Pathology of multiple sclerosis.

abstract：:A specific genetic diagnosis can be reached for most children with muscular dystrophy. Advanced diagnostics, including genetic testing and analysis of nonmuscle tissues, such as skin and blood, often allow the diagnosis to be reached using minimally invasive procedures. These diagnostic advances accompany improved und...

journal_title：Neurologic clinics

authors： Mathews KD

更新日期：2003-11-01 00:00:00

abstract：:Selecting appropriate laboratory tests in diagnosing peripheral neuropathies is important because it increases the yield of correct diagnoses and is cost effective. A large number of tests are available. This article provides a guide to selecting appropriate tests and reviews the clinical situations that suggest speci...

journal_title：Neurologic clinics

authors： Griffin JW,Hsieh ST,McArthur JC,Cornblath DR

更新日期：1996-02-01 00:00:00

abstract：:The appropriate diagnosis of the patient with epilepsy is first dependent on a determination of the type of seizure. When the type of seizure has been determined, consideration must be given to the nature of the epileptic syndrome, including concerns regarding the etiology of the attacks. The gradual evolution of the ...

journal_title：Neurologic clinics

authors： Porter RJ

更新日期：1986-08-01 00:00:00

abstract：:Myopathies are a heterogeneous group of disorders that can be challenging to diagnose. This review provides a diagnostic approach based predominantly on the clinical history and neurologic examination. Laboratory testing that can be used to confirm the suspected diagnosis based on this pattern recognition approach is ...

journal_title：Neurologic clinics

authors： Barohn RJ,Dimachkie MM,Jackson CE

更新日期：2014-08-01 00:00:00

abstract：:In this article, the authors provide a conceptual framework in which to consider alternative approaches to identify the developmental consequences of exposing the developing brain to neurotoxic substances. Concepts underlying brain development and issues regarding neurobehavioral testing in children are reviewed. In a...

journal_title：Neurologic clinics

authors： Trask CL,Kosofsky BE

更新日期：2000-08-01 00:00:00

abstract：:Electronystagmography in 1990 should identify a vestibular abnormality with which to associate the clinical symptoms. The vestibular test battery method and interpretation reveals its application in neurotologic diagnosis. ...

journal_title：Neurologic clinics

authors： Brookler KH

更新日期：1990-05-01 00:00:00

abstract：:Use of the somatosensory evoked potential (SEP) in the evaluation of the peripheral nervous system is described. When using SEPs to evaluate peripheral nervous system disease, it is assumed that the central nervous system is intact. SEPs can be used to measure conduction through nerves that, by nature of their anatomi...

journal_title：Neurologic clinics

authors： Eisen A

更新日期：1988-11-01 00:00:00

abstract：:The respiratory system and the central nervous system are interconnected in a delicate balance; disorders in this equilibrium can have devastating consequences. Respiratory dysfunction, whether acute or chronic, may cause neurologic disease, including headache, encephalopathy, and in extreme cases, coma and death. Thi...

journal_title：Neurologic clinics

authors： Kirsch DB,Józefowicz RF

更新日期：2002-02-01 00:00:00

abstract：:Although intravenous thrombolysis with recombinant tissue plasminogen activator is a proven effective therapy for acute ischemic stroke, it is often insufficient to achieve recanalization in patients with large intracranial artery occlusions. In these cases, intra-arterial reperfusion techniques may be useful. Intra-a...

journal_title：Neurologic clinics

authors： Cohen JE,Leker RR,Rabinstein A

更新日期：2013-08-01 00:00:00

abstract：:In a recent trial limited to arteriovenous malformations discovered not to have bled, medical management was superior to medical management plus intervention. The trial was halted after 226 randomizations and a mean follow-up of 3.3 years owing to a disparity favoring the medical arm. Eligible patients were selected a...

journal_title：Neurologic clinics

authors： Mohr JP,Yaghi S

更新日期：2015-05-01 00:00:00

abstract：:Throughout pregnancy and the puerperium, a variety of hormonal and physiologic changes occur that are associated with pregnancy-specific neurologic conditions, which may also influence known preexisting medical conditions or bring previously unknown neurologic conditions to clinical attention. This article reviews the...

journal_title：Neurologic clinics

authors： Delfyett WT,Fetzer DT

更新日期：2012-08-01 00:00:00

abstract：:Pseudotumor cerebri is a perplexing syndrome of increased intra-cranial pressure without a space-occupying lesion. The terminology for the disorder has changed over the years and the diagnostic criteria revised to reflect advances in diagnostic technology and insights into the disease process. The classification and n...

journal_title：Neurologic clinics

authors： Friedman DI

更新日期：2004-02-01 00:00:00

abstract：:Primary angiitis of the central nervous system (PACNS) is a vasculitis of small arteries and veins of unknown cause restricted to the central nervous system (CNS), and controversy and disagreement exist over the means to establish the diagnosis. Cerebral arteriography, cerebrospinal fluid examination, and MRI singly o...

journal_title：Neurologic clinics

authors： Powers WJ

更新日期：2015-05-01 00:00:00

abstract：:The anatomic and physiologic changes that occur during pregnancy are unique. A neurologist needs to be aware of normal pregnancy-induced physiologic changes in the cardiovascular, renal, hematologic, and autoimmune systems, and the local anatomic changes, which include alteration of body habitus and pelvic ligaments. ...

journal_title：Neurologic clinics

authors： O'Neal MA

更新日期：2016-08-01 00:00:00

abstract：:Tuberous sclerosis is a multisystem disorder characterized by changes primarily involving the skin, eye, and central nervous system. Although the disease often produces mental retardation and seizures, this is not universal, and some patients with tuberous sclerosis lead a relatively normal life. ...

journal_title：Neurologic clinics

authors： Hanno R,Beck R

更新日期：1987-08-01 00:00:00

abstract：:Motor fluctuations and dyskinesias are common motor complications that manifest within the first few years from the initiation of therapy in patients with Parkinson disease. These complications negatively affect the quality of life and represent an important source of disability. A growing number of therapeutic option...

journal_title：Neurologic clinics

authors： Espay AJ

更新日期：2010-11-01 00:00:00

abstract：:A large body of medical and ethical opinion holds that it is justifiable to terminate medical treatment for permanently unconscious persons. But opponents of particular decisions to withhold or withdraw treatment may argue that the decisions violate laws against homicide, pose a threat to the lives of other less sever...

journal_title：Neurologic clinics

authors： Beresford HR

更新日期：1989-11-01 00:00:00

abstract：:Meaningful symptom management can have a profound impact on quality of life. It can challenge time parameters during clinic, and therefore thought should be given to strategies that can improve efficiency and thereby make the undertaking more tenable. For any given symptom, the building blocks of care, such as vitamin...

journal_title：Neurologic clinics

authors： Crabtree-Hartman E

更新日期：2018-02-01 00:00:00

abstract：:Face recognition is one of the most complex visual tasks performed by the human brain. Data from monkeys suggest that area IT may play a key role in identifying faces, and functional imaging research suggests that the human homologue of IT may be located in the medial occipitotemporal cortex, where a FFA has been loca...

journal_title：Neurologic clinics

authors： Barton JJ

更新日期：2003-05-01 00:00:00

abstract：:The last 2 decades represent a period of unparalleled advancement in the understanding of the pathogenesis of Parkinson disease (PD). The discovery of several forms of familial parkinsonism with mendelian inheritance has elucidated insights into the mechanisms underlying the degeneration of dopaminergic neurons of the...

journal_title：Neurologic clinics

authors： Mullin S,Schapira AH

更新日期：2015-02-01 00:00:00

abstract：:The fourth edition of The Diagnostic and Statistical Manual of Mental Disorders defines delirium as "a reversible state of confusion with a reduced level of consciousness manifest as an inability to focus, sustain or shift attention." Pharmacologic agents are important contributors to delirium in hospitalized elderly ...

journal_title：Neurologic clinics

authors： Hanson MR,Gálvez-Jiménez N

更新日期：2004-05-01 00:00:00

abstract：:Neurologic emergencies are common among cancer patients and their incidence is increasing as patients live longer as a result of improved antineoplastic therapy. This article reviews acute neurologic complications in cancer patients. Among those complications reviewed are brain metastases, epidural spinal cord compres...

journal_title：Neurologic clinics

authors： Schiff D,Batchelor T,Wen PY

更新日期：1998-05-01 00:00:00

abstract：:Primary brain tumors consist of neoplasms with varied molecular defects, morphologic phenotypes, and clinical outcomes. The genetic and signaling abnormalities involved in tumor initiation and progression of the most prevalent adult primary brain tumors, including gliomas, meningiomas, and medulloblastomas, are descri...

journal_title：Neurologic clinics

authors： Sauvageot CM,Kesari S,Stiles CD

更新日期：2007-11-01 00:00:00

abstract：:A recently described syndrome, disabling positional vertigo (DPV), is characterized by persistent and progressive vertigo that is always associated with nausea and occasionally with vomiting; symptoms are made worse with changes in head position and are lessened with bedrest. Patients with DPV have abnormal results on...

journal_title：Neurologic clinics

authors： Møller MB,Møller AR

更新日期：1990-05-01 00:00:00

abstract：:Despite important advances in the treatment of epilepsy over the past several decades, many patients remain uncontrolled. Partial complex (psychomotor) seizures are the largest problem, with less than two thirds of patients successfully managed despite optimal medication use. In these situations, various surgical proc...

journal_title：Neurologic clinics

authors： Spencer DD,Spencer SS

更新日期：1985-05-01 00:00:00

abstract：:A network of family-based community-oriented primary health programs, or Programa Agentes Communita˙rios de Saúde, and family health programs, or Programa Saúde da Família, introduced almost 2 decades ago were the Brazilian government's health care models to restructure primary care under the Unified Health System, or...

journal_title：Neurologic clinics

authors： Younger DS

更新日期：2016-11-01 00:00:00

abstract：:Neurologic complications are a major cause of morbidity, complicating open heart surgery, cardiac catheterization, and interventional techniques. Global or focal brain ischemia related to embolism or hypoperfusion predominates. Breakthrough cerebral hemorrhage and infection can complicate cardiac transplantation. Iden...

journal_title：Neurologic clinics

authors： Furlan AJ,Sila CA,Chimowitz MI,Jones SC

更新日期：1992-02-01 00:00:00

abstract：:Prions diseases are uniformly fatal neurodegenerative diseases that occur in sporadic, genetic, and acquired forms. Acquired prion diseases, caused by infectious transmission, are least common. Most prion diseases are not infectious, but occur spontaneously through misfolding of normal prion proteins or genetic mutati...

journal_title：Neurologic clinics

authors： Tee BL,Longoria Ibarrola EM,Geschwind MD

更新日期：2018-11-01 00:00:00

abstract：:The presence of a monoclonal protein in the serum of a patient with peripheral neuropathy raises the suspicion of systemic amyloidosis, POEMS syndrome, macroglobulinemia, multiple myeloma, or lymphoma. If these conditions are excluded, the patient is classified as having a monoclonal gammopathy of undetermined signifi...

journal_title：Neurologic clinics

authors： Kyle RA

更新日期：1992-08-01 00:00:00

abstract：:As in most areas of clinical medicine, the history often is the key to determining the diagnosis in patients presenting with neurotologic symptoms. The most common cause of vertigo--benign positional vertigo--can be diagnosed at the bedside based on the characteristic history and the finding of fatigable positional ny...

journal_title：Neurologic clinics

authors： Baloh RW,Jacobson KM

更新日期：1996-02-01 00:00:00