Noninvasive diagnosis of carotid disease in the era of digital subtraction angiography.

abstract：:Childhood sleep-wake disorders are common and associated with significant impairment of quality of life. The recent discovery of hypocretin deficiency as the pathophysiologic basis for narcolepsy-cataplexy is likely to spur the development of hypocretin analogs for definitive treatment [82,83]. The link between disrup...

journal_title：Neurologic clinics

authors： Kotagal S

更新日期：2003-11-01 00:00:00

abstract：:The autosomal dominant spinocerebellar ataxias are a diverse and clinically heterogeneous group of disorders characterized by degeneration and dysfunction of the cerebellum and its associated pathways. Clinical and diagnostic evaluation can be challenging because of phenotypic overlap among causes, and a stratified an...

journal_title：Neurologic clinics

authors： Shakkottai VG,Fogel BL

更新日期：2013-11-01 00:00:00

abstract：:Ischemic stroke is a major cause of death and disability. Despite its high incidence, acute management remains controversial. Most current forms of therapy are designed to reduce complications of a recent stroke or prevent recurrences. Experimental data suggest that the optimal time for intervention is the hour immedi...

journal_title：Neurologic clinics

authors： Biller J

更新日期：1992-02-01 00:00:00

abstract：:This article reviews the acquired causes of polyneuropathy other than diabetic and acute-onset neuropathies. The author gives a general method to simplify the diagnosis of chronic polyneuropathy. The acquired polyneuropathies are discussed under four main headings: metabolic disorders, toxic or deficiency states, infe...

journal_title：Neurologic clinics

authors： Chalk CH

更新日期：1997-08-01 00:00:00

abstract：:The fourth edition of The Diagnostic and Statistical Manual of Mental Disorders defines delirium as "a reversible state of confusion with a reduced level of consciousness manifest as an inability to focus, sustain or shift attention." Pharmacologic agents are important contributors to delirium in hospitalized elderly ...

journal_title：Neurologic clinics

authors： Hanson MR,Gálvez-Jiménez N

更新日期：2004-05-01 00:00:00

abstract：:The immune system plays a significant role in Alzheimer disease (AD). β-Amyloid deposition in the cortex is thought to be an initiating event in AD and the widely believed amyloid hypothesis proposes removal of amyloid may delay disease progression. Human trials of active or passive immune agents have failed to show b...

journal_title：Neurologic clinics

authors： Farlow MR,Brosch JR

更新日期：2013-08-01 00:00:00

abstract：:Most patients who have endured a stroke sustain behavioral changes, although in many instances these effects can be subtle. Although behavioral changes after a stroke tend to improve, they may persist and have serious effects on daily living activities. This article reviews the more familiar behavioral changes that fo...

journal_title：Neurologic clinics

authors： Mark VW

更新日期：2016-02-01 00:00:00

abstract：:Most CNS fungal infections can be divided into those that occur in normal hosts and those that occur in the immunosuppressed host. Cryptococcal infection, however, is common in both groups. The usual clinical presentation of a CNS fungal infection is chronic headache and mental status change. The CSF shows a lymphocyt...

journal_title：Neurologic clinics

authors： Lyons RW,Andriole VT

更新日期：1986-02-01 00:00:00

abstract：:Neurologists frequently evaluate patients complaining of vision loss, especially when the patient has been examined by an ophthalmologist who has found no ocular disease. A significant proportion of patients presenting to the neurologist with visual complaints have nonorganic or functional visual loss. Although there ...

journal_title：Neurologic clinics

authors： Bruce BB,Newman NJ

更新日期：2010-08-01 00:00:00

abstract：:Legal issues must be considered in caring for patients with epilepsy. Doctors caring for people with epilepsy may be legally involved in three primary ways: as the agent of social control, as patient advocate, and as the target of liability or malpractice suits. This article examines these factors and the implications...

journal_title：Neurologic clinics

authors： Hughes JT,Devinsky O

更新日期：1994-02-01 00:00:00

abstract：:Normal cell replication is regulated by growth factors such as epidermal growth factor (EGF) and platelet-derived growth factor (PDGF) that act through binding to specific surface receptors on target cells. Oncogenes may exert their transforming activity by encoding proteins that mimic the function of the normal regul...

journal_title：Neurologic clinics

authors： Westermark B,Nister M,Heldin CH

更新日期：1985-11-01 00:00:00

abstract：:Giant cell arteritis is a systemic vasculitis with a wide clinical spectrum, and it represents a medical emergency. Visual loss is the most feared complication, and when it happens, it tends to be profound and permanent. Prompt diagnosis and treatment are imperative to minimize potentially devastating visual loss and ...

journal_title：Neurologic clinics

authors： Falardeau J

更新日期：2010-08-01 00:00:00

abstract：:Motor fluctuations and dyskinesias are common motor complications that manifest within the first few years from the initiation of therapy in patients with Parkinson disease. These complications negatively affect the quality of life and represent an important source of disability. A growing number of therapeutic option...

journal_title：Neurologic clinics

authors： Espay AJ

更新日期：2010-11-01 00:00:00

abstract：:Frontotemporal dementia (FTD) is a unique neurodegenerative disease that can be differentiated from Alzheimer's disease and other diseases that result in cognitive complaints. The primary anatomic focus of degeneration determines the clinical presentation, which can vary from aphasia to behavioral symptoms. Expanding ...

journal_title：Neurologic clinics

authors： Rosen HJ,Lengenfelder J,Miller B

更新日期：2000-11-01 00:00:00

abstract：:The authors review iatrogenic complications of stereotactic surgery, including tumor biopsy, cyst or abscess aspiration, movement disorder surgery, and radiosurgery. The expected morbidities and steps taken to reduce complications are also discussed. ...

journal_title：Neurologic clinics

authors： Kondziolka D,Firlik AD,Lunsford LD

更新日期：1998-02-01 00:00:00

abstract：:The term thoracic outlet syndromes, is a group designation for several distinct disorders (one of questionable validity) involving various components of the brachial plexus, the blood vessels, or both, at various points between the base of the neck and the axilla. Four of the five subgroups (true neurologic TOS, arter...

journal_title：Neurologic clinics

authors： Wilbourn AJ

更新日期：1999-08-01 00:00:00

abstract：:The last 2 decades represent a period of unparalleled advancement in the understanding of the pathogenesis of Parkinson disease (PD). The discovery of several forms of familial parkinsonism with mendelian inheritance has elucidated insights into the mechanisms underlying the degeneration of dopaminergic neurons of the...

journal_title：Neurologic clinics

authors： Mullin S,Schapira AH

更新日期：2015-02-01 00:00:00

abstract：:This article provides a brief overview of the psychiatric syndromes most common in the elderly patient, as well as those most frequently accompanying neurologic disease. Diagnosis, work up, and treatment of depressive, psychotic, and anxiety disorders are also reviewed. This article is directed toward the practicing n...

journal_title：Neurologic clinics

authors： Menza MA,Liberatore BL

更新日期：1998-08-01 00:00:00

abstract：:Sleeping and dreaming always have been a fundamental part of human existence. Most early writing on these subjects was almost entirely speculation. During the twentieth century, however, scientific observation and experimentation abounded. This article emphasizes the evolution of the key concepts and research findings...

journal_title：Neurologic clinics

authors： Dement WC

更新日期：2005-11-01 00:00:00

abstract：:Aggression is a serious medical problem that can place both the patient and the health care provider at risk. Aggression can result from medical, neurologic, and/or psychiatric disorders. A comprehensive patient evaluation is needed. Treatment options include pharmacotherapy as well as nonpharmacologic interventions, ...

journal_title：Neurologic clinics

authors： Lane SD,Kjome KL,Moeller FG

更新日期：2011-02-01 00:00:00

abstract：:The authors highlight the potential importance of neuropeptides as clinical tools in the study and treatment of pain. Although many questions remain unanswered, it is encouraging that several clinical and experimental advances have shed new light on the neuropharmacology of nociception and have prompted new hope for m...

journal_title：Neurologic clinics

authors： Recht LD,Abrams GM

更新日期：1986-11-01 00:00:00

abstract：:The etiology of pyogenic infections of the brain and meninges varies principally by age, predisposing causes or conditions, and anatomic site of the infection. An appreciation of these factors, plus the prudent use of noninvasive anatomic diagnostic techniques (such as CT) and examination of the CSF, will provide a ba...

journal_title：Neurologic clinics

authors： Overturf GD

更新日期：1986-02-01 00:00:00

abstract：:Viruses are a frequent cause of encephalitis. Common or important viruses causing encephalitis include herpesviruses, arboviruses, enteroviruses, parechoviruses, mumps, measles, rabies, Ebola, lymphocytic choriomeningitis virus, and henipaviruses. Other viruses may cause an encephalopathy. Host factors and clinical fe...

journal_title：Neurologic clinics

authors： Venkatesan A,Murphy OC

更新日期：2018-11-01 00:00:00

abstract：:Meaningful symptom management can have a profound impact on quality of life. It can challenge time parameters during clinic, and therefore thought should be given to strategies that can improve efficiency and thereby make the undertaking more tenable. For any given symptom, the building blocks of care, such as vitamin...

journal_title：Neurologic clinics

authors： Crabtree-Hartman E

更新日期：2018-02-01 00:00:00

abstract：:Tuberous sclerosis is a multisystem disorder characterized by changes primarily involving the skin, eye, and central nervous system. Although the disease often produces mental retardation and seizures, this is not universal, and some patients with tuberous sclerosis lead a relatively normal life. ...

journal_title：Neurologic clinics

authors： Hanno R,Beck R

更新日期：1987-08-01 00:00:00

abstract：:Although intravenous thrombolysis with recombinant tissue plasminogen activator is a proven effective therapy for acute ischemic stroke, it is often insufficient to achieve recanalization in patients with large intracranial artery occlusions. In these cases, intra-arterial reperfusion techniques may be useful. Intra-a...

journal_title：Neurologic clinics

authors： Cohen JE,Leker RR,Rabinstein A

更新日期：2013-08-01 00:00:00

abstract：:Syncope, or the sudden loss of consciousness, is a common presenting symptom for evaluation by neurologists. It is not a unique diagnosis but rather a common manifestation of disorders with diverse mechanisms. Loss of consciousness is typically preceded by a prodrome of symptoms and sometimes there is a clear trigger....

journal_title：Neurologic clinics

authors： Kleyman I,Weimer LH

更新日期：2016-08-01 00:00:00

abstract：:In summary, PET and SPECT are versatile imaging modalities capable of providing dynamic information regarding the metabolism and physiology of brain and brain tumor. PET and SPECT are useful adjuncts to MRI and CT scanning in the important clinical areas of presurgical estimations of tumor grade. In addition, PET can ...

journal_title：Neurologic clinics

authors： Rozental JM

更新日期：1991-05-01 00:00:00

abstract：:Psychogenic movement disorders (PMDs) can present with varied phenomenology that may resemble organic movement disorders. The diagnosis is based on clinical evaluation with a supporting history and classic features on neurologic examination. Ancillary testing, such as imaging and neurophysiologic studies, can provide ...

journal_title：Neurologic clinics

authors： Thenganatt MA,Jankovic J

更新日期：2015-02-01 00:00:00

abstract：:Face recognition is one of the most complex visual tasks performed by the human brain. Data from monkeys suggest that area IT may play a key role in identifying faces, and functional imaging research suggests that the human homologue of IT may be located in the medial occipitotemporal cortex, where a FFA has been loca...

journal_title：Neurologic clinics

authors： Barton JJ

更新日期：2003-05-01 00:00:00