Management of unbled brain arteriovenous malformation study.

Abstract:

:In a recent trial limited to arteriovenous malformations discovered not to have bled, medical management was superior to medical management plus intervention. The trial was halted after 226 randomizations and a mean follow-up of 3.3 years owing to a disparity favoring the medical arm. Eligible patients were selected as suitable for lesion eradication. The initial sample size of 800 and follow-up plans for a mean of 7 years were lowered and shortened, respectively, by the outcome data. An application for extended follow-up was given poor priority scores owing to estimations that the disparities in outcomes would not change significantly.

journal_name

Neurol Clin

journal_title

Neurologic clinics

authors

Mohr JP,Yaghi S

doi

10.1016/j.ncl.2014.12.006

subject

Has Abstract

pub_date

2015-05-01 00:00:00

pages

347-59

issue

2

eissn

0733-8619

issn

1557-9875

pii

S0733-8619(14)00122-4

journal_volume

33

pub_type

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