Frontotemporal dementia.

abstract：:This article discusses antibodies associated with immune-mediated myasthenia gravis and the pathologic action of these antibodies at the neuromuscular junctions of skeletal muscle. To explain how these antibodies act, we consider the physiology of neuromuscular transmission with emphasis on 4 features: the structure o...

journal_title：Neurologic clinics

authors： Ruff RL,Lisak RP

更新日期：2018-05-01 00:00:00

abstract：:Personal experience indicates we sleep differently when sick. Data reviewed demonstrate the extent to which sleep is altered during the course of infection of host organisms by several classes of pathogens. One important unanswered question is whether or not the alterations in sleep during infection are of functional ...

journal_title：Neurologic clinics

authors： Opp MR

更新日期：2006-08-01 00:00:00

abstract：:Paraproteinemia frequently is associated with peripheral neuropathy. The clinical manifestations can be protean owing to the potential for multiple organ involvement. A methodical diagnostic approach to patients who have a plasma cell dyscrasia and neuropathy is necessary to ensure the appropriate detection of more wi...

journal_title：Neurologic clinics

authors： Kwan JY

更新日期：2007-02-01 00:00:00

abstract：:The fourth edition of The Diagnostic and Statistical Manual of Mental Disorders defines delirium as "a reversible state of confusion with a reduced level of consciousness manifest as an inability to focus, sustain or shift attention." Pharmacologic agents are important contributors to delirium in hospitalized elderly ...

journal_title：Neurologic clinics

authors： Hanson MR,Gálvez-Jiménez N

更新日期：2004-05-01 00:00:00

abstract：:Metabolic and mitochondrial myopathies encompass a heterogeneous group of disorders that result in impaired energy production in skeletal muscle. Symptoms of premature muscle fatigue, sometimes leading to myalgia, rhabdomyolysis, and myoglobinuria, typically occur with exercise that would normally depend on the defect...

journal_title：Neurologic clinics

authors： Sharp LJ,Haller RG

更新日期：2014-08-01 00:00:00

abstract：:MS has certain salient morphologic features that distinguish it from other disorders of white matter and that may represent points of departure for investigation. ...

journal_title：Neurologic clinics

authors： Powell HC,Lampert PW

更新日期：1983-08-01 00:00:00

abstract：:Tuberous sclerosis is a multisystem disorder characterized by changes primarily involving the skin, eye, and central nervous system. Although the disease often produces mental retardation and seizures, this is not universal, and some patients with tuberous sclerosis lead a relatively normal life. ...

journal_title：Neurologic clinics

authors： Hanno R,Beck R

更新日期：1987-08-01 00:00:00

abstract：:There should be a collaborative evaluation of a child with apparent learning disabilities. This article describes what the neurologist can expect from the other disciplines and how the services can be coordinated, using either the multidisciplinary services of a clinic or comprehensive assessment by a private practiti...

journal_title：Neurologic clinics

authors： Schimschock JR,Milford-Cooley M,Cooley N

更新日期：1984-02-01 00:00:00

abstract：:Prions diseases are uniformly fatal neurodegenerative diseases that occur in sporadic, genetic, and acquired forms. Acquired prion diseases, caused by infectious transmission, are least common. Most prion diseases are not infectious, but occur spontaneously through misfolding of normal prion proteins or genetic mutati...

journal_title：Neurologic clinics

authors： Tee BL,Longoria Ibarrola EM,Geschwind MD

更新日期：2018-11-01 00:00:00

abstract：:A recently described syndrome, disabling positional vertigo (DPV), is characterized by persistent and progressive vertigo that is always associated with nausea and occasionally with vomiting; symptoms are made worse with changes in head position and are lessened with bedrest. Patients with DPV have abnormal results on...

journal_title：Neurologic clinics

authors： Møller MB,Møller AR

更新日期：1990-05-01 00:00:00

abstract：:Parasomnias are classified into nonrapid eye movement and rapid eye movement sleep parasomnias. It is important for the clinician to consider other parasomnia mimics that present to the sleep disorders clinic. These conditions can be differentiated by taking a detailed sleep history and conducting nocturnal polysomnog...

journal_title：Neurologic clinics

authors： Malhotra RK,Avidan AY

更新日期：2012-11-01 00:00:00

abstract：:Shift work and its negative consequences are becoming more relevant as the economy becomes increasing globalized. For many individuals, shift work serves as a significant biological and psychosocial challenge leading to Shift Work Disorder (SWD). Beyond the symptoms of sleep and excessive sleepiness, the range of cons...

journal_title：Neurologic clinics

authors： Cheng P,Drake C

更新日期：2019-08-01 00:00:00

abstract：:This article defines the evolving role of the neurologist as a provider of palliative care. As neurologists care for chronically and critically ill, dying patients, and individuals whose diseases are incurable at the time of diagnosis, clinical competence requires expertise in the principles and practice of palliative...

journal_title：Neurologic clinics

authors： Foley KM,Carver AC

更新日期：2001-11-01 00:00:00

abstract：:The immune system plays a significant role in Alzheimer disease (AD). β-Amyloid deposition in the cortex is thought to be an initiating event in AD and the widely believed amyloid hypothesis proposes removal of amyloid may delay disease progression. Human trials of active or passive immune agents have failed to show b...

journal_title：Neurologic clinics

authors： Farlow MR,Brosch JR

更新日期：2013-08-01 00:00:00

abstract：:The reasonable clinical approach to the patient who has low back pain includes a search for any of the red flags that would prompt consideration of additional diagnostic testing for serious underlying disease. The common patterns of back pain would be explored in an effort to categorize the patient's symptoms and to b...

journal_title：Neurologic clinics

authors： Swenson R

更新日期：1999-02-01 00:00:00

abstract：:This article concentrates primarily on infections of viral origin, although numerous microorganisms can infect the fetal and newborn brain (see Tables 1 and 2). Intrauterine infections occur most often for HIV, CMV and rubella, whereas HSV is preferentially transmitted intrapartum. In the last decade, changes in the e...

journal_title：Neurologic clinics

authors： Griffith BP,Booss J

更新日期：1994-08-01 00:00:00

abstract：:Selecting appropriate laboratory tests in diagnosing peripheral neuropathies is important because it increases the yield of correct diagnoses and is cost effective. A large number of tests are available. This article provides a guide to selecting appropriate tests and reviews the clinical situations that suggest speci...

journal_title：Neurologic clinics

authors： Griffin JW,Hsieh ST,McArthur JC,Cornblath DR

更新日期：1996-02-01 00:00:00

abstract：:The nervous system is involved in approximately 25% of patients with classical Wegener's granulomatosis. The spectrum of this disease has been broadened with the discovery of the anti-neutrophil cytoplasmic antibodies, which are found in diseases sharing many clinical features. The ANCA testing may indicate a common m...

journal_title：Neurologic clinics

authors： Jaffe IA

更新日期：1997-11-01 00:00:00

abstract：:Despite major medical advances, such as the introduction of the rubella vaccine and prolonged postnatal therapy of infants with congenital toxoplasmosis, intrauterine infections remain important causes of deafness, vision loss, and behavioral or neurologic disorders among children worldwide. This article describes the...

journal_title：Neurologic clinics

authors： Bale JF Jr

更新日期：2002-11-01 00:00:00

abstract：:We believe that our present understanding of these syndromes is insufficient to separate CIDP from MMN clearly and consider MMN to be a remarkably multifocal, predominantly motor variant of CIDP with the very unusual electrophysiologic feature of conduction block confined to motor axons. Further studies are clearly ne...

journal_title：Neurologic clinics

authors： Parry GJ,Sumner AJ

更新日期：1992-08-01 00:00:00

abstract：:The oldest-old represent the fastest growing segment of society, and the risk of developing dementia continues to increase with advancing age into the 9th and 10th decades of life. The most common form of dementia in the oldest-old is Alzheimer disease (AD), although there are often mixed pathologies contributing to d...

journal_title：Neurologic clinics

authors： Pierce AL,Bullain SS,Kawas CH

更新日期：2017-05-01 00:00:00

abstract：:Antidepressants are the most commonly prescribed class of medications in the United States. The clinician should be mindful of the many antidepressants that can produce seizures following an accidental exposure or an overdose. A broader understanding of the seizure potential of antidepressants, combined with the abili...

journal_title：Neurologic clinics

authors： Judge BS,Rentmeester LL

更新日期：2011-08-01 00:00:00

abstract：:Amyotrophic lateral sclerosis can be described as a disease with a poorly understood pathophysiologic mechanism and no treatment that dramatically impacts the course of the disease. Clinical trialists are faced with finding small treatment effects against a background of multiple potential treatments, a past history o...

journal_title：Neurologic clinics

authors： Katz JS,Barohn RJ,Dimachkie MM,Mitsumoto H

更新日期：2015-11-01 00:00:00

abstract：:Disorders of the autonomic and small nerve fibers comprise a wide spectrum of disease states that cross a multitude of clinical specialties.The evaluation of these disorders allows the investigator to determine the presence or absence of abnormalities in the lightly myelinated and unmyelinated nerve fibers with minima...

journal_title：Neurologic clinics

authors： Gibbons C,Freeman R

更新日期：2004-08-01 00:00:00

abstract：:Most CNS fungal infections can be divided into those that occur in normal hosts and those that occur in the immunosuppressed host. Cryptococcal infection, however, is common in both groups. The usual clinical presentation of a CNS fungal infection is chronic headache and mental status change. The CSF shows a lymphocyt...

journal_title：Neurologic clinics

authors： Lyons RW,Andriole VT

更新日期：1986-02-01 00:00:00

abstract：:Stroke involving the brainstem and cerebellum frequently presents acute vestibular syndrome. Although vascular vertigo is known to usually accompany other neurologic symptoms and signs, isolated vertigo from small infarcts involving the cerebellum or brainstem has been increasingly recognized. Bedside neuro-otologic e...

journal_title：Neurologic clinics

authors： Lee SH,Kim JS

更新日期：2015-08-01 00:00:00

abstract：:SEPs may be recorded over the spine and scalp to stimulation of any accessible mixed or sensory nerve in the extremities. SEP abnormalities are useful in detecting lesions in central somatosensory pathways. They do not establish a specific diagnosis, but they may suggest or support a diagnosis made on clinical grounds...

journal_title：Neurologic clinics

authors： Aminoff MJ

更新日期：1988-11-01 00:00:00

abstract：:Oromandibular disorders are functional disorders and associated pains in the anatomic region of the temporomandibular joint. Their diagnosis and treatment are controversial because of the lack of conformity concerning these disorders among health care providers. This article provides a clear classification of these di...

journal_title：Neurologic clinics

authors： Graff-Radford SB

更新日期：1990-11-01 00:00:00

abstract：:Myasthenia gravis is an autoimmune disorder characterized by fluctuating weakness of extraocular and proximal limb muscles. It occurs in 1 in 5000 in the overall population and is 2 times more common in women than men. The onset in women is most common in the third decade, and risk of severe exacerbation occurs most f...

journal_title：Neurologic clinics

authors： Waters J

更新日期：2019-02-01 00:00:00

abstract：:The criteria that characterize restless legs syndrome (RLS) and the differential diagnoses are discussed. Clinical signs include sleep disturbance, involuntary movements in sleep or wakefulness, a normal neurologic examination, a chronic clinical course, and, in some cases, a positive family history. Periodic limb mov...

journal_title：Neurologic clinics

authors： Trenkwalder C,Walters AS,Hening W

更新日期：1996-08-01 00:00:00