinics

authors： Dement WC

更新日期：2005-11-01 00:00:00

abstract：:Nerve conduction studies and needle electromyography provide important and complementary information as part of an electrodiagnostic study. Potential technical problems that are encountered during the studies may interfere with accurate and reliable acquisition of information and interpretation of the data. Recognitio...

journal_title：Neurologic clinics

authors： Rubin DI

更新日期：2012-05-01 00:00:00

abstract：:Throughout pregnancy and the puerperium, a variety of hormonal and physiologic changes occur that are associated with pregnancy-specific neurologic conditions, which may also influence known preexisting medical conditions or bring previously unknown neurologic conditions to clinical attention. This article reviews the...

journal_title：Neurologic clinics

authors： Delfyett WT,Fetzer DT

更新日期：2012-08-01 00:00:00

abstract：:Cerebellar ataxia can be caused by a variety of disorders, including degenerative processes, autoimmune and paraneoplastic illness as well as by gene mutations inherited in autosomal dominant, autosomal recessive, or X-linked fashions. In this review, we highlight the treatments for cerebellar ataxia in a systematic w...

journal_title：Neurologic clinics

authors： Kwei KT,Kuo SH

更新日期：2020-05-01 00:00:00

abstract：:Neuroepidemiology is the application of the methods of epidemiology to the problems of clinical neurology. After diagnosis, the most basic characterization of a disease is its frequency. This characterization requires ascertainment of case (numerator) within their population at risk (denominator) to provide incidence,...

journal_title：Neurologic clinics

authors： Kurtzke JF

更新日期：1996-05-01 00:00:00

abstract：:Eclampsia continues to be a significant cause of maternal and fetal death throughout the world. Neurologists have a specific role to play in the diagnosis and management of patients who have eclampsia, especially those who have recurrent seizures, raised intracranial pressure, and coma. Postpartum patients may be admi...

journal_title：Neurologic clinics

authors： Kaplan PW

更新日期：2004-11-01 00:00:00

abstract：:The past 40 years have seen the evolution of acute ischemic stroke management from unproven therapies du jour, such as steroids, heparin for stroke in evolution, and hypervolemic-hemodilution, to more of a scientific basis for our decision-making process. This evolution is directly related to the advancements in imagi...

journal_title：Neurologic clinics

authors： Kelley RE,Martin-Schild S

更新日期：2012-02-01 00:00:00

abstract：:The epidemiology of vasculitis has witnessed extraordinary advances in the past decade influenced by the worldwide increased recognition and accurate classification and diagnosis of the vasculitides, and insights brought by genome-wide association studies and other genetic investigations that contribute to the underst...

journal_title：Neurologic clinics

authors： Younger DS

更新日期：2016-11-01 00:00:00

abstract：:Classifications and definitions are essential to facilitate communication; promote accurate diagnostic criteria; develop, test, and use effective therapies; and specify knowledge gaps. This article describes the development of the International Classification of Vestibular Disorders (ICVD) initiative. It describes its...

journal_title：Neurologic clinics

authors： Bisdorff AR,Staab JP,Newman-Toker DE

更新日期：2015-08-01 00:00:00

abstract：:Vasculitis or angiitis refers to a group of inflammatory disorders of the blood vessels that cause structural damage to the affected vessel, including thickening and weakening of the vessel wall, narrowing of its lumen, and, usually, vascular necrosis. Systemic vasculitis is classified according to the vessel size and...

journal_title：Neurologic clinics

authors： Minagar A,Fowler M,Harris MK,Jaffe SL

更新日期：2010-02-01 00:00:00

abstract：:Neoplastic meningitis appears to be increasing in frequency with improvements in the treatment of many cancers. It is most often recognized in patients with leukemia, breast cancer, lymphomas, and small-cell cancer of the lung, although it may be seen with virtually any malignancy. Treatment should include intrathecal...

journal_title：Neurologic clinics

authors： Grossman SA,Moynihan TJ

更新日期：1991-11-01 00:00:00

abstract：:Chorea (Greek for "dance") refers to irregular, rapid, flowing, non-stereotyped and random involuntary movements that often possess a writhing quality, referred to as choreoathetosis. When mild, it may be difficult to differentiate from restlessness. The movements can be strikingly asymmetric, as in hemichorea, or gen...

journal_title：Neurologic clinics

authors： Higgins DS Jr

更新日期：2001-08-01 00:00:00